Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Leitung: Prof. Dr. med. Michael D. Menger
Publikationen 2015

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Ampofo E, Müller I, Dahmke IN, Eichler H, Montenarh M, Menger MD, Laschke MW

Role of protein kinase CK2 in the dynamic interaction of platelets, leukocytes and endothelial cells during thrombus formation.

Thromb Res. 2015 Nov;136(5):996-1006.


Ampofo E, Rudzitis-Auth J, Dahmke IN, Rössler OG, Thiel G, Montenarh M, Menger MD, Laschke MW.

Inhibition of protein kinase CK2 suppresses tumor necrosis factor (TNF)-α-induced leukocyte-endothelial cell interaction.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2123-36.


Ampofo E, Später T, Müller I, Eichler H, Menger MD, Laschke MW

The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity.

Mar Drugs. 2015 Nov 9;13(11):6774-91.


Bomberg H, Bierbach B, Flache S, Novák M, Bandner-Risch D, Menger MD, Schäfers HJ.

Vasopressin aggravates cardiopulmonary bypass-induced gastric mucosal ischemia.

Eur Surg Res.2015; 54(1-2):75-86


Dold S, Richter S, Kollmar O, von Heesen M, Scheuer C, Laschke MW, Vollmar B, Schilling MK, Menger MD.

Portal Hyperperfusion after Extended Hepatectomy Does Not Induce a Hepatic Arterial Buffer Response (HABR) but Impairs Mitochondrial Redox State and Hepatocellular Oxygenation.

PLoS One.2015 Nov 2;10(11):e0141877.


Fries P, Morr D, Müller A, Lux F, Tillement O, Massmann A, Seidel R, Schäfer T, Menger MD, Schneider G, Bücker A.

Evaluation of a Gadolinium-Based Nanoparticle (AGuIX) for Contrast-Enhanced MRI of the Liver in a Rat Model of Hepatic Colorectal Cancer Metastases at 9.4 Tesla.

Rofo. 2015 Dec;187(12):1108-1115.


Fries P, Müller A, Seidel R, Robert P, Denda G, Menger MD, Schneider G, Buecker A.

P03277-A New Approach to Achieve High-Contrast Enhancement: Initial Results of an Experimental Extracellular Gadolinium-Based Magnetic Resonance Contrast Agent.

Invest Radiol. 2015 Dec;50(12):835-42.


Frueh FS, Gousopoulos E, Rezaeian F, Menger MD, Lindenblatt N, Giovanoli P.

Animal models in surgical lymphedema research-a systematic review.

J Surg Res. 2015 Jul 9. pii: S0022-4804(15)00750-7. [Epub ahead of print] Review.


Herath SC, Lion T, Klein M, Stenger D, Scheuer C, Holstein JH, Mörsdorf P, Rollmann MF, Pohlemann T, Menger MD, Histing T.

Stimulation of angiogenesis by cilostazol accelerates fracture healing in mice.

J Orthop Res. 2015 Dec;33(12):1880-7.


Kazakov A, Meier T, Werner C, Hall R, Klemmer B, Körbel C, Lammert F, Maack C, Böhm M, Laufs U.

C-kit (+) resident cardiac stem cells improve left ventricular fibrosis in pressure overload.

Stem Cell Res.2015 Nov;15(3):700-11.


Klein M, Stieger A, Stenger D, Scheuer C, Holstein JH, Pohlemann T, Menger MD, Histing T.
Comparison of healing process in open osteotomy model and open fracture model: Delayed healing of osteotomies after intramedullary screw fixation.
J Orthop Res. 2015 Jul;33(7):971-8.


Körbel C, Jung V, Kamradt J, Stöckle M, Unteregger G, Menger MD, Saar M.

High-Resolution Ultrasound Allows Percutaneous Initiation and Surveillance of Prostate Cancer in an Orthotopic Murine Model.

Urol Int.2015;94(3):347-53.


Kulas P., Willnecker V., Dlugaiczyk J., Laschke M.W., Schick B.
Mesenchymal-endothelial transition in juvenile angiofibroma?
Acta Otolaryngol. 2015 Sep;135(9):955-61.

Laschke MW, Augustin VA, Sahin F, Anschütz D, Metzger W, Scheuer C, Bischoff M, Aktas C, Menger MD

Surface modification by plasma etching impairs early vascularization and tissue incorporation of porous polyethylene (Medpor® ) implants.

