Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Jahrgang 2010
Leitung: Prof. Dr. Michael Böhm

Jahrgang 2010

  • Ruilope LM, Dukat A, Böhm M, Lacourcière Y, Gong J, Lefkowitz M (2010)
    Blood pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomized, double-blind, placebo-controlled, active comparator study.
    Lancet 375: 1255-1266

  • Adam O, Lavall D, Theobald K, Hohl M, Grube M, Ameling S, Sussman MA, Rosenkranz S, Kroemer HK, Schäfers HJ, Böhm M, Laufs U (2010)
    Rac1-Induced connective tissue growth factor regulates connexin 43 and N-Cadherin expression in Atrial fibrillation.
    J Am Coll Cardiol 55: 469-480

  • Kamp O, Metra M, De Keulenaer GW, Pieske B, Conraads V, Zamorano J, Huysse L, Vardas PE, Böhm M, Del Cas L (2010)
    Effect of the long-term administration of nebivolol on clinical symptoms, exercise capacity and left ventricular function in patients with heart failure and preserved left ventricular ejection fraction: background, aims and design of the ELANDD study.
    Clin Res Cardiol 99: 75-82

  • Böhm M, Baumhäkel M, Koon T, Sleight P, Probstfield J, Gao P, Mann JF, Diaz R, Dagenais GR, Jennings GLR, Liu L, Jansky P, Yusuf S and for the ONTARGET/TRANSCEND Erectile Dysfunction Substudy Investigators (2010)
    Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both. The OngoingTelmisartan Alone an in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (ONTARGET/TRANSCEND) trials.
    Circulation 121: 1439-1446

  • Kohlhaas M, Liu T, Knopp A, Zeller T, Ong MF, Böhm M, O’Rourke B,
    Maack C (2010)
    Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes.
    Circulation 121: 1606-1613

  • Reil JC, Hohl M, Oberhofer M, Kazakov A, Kaestner L, Müller P, Adam O, Maack C, Lipp P, Mewis C, Allessie M, Laufs U, Böhm M, Neuberger HP (2010)
    Cardiac Rac1 overexpression in mice creates a substrate for atrial arrhythmias characterized by structural remodelling.
    Cardiovasc Res 87: 485-493

  • Baumhäkel M, Custodis F, Schlimmer N, Laufs U, Böhm M (2010)
    Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice.
    Atherosclerosis 212: 55-62

  • Schneider MP, Hua TA, Böhm M, Wachtell K, Kjeldsen SE, Schmieder RE (2010)
    Prevention of Atrial Fibrillation by Renin-Angiotensin System Inhibition.
    J Am Coll Cardiol 55: 2299-2307

  • Thoenes M, Neuberger HR, Volpe M, Khan BV, Kirch W, Böhm M (2010)
    Antihypertensive drug therapy and blood pressure control in men and women: an international perspective.
    J Human Hypertens 24: 336-344

  • Inglis SC, McMurray JJV, Böhm M, Schaufelberger M, van Veldhuisen DJ, Lindberg M, Dunselman P, Hjalmarson Å, Kjekshus J, Waagstein F, Wedel H, Wikstrand J on behalf of the CORONA Study Group (2010)
    Intermittent claudication as a predictor of outcome in patients with ischemic systolic heart failure: analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure trial (CORONA)
    Eur J Heart Fail 12: 698-705

  • Bettink SI, Werner C, Chen CH, Müller P, Schirmer SH, Walenta KL, Böhm M Laufs U, Friedrich EB (2010)
    Integrin-linked kinase is a central mediator in angiotensin II type 1- and chemokine receptor CXCR4 signaling in myocardial hypertrophy.
    Biochem Biophys Res Comm 397: 208-213

  • Yilmaz A, Kindermann I, Kindermann M, Mahfoud F, Ukena C, Athanasiadis A, Hill S, Mahrholdt H, Voehringer M, Schieber M, Klingel K, Kandolf R, Böhm M, Sechtem U (2010)
    Comparative evaluation of left and right ventricular endomyocardial biopsy. Differences in complication rate and diagnostic performance.
    Circulation 122: 900-909

