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Ausgewählte Originalpublikationen AG Smola

• Fröhlich F, Gronwald B, Bay J, Simon A, Poryo M, Geisel J, Tegethoff SA, Last K, Rissland J, Smola S, Becker SL, Zemlin M, Meyer S, Papan C.
  Expression of TRAIL, IP-10, and CRP in children with suspected COVID-19 and real-life impact of a computational signature on clinical decision-making: a prospective cohort study.
  Infection. 2023:1-8. doi: 10.1007/s15010-023-01993-1.  
• Thurner L, Kessel C, Fadle N, Regitz E, Seidel F, Kindermann I, Lohse S, Kos I, Tschöpe C, Kheirodin P, Kiblboeck D, Hoffmann M-C, Bette B, Carbon G, Cetin O, Preuss K-D, Christofyllakis K, Bittenbring JT, Pickardt T, Fischer Y, Thiele H, Baldus S, Stangl K, Steiner S, Gietzen F, Kerber S, Deneke T, Jellinghaus S, Linke A, Ibrahim K, Grabmaier U, Massberg S, Thilo C, Greulich S, Gawaz M, Mayatepek E, Meyer-Dobkowitz L, Kindermann M, Birk E, Birk M, Lainscak M, Foell D, Lepper PM, Bals R, Krawczyk M, Mevorach D, Hasin T, Keren A, Kabesch M, Abdul-Khaliq H, Smola S, Bewarder M, Thurner B, Böhm M, Pfeifer J, Klingel K.
  IL-1-Ra-Antibodies in Myocarditis following SARS-CoV-2 Vaccination.
  N Engl J Med. 2022 Oct 20;387(16):1524-1527. doi: 10.1056/NEJMc2205667.
• Pfeifer J, Thurner B, Kessel C, Fadle N, Kheiroddin P, Regitz E, Hoffmann MC, Kos IA, Preuss KD, Fischer Y, Roemer K, Lohse S, Heyne K, Detemple MC, Fedlmeier M, Juenger H, Sauer H, Meyer S, Rohrer T, Wittkowski H, Becker SL, Masjosthusmann K, Bals R, Gerling S, Smola S, Bewarder M, Birk E, Keren A, Böhm M, Jakob A, Abdul-Khaliq H, Anton J, Kabesch M, Pino-Ramirez RM, Foell D, Thurner L.
  Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study.
  Lancet Rheumatol. 2022 Mar 29. doi: 10.1016/S2665-9913(22)00064-9.
• Bock T, Bewarder M, Cetin O, Fadle N, Regitz E, Schwarz E, Held J, Roth S, Lohse S, Pfuhl T, Wagener R, Smola S, Becker S, Bohle RM, Trümper L, Siebert R, Hansmann M-L, Pfreundschuh M, Drexler H, Hoth M, Kubuschok B, Roemer K, Preuss KD, Hartmann S, Thurner L.
  B-cell receptors of EBV-negative Burkitt lymphoma bind modified isoforms of autoantigens.
  eJHaem. 2022 Jun 16;3(3):739-747. doi: 10.1002/jha2.475. eCollection 2022 Aug.
• Lohse S, Sternjakob-Marthaler A, Lagemann P, Schope J, Rissland J, Seiwert N, Pfuhl T, Mullendorff A, Kiefer LS, Vogelgesang M, Vella L, Denk K, Vicari J, Zwick A, Lang I, Weber G, Geisel J, Rech J, Schnabel B, Hauptmann G, Holleczek B, Scheiblauer H, Wagenpfeil S, Smola S.

  German federal-state-wide seroprevalence study of 1(st) SARS-CoV-2 pandemic wave shows importance of long-term antibody test performance.
  Commun Med. 2022;2:52.

• Sternjakob-Marthaler A, Berkó-Göttel B, Rissland J, Schöpe J, Taurian E, Müller H, Weber G, Lohse S, Lamberty T, Holleczek B, Stoffel H, Hauptmann G, Giesen M, Firk C, Schanzenbach A, Brandt F, Hohmann H, Werthner D, Selzer D, Lehr T, Wagenpfeil S, Smola S.
  Human papillomavirus vaccination of girls in the German model region Saarland: Insurance data-based analysis and identification of starting points for improving vaccination rates.
  Plos One. 2022 Sep 2;17(9):e0273332. doi: 10.1371/journal.pone.0273332. eCollection 2022.

