Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Jahrgang 2016
Leitung: Prof. Dr. Michael Böhm

Jahrgang 2016

  • Custodis F, Roggenbuck U, Lehmann N, Moebus S, Laufs U, Mahabadi AA, Heusch G, Mann K, Jöckel KH, Erbel R, Böhm M, Möhlenkamp S (2016)
    Resting heart rate is an independent predictor of all-cause mortality in the middle aged general population.
    Clin Res Cardiol 105: 601-612

  • Greulich S, Kindermann I, Schumm J, Perne A, Birkmeier S, Grün S, Ong P, Schäufele T, Klingel K, Schneider S, Kandolf R, Böhm M, Sechtem U, Mahrholdt H (2016)
    Predictors of outcome in patients with Parvovirus B19 positive endomyocardial biopsy.
    Clin Res Cardiol 105: 37-52

  • Rogacev K, Heine GH, Silbernagel G, Kleber ME, Seiler S, Emrich I, Lennartz S, Werner C, Zawada AM, Fliser D, Böhm M, März W, Scharnagl H, Laufs U (2016)
    PCSK9 plasma concentrations are independent of GFR and do not predict cardiovascular events in patients with decreased GFR.
    PLoS ONE 11: e0146920

  • Bunz M, Lenski D, Wedegärtner S, Ukena C, Karbach J, Böhm M, Kindermann I (2016)
    Heart-focused anxiety in patients with chronic heart failure before implantation of an implantable cardioverter defibrillator: baseline findings of the Anxiety-CHF Study.
    Clin Res Cardiol 105: 216-224

  • Donazzan L, Mahfoud F, Ewen S, Ukena C, Cremers B, Kirsch CM, Hellwig D, Eweiwi T, Ezziddin S, Esler M, Böhm M (2016)
    Effects of catheter-based renal denervation on cardiac sympathetic activity and innervation in patients with resistant hypertension.
    Clin Res Cardiol 105:364-371

  • Clever YP, Peters D, Calisse J, Bettink S, Berg MC, Sperling C, Stoever M, Cremers B, Kelsch B, Böhm M, Speck U, Scheller B (2016)
    Novel sirolimus–coated balloon catheter - in vivo evaluation in a porcine coronary model.
    Circ Cardiovasc Interv 9: e003543

  • Kotecha D, Manzano L, Krum H, Rosano G, Holmes J, Altman DG, Collins PD, Packer M, Wikstrand J, Coats AJS, Cleland JFG, Kirchhof P, von Lueder TG, Rigby AS, Andersson B, Lip GYH, van Veldhuisen DJ, Shibata MC, Wedel H, Böhm M, Flather MD on behalf oft he Beta-Blockers in Heart Failure Collaborative Group (2016)
    Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis
    BMJ 353: i1855

  • Pinto YM, Elliott PM, Arbustini E, Adler Y, Anastasakis A, Böhm M, Duboc D, Gimeno J, de Groote P, Imazio M, Heymans S, Klingel K, Komajda M, Limongelli G, Linhart A, Mogensen J, Moon J, Pieper PG, Seferovic PM, Schueler S, Zamorano JL, Caforio ALP, Charron P (2016)
    Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases.
    Eur Heart J 37: 1850-1858

  • Haghikia A, Tongers J, Berliner D, König T, Schäfer A, Brehm M, Böhm M, Hilfiker-Kleiner D, Bauersachs J (2016)
    Early ivabradine treatment in patients with acute peripartum cardiomyopathy: Subanalysis of the German PPCM registry.
    Int J Cardiol 216: 165-167

  • Ghadri JR, Sarcon A, Diekmann J, Bataiosu DR, Cammann VL, Stjepan Jurisic S, Napp LC, Jaguszewski M, Scherff F, Brugger P, Jäncke L, Seifert B, Bax JJ, Ruschitzka F, Lüscher TF, Templin C (2016)
    InterTAK Co-investigators: Schwyzer M, Franke J, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KEJ, Fijalkowski M, Rynkiewicz A, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Prasad A
    Happy heart syndrome: role of positive emotional stress in takotsubo syndrome.
    Eur Heart J [doi: 10.1093/eurheartj/ehv757]

