Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Professur für Transplantations- und Infektionsimmunologie
Univ.-Prof. Dr. rer. nat. Martina Sester
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Aktuelle Publikationen

Hielscher, F., Schmidt, T., Klemis, V., Wilhelm, A., Marx, S., Abu-Omar, A., Ziegler, L., Guckelmus, C., Urschel, R., Sester, U., Widera, M., and Sester, M.

Cellular and humoral immunity towards SARS-CoV-2 wildtype and variants of concern after two doses of the NVX-CoV2373 vaccine in comparison to homologous BNT162b and mRNA1273 regimens.

J Clin Virol 2022, in press https://doi.org/10.1016/j.jcv.2022.105321  Impact Punkte: 14.481


Klemis, V., Schmidt, T., Schub, D., Mihm, J., Marx, S., Abu-Omar, A., Ziegler, L., Hielscher, F., Guckelmus, C., Urschel, R., Wagenpfeil, S., Schneitler, S., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M.
Comparative immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19-priming and BNT162b2 or mRNA-1273-boosting with homologous COVID-19 vaccine regimens.
Nat Commun 2022; Link zum Volltext.    Impact Punkte: 17.694.


Sester, M., and Becker, S.L.

Boosting immunity after CoronaVac.

Lancet 2022; 399:496-497.    Impact Punkte: 202.731.


Abu-Omar, A., and Sester, M.

Ways to boost cellular immunity in solid organ transplant recipients – the case of letermovir.

Tranplant Inf Dis 2022; in press. Impact Punkte: 2,228.


Karakizlis, H., Nahrgang, C., Strecker, K., Chen, J., Aly, M., Slanina, H., Schuttler, C.G., Esso, I., Wolter, M., Todorova, D., Jessen, S., Adamik, A., Ronco, C., Seeger, W., Weimer, R., Sester, M., Birk, H.W., and Husain-Syed, F.

Immunogenicity and reactogenicity of homologous mRNA-based and vector-based SARS-CoV-2 vaccine regimens in patients receiving maintenance dialysis.

Clin Immunol 2022; 236:108961.    Impact Punkte: 10.190.


Karakizlis, H., Agarwal, V., Aly, M., Strecker, K., Csala, B., Esso, I., Chen, J., Nahrgang, C., Wolter, M., Slanina, H., Schuttler, C.G., Jessen, S., Ronco, C., Seeger, W., Weimer, R., Sester, M., Birk, H.W., and Husain-Syed, F.
Humoral and cellular immune responses to the mRNA-1273 SARS-CoV-2 vaccine booster in patients on maintenance dialysis.
J Nephrol 2022.    Impact Punkte: 4.439.


Karakizlis, H., Nahrgang, C., Strecker, K., Chen, J., Aly, M., Slanina, H., Schuttler, C.G., Esso, I., Wolter, M., Todorova, D., Jessen, S., Adamik, A., Ronco, C., Seeger, W., Weimer, R., Sester, M., Birk, H.W., and Husain-Syed, F.

Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis.

Data Brief 2022; 42:108271. 


Goi, J.R., Merzou, F., Lochner, P., Sester, M., Schmidt, T., Schub, D., Kettner, M., Fassbender, K., and Fousse, M.

Cerebral Sinus Vein Thrombosis in two patients with AstraZeneca SARS-CoV-2 vaccination.

J Neurology 2021; in press. Impact Punkte: 6.682.


Schmidt, T.Klemis, V.Schub, D., Schneitler, S., Reichert, M.C., Wilkens, H., Sester, U., Sester, M., and Mihm, J.

Cellular immunity predominates over humoral immunity after homologous and heterologous mRNA and vector-based COVID-19 vaccine regimens in solid organ transplant recipients.

Am J Transplant 2021. Zugang zum Volltext Impact Punkte: 9.369


Schmidt, T.Klemis, V., Schub, D., Mihm, J., Hielscher, F.Marx, S.Abu-Omar, A.Ziegler, L.Guckelmus, C.Urschel, R., Schneitler, S., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M.

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination.

Nat Med 2021; 27:1530-1535.   Zugang zum Volltext Impact Punkte: 87.241.


Simon, A., Reinhardt, T., Meyer, S., Baltaci, Y., Rissland, J., Eichler, H., Klemis, V.Sester, M., and Graf, N.

COVID-19 in a pediatric cancer patient with T-lymphoblastic lymphoma: response to convalescence plasma and subsequent induction of SARS-CoV-2 specific humoral and cellular immunity despite strong B-cell lymphopenia.

Journal of clinical images and medical case reports 2021; 2.


Gärtner, B.C., and Sester, M.

Diversity of antibody responses after influenza infection or vaccination-Needed or nice to have?

Am J Transplant 2021; 21:2631-2632. Zugang zum Volltext Impact Punkte: 9.369.


Blumberg, E.A., Manuel, O., Sester, M., and Ison, M.G.

The future of SARS-CoV-2 vaccines in transplant recipients: To be determined.

Am J Transplant 2021; 21:2629-2630 Zugang zum Volltext Impact Punkte: 9.369.


Danziger-Isakov, L., Blumberg, E., Manuel, O., and Sester, M.

Impact of COVID-19 in solid organ transplant recipients.

Am J Transplant 2021; 21:925-937. Zugang zum Volltext Impact Punkte: 9.369.


Wiening, V., Schmidt, T., Dahmen, M., Siam, S., Reuter, S., Pavenstädt, H.-J., Sester, M., and Suwelack, B.