• Eisenberg L, The XplOit consortium*, Brossette C, Rauch J, Grandjean A, Ottinger H, Rissland J, Schwarz U, Graf N, Beelen DW, Kiefer S, Pfeifer N, Turki AT.
  Time-dependent prediction of mortality and cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation using machine learning.
  *Smola S is part or the XplOit consortium and one of the applicants of the project.
  American Journal of Hematology. 2022 Oct;97(10):1309-1323.  doi: 10.1002/ajh.26671.

• Bley IA, Zwick A, Hans MC, Thieser K, Wagner V, Ludwig N, Khalmurzaev O, Matveev VB, Loertzer P, Pryalukhin A, Hartmann A, Geppert CI, Loertzer H, Wunderlich H, Naumann CM, Kalthoff H, Junker K, Smola S, Lohse S.
  DKK1 inhibits canonical Wnt signaling in human papillomavirus-positive penile cancer cells.
  Transl Oncol. 2022 Jan;15(1):101267. doi: 10.1016/j.tranon.2021.101267.

• Kos IA, Kiefer M, Brill K, Cetin O, Bittenbring JT, Ahlgrimm M, Smola S, Lohse S, Christofyllakis K, Kaddu-Mulindwa D, Neumann F, Bewarder M, Thurner L.
  Adaptive Humoral Immune Response and Cellular Immune Status in Cancer Patients and Patients under Immunosuppression Vaccinated against SARS-CoV-2.
  Expert Review of Vaccines. 2022 Nov;21(11):1683-1689. doi: 10.1080/14760584.2022.2116009.

• Toth G, Berko-Gottel B, Seitz B, Langenbucher A, Stachon T, Pluzsik MT, Nagy ZZ, Smola S*, Szentmary N*. *shared senior authorships
  Herpes simplex virus PCR in 2230 explanted corneal buttons.
  Acta Ophthalmol. 2022 Feb;100(1):e77-e82. doi: 10.1111/aos.14872.

• Tegethoff SA, Danziger G, Kuhn D, Kimmer C, Adams T, Heintz L, Metz C, Reifenrath K, Angresius R, Mang S, Rixecker T, Becker A, Geisel J, Jentgen C, Seiler F, Reichert MC, Frohlich F, Meyer S, Rissland J, Ewen S, Wagenpfeil G, Last K, Smola S, Bals R, Lammert F, Becker SL, Krawczyk M, Lepper PM, Papan C.
  TNF-related apoptosis-inducing ligand, interferon gamma-induced protein 10, and C-reactive protein in predicting the progression of SARS-CoV-2 infection: a prospective cohort study.
  Int J Infect Dis. 2022 Sep;122:178-187. doi: 10.1016/j.ijid.2022.05.051.

• Kaddu-Mulindwa D, Keuser L, Lesan V, Rissland J, Smola S, Werdecker V, Stilgenbauer S, Christofyllakis K, Thurner L, Bewarder M, Lohr B, Lutz J, Lohse S, Rieke A.
  IgG seroprevalence of COVID-19 among people living with HIV or at high risk of HIV in south-west Germany: A seroprevalence study.
  HIV Med. 2022 May;23(5):564-569. doi: 10.1111/hiv.13207. Epub 2021 Nov 22.

• Becker M, Strengert M, Junker D, Kaiser PD, Kerrinnes T, Tränkle B, Dinter H, Häring J, Ghozzi, S, Zeck A, Weise F, Peter A, Hörber S, Fink S, Ruoff F, Dulcovic A, Bakchoul T, Baillot A, Lohse S, Cornberg M, Illig T, Gottlieb J, Smola S, Karch A, Berger K, Rammensee KG, Schenke-Layland K, Nelde A, Märlkin A, Heitmann JS, Walz JS, Templin M, Joos TO, Rothbauer U, Krause G, Schneiderhan-Marra N.
  Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity.
  Nature Communications. 2021 Feb 19;12(1):1152. doi: 10.1038/s41467-021-20973-3.

• Bernhard MC, Zwick A, Mohr T, Gasparoni G, Khalmurzaev O, Matveev VB, Loertzer P, Pryalukhin A, Hartmann A, Geppert CI, Loertzer H, Wunderlich H, Naumann CM, Kalthoff H, Junker K, Smola S, Lohse S.
  The HPV and p63 Status in Penile Cancer Are Linked with the Infiltration and Therapeutic Availability of Neutrophils.
  Mol Cancer Ther. 2021 Feb;20(2):423-437. doi: 10.1158/1535-7163.MCT-20-0173. Epub 2020 Dec 3.