  • Filippatos G, Anker SD, Böhm M, Gheorghiade M, Køber L, Krum H, Maggioni AP, Ponikowski P, Voors AA, Zannad F, Kim SY, Nowack C, Palombo G, Kolkhof P, Kimmeskamp-Kirschbaum N, Pieper A, Pitt B (2016)
    A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease.
    Eur Heart J 37: 2105-2114

  • Linz D, Hohl M, Khoshkish S, Mahfoud F, Ukena C, Neuberger HR, Wirth K Böhm M (2016)
    Low-level but not high-level baroreceptor stimulation inhibits atrial fibrillation in a pig model of sleep apnea.
    J Cardiovasc Electrophysiol 27: 1086-1092

  • Komajda M, Tavazzi L, Swedberg K, Böhm M, Borer JS, Moyne A, Ford I, on behalf oft he SHIFT Investigators (2016)
    Chronic exposure to ivabradine reduces readmissions in the vulnerable phase after hospitalization for worsening systolic heart failure: a post-hoc analysis of SHIFT.
    Eur J Heart Fail 18: 1182-1189

  • Schmieder R, Bramlage P, Haller H, Ruilope LM, Böhm M fort he ROADMAP Investigators (2016)
    the effect of resting heart rate on the new onset of microalbuminuria in patients with type 2 diabetes.
    Medicine 95: e3122

  • Linz D, Hohl M, Dhein S, Ruf S, Reil JC, Kabiri M, Wohlfart P, Verheule S, Böhm M, Sadowski T, Schotten U (2016)
    Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in zucker diabetic fatty rats.
    Cardiovasc Res 110: 371-380

  • Linz B, Hohl M, Reil JC, Böhm M Linz D (2016)
    Inhibition of NHE3-mediated sodium absorption in the gut reduced cardiac end-organ damage without deteriorating renal function in obese spontaneously hypertensive rats.
    J Cardiovasc Pharmacol 67, 225-231

  • Holzhey D, Mohr FW, Walther T, Möllmann H, Beckmann A, Kötting J, Figulla HR, Cremer J, Kuck KH, Lange R, Sack S, Schuler G, Beyersdorf F, Böhm M, Heusch G, Meinertz T, Neumann T, Papoutsis K, Schneider S, Welz A, Hamm CW (2016)
    Current results of surgical valve replacement: Insights from the German Valve Registry.
    Ann Thorac Surg 101: 658-666

  • Böhm M, Lloyd SM, Ford I, Borer JS, Ewen S, Laufs U, Mahfoud F, Lopez-Sendon J, Ponikowski P, Tavazzi L, Swedberg K, Komajda M (2016)
    Non-adherence to ivabradine and placebo and outcomes in chronic heart failure: an analysis from SHIFT.
    Eur J Heart Fail 18: 672-683

  • Angermann CE, Gelbrich G, Störk S, Gunold H, Edelman F, Wachter R, Schunkert H, Graf T, Kindermann I, Haass M, Blankenberg S, Pankuweit S, Prettin C, Gottwik M, Böhm M, Faller H, Deckert J, Ertl G fort he MOOD-HF Study Investigators and Commitee Members (2016)
    Effect of escitalopram on all-cause mortality and hospitalization in patients with heart failure and depression: The MOOD-HF Randomized Clinical Trial.
    JAMA 315: 2683-2693

  • Mahfoud F, Moon LB, Pipenhagen CA, Jensen JA, Pathak A, Papademetriou V, Ewen S, Linz D, Böhm M (2016)
    Catheter-based radio-frequency renal nerve denervation lowers blood pressure in obese hypertensive swine model.
    J Hypertens 34: 1854-1862

  • Fuernau G, Fengler K, Desch S, Eitel I, Neumann FJ, Olbrich HG, de Waha A, de Waha S, Richardt G, Hennersdorf M, Empen K, Hambrecht R, Jung C, Böhm M, Pöss J, Strasser RH, Schneider S, Ouarrak T, Schuler G, Werdan K, Zeymer U, Thile H (2016)
    Culprit lesion location and outcome in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial.
    Clin Res Cardiol 105: 1030-1041

