Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Leitung: Prof. Dr. med. Michael D. Menger
Publikationen 2008

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Abshagen K, Eipel C, Kalff JC, Menger MD, Vollmar B.
Kupffer cells are mandatory for adequate liver regeneration by mediating hyperperfusion via modulation of vasoactive proteins.


Benninger E, Labler L, Seifert B, Trentz O, Menger MD, Meier C.

In vitro comparison of intra-abdominal hypertension development after different temporary abdominal closure techniques.

J Surg Res. 2008;144:102-6.

Braun OO, Slotta JE, Menger MD, Erlinge D, Thorlacius H.

Primary and secondary capture of platelets onto inflamed femoral artery endothelium is dependent on P-selectin and PSGL-1.

Eur J Pharmacol.2008;592:128-32.

Burkhardt M, Slotta JE, Garcia P, Seekamp A, Menger MD, Pohlemann T.

The effect of estrogen on hepatic microcirculation after ischemia/reperfusion.

Int J Colorectal Dis. 2008;23:113-9.

Cantré D, Schuett H, Hildebrandt A, Dold S, Menger MD, Vollmar B, Eipel C.

Nitric oxide reduces organ injury and enhances regeneration of reduced-size livers by increasing hepatic arterial flow.

Br J Surg.2008;95:785-92.

Demertzis SD, Laschke MW, Siclari FP, Menger MD.

Non-robotic thoracoscopic internal mammary artery preparation in the pig. A training model.
Interact Cardiovasc Thorac Surg.2008;7:556-9.

Dold S, Laschke MW, Lavasani S, Menger MD, Thorlacius H.

Cholestatic liver damage is mediated by lymphocyte function antigen-1-dependent recruitment of leukocytes.

Surgery. 2008;144:385-93.

Garcia P, Holstein JH, Histing T, Burkhardt M, Culemann U, Pizanis A, Wirbel RJ, Pohlemann T, Menger MD.

A new technique for internal fixation of femoral fractures in mice: impact of stability on fracture healing.

J Biomech.2008;41:1689-96.

Garcia P, Holstein JH, Maier S, Schaumlöffel H, Al-Marrawi F, Hannig M, Pohlemann T, Menger MD.

Development of a reliable non-union model in mice.

J Surg Res.2008;147:84-91.

Gierer P, Hoffmann JN, Mahr F, Menger MD, Mittlmeier T, Gradl G, Vollmar B.

Sublethal trauma model with systemic endotoxemia for the study of microcirculatory disorders after the second hit.

J Surg Res. 2008;147:68-74.

Harder Y, Amon M, Laschke MW, Schramm R, Rücker M, Wettstein R, Bastiaanse J, Frick A, Machens HG, Küntscher M, Germann G, Vollmar B, Erni D, Menger MD.

An old dream revitalised: preconditioning strategies to protect surgical flaps from critical ischaemia and ischaemia-reperfusion injury.

J Plast Reconstr Aesthet Surg.2008;61:503-11.

Harder Y, Amon M, Schramm R, Rücker M, Scheuer C, Pittet B, Erni D, Menger MD.

Ischemia-induced up-regulation of heme oxygenase-1 protects from apoptotic cell death and tissue necrosis.

J Surg Res.2008;150:293-303.

Hoffman JN, Fertmann JM, Vollmar B, Laschke MW, Jauch KW, Menger MD.

Immunoglobulin M-enriched human intravenous immunoglobulins reduce leukocyte-endothelial cell interactions and attenuate microvascular perfusion failure in normotensive endotoxemia.


Holstein JH, Klein M, Garcia P, Histing T, Culemann U, Pizanis A, Laschke MW, Scheuer C, Meier C, Schorr H, Pohlemann T, Menger MD.

Rapamycin affects early fracture healing in mice.

Br J Pharmacol.2008;154:1055-62.

Klemm K, Eipel C, Cantré D, Abshagen K, Menger MD, Vollmar B.

Multiple doses of erythropoietin impair liver regeneration by increasing TNF-alpha, the Bax to Bcl-xL ratio and apoptotic cell death.

PLoS ONE.2008;3:e3924.

Kollmar O, Junker B, Rupertus K, Scheuer C, Menger MD, Schilling MK.

Liver resection-associated macrophage inflammatory protein-2 stimulates engraftment but not growth of colorectal metastasis at extrahepatic sites.

J Surg Res. 2008;145:295-302.