• Theobald L, Stroeder R, Melchior P, Iordache II, Tänzer T, Port M, Glombitza B, Marx S, Schub D, Herr C, Hart M, Ludwig N, Meese E, Kim YJ, Bohle RM, Smola S, Rübe C, Solomayer EF, Walch-Rückheim B.
  Chemoradiotherapy-induced increase in Th17 cell frequency in cervical cancer patients is associated with therapy resistance and early relapse.
  Mol Oncol. 2021 Dec;15(12):3559-3577. doi: 10.1002/1878-0261.13095.

• Kühn JP, Schmid W, Körner S, Bochen F, Wemmert S, Rimbach H, Smola S, Radosa JC, Wagner M, Morris LGT, Bozzato V, Bozzato A, Schick B, Linxweiler M.
  HPV Status as Prognostic Biomarker in Head and Neck Cancer-Which Method Fits the Best for Outcome Prediction?
  Cancers (Basel). 2021 Sep 21;13(18):4730. doi: 10.3390/cancers13184730.

• Herr C, Mang S, Mozafari B, Guenther K, Speer T, Seibert M, Srikakulam SK, Beisswenger C, Ritzmann F, Keller A, Mueller R, Smola S, Eisinger D, Zemlin M, Danziger G, Volk T, Hoersch S, Krawczyk M, Lammert F, Adams T, Wagenpfeil G, Kindermann M, Marcu C, Ataya ZWD, Mittag M, Schwarzkopf K, Custodis F, Grandt D, Schaefer H, Eltges K, Lepper PM, Bals R; CORSAAR Study Group.
  Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19.
  J Inflamm Res. 2021 Sep 15;14:4651-4667. doi: 10.2147/JIR.S320685. eCollection 2021.

• Joachim A, Dewald F, Suárez I, Zemlin M, Lang I, Stutz R, Marthaler A, Bosse HM, Lübke N, Münch J, Bernard MA, Jeltsch K, Tönshoff B, Weidner N, Kräusslich HG, Birzele L, Hübner J, Schmied P, Meyer-Bühn M, Horemheb-Rubio G, Cornely OA, Haverkamp H, Wiesmüller G, Fätkenheuer G, Hero B, Kaiser R, Dötsch J, Rybniker J; B-FAST study group*.* Smola S is part of the B-FAST study group.
  Pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools - a cluster randomised trial.
  EClinicalMedicine. 2021 Sep;39:101082. doi: 10.1016/j.eclinm.2021.101082. Epub 2021 Aug 25.

• Ritzmann F, Chitirala P, Krüger N, Hoffmann M, Zuo W, Lammert F, Smola S, Tov N, Alagem N, Lepper PM, Pöhlmann S, Beisswenger C, Herr C, Bals R; AAT-in-COVID-19 Study Group.
  Therapeutic Application of Alpha-1 Antitrypsin in COVID-19.
  Am J Respir Crit Care Med. 2021 Jul 15;204(2):224-227. doi: 10.1164/rccm.202104-0833LE.

• Tierling S, Kattler K, Vogelgesang M, Pfuhl T, Lohse S, Lo Porto C, Schmitt B, Seiwert N, Salhab A, Smola S, Walter J.
  Rapid Base-Specific Calling of SARS-CoV-2 Variants of Concern Using Combined RT-PCR Melting Curve Screening and SIRPH Technology.
  Open Forum Infect Dis. 2021 Jul 14;8(8):ofab364. doi: 10.1093/ofid/ofab364. eCollection 2021 Aug.

• Kos I, Balensiefer B, Lesan V, Kaddu-Mulindwa D, Thurner L, Christofyllakis K, Bittenbring JT, Ahlgrimm M, Seiffert M, Wagenpfeil S, Bewarder Y, Neumann F, Rixecker T, Smola S, Link A, Krawczyk M, Lammert F, Lepper PM, Bals R, Stilgenbauer S, Bewarder M.
  Increased B-cell activity with consumption of activated monocytes in severe COVID-19 patients.
  Eur J Immunol. 2021 Jun;51(6):1449-1460. doi: 10.1002/eji.202049163. Epub 2021 Apr 19.

• Kaddu-Mulindwa D, Thurner L, Bewarder M, Murawski N, Ahlgrimm M, Pfuhl T, Gärtner B, Smola S, Stilgenbauer S.
  Protection strategy against outbreak of COVID-19 at a tertiary hematology-oncology: strengths and pitfalls.
  Infect Agent Cancer. 2021 Feb 24;16(1):17. doi: 10.1186/s13027-021-00356-5.

