Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Leitung: Prof. Dr. med. Michael D. Menger
Publikationen 2010

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Benninger E, Laschke MW, Cardell M, Holstein JH, Seifert B, Keel M, Trentz O, Menger MD, Meier C.

Compartment pressure of the rectus sheath accurately reflects intra-abdominal pressure in a porcine model.

J Surg Res. 2010;161:295-300.

Dold S, Laschke MW, Zhau Y, Schilling M, Menger MD, Jeppsson B, Thorlacius H.

P-selectin glycoprotein ligand-1-mediated leukocyte recruitment regulates hepatocellular damage in acute obstructive cholestasis in mice.

Inflamm Res. 2010;59:291-8.

Ehrmantraut S, Laschke MW, Merkel D, Scheuer C, Willnecker V, Meyer-Lindenberg A, Menger MD, Naumann A.

Perioperative steroid administration inhibits angiogenic host tissue response to porous polyethylene (Medpor) implants.

Eur Cell Mater. 2010;19:107-16.

Eipel C, Abshagen K, Ritter J, Cantré D, Menger MD, Vollmar B.

Splenectomy improves survival by increasing arterial blood supply in a rat model of reduced-size liver.

Transpl Int. 2010;23:998-1007.

Esguerra M, Fink H, Laschke MW, Jeppsson A, Delbro D, Gatenholm P, Menger MD, Risberg B.
Intravital fluorescent microscopic evaluation of bacterial cellulose as scaffold for vascular grafts.
J Biomed Mater Res A. 2010;93:140-9.

Fozing T, Scheuer C, Samnick S.

Synthesis and initial tumor affinity testing of iodine-123 labelled EGFR-affine agents as potential imaging probes for hormone-refractory prostate cancer.

Eur J Med Chem. 2010;45:3780-6

Garcia P, Histing T, Holstein JH, Pohlemann T, Menger MD.

Femoral non-union models in the mouse.

Injury. 2010;41:1158-9.

Garcia P, Schwenzer S, Slotta JE, Scheuer C, Tami AE, Holstein JH, Histing T, Burkhardt M, Pohlemann T, Menger MD.

Inhibition of angiotensin-converting enzyme stimulates fracture healing and periosteal callus formation - role of a local renin-angiotensin system.

Br J Pharmacol. 2010;159:1672-80.

Harder Y, Amon M, Wettstein R, Rücker M, Schramm R, Menger MD.

Gender-specific ischemic tissue tolerance in critically perfused skin.

Langenbecks Arch Surg. 2010;395:33-40.

Histing T, Kristen A, Roth C, Holstein JH, Garcia P, Matthys R, Menger MD, Pohlemann T.

In vivo gait analysis in a mouse femur fracture model.

J Biomech. 2010;43:3240-3.

Histing T, Garcia P, Matthys R, Leidinger M, Holstein JH, Kristen A, Pohlemann T, Menger MD.

An internal locking plate to study intramembranous bone healing in a mouse femur fracture model.

J Orthop Res. 2010;28:397-402.

Holstein JH, Herrmann M, Splett C, Herrmann W, Garcia P, Histing T, Klein M, Kurz K, Siebel T, Pohlemann T, Menger MD.

Hyperhomocysteinemia is not associated with reduced bone quality in humans with hip osteoarthritis.

Clin Chem Lab Med. 2010;48:821-7.

Holstein JH, Herrmann M, Schmalenbach J, Obeid R, Olkü I, Klein M, Garcia P, Histing T, Pohlemann T, Menger MD, Herrmann W, Claes L.

Deficiencies of folate and vitamin B12 do not affect fracture healing in mice.

Bone. 2010;47:151-5.

Körbel C, Menger MD, Laschke MW.

Size and spatial orientation of uterine tissue transplants on the peritoneum crucially determine the growth and cyst formation of endometriosis-like lesions in mice.

Hum Reprod. 2010;25:2551-8.

Kollmar O, Rupertus K, Scheuer C, Nickels RM, Haberl GC, Tilton B, Menger MD, Schilling MK.

CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1.

Int J Cancer. 2010;126:1302-15.

Kollmar O, Corsten M, Scheuer C, Vollmar B, Schilling MK, Menger MD.

Tumour growth following portal branch ligation in an experimental model of liver metastases.

Br J Surg. 2010;97:917-26.

Kuhla A, Hettwer C, Menger MD, Vollmar B.

Oxidative stress-associated rise of hepatic protein glycation increases inflammatory liver injury in uncoupling protein-2 deficient mice.

Lab Invest. 2010;90:1189-98.

Laschke MW, Mussawy H, Schuler S, Eglin D, Alini M, Menger MD.

Promoting external inosculation of prevascularised tissue constructs by pre-cultivation in an angiogenic extracellular matrix.

Eur Cell Mater. 2010;20: 356-6.

Laschke MW, Dold S, Jeppsson B, Schilling MK, Menger MD, Thorlacius H.

Rho-kinase inhibitor attenuates cholestasis-induced CXC chemokine formation, leukocyte recruitment, and hepatocellular damage in the liver.

J Surg Res. 2010;159:666-73.