  • Linz D, Denner A, Illing S, Hohl M, Ukena C, Mahfoud F, Ewen S, Reil JC, Wirth K, Böhm M (2016)
    Impact of obstructive and central apneas on ventricular repolarisation: lessons learned from studies in man and pigs.
    Clin Res Cardiol 105: 639-647

  • Kratz MT, Schirmer SH, Baumhäkel M, Böhm M (2016)
    Improvement of endothelial function in a murine model of mild cholesterol-induced atherosclerosis by mineralocorticoid antagonism.
    Atherosclerosis 251: 291-298

  • De Jager RL, Sanders MF, Bots ML, Lobo MD, Ewen S, Beeftink MMA, Böhm M, Daemen J, Dörr O, Hering D, Mahfoud F, Nef H, Ott C, Saxena M, Schmieder RE, Schlaich MP, Spiering W, Tonino PAL, Verloop WL, Vink EE, Vonken EJ, Voskuil M, Worthley SG, Blankestijn PJ (2016)
    Renal denervation in hypertensive patients not on blood pressure lowering drugs.
    Clin Res Cardiol 105: 755-762

  • Mahfoud F, Bakris G, Bhatt DL, Esler M, Ewen S, Fahy M, Kandzari D, Kario K, Mancia G, Weber M, Böhm M (2016)
    Reduced blood pressure-lowering effect of catheter-based renal denervation in patients with isolated systolic hypertension: data from SYMPLICITY HTN-3 and the Global SYMPLICITY Registry.
    Eur Heart J [doi: 10.1093/eurheartj/ehw325]

  • Borer JS, Swedberg K, Komajda M, Ford I, Tavazzi L, Böhm M, Depre C, Wu Y, Maya J, Dominion F (2016)
    Efficacy profile of ivabradine in patients with heart failure plus angina pectoris.
    Cardiology 136: 138-144

  • Ewen S, Ukena C, Lüscher TF, Bergmann M, Blankestijn PJ, Blessing E, Cremers B, Dörr O, Hering D, Kaiser L, Nef H, Noory E, Schlaich M, Sharif F, Sudano I, Vogel B, Voskuil M, Zeller T, Tzafriri AR, Edelman ER, Lauder L, Scheller B, Böhm M, Mahfoud F (2016)
    Anatomical and procedural determinants of catheter-based renal denervation.
    Cardiovasc Revasc Med 17: 474-479

  • Ott C, Mahfoud F, Schmid A, Ewen S, Toennes SW, Meyer MR, Helfer AG, Maurer HH, Ditting T, Veelken R, Zivanovic I, Uder M, Böhm M, Schmieder RE (2016)
    The effect of renal denervation in moderate treatment-resistant hypertension with confirmed medication adherence.
    J Hypertens 34: 2475-2479

  • Lavall D, Reil JC, Segura Schmitz L, Mehrer M, Schirmer SH, Böhm M, Laufs U (2016)
    Early hemodynamic improvement after percutaneous mitral valve repair evaluated by noninvasive pressure-volume analysis.
    J Am Soc Echocardiogr 29: 888-898

  • Linz D, Hohl M, Khoshkish S, Mahfoud F, Ukena C, Neuberger HR, Wirth K, Böhm M (2016)
    Low-level but not high-level baroreceptor stimulation inhibits atrial fibrillation in a pig model of sleep apnea.
    J Cardiovasc Electrophysiol 27: 1086-1092

  • Linz D, Hohl M, Dhein S, Ruf S, Reil JC, Kabiri M, Wohlfart P, Verheule S, Böhm M, Sadowski T, Schotten U (2016)
    Cathepsin a mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in zucker diabetic fatty rats.
    Cardiovasc Res 110; 371-380