• Tóth G, Berkó-Göttel B, Seitz B, Langenbucher A, Stachon T, Pluzsik MT, Nagy ZZ, Smola S, Szentmáry N.
  Herpes simplex virus PCR in 2230 explanted corneal buttons.
  Acta Ophthalmol. 2021 Jun 14. doi: 10.1111/aos.14872.

• Tóth G, Xanthopoulou K, Stachon T, Németh J, Hécz R, Berkó-Göttel B, Pfuhl T, Smola S, Seitz B, Szentmáry N.
  Impact of COVID-19 Pandemic on Emergency Inpatient Volume at a Tertiary Eye Care Center in Germany with Corneal Main Specialization.
  Klin Monbl Augenheilkd. 2021 Jun;238(6):715-720. doi: 10.1055/a-1327-3393. Epub 2021 Mar 17.

• Lohse S, Pfuhl T, Berkó-Göttel B, Rissland J, Geißler T, Gärtner B, Becker SL, Schneitler S, Smola S.
  Pooling of samples for testing for SARS-CoV-2 in asymptomatic people.
  Lancet Infect Dis. 2020 Nov;20(11):1231-1232. doi: 10.1016/S1473-3099(20)30362-5. Epub 2020 Apr 28.

• Lohse S, Pfuhl T, Berkó-Göttel B, Gärtner B, Becker SL, Schneitler S, Smola S.
  Challenges and issues of SARS-CoV-2 pool testing - Authors' reply.
  Lancet Infect Dis. 2020 Nov;20(11):1234-1235. doi: 10.1016/S1473-3099(20)30455-2. Epub 2020 Jul 14.

• Mang S, Kaddu-Mulindwa D, Metz C, Becker A, Seiler F, Smola S, Maßmann A, Becker SL, Papan C, Bals R, Lepper PM, Danziger G.
  Pneumocystis Jirovecii Pneumonia and SARS-CoV-2 Co-Infection in newly diagnosed HIV-1 infection.
  Clin Infect Dis. 2020 Jul 1:ciaa906. doi: 10.1093/cid/ciaa906.

• Schneitler S, Jung P, Bub F, Alhussein F, Benthien S, Berger FK, Berkó-Göttel B, Eisenbeis J, Hahn D, Halfmann A, Last K, Linxweiler M, Lohse S, Papan C, Pfuhl T, Rissland J, Roth S, Schlotthauer U, Utzinger J, Smola S, Gärtner BC, Becker SL.
  Simple Questionnaires to Improve Pooling Strategies for SARS-CoV-2 Laboratory Testing.
  Ann Glob Health. 2020 Nov 18;86(1):148. doi: 10.5334/aogh.3126.

• Bewarder M, Held G, Thurner L, Stilgenbauer S, Smola S, Preuss KD, Carbon G, Bette B, Christofyllakis K, Bittenbring JT, Felbel A, Hasse A, Murawski N, Kaddu-Mulindwa D, Neumann F.
  Characterization of an HLA-restricted and human cytomegalovirus-specific antibody repertoire with therapeutic potential.
  Cancer Immunol Immunother. 2020 Aug;69(8):1535-1548. doi: 10.1007/s00262-020-02564-1. Epub 2020 Apr 16.

• Schwarz V, Mahfoud F, Lauder L, Reith W, Behnke S, Smola S, Rissland J, Pfuhl T, Scheller B, Böhm M, Ewen S.
  Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19.
  Clin Res Cardiol. 2020 Dec;109(12):1500-1506. doi: 10.1007/s00392-020-01688-9. Epub 2020 Aug 4.

• Zwick A, Bernhard M, Knoerck A, Linxweiler M, Schick B, Heinzelmann J, Smola S, Lohse S.
  Monitoring kinetics reveals critical parameters of IgA-dependent granulocyte-mediated anti-tumor cell cytotoxicity.
  J Immunol Methods. 2019 Oct;473:112644. doi: 10.1016/j.jim.2019.112644. Epub 2019 Aug 9.

• Walch-Rückheim B, Ströder R, Theobald L, Pahne-Zeppenfeld J, Hegde S, Kim YJ, Bohle RM, Juhasz-Böss I, Solomayer EF, Smola S.
  Cervical Cancer-Instructed Stromal Fibroblasts Enhance IL23 Expression in Dendritic Cells to Support Expansion of Th17 Cells.
  Cancer Res. 2019 79:1573-1586.