Kuhla A, Eipel C, Siebert N, Abshagen K, Menger MD, Vollmar B.

Hepatocellular apoptosis is mediated by TNFalpha-dependent Fas/FasLigand cytotoxicity in a murine model of acute liver failure.


Laschke MW, Rücker M, Jensen G, Carvalho C, Mülhaupt R, Gellrich NC, Menger MD.

Improvement of vascularization of PLGA scaffolds by inosculation of in situ-preformed functional blood vessels with the host microvasculature.

Ann Surg.2008;248:939-48.

Laschke MW, Schwender C, Scheuer C, Vollmar B, Menger MD.

Dietary glycine does not affect physiological angiogenesis and reproductive function, but inhibits apoptosis in endometrial and ovarian tissue by down-regulation of nuclear factor-kappaB.

Fertil Steril.2008;90:1460-9.

Laschke MW, Schwender C, Scheuer C, Vollmar B, Menger MD.

Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo.

Hum Reprod.2008;23:2308-18.

Laschke MW, Dold S, Menger MD, Jeppsson B, Thorlacius H.

Platelet-dependent accumulation of leukocytes in sinusoids mediates hepatocellular damage in bile duct ligation-induced cholestasis.

Br J Pharmacol.2008;153:148-56.

Laschke MW, Rücker M, Jensen G, Carvalho C, Mülhaupt R, Gellrich NC, Menger MD.

Incorporation of growth factor containing Matrigel promotes vascularization of porous PLGA scaffolds.

J Biomed Mater Res A.2008;85:397-407.

Lindenblatt N, Calcagni M, Contaldo C, Menger MD, Giovanoli P, Vollmar B.

A New Model for Studying the Revascularization of Skin Grafts In Vivo: The Role of Angiogenesis.

Plast Reconstr Surg.2008;122:1669-80.

Moussavian MR, Slotta JE, Kollmar O, Menger MD, Gronow G, Schilling MK.

Post-hypoxic cellular disintegration in glycine-preserved renal tubules is attenuated by hydroxyl radical scavengers and iron chelators.

Langenbecks Arch Surg.2008;393:303-310.

Rezaeian F, Wettstein R, Amon M, Scheuer C, Schramm R, Menger MD, Pittet B, Harder Y.

Erythropoietin protects critically perfused flap tissue.

Ann Surg.2008;248:919-29.

Roller J, Laschke MW, Sethi S, Herrmann M, Menger MD.

Prolene-Monocryl-composite meshes do not increase microvascular Staphylococcus aureus adherence and do not sensitize for leukocytic inflammation.

Langenbecks Arch Surg.2008;393:349-57.

Rücker M, Laschke MW, Junker D, Carvalho C, Tavassol F, Mülhaupt R, Gellrich NC, Menger MD.

Vascularization and biocompatibility of scaffolds consisting of different calcium phosphate compounds.

J Biomed Mater Res A.2008,86:1002-11.

Santen S, Wang Y, Menger MD, Jeppsson B, Thorlacius H.

Mast-cell-dependent secretion of CXC chemokines regulates ischemia-reperfusion-induced leukocyte recruitment in the colon.

Int J Colorectal Dis.2008;23:527-534.

Seehofer D, Neumann UP, Schirmeier A, Carter J, Cho SY, Lederer A, Rayes N, Menger MD, Nüssler AK, Neuhaus P.

Synergistic effect of erythropoietin but not G-CSF in combination with curcumin on impaired liver regeneration in rats.

Langenbecks Arch Surg.2008;393:325-32.

Slotta JE, Laschke MW, Menger MD, Thorlacius H.

Rho-kinase signalling mediates endotoxin hypersensitivity after partial hepatectomy.

Br J Surg.2008;95:976-84.

Slotta JE, Braun OO, Menger MD, Thorlacius H.

Central role of rho kinase in lipopolysaccharide-induced platelet capture on venous endothelium.

J Investig Med.2008;56:720-5.

Szabó A, Vollmar B, Boros M, Menger MD.

In vivo fluorescence microscopic imaging for dynamic quantitative assessment of intestinal mucosa permeability in mice.

J Surg Res. 2008;145(2):179-85.

Vollmar B, Franke K, Menger MD.

Nutritive perfusion of pancreatic endocrine tissue during hemorrhagic hypotension: how differ islets in situ from islet isografts?

Shock. 2008;30:428-33.