Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Klinik für Innere Medizin II - Gastroenterologie und Endokrinologie
Kommissarischer Leiter der Klinik: Prof. Dr. med. Marcin Krawczyk
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2012

1.

Appenrodt B, Sauerbruch T.
Susceptibility to spontaneous bacterial peritonitis--are genetics the future?
Liver Int. 2012 Feb;32(2):177-8

2.

Casper M, Plotz G, Juengling B, Zeuzem S, Lammert F, Raedle J.
MUTYH hotspot mutations in unselected colonoscopy patients.
Colorectal Dis. 2012 May;14(5):e238-44.

3.

Gonzalez-Carmona MA, Sandhoff R, Tacke F, Vogt A, Weber S, Canbay AE, Rogler G, Sauerbruch T, Lammert F, Yildiz Y.
Beta-glucosidase 2 knockout mice with increased glucosylceramide show impaired liver regeneration.
Liver Int. 2012 Oct;32(9):1354-62

4.

Grotemeyer K, Kaiser R.
84-jährige Patientin mit Verdacht auf kardiale Dekompensation
Dtsch Med Wochenschr. 2012 Jul;137(27):1387.

5.

Grünhage F, Hochrath K, Krawczyk M, Höblinger A, Obermayer-Pietsch B, Geisel J, Trauner M, Sauerbruch T, Lammert F.
Common genetic variation in vitamin D metabolism is associated with liver stiffness.
Hepatology. 2012 Nov;56(5):1883-91.

6.

Hadem J, Tacke F, Bruns T, Langgartner J, Strnad P, Denk GU, Fikatas P, Manns MP, Hofmann WP, Gerken G, Grünhage F, Umgelter A, Trautwein C, Canbay A; Acute Liver Failure Study Group Germany.
Etiologies and outcomes of acute liver failure in Germany.
Clin Gastroenterol Hepatol. 2012 Jun;10(6):664-669.e2.

7.

Heyne K, Huwer J, Zimmer V, Pfreundschuh M, Ney JT, Assmann G.
Different apoptotic responses of RA synoviocytes depending on different genotypes of the mdm2 SNP T309G.
Apoptosis. 2012 Apr;17(4):424-7.

8.

Hochrath K, Krawczyk M, Goebel R, Langhirt M, Rathkolb B, Micklich K, Rozman J, Horsch M, Beckers J, Klingenspor M, Fuchs H, Gailus-Durner V, Wolf E, Acalovschi M, Volmer DA, Hrabe de Angelis M, Lammert F.
The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis.
FASEB J. 2012 Dec;26(12):5081-91.

9.

Jeanmonod P, Hubbuch M, Grünhage F, Meiser A, Rass K, Schilling MK, Kollmar O.
Graft-versus-host disease or toxic epidermal necrolysis: diagnostic dilemma after liver transplantation.
Transpl Infect Dis. 2012 Aug;14(4):422-6.

10.

Klein S, Klösel J, Schierwagen R, Körner C, Granzow M, Huss S, Mazar IG, Weber S, van den Ven PF, Pieper-Fürst U, Fürst DO, Nattermann J, Lammert F, Sauerbruch T, Trebicka J.
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats.
Lab Invest. 2012 Oct;92(10):1440-50.

11.

Krawczyk M, Zimmermann S, Vidacek D, Lammert F.
Intraperitoneal Catumaxomab Therapy in a Cirrhotic Patient with Malignant Ascites due to Urethelial Carcinoma: A Case Report.
Onkologie. 2012;35(10):592-4.

12.

Krawczyk M, Acalovschi M, Lammert F
Genetic study of FGF19 receptor variants in gallstone disease.
Hepatology. 2012 Dec;56(6):2424.

13.

Krawczyk M, Lütjohann D, Schirin-Sokhan R, Villarroel L, Nervi F, Pimentel F, Lammert F, Miquel JF.
Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease.
Hepatology. 2012 May;55(5):1507-17

14.