• Müller CSL, Kreie L, Bochen F, Pfuhl T, Smola S, Gräber S, Vogt T, Schick B, Linxweiler M.
  Expression of 3q oncogene SEC62 in atypical fibroxanthoma-immunohistochemical analysis of 41 cases and correlation with clinical, viral and histopathologic features.
  Oncol Lett.2019 Feb;17(2):1768-1776. doi: 10.3892/ol.2018.9767. Epub 2018 Nov 27.

• Hölters S, Khalmurzaev O, Pryalukhin A, Loertzer P, Janssen M, Heinzelbecker J, Ueberdiek S, Pfuhl T, Smola S, Agaimy A, Geppert C, Loertzer H, Krah X, Wunderlich H, Wagenpfeil S, Bohle RM, Stöckle M, Matveev V, Hartmann A, Junker K.
  Challenging the prognostic impact of the new WHO and TNM classifications with special emphasis on HPV status in penile carcinoma.
  Virchows Arch. 2019 Aug;475(2):211-221. doi: 10.1007/s00428-019-02566-0. Epub 2019 Apr 10.

• Peretti A, Geoghegan EM, Pastrana DV, Smola S, Feld P, Sauter M, Lohse S, Ramesh M, Lim ES, Wang D, Borgogna C, FitzGerald PC, Bliskovsky V, Starrett GJ, Law EK, Harris RS, Killian JK, Zhu J, Pineda M, Meltzer PS, Boldorini R, Gariglio M, Buck CB.
  Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution.
  Cell Host Microbe. 2018;23:628-35 e7.

• Podgorska M, Oldak M, Marthaler A, Fingerle A, Walch-Ruckheim B, Lohse S, Muller CSL, Vogt T, Ustav M, Wnorowski A, Malejczyk M, Majewski S, Smola S.
  Chronic Inflammatory Microenvironment in Epidermodysplasia Verruciformis Skin Lesions: Role of the Synergism Between HPV8 E2 and C/EBPbeta to Induce Pro-Inflammatory S100A8/A9 Proteins.
  Front Microbiol. 2018;9:392.

• Wemmert S, Linxweiler M, Lerner C, Bochen F, Kulas P, Linxweiler J, Smola S, Urbschat S, Wagenpfeil S, Schick B.
  Combinational chromosomal aneuploidies and HPV status for prediction of head and neck squamous cell carcinoma prognosis in biopsies and cytological preparations.
  J Cancer Res Clin Oncol. 2018;144:1129-41.

• Weiler G, Schwarz U, Rauch J, Rohm K, Lehr T, Theobald S, Kiefer S, Gotz K, Och K, Pfeifer N, Handl L, Smola S, Ihle M, Turki AT, Beelen DW, Rissland J, Bittenbring J, Graf N. XplOit: An Ontology-Based Data Integration Platform Supporting the Development of Predictive Models for Personalized Medicine.
  Stud Health Technol Inform. 2018;247:21-5.

• Stroeder R, Walch-Rückheim B, Fischbach J, Juhasz-Böss I, Rübe C, Solomayer EF, Smola S.
  Oncostatin M treatment increases the responsiveness toward cisplatin-based chemoradiotherapy in cervical cancer cells in a STAT3-dependent manner.
  Oncol Lett. 2018 Sep;16(3):3351-3358. doi: 10.3892/ol.2018.8987. Epub 2018 Jun 18.

• Marthaler AM, Podgorska M, Feld P, Fingerle A, Knerr-Rupp K, Grässer F, Smola H, Roemer K, Ebert E, Kim YJ, Bohle RM, Müller CSL, Reichrath J, Vogt T, Malejczyk M, Majewski S, Smola S.
  Identification of C/EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes.
  PLoS Pathogens. 2017 2017 Jun 22;13(6):e1006406.

• Bochen F, Adisurya H, Wemmert S, Lerner C, Greiner M, Zimmermann R, Hasenfus A, Wagner M, Smola S, Pfuhl T, Bozzato A, Al Kadah B, Schick B, Linxweiler M.
  Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas.
  Oncotarget. 2017;8:4922-4934.

• Titze MI, Frank J, Ehrhardt M, Smola S, Graf N, Lehr T.
  A generic viral dynamic model to systematically characterize the interaction between oncolytic virus kinetics and tumor growth.
  Eur J Pharm Sci. 2017;97:38-46.