Management of a multidrug-resistant CMV-strain in a renal transplant recipient by high-dose CMV-specific immunoglobulins, modulation in immunosuppression and induction of CMV-specific cellular immunity – a case report.

Frontiers in Immunology 2021;11:623178. Zugang zum Volltext Impact Punkte: 8.786.


Hauser, I.A.*, Marx, S.*, Sommerer, C., Suwelack, B., Dragun, D., Witzke, O., Lehner, F., Schiedel, C., Junge, M., Thaiss, F., Neudörfl, C., Falk, C.S., Nashan, B., and Sester, M.

Effect of everolimus-based immunosuppression regimens on cytomegalovirus-specific T-cell functionality after renal transplantation: 12-month results from the ATHENA study.

Eur J Immunol 2020; 51:943-955. Zugang zum Volltext Impact Punkte: 6.688. *geteilte Erstautorinnenschaft.


Gupta, R.K., Calderwood, C.J., Yavlinsky, A., Krutikov, M., Quartagno, M., Aichelburg, M.C., Altet, N., Diel, R., Dobler, C.C., Dominguez, J., Doyle, J.S., Erkens, C., Geis, S., Haldar, P., Hauri, A.M., Hermansen, T., Johnston, J.C., Lange, C., Lange, B., van Leth, F., Muñoz, L., Roder, C., Romanowski, K., Roth, D., Sester, M., Sloot, R., Sotgiu, G., Woltmann, G., Yoshiyama, T., Zellweger, J.P., Zenner, D., Aldridge, R.W., Copas, A., Rangaka, M.X., Lipman, M., Noursadeghi, M., and Abubakar, I.

Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.

Nat Med 2020; in press. Abstract Impact Punkte: 53.440.


Schub, D.Klemis, V., Schneitler, S., Mihm, J., Lepper, P.M., Wilkens, H., Bals, R., Eichler, H., Gärtner, B.C., Becker, S.L., Sester, U., Sester, M., and Schmidt, T.

High levels of SARS-CoV-2 specific T-cells with restricted functionality in severe course of COVID-19.
JCI Insight 2020. in press. Impact Punkte: 8.315. Link zum Volltext


Kos, I., Balensiefer, B., Roth, S., Ahlgrimm, M., Sester, M.Schmidt, T., Thurner, L., Bewarder, M., Bals, R., Lammert, F., Stilgenbauer, S., and Kaddu-Mulindwa, D.

Prolonged course of COVID-19-associated pneumonia in a B-cell depleted patient after rituximab.

Frontiers in Oncology 2020; in press. Impact Punkte: 6.244. Link zum Volltext


Diener, C., Hart, M., Kehl, T., Rheinheimer, S., Ludwig, N., Krammes, L., Pawusch, S., Lenhof, K., Tänzer, T., Schub, D.Sester, M., Walch-Rückheim, B., Keller, A., Lenhof, H.P., and Meese, E.

Quantitative and time-resolved miRNA pattern of early human T cell activation.

Nucleic Acids Res 2020; 48:10164-10183. Impact Punkte: 16.971. Abstract


Marx, S., Adam, C., Weyrich, M., Mihm, J., Sester, U., and Sester, M.

A polyclonal immune function assay allows dose-dependent characterization of immunosuppressive drug effects but has limited clinical utility for predicting infection on an individual basis.

Frontiers in Immunology 2020; Link zum Volltext.    Impact Punkte: 7.561.


Abdulnasser Harfoush, S., Hannig, M., Le, D.D., Heck, S., Leitner, M., Omlor, A.J., Tavernaro, I., Kraegeloh, A., Kautenburger, R., Kickelbick, G., Beilhack, A., Bischoff, M., Nguyen, J., Sester, M., Bals, R., and Dinh, Q.T.

High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice.
Respir Res 2020; 21:168. Impact Punkte: 4.065. Abstract


Stenger, T., Ledo, A., Ziller, C., Schub, D., Schmidt, T., Enders, M., Gärtner, B.C., Sester, M., and Meyer, T.
Timing of vaccination after training: Immune response and side effects in athletes.
Med Sci Sports Exerc 2020; In press.    Impact Punkte: 5.411. Abstract


Ahlenstiel-Grunow, T., Sester, M., Sester, U., Hirsch, H.H., and Pape, L.

BK Polyomavirus-specific T Cells as a Diagnostic and Prognostic Marker for BK Polyomavirus Infections After Pediatric Kidney Transplantation.

Transplantation 2020; in press    Impact Punkte: 4.939. Abstract


Ledo, A., Schub, D., Ziller, C., Enders, M., Stenger, T., Gärtner, B.C., Schmidt, T., Meyer, T., and Sester, M.

Elite athletes on regular training show more pronounced induction of influenza-specific T-cells and antibodies after tetravalent influenza vaccination than controls.
Brain Behav Immun 2020; 83:135-145.    Impact Punkte: 7.217. Abstract


Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Klug, M., Triem, S., Schunk, S.J., Schmit, D., Kramann, R., Körbel, C., Ampofo, E., Laschke, M., Selejan, S.-R., Schuster, S., Silbernagel, G., Sester, M., Sester, U., Assmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M.D., Rohrer, L., März, W., Böhm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B.A., Fliser, D., Laufs, U., and Speer, T.

Apolipoprotein C3 induces systemic inflammation and organ damage by alternative inflammasome activation.
Nat Immunol 2020; 21:30-41.    Impact Punkte: 25.606. Abstract


Publikationen M. Sester

42 (scopus)
50 (google scholar)
>100 Medline-gelistete Arbeiten