  • Böhm M, Robertson M, Borer J, Ford I, Komajda M, Mahfoud F, Ewen S, Swedberg K, Tavazzi L (2016)
    Effect of visit-to-visit variation in heart rate and systolic blood pressure on outcomes in chronic systolic heart failure: Results from the systolic heart failure treatment with the If Inhibitor Ivabradine (SHIFT) trial.
    J Am Heart Assoc 5: e002160

  • Ukena C, Mahfoud F, Ewen S, Bollmann A, Hindricks G, Hoffmann BA, Linz D, Musat D, Pavlicek V, Scholz E, Thomas D, Willems S, Böhm M, Steinberg JS (2016)
    Renal denervation for treatment of ventricular arrhythmias: data from an International Multicenter Registry.
    Clin Res Cardiol 105: 873-879

  • Linz D, Mancia G, Mahfoud F, Narkiewicz K, Ruilope L, Schlaich M, Kindermann I, Schmieder RE, Ewen S, Williams B, Böhm M on behalf of the Global SYMPLICITY Registry Investigators (2016)
    Renal artery denervation for treatment of patients with self-reported obstructive sleep apnea and resistant hypertension: results from the Global SYMPLICITY Registry.
    J Hypertens 35: 148-153

  • Schwarz V, Bachelier K, Schirmer SH, Werner C, Laufs U, Böhm M (2016)
    Red wine prevents the acute negative vascular effects of smoking.
    Am J Med 130: 95-100

  • Custodis F, Rohlehr F, Wachter A, Böhm M, Schulz M, Laufs U (2016)
    Medication knowledge of patients hospitalized for heart failure at admission and after discharge.
    Patient Preference and Adherence 10: 2333-2339

  • Ghadri JR, Cammann VL, Jurisic S, Seifert B, Napp LC, Diekmann J, Bataiosu DR, D’Ascenzo F, Ding KJ, Sarcon A, Kazemian E, Birri T, Ruschitzka F, Lüscher TF, Templin C (2016)
    A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry.
    Eur J Heart Fail [doi: 10.1002/ejhf.683]

  • Kansal AR, Krotneva S, Tafazzoli A, Patel HK, Borer JS, Böhm M, Komajda M, Maya J, Tavazzi L, Ford I, Kielhorn A (2016)
    Financial impact of ivabradine on reducing heart failure penalties under the Hospital Readmission Reduction Program.
    Cur Med Res Opin 33: 185-191

  • Lange R, Beckmann A, Neumann T, Krane M, Deutsch MA, Landwehr S, Kötting J, Welz A, Zahn R, Cremer J, Figulla HR, Schuler G, Holzhey DM, Kathrin Funkat AK, Heusch G, Sack S, Pasic M, Meinertz T, Thomas Walther T, Kuck KH, Beyersdorf F, Böhm M, Möllmann H, Hamm CW, Mohr FW for the GARY Executive Board (2016)
    Quality of life after transcatheter aortic valve replacement.
    J Am Coll Cardiol Intv 9: 2541-2554

  • Greene SJ, Fonarow GC, Solomon SD, Subacius HP, Ambrosy AP, Vaduganthan M, Maggioni AP, Böhm M, Lewis EF, Zannad F, Gheorghiade M for the ASTRONAUT Investigators and Coordinators (2016)
    Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial.
    Eur J Heart Fail 19: 552-562

  • Ghadri JR, Sarcon A, Diekmann J, Bataiosu DR, Cammann VL, Jurisic S, Napp LC, Jaguszewski M, Scherff F, Brugger P, Jäncke L, Seifert B, Bax JJ, Ruschitzka F, Lüscher TF, Templin C, Schwyzer M, Franke J, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KE, Fijalkowski M, Rynkiewicz A, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Prasad A for the InterTAK Co-investigators (2016)
    Happy heart syndrome: role of positive emotional stress in takotsubo syndrome.
    Eur Heart J 37: 2823-2829

  • Linz D, Hohl M, Vollmar J, Ukena C, Mahfoud F, Böhm M (2016)
    Atrial fibrillation and gastroesophageal reflux disease: the cardiogastric interaction.
    Europace 19: 16-20