J Biomed Mater Res B Appl Biomater. 2015 Sep 10. [Epub ahead of print]


Laschke MW, Kleer S, Scheuer C, Eglin D, Alini M, Menger MD.
Pre-cultivation of adipose tissue-derived microvascular fragments in porous scaffolds does not improve their in vivo vascularisation potential.
Eur Cell Mater. 2015 Mar 20;29:190-200;


Laschke MW, Menger MD

Adipose tissue-derived microvascular fragments: natural vascularization units for regenerative medicine.

Trends Biotechnol. 2015 Aug;33(8):442-8.


Liu X, Hao W, Qin Y, Decker Y, Wang X, Burkart M, Schötz K, Menger MD, Fassbender K, Liu Y.

Long-term treatment with Ginkgo biloba extract EGb 761 improves symptoms and pathology in a transgenic mouse model of Alzheimer's disease.

Brain Behav Immun. 2015 Jan 28. pii: S0889-1591(15)00014-8.


Moussavian MR, Laschke MW, Schlachtenberger 2, von HeesenM, Wagner M, Glanemann M, Menger MD.

Perigraft vascularization and incorporation of implanted Dacron prostheses are affected by rifampicin coating.

J Vasc Surg. 2015 Nov 19. pii: S0741-5214(15)01979-5.

Saar M, Körbel C, Linxweiler J, Jung V, Kamradt J, Hasenfus A, Stöckle M, Unteregger G, Menger MD.

Orthotopictumorgrafts in nudemice: A newmethod to studyhumanprostatecancer.

Prostate. 2015 Oct;75(14):1526-37.


Schaefer N, Kettner M, Laschke MW, Schlote J, Peters B, Bregel D, Menger MD, Maurer HH, Ewald AH, Schmidt PH.
Simultaneous LC-MS/MS determination of JWH-210, RCS-4, ∆(9)-tetrahydrocannabinol, and their main metabolites in pig and human serum, whole blood, and urine for comparing pharmacokinetic data.
Anal Bioanal Chem. 2015 May;407(13):3775-86.


Schrenk S, Schuster A, Klotz M, Schleser F, Lake J, Heuckeroth RO, Kim YJ, Laschke MW, Menger MD, Schäfer KH.

Vascular and neural stem cells in the gut: do they need each other?

Histochem Cell Biol. 2015 Apr;143(4):397-410.


Schuld J., Richter S., Eisele R.M., Von Heesen M., Roller J., Glanemann M.
Anal sphincter function after total mesorectal excision is comparable to that of healthy subjects: results of a matched pair analysis.
Minerva Chir. 2015 Jun;70(3):167-73.

Sperling J, Ziemann C, Gittler A, Benz-Weißer A, Menger MD, Kollmar O.
Tumour growth of colorectal rat liver metastases is inhibited by hepatic arterial infusion of the mTOR-inhibitor temsirolimus after portal branch ligation.
Clin Exp Metastasis. 2015 Apr;32(4):313-21.

Strowitzki MJ, Moussavian MR, Keppler U, Schilling MK, Menger MD, von Heesen M.

Isoflurane does not Protect from Brain Death-Associated Aggravation of Cold Hepatic Ischemia-Reperfusion Injury.

Ann Transplant. 2015 Jan 19;20:36-43


von Heesen M, Dold S, Müller S, Scheuer C, Kollmar O, Schilling MK, Menger MD, Moussavian MR
Cilostazol improves hepatic blood perfusion, microcirculation and liver regeneration after major hepatectomy in rats.
Liver Transpl. 2015 Jun;21(6):792-800.


von Heesen M, Müller S, Keppler U, Strowitzki MJ, Scheuer C, Schilling MK, Menger MD, Moussavian MR.

Preconditioning by cilostazol protects against cold hepatic ischemia-reperfusion injury.
Ann Transplant. 2015 Mar 26;20:160-8.


Voss M, Wolf L, Kamyschnikow A, Wonnenberg B, Honecker A, Herr C, Lepper PM, Wegmann M, Menger MD, Bals R, Beisswenger C.

IL-17A contributes to maintenance of pulmonary homeostasis in a murine model of cigarette smoke-induced emphysema.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L188-95. 


Wittig C, Scheuer C, Parakenings J, Menger MD, Laschke MW.

Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling.

PLoS One. 2015 Jul 8;10(7):e0131946. .