Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Leitung: Prof. Dr. med. Michael D. Menger
Publikationen 2020

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Ampofo E, Nalbach L, Menger MD, Laschke MW.

Regulatory Mechanisms of Somatostatin Expression.

Int J Mol Sci. 2020;21(11):E4170.


Ampofo E, Später T, Nalbach L, Menger MD, Laschke MW.

The Marine-Derived Triterpenoid Frondoside A Inhibits Thrombus Formation.

Mar Drugs. 2020;14;18(2):111.


Assuncão M, Dehghan-Baniani D, Yiu CHK., Später T, Beyer S, Blocki A.

Cell-Derived Extracellular Matrix for Tissue Engineering and Regenerative Medicine.

Front Bioeng Biotech. 2020;8:602009.


Dudenhöffer DW, Laschke MW, Giebels C, Karliova I, Schneider U, Menger MD, Schäfers HJ.

In vivo biocompatibility of a novel expanded polytetrafluoroethylene suture for annuloplasty.

Thorac Cardiovasc Surg. 2020;68(7):575-583.


Fritz T, Ducommun P, Pohlemann T, Calcagni M, Tschernig T, Menger MD, Metzger W, Frueh FS.

Flexor tendon grafts for pulley reconstruction - Morphological aspects.

Ann Anat. 2020; 231:151550.


Frueh FS, Gousopoulos E, Power DM, Ampofo E, Giovanoli P, Calcagni M, Laschke MW.

A potential role of lymphangiogenesis for peripheral nerve injury and regeneration.

Med Hypotheses. 2020; 135:109470.


Frueh FS, Jelvani B, Scheuer C, Körbel C, Kim BS, Giovanoli P, Lindenblatt N, Harder Y, Ampofo E, Menger MD, Laschke MW.

Short-term molecular and cellular effects of ischemia/reperfusion on vascularized lymph node flaps in rats.

PLoS One. 2020;15:eO239517.


Haupenthal J, Kautz Y, Elgaher WAM, Pätzold L, Röhrig T, Laschke MW, Tschernig T, Hirsch AKH, Molodtsov V, Murakami KS, Hartmann RW, Bischoff M.

Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus - Based Wound Infection Model in SKH1 Mice.

Acs Infect Dis. 2020;6:2573-2581.


Höfer D, Körbel C, Laschke MW, Veith NT, Pohlemann T, Kappl R, Tschernig T.

Experimental induction of blunt ehest trauma in mice: A modified approach with evaluation in dummies and cadavers.

Exp Ther Med. 2020;20:28.


Lesch A, Backes TM, Langfermann DS, Rössler OG, Laschke MW, Thiel G.

Ternary complex factor regulates pancreatic islet size and blood glucose homeostasis in transgenic mice.

Pharmacol Res. 2020;159:104983.


Linxweiler J, Hajili T, Körbel C, Berchem C, Zeuschner P, Müller A, Stöckle M, Menger MD, Junker K, Saar M.

Cancer-associated fibroblasts stimulate primary tumor growth and metastatic spread in an orthotopic prostate cancer xenograft model.

Sci Rep-Uk. 2020;10:12575.


Madry H, Gao L, Rey-Rico A, Venkatesan JK, Müller-Brandt K, Cai X, Goebel L, Schmitt G, Speicher-Mentges S, Zurakowski D, Menger MD, Laschke MW, Cucchiarini M

Thermosensitive Hydrogel Based on PEO-PPO-PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno-Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects.

Adv Mater.2020; 32(2):e1906508.


Menger MM, Bremer P, Scheuer C, Rollmann MF, Braun BJ, Herath SC, Orth M, Später T, Pohlemann T, Menger MD, Histing T.

Pantoprazole impairs fracture healing in aged mice.

Sci Rep-Uk. 2020;10:22376.


Menger MM, Nalbach L, Roma LP, Körbel C, Wrublewsky S, Glanemann M, Laschke MW, Menger MD, Ampofo E.

Erythropoietin accelerates the revascularization of transplanted pancreatic islets.

Br J Pharmacol.2020;177(7):1651-1665.


Menger MM, Nalbach L, Wrublewsky S, Glanemann M, Gu Y, Laschke MW, Menger MD, Ampofo E

Darbepoetin-α increases the blood volume flow in transplanted pancreatic islets in mice.

Acta Diabetol. 2020; 28. Online ahead of print.


