FET-PET in brain tumors
The amino acid tyrosine is a natural building block of protein metabolism. Tyrosine labeled with the radioactive isotope 18F (18F-FET (F-18- Ethyltyrosine)) has a high specificity in the identification of brain tumors and is used to distinguish them from healthy, inflammatory, irradiated/scarred brain tissue (e.g. as part of radiotherapy or surgery planning) and in particular for the early diagnosis of recurrences.
Preparation for the examination
No special preparation is necessary. For a successful examination you do not have to be fasting, but if possible you should eat only a light meal at least 2 hours before the examination. You may also take all your medications as usual.
Examination procedure
A low-level radioactive substance (fluorine-18 tyrosine) is injected into an arm vein before the examination. With this substance, amino acid metabolism of the brain is made visible. After the injection you need to rest for 15 minutes. During this time, the substance is completely absorbed and distributed in the brain. After this time, the images are obtained (duration approx. 25 min.), during which you should lie absolutely still.
Aftercare
There is no need to restrict yourself in any way after the examination and you can pursue your usual activities.
Side effects
No side effects are to be expected from the injection of the radioactive tracer itself.
Side effects can be caused by the administration of iodine-containing contrast medium within the scope of the possibly accompanying contrast medium-supported CT (intolerance reaction, hyperthyroidism, intensification of a pre-existing renal insufficiency). During the consultation with our physicians, please make sure to point out if you have experienced a contrast reaction in the past (reddening of the skin, itching, swelling, shortness of breath, etc.).