  • Mahfoud F, Bakris G, Bhatt DL, Esler M, Ewen S, Fahy M, Kandzari D, Kario K, Mancia G, Weber M, Böhm M (2016)
    Reduced blood pressure-lowering effect of catheter-based renal denervation in patients with isolated systolic hypertension: data from SYMPLICITY HTN-3 and the Global SYMPLICITY Registry.
    Eur Heart J 38: 93-100

  • Ott C, Kistner I, Schmid A, Friedrich S, Ditting T, Veelken R, Mahfoud F, Böhm M, Uder M, Schmieder R (2016)
    OS 28-03 secretory capacity of pancreatic beta cells is enhanced 6 months after renal denervation in treatment resistant hypertensive patients.
    J Hypertens 34: e251

  • Scheller B, Fontaine T, Mangner N, Hoffmann S, Bonaventura K, Clever YP, Chamie D, Costa R, Gershony G, Kelsch B, Kutschera M, Généreux P, Cremers B, Böhm M, Speck U, Abizaid A (2016)
    A novel drug-coated scoring balloon for the treatment of coronary in-stent restenosis: Results from the multi-center randomized controlled PATENT-C first in human trial.
    Catheter Cardiovasc Interv 88: 51-59

  • Reil JC, Tauchnitz M, Tian Q, Hohl M, Linz D, Oberhofer M, Kaestner L, Reil GH, Thiele H, Steendijk P, Böhm M, Neuberger HR, Lipp P (2016)
    Hyperaldosteronism induces left atrial systolic and diastolic dysfunction.
    Am J Physiol Heart Circ Physiol 311: H1014-H1023

  • Linicus Y, Kindermann I, Cremers B, Maack C, Schirmer S, Böhm M (2016)
    Vena cava compression syndrome in patients with obesity presenting with edema and thrombosis.
    Obesity 24: 1648-1652

  • Kandzari DE, Kario K, Mahfoud F, Cohen SA, Pilcher G, Pocock S, Townsend R, Weber MA, Böhm M (2016)
    The SPYRAL HTN Global Clinical Trial Program: Rationale and design for studies of renal denervation in the absence (SPYRAL HTN OFF-MED) and presence (SPYRAL HTN ON-MED)
    of antihypertensive medications.
    Am Heart J 171: 82-91

  • Hohl M, Linz D, Fries P, Müller A, Stroeder J, Urban D, Speer T, Geisel J, Hummel B, Laufs U, Schirmer SH, Böhm M, Mahfoud F (2016)
    Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats.
    J Transl Med 14: 167

  • Haghikia A, Tongers J, Berliner D, König T, Schäfer A, Brehm M, Böhm M, Hilfiker-Kleiner D, Bauersachs J (2016)
    Early ivabradine treatment in patients with acute peripartum cardiomyopathy: Subanalysis of the German PPCM registry.
    Int J Cardiol 216: 165-167

  • Borer JS, Kansal AR, Dorman ED, Krotneva S, Zheng Y, Patel HK, Tavazzi L, Komajda M, Ford I, Böhm M, Kielhorn A (2016)
    Budget Impact of Adding Ivabradine to Standard of Care in Patients with Chronic Systolic Heart Failure in the United States.
    J Manag Care Spec Pharm 22: 1064-1071

  • Böhm M, Ukena C, Ewen S, Linz D, Zivanovic I, Hoppe U, Narkiewicz K, Ruilope L, Schlaich M, Negoita M, Schmieder R, Williams B, Zeymer U, Zirlik A, Mancia G, Mahfoud F, Global SYMPLICITY Registry Investigators (2016)
    Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes from the global SYMPLICITY registry.
    J Hypertens 34: 2480-2486

  • Böhm M, Drexler H, Oswald H, Rybak K, Bosch R, Butter C, Klein G, Gerritse B, Monteiro J, Israel C, Bimmel D, Käab S, Huegl B, Brachmann J, OptiLink HF Study Investigators (2016)
    Fluid status telemedicine alerts for heart failure: a randomized controlled trial.
    Eur Heart J 37: 3154-3163