Krawczyk M, Grünhage F, Langhirt M, Bohle RM, Lammert F.
Prolonged cholestasis triggered by hepatitis A virus infection and variants of the hepatocanalicular phospholipid and bile salt transporters.
Ann Hepatol. 2012 Sep-Oct;11(5):710-4.

15.

Lammert F,  Märker-Hermann E,  Althoff A,  Espinola-Klein C, Fätkenhauer G,  Hampe J,  Knöll R,  Malek N, Mischak-Weissinger E,  Nickenig G, Schott M, Schulze-Lohoff E;
DGIM-Kommission Wissenschaft und Nachwuchsförderung.
Qualifizierungschancen für Nachwuchswissenschaftler in der Inneren Medizin
Dtsch Med Wochenschr. 2012 Aug;137(31-32):1586-8.

16.

Liu Y, Munker S, Müllenbach R, Weng HL.
IL-13 Signaling in Liver Fibrogenesis.
Front Immunol. 2012;3:116

17.

Mihalache F, Hoblinger A, Acalovschi M, Sauerbruch T, Lammert F, Zimmer V.
A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort.
Hepatobiliary Pancreat Dis Int. 2012 Aug;11(4):412-7.

18.

Müllenbach R, Weber SN, Lammert F.
Nuclear receptor variants in liver disease.
J Lipids. 2012;2012:934707

19.

Müllenbach R, Weber SN, Krawczyk M, Zimmer V, Sarrazin C, Lammert F, Günhage F.
A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population.
BMC Gastroenterol. 2012 Jun 8;12(1):63

20.

Nischalke HD, Coenen M, Berger C, Aldenhoff K, Müller T, Berg T, Krämer B, Körner C, Odenthal M, Schulze F, Grünhage F, Nattermann J, Sauerbruch T, Spengler U
The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C
Int J Cancer. 2012 Mar 15;130(6):1470-5

21.

Nischalke HD, Berger C, Luda C, Müller T, Berg T, Coenen M, Krämer B, Körner C, Trebicka J, Grünhage F, Lammert F, Nattermann J, Sauerbruch T, Spengler U.
The CXCL1 rs4074 A allele is associated with enhanced CXCL1 responses to TLR2 ligands and predisposes to cirrhosis in HCV genotype 1-infected Caucasian patients.
J Hepatol. 2012 Apr;56(4):758-64

22.

Plotz G, Casper M, Raedle J, Hinrichsen I, Heckel V, Brieger A, Trojan J, Zeuzem S.
MUTYH gene expression and alternative splicing in controls and polyposis patients.
Hum Mutat. 2012 Jul;33(7):1067-74

23.

Reichert MC, Lammert F.
Genetische Risikofaktoren tragen zur Entstehung der Divertikulose bei.
Z Gastroenterol. 2012 Oct;50(10):1114-5.

24.

Reichert MC, Bittenbring JT, Fries P, Zimmer V, Lammert F, Dauer M.
Recurrent pancreatitis caused by a huge intraluminal duodenal diverticulum.
J Gastrointestin Liver Dis. 2012 Jun;21(2):126.

25.

Slotta JE, Jüngling B, Kim YJ, Wagner M, Igna D, Schilling MK.
Hepatoid adenocarcinoma of the transverse colon.
Int J Colorectal Dis. 2012 Jul;27(7):989-91.

26.

Stokes CS, Lammert F.
Transporters in cholelithiasis.
Biol Chem. 2012 Jan 1;393(1-2):3-10

27.

Su X, Floyd DH, Hughes A, Xiang J, Schneider JG, Uluckan O, Heller E, Deng H, Zou W, Craft CS, Wu K, Hirbe AC, Grabowska D, Eagleton MC, Townsley S, Collins L, Piwnica-Worms D, Steinberg TH, Novack DV, Conley PB, Hurchla MA, Rogers M, Weilbaecher KN.
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
J Clin Invest. 2012 Oct 1;122(10):3579-92.

28.

Teufel A, Marquardt JU, Dooley S, Lammert F, Galle PR
Personalisierte Hepatologie − Gegenwärtige Konzepte, Entwicklungen und Erwartungen im Postgenomzeitalter
Z Gastroenterol. 2012 Jan;50(1):41-6.