Nalbach L, Roma LP, Schmitt BM, Becker V, Körbel C, Wrublewsky S, Pack M, Später T, Metzger W, Menger MM, Frueh FS, Götz C, Lin H, Em Fox J, MacDonald PE, Menger MD, Laschke MW, Ampofo E

Improvement of islet transplantation by the fusion of islet cells with functional blood vessels

EMBO Mol Med.2020;57:1009-1018.


Nordmeier F, Doerr A, Laschke MW, Menger MD, Schmidt PH, Schaefer N, Meyer MR

Are pigs a suitable animal model for in vivo metabolism studies of new psychoactive substances? A comparison study using different in vitro/in vivo tools and U-47700 as model drug.

Toxicol Lett. 2020 1;329:12-19.


Rudzitis-Auth J, Fuß SA, Becker V, Menger MD, Laschke MW

Inhibition of erythropoietin-producing hepatoma receptor B4 (EphB4) signalling suppresses the vascularisation and growth of endometriotic lesions.

Br J Pharmacol. 2020; 177:3225-3239.


Schaefer N, Kröll AK, Körbel C, Laschke MW, Menger MD, Maurer HH, Meyer MR, Schmidt PH

Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs.

Arch Toxicol. 2020;94(5):1585-1599.


Schaefer N, Nordmeier F, Kröll AK, Körbel C, Laschke MW, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as A9-tetrahydrocannabinol to pigs.

Arch Toxicol. 2020;94:3421-3431.


Scheuer R, Philipp SE, Becker A, Nalbach L, Ampofo E, Montenarh M, Götz C

Protein Kinase CK2 Controls CaV2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-Cells.

Int J Mol Sci. 2020;21:4668.


Schmitt BM, Ampofo E, Stumpf H, Montenarh M, Götz C

The stability of CREB3/Luman is regulated by protein kinase CK2 phosphorylation.

Biochem Biophys Res Commun. 2020;523:639-644.


Schmitt BM, Boewe AS, Becker V, Nalbach L, Gu Y, Götz C, Menger MD, Laschke MW, Ampofo E

Protein Kinase CK2 Regulates Nerve/Glial Antigen (NG)2-Mediated Angiogenic Activity of Human Pericytes.

Cells. 2020;9:1546.


Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y

Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.

FASEB J. 2020; 34:9628-9649


Simgen A, Kettner M, Dietrich P, Tomori T, Mühl-Benninghaus R, Bhogal P, Laschke MW, Menger MD, Reith W, Yilmaz U

Different Rescue Approaches of Migrated Woven Endobridge (WEB) Devices: an Animal Study.

Clin Neuroradiol. 2020 12. Online ahead of print.


Simgen A, Yilmaz U, Dietrich P, Tomori T, Mühl-Benninghaus R, Laschke MW, Menger MD, Reith W, Kettner M

Rescue of migrated Woven Endobridge devices using a stent-retriever-technique in a porcine model.

Interv Neuroradiol. 2020; 26:772-778.


Später T, Ampofo E, Menger MD, Laschke MW

Combining Vascularization Strategies in Tissue Engineering: The Faster Road to Success?

Front Bioeng Biotech. 2020;8:592095.


Später T, Mariyanats AO, Syachina MA, Mironov AV, Savelyev AG, Sochilina AV, Menger MD, Vishnyakova PA, Kananykhina EY, Fatkhudinov TK, Sukhikh GT, Spitkovsky DD, Katsen-Globa A, Laschke MW, Popov VK.

In Vitro and in Vivo Analysis of Adhesive, Anti-Inflammatory, and Proangiogenic Properties of Novel 3D Printed Hyaluronic Acid Glycidyl Methacrylate Hydrogel Scaffolds for Tissue Engineering.

Acs Biomater Sci Eng. 2020;6:5744-5757.


Später T, Menger MM, Nickels RM, Menger MD, Laschke MW

Macrophages promote network formation and maturation of transplanted adipose tissue-derived microvascular fragments.

J Tissue Eng. 2020 9;11:2041731420911816.


Später T, Tobias AL, Menger MM, Nickels RM, Menger MD, Laschke MW.

Biological coating with platelet-rich plasma and adipose tissue-derived microvascular fragments improves the vascularization, biocompatibility and tissue incorporation of porous polyethylene.

Acta Biomater. 2020; 108:194-206.


Vilas-Boas EA, Karabacz N, Marsiglio-Librais GN, Valle MMR, Nalbach L, Ampofo E, Morgan B, Carpinelli AR, Roma LP.

Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function.

Pharmacol Rep. 2020;72:1725-1737.


Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Körbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Aßmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, März W, Böhm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U, Speer T.

Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.

Nat Immunol. 2020;21(1):30-41.