  • Tebbe U, Bramlage P, Lüders S, Cuneo A, Sistig P, de Haan F, Schmieder R, Böhm M, Paar WP, Schrader J (2010)
    Follow-up of cardiovascular risk markers in hypertensive patients treated with irbesartan: results of the i-SEARCH Plus registry
    J Clin Hypertens 12: 909-916

  • Swedberg K, Komajda M, Böhm M, Borer JS, Ford I, Dubost-Brama A, Lerebours G, Tavazzi L on behalf of the SHIFT Investigators (2010)
    Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study.
    Lancet 376: 875-885

  • Böhm M, Swedberg K, Komajda M, Borer JS, Ford I, Dubost-Brama A, Tavazzi L, on behalf of the SHIFT Investigators (2010)
    Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial.
    Lancet 376: 886-894

  • Pöss J, Werner C, Lorenz D, Gensch C, Böhm M, Laufs U (2010)
    The renin inhibitor aliskiren upregulates pro-angiogenic cells and reduces atherogenesis in mice.
    Basic Res Cardiol 105: 725-735

  • McMurray JJV, Dunselman P, Wedel H, Cleland JGF, Lindberg M, Hjalmarson Å, Kjekshus J, Waagstein F, Apetrei E, Barrios V, Böhm M, Kamenský G, Komajda M, Mareev V, Wikstrand J on behalf of the CORONA Study Group (2010)
    Coenzyme Q10, Rosuvastatin, and Clinical Outcomes in Heart Failure
    J Am Coll Cardiol 56: 1196-1204

  • Böhm M, Laufs U, Pfreundschuh M (2010)
    Angiotensin-receptor blockade, cancer, and concerns. (letter)
    Lancet Oncology 11: 818-819

  • Wagner DR, Roesch N, Harpes P, Körtke H, Plumer P, Saberin A, Chakoutio V, Oundjede D, Delagardelle C, Beissel J, Gilson G, Kindermann I, Böhm M (2010)
    Relationship between pulse transit time and blood pressure is impaired in patients with chronic heart failure.
    Clin Res Cardiol 99: 657-664

  • Buob A, Winter H, Kindermann M, Becker G, Möller JC, Oertel WH, Böhm M (2010)
    Parasympathetic but not sympathetic cardiac dysfunction at early stages of Parkinson’s disease.
    Clin Res Cardiol 99: 701-706

  • Ukena C, Mahfoud F, Kindermann M, Gräber S, Kindermann I, Schneider M, Schmieder R, Bramlage P, Volpe M, Thoenes M, Böhm M (2010)
    Smoking is associated with a high prevalence of microalbuminuria in hypertensive high-risk patients: data from I-SEARCH
    Clin Res Cardiol 99: 825-832

  • Walenta KLH, Bettink S, Böhm M, Friedrich EB (2010)
    Differential chemokine receptor expression regulates functional specialization of endothelial progenitor cell subpopulations.
    Basic Res Cardiol 106: 299-305

  • Reiff T, Böckler D, Böhm M, Brückmann H, Debus ES, Eckstein HH, Fiehler J, Fraedrich G, Hennerici M, Jansen O, Lang W, Mansmann U, Mathias K, Mudra H, Ringelstein EB, Ringleb PA, Schmidli J, Stingele R, Zahn R, Hacke W (2010)
    Ongoing Randomized Controlled Trials Comparing Interventional Methods and Optimal Medical Treatment in the Treatment of Asymptomatic Carotid Stenosis. (letter)
    Stroke 41: e605-e606

  • Koehler F, Winkler S, Schieber M, Sechtem U, Stangl K, Böhm M, Boll H, Kim SS, Koehler K, Lücke S, Honold M, Heinze P, Schweizer T, Braecklein M, Kirwan BA, Gelbrich G, Anker SD on behalf of the TIM-HF Investigators (2010)
    Telemedical Interventional Monitoring in Heart Failure (TIM-HF), a randomized, controlled intervention trial investigating the impact of telemedicine on mortality in ambulatory patients with heart failure: study design.
    Eur J Heart Fail 12: 1354-1362

  • Esler MD, Krum H, Sobotka PA, Schlaich MP, Schmieder RE, Böhm M on behalf of the Symplicity HTN-2 Investigators (2010)
    Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial.
    Lancet 376: 1903-1909