29.

Teufel A, Becker D, Weber SN, Dooley S, Breitkopf-Heinlein K, Maass T, Hochrath K, Krupp M, Marquardt JU, Kolb M, Korn B, Niehrs C, Zimmermann T, Godoy P, Galle PR, Lammert F.
Identification of RARRES1 as a core regulator in liver fibrosis.
J Mol Med (Berl). 2012 Dec;90(12):1439-47.

30.

van der Meer AJ, Veldt BJ, Feld JJ, Wedemeyer H, Dufour JF, Lammert F, Duarte-Rojo A, Heathcote EJ, Manns MP, Kuske L, Zeuzem S, Hofmann WP, de Knegt RJ, Hansen BE, Janssen HL.
Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis.
JAMA. 2012 Dec 26;308(24):2584-93. doi: 10.1001/jama.2012.144878.

31.

von Heesen M, Schuld J, Sperling J, Grünhage F, Lammert F, Richter S, Schilling MK, Kollmar O.
Parenchyma-preserving hepatic resection for colorectal liver metastases.
Langenbecks Arch Surg. 2012 Mar;397(3):383-95

32.

von Kampen O, Buch S, Nothnagel M, Azocar L, Molina H, Brosch M, Erhart W, von Schönfels W, Egberts J, Seeger M, Arlt A, Balschun T, Franke A, Lerch MM, Mayerle J, Kratzer W, Boehm BO, Huse K, Schniewind B, Tiemann K, Jiang ZY, Han TQ, Mittal B, Srivastava A, Fenger M, Jørgensen T, Schirin-Sokhan R, Tönjes A, Wittenburg H, Stumvoll M, Kalthoff H, Lammert F, Tepel J, Puschel K, Becker T, Schreiber S, Platzer M, Völzke H, Krawczak M, Miquel JF, Schafmayer C, Hampe J.
Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus.
Hepatology. 2012 Aug 16. doi: 10.1002/hep.26009.

33.

Welker MW, Reichert D, Susser S, Sarrazin C, Martinez Y, Herrmann E, Zeuzem S, Piiper A, Kronenberger B.
Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity.
PLoS One. 2012;7(2):e30796.

34.

Wu Y, Li Q, Zhou X, Yu J, Mu Y, Munker S, Xu C, Shen Z, Müllenbach R, Liu Y, Li L, Gretz N, Zieker D, Li J, Matsuzaki K, Li Y, Dooley S, Weng H.
Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer.
PLoS One. 2012;7(4):e35684. Epub 2012 Apr 23.

35.

Zimmer V, Krawczyk M, Mahler M, Weber SN, Müllenbach R, Lammert F.
Severe hepatocellular dysfunction in obstetric cholestasis related to combined genetic variation in hepatobiliary transporters.
Clin Exp Obstet Gynecol. 2012;39(1):32-5

36.

Zimmer V, Rusticeanu M, Lammert F.
Brauereiarbeiter: Leberzirrhose – aber am Bier lag’s nicht
MMW Fortschr Med. 2012 Mar 8;154(4):5.

37.

Zimmer V, Lammert F
Capsule endoscopic celiac disease markers
QJM. 2012 Apr;105(4):377

38.

Zimmer V, Lammert F.
The "swinging" squamocolumnar junction in esophagocardiac achalasia.
Endoscopy. 2012 May;44 Suppl 2:E201

39.

Zimmer V, Höblinger A, Mihalache F, Assmann G, Acalovschi M, Lammert F.
Potential genotype-specific single nucleotide polymorphism interaction of common variation in p53 and its negative regulator mdm2 in cholangiocarcinoma susceptibility.
Oncol Lett. 2012 Jul;4(1):101-106.

40.

Zimmer V, Müller CS, Juengling B, Vogt T, Lammert F.
Esophageal intramural pseudodiverticulosis in mucous membrane pemphigoid: Potential diagnostic utility of C4d immunohistochemistry.
Dig Endosc. 2012 Nov;24(6):487.