Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Leitung: Prof. Dr. med. Michael D. Menger
Publikationen 2018


Ampofo E, Schmitt BM, Menger MD, Laschke MW.

Targeting the microcirculation by indole-3-carbinol and its main derivate 3,3,'-diindolylmethane: Effects on angiogenesis, thrombosis and inflammation.

Mini Rev Med Chem. 2018;18:962-68.


Bächer C, Kihm A, Schrack L, Kaestner L, Laschke MW, Wagner C, Gekle S.

Antimargination of microparticles and platelets in the vicinity of branching vessels.

Biophys J. 2018;115:411-25.


Belkacemi A, Hui X, Wardas B, Laschke MW, Wissenbach U, Menger MD, Lipp P, Beck A, Flockerzi V.

IP3 receptor-dependent cytoplasmic Ca2+ signals are tightly controlled by Cavβ3.

Cell Rep. 2018;22:1339-49.


Cucchiarini M, Asen AK, Goebel L, Venkatesan JK, Schmitt G, Zurakowski D, Menger MD, Laschke MW, Madry H.

Effects of TGF-β overexpression via rAAV gene transfer on the early repair processes in an osteochondral defect model in minipigs.

Am J Sports Med. 2018;46:1987-96.


Decker Y, Müller A, Németh E, Schulz-Schaeffer WJ, Fatar M, Menger MD, Liu Y, Fassbender K.

Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains.

Brain Struct Funct. 2018;223:1001-15.


Frueh FS, Später T, Körbel C, Scheuer C, Simson AC, Lindenblatt N, Giovanoli P, Menger MD, Laschke MW.

Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting.

Sci Rep. 2018;8:10977.


Histing T, Bremer P, Rollmann MF, Herath S, Klein M, Pohlemann T, Menger MD, Fritz T.

A minimally invasive model to analyze endochondral fracture healing in mice under standardized biomechanical conditions.

J Vis Exp. 2018;22;133.


Karschnia P, Scheuer C, Heß A, Später T, Menger MD, Laschke MW.

Erythropoietin promotes network formation of transplanted adipose tissue-derived microvascular fragments.

Eur Cell Mater. 2018;35:268-80.


Körbel C, Gerstner MD, Menger MD, Laschke MW.

Notch signaling controls sprouting angiogenesis of endometriotic lesions.

Angiogenesis. 2018;21:37-46.


Körbel C, Linxweiler M, Bochen F, Wemmert S, Schick B, Meyer M, Maurer H, Menger MD, Zimmermann R, Greiner M.

Treatment of SEC62 over-expressing tumors by thapsigargin and trifluoperazine.

Biomol Concepts. 2018;9:53-63.


Laschke MW, Karschnia P, Scheuer C, Heß A, Metzger W, Menger MD.

Effects of cryopreservation on adipose tissue-derived microvascular fragments.

J Tissue Eng Regen Med. 2018;12:1020-30.


Laschke MW, Menger MD.

Basic mechanisms of vascularization in endometriosis and their clinical implications.

Hum Reprod Update. 2018;24:207-24.


Laschke MW, Menger MD.

Reply: Vascularization in endometriosis and its clinical applications.

Hum Reprod Update. 2018;24:638.


Laschke MW, Vollmar B.

Vascularization, regeneration and tissue engineering.

Eur Surg Res. 2018;59:230-1.


Linxweiler J, Körbel C, Müller A, Hammer M, Veith C, Bohle RM, Stöckle M, Junker K, Menger MD, Saar M.

A novel mouse model of human prostate cancer to study intraprostatic tumor growth and the development of lymph node metastases.

Prostate. 2018;78:664-75.


Orth M, Altmeyer MAB, Scheuer C, Braun BJ, Holstein JH, Eglin D, D'Este M, Histing T, Laschke MW, Pohlemann T, Menger MD.

Effects of locally applied adipose tissue-derived microvascular fragments by thermoresponsive hydrogel on bone healing.

Acta Biomater. 2018;77:201-11.


Orth M, Shadmanov T, Scheuer C, Braun BJ, Fritz T, Holstein JH, Histing T, Laschke MW, Pohlemann T, Menger MD.

Marble-derived microcalcite improves bone healing in mice osteotomy.

Biomed Mater. 2018;14:025001.


Qin Y, Zhang Y, Tomic I, Hao W, Menger MD, Liu C, Fassbender K, Liu Y.

Ginkgo biloba extract EGb 761 and its specific components elicit protective protein clearance through the autophagy-lysosomal pathway in tau-transgenic mice and cultured neurons.

J Alzheimers Dis. 2018;65:243-63.


Rudzitis-Auth J, Nickels RM, Menger MD, Laschke MW.

Inhibition of cyclooxygenase-2 suppresses the recruitment of endothelial progenitor cells in the microvasculature of endometriotic lesions.

Am J Pathol. 2018;188:450-60.


Schaefer N, Kroll AK, Laschke MW, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Development of an in-vitro drug delivery efficiency test for a pulmonary toxicokinetic pig study.

Curr Drug Deliv. 2018;15:1167-71.


Schaefer N, Wojtyniak JG, Kroell AK, Koerbel C, Laschke MW, Lehr T, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?

Biochem Pharmacol. 2018;155:403-18.


Schmitt BM, Laschke MW, Rössler OG, Huang W, Scheller A, Menger MD, Ampofo E.

Nerve/glial antigen (NG) 2 is a crucial regulator of intercellular adhesion molecule (ICAM)-1 expression.

Biochim Biophys Acta Mol Cell Res. 2018;1865:57-66.


Siebenbuerger L, Hernandez-Olmos V, Abdelsamie AS, Frotscher M, van Koppen CJ, Marchais-Oberwinkler S, Scheuer C, Laschke MW, Menger MD, Boerger C, Hartmann RW.

Highly potent 17β-HSD2 inhibitors with a promising pharmacokinetic profile for targeted osteoporosis therapy.

J Med Chem. 2018;61:10724-10738.


Simgen A, Tomori T, Mühl-Benninghaus R, Bomberg H, Yilmaz U, Körner H, Laschke MW, Menger MD, Reith W.

Retrieval of migrated volume coils using different clot retrievers in a porcine model.

Clin Neuroradiol. 2018;28:593-600.


Später T, Frueh FS, Karschnia P, Menger MD, Laschke MW.

Enoxaparin does not affect network formation of adipose tissue-derived microvascular fragments.

Wound Repair Regen. 2018;26:36-45.


Später T, Frueh FS, Metzger W, Menger MD, Laschke MW.

In vivo biocompatibility, vascularization, and incorporation of Integra® dermal regenerative template and flowable wound matrix.

J Biomed Mater Res B Appl Biomater. 2018;106:52-60.


Später T, Frueh FS, Nickels RM, Menger MD, Laschke MW.

Prevascularization of collagen-glycosaminoglycan scaffolds: stromal vascular fraction versus adipose tissue-derived microvascular fragments.

J Biol Eng. 2018;12:24.


Später T, Müller I, Eichler H, Menger MD, Laschke MW, Ampofo E.

Dual inhibition of PI3K and mTOR by VS-5584 suppresses thrombus formation.

Platelets. 2018;29:277-87.