Laschke MW, Körbel C, Rudzitis-Auth J, Gashaw I, Reinhardt M, Hauff P, Zollner TM, Menger MD.

High-resolution ultrasound imaging: a novel technique for the noninvasive in vivo analysis of endometriotic lesion and cyst formation in small animal models.

Am J Pathol. 2010;176:585-93.

Laschke MW, Schwender C, Vollmar B, Menger MD.

Genistein does not affect vascularization and blood perfusion of endometriotic lesions and ovarian follicles in dorsal skinfold chambers of Syrian golden hamsters.

Reprod Sci. 2010;17:568-77.

Laschke MW, Strohe A, Menger MD, Alini M, Eglin D.

In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester-urethane) composite scaffold for bone tissue engineering.

Acta Biomater. 2010;6:2020-7.

Lindhorst D, Tavassol F, von See C, Schumann P, Laschke MW, Harder Y, Bormann KH, Essig H, Kokemüller H, Kampmann A, Voss A, Mülhaupt R, Menger MD, Gellrich NC, Rücker M.

Effects of VEGF loading on scaffold-confined vascularization.

J Biomed Mater Res A. 2010;95:783-92.

Madry H, Orth P, Kaul G, Zurakowski D, Menger MD, Kohn D, Cucchiarini M.

Acceleration of articular cartilage repair by combined gene transfer of human insulin-like growth factor I and fibroblast growth factor-2 in vivo.

Arch Orthop Trauma Surg. 2010;130:1311-22.

Rezaeian F, Wettstein R, Egger JF, Sandmann F, Rücker M, Tobalem M, Vollmar B, Menger MD, Harder Y.

Erythropoietin-induced upregulation of endothelial nitric oxide synthase but not vascular endothelial growth factor prevents musculocutaneous tissue from ischemic damage.

Lab Invest. 2010;90:40-51.

Richter S, Sperling J, Kollmar O, Menger MD, Schilling MK.

Laser Doppler Flowmetry of Hepatic Microcirculation during Pringle's Maneuver: Determination of Spatial and Temporal Liver Tissue Perfusion Heterogeneity.

Eur Surg Res. 2010;44:152-8.


Roller J, Laschke MW, Scheuer C, Menger MD.

Heme oxygenase (HO)-1 protects from lipopolysaccharide (LPS)-mediated liver injury by inhibition of hepatic leukocyte accumulation and improvement of microvascular perfusion.

Langenbecks Arch Surg. 2010; 395:387-94.


Rupertus K, Sperling J, Corsten M, Scheuer C, Nickels RM, Schilling MK, Menger MD, Kollmar O.

Darbepoetin-alpha Enhances Hepatectomy-Associated Stimulation of Colorectal Liver Metastatic Growth.

Ann Surg. 2010; 252:131-41.


Santen S, Wang Y, Laschke MW, Menger MD, Jeppsson B, Thorlacius H.

Rho-kinase signalling regulates CXC chemokine formation and leukocyte recruitment in colonic ischemia-reperfusion.

Int J Colorectal Dis. 2010;25:1063-70.

Schäfer T, Sperling J, Kollmar O, Richter S, Schilling MK, Menger MD, Lindemann W.

Early effect of hepatic artery TNF-alpha infusion on systemic hemodynamics and inflammation: a dose-response study in pigs.

Int J Colorectal Dis. 2010;25:523-32.

Schramm R, Kirsch S, Schäfers HJ, Langer F, Scheuer C, Nickels R, Harder Y, Menger MD.

Erythropoietin inhibits post-ischemic leukocyte adhesion but does not affect rejection in murine cardiac allografts.

J Heart Lung Transplant. 2010;29:1185-92.

Seehofer D, Schirmeier A, Bengmark S, Cho SY, Koch M, Lederer A, Rayes N, Menger MD, Neuhaus P, Nüssler AK.

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.

J Surg Res. 2010;159:497-502.

Slotta JE, Laschke MW, Schilling MK, Menger MD, Jeppsson B, Thorlacius H.

Simvastatin attenuates hepatic sensitization to lipopolysaccharide after partial hepatectomy.

J Surg Res. 2010;162:184-92.

Tavassol F, Schumann P, Lindhorst D, Sinikovic B, Voss A, von See C, Kampmann A, Bormann KH, Carvalho C, Mülhaupt R, Harder Y, Laschke MW, Menger MD, Gellrich NC, Rücker M.

Accelerated Angiogenic Host Tissue Response to Poly(L-Lactide-co-Glycolide) Scaffolds by Vitalization with Osteoblast-like Cells.

Tissue Eng Part A. 2010;16:2265-79.

Vollmar B, Eipel C, Menger MD.

Therapeutic effects of erythropoietin in murine models of endotoxin shock.

Crit Care Med. 2010;38:340-1.

Vollmar B, Menger MD.

Does experimental surgery still exist?

Chirurg. 2010;81:323-7.

von See C, Gellrich NC, Jachmann U, Laschke MW, Bormann KH, Rücker M.

Bone augmentation after soft-tissue expansion using hydrogel expanders: effects on microcirculation and osseointegration.

Clin Oral Implants Res. 2010;21:842-7.