• Walch-Ruckheim B, Pahne-Zeppenfeld J, Fischbach J, Wickenhauser C, Horn LC, Tharun L, Büttner R, Mallmann P, Stern P, Kim YJ, Bohle RM, Rübe C, Ströder R, Juhasz-Boss I, Solomayer EF, Smola S.
  STAT3/IRF1 pathway activation sensitizes cervical cancer cells for chemotherapeutic drugs.
  Cancer Res. 2016;76:3872-83.

• Mihm J, Leyking S, Dirks J, Smola S, Fliser D, Sester U, Sester M, Wilkens H, Rissland J.
  Immune-based guidance of foscarnet treatment duration in a transplant recipient with ganciclovir-resistant cytomegalovirus infection.
  J Clin Virol. 2016;82:5-8.

• Walch-Ruckheim B, Mavrova R, Henning M, Vicinus B, Kim YJ, Bohle RM, Juhasz-Boss I, Solomayer EF, Smola S.
  Stromal Fibroblasts Induce CCL20 through IL6/C/EBPbeta to Support the Recruitment of Th17 Cells during Cervical Cancer Progression.
  Cancer Res .2015;75:5248-59.

• Rolfs F, Huber M, Kuehne A, Kramer S, Haertel E, Muzumdar S, Wagner J, Tanner Y, Bohm F, Smola S, Zamboni N, Levesque MP, Dummer R, Beer HD, Hohl D, Werner S, Schafer M.
  Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations.
  Cancer Res. 2015;75:4817-29.

• Schmidt SV, Seibert S, Walch-Ruckheim B, Vicinus B, Kamionka EM, Pahne-Zeppenfeld J, Solomayer EF, Kim YJ, Bohle RM, Smola S.
  RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1alpha release, and efficient paracrine dendritic cell activation.
  Oncotarget 2015;6:8635-47.

• Strittmatter GE, Sand J, Sauter M, Seyffert M, Steigerwald R, Fraefel C, Smola S, French LE, Beer HD.
  IFN-gamma primes keratinocytes for HSV-1-induced inflammasome activation.
  J Invest Dermatol. 2015..

• Schub D, Janssen E, Leyking S, Sester U, Assmann G, Hennes P, Smola S, Vogt T, Rohrer T, Sester M, Schmidt T.
  Altered phenotype and functionality of varicella zoster virus-specific cellular immunity in individuals with active infection.
  J Infect Dis. 2015;211:600-12.

• Held G, Luescher IF, Neumann F, Papaioannou C, Schirrmann T, Sester M, Smola S, Pfreundschuh M.
  MHC/Peptide-Specific Interaction of the Humoral Immune System: A New Category of Antibodies.
  J Immunol. 2015;195:4210-7.

• Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgorska M, Smola S, Hoth M, Zufall F.
  Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens.
  J Biol Chem. 2015;290:7369-87.

• Linxweiler M, Bochen F, Wemmert S, Lerner C, Hasenfus A, Bohle RM, Al-Kadah B, Takacs ZF, Smola S, Schick B.
  Combination of p16(INK4a) /Ki67 immunocytology and HPV polymerase chain reaction for the noninvasive analysis of HPV involvement in head and neck cancer.
  Cancer Cytopathol. 2015;123:219-29.

• Pahne-Zeppenfeld J, Schroer N, Walch-Ruckheim B, Oldak M, Gorter A, Hegde S, Smola S.
  Cervical cancer cell-derived interleukin-6 impairs CCR7-dependent migration of MMP-9-expressing dendritic cells.
  Int J Cancer. 2014;134:2061-73.

• Tappe D, Rissland J, Gabriel M, Emmerich P, Gunther S, Held G, Smola S, Schmidt-Chanasit J.
  First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013.
  Euro Surveill 2014;19.

• Sperling T, Ołdak M, Walch-Rückheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S.
  Human Papillomavirus Type 8 Interferes with a Novel C/EBPbeta-Mediated Mechanism of Keratinocyte CCL20 Chemokine Expression and Langerhans Cell Migration.
  PLoS Pathogens. 2012;8:e1002833.
  Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, Bischof G, Vollmer J, Smola S, Schmidt B.
  Chronic Immune Activation in HIV-1 Infection Contributes to Reduced Interferon Alpha Production via Enhanced CD40:CD40 Ligand Interaction.
  PLoS One. 2012;7:e33925.

• Schroer N, Pahne J, Walch B, Wickenhauser C, Smola S.
  Molecular Pathobiology of Human Cervical High-Grade Lesions: Paracrine STAT3 Activation in Tumor-Instructed Myeloid Cells Drives Local MMP-9 Expression.
  Cancer Res. 2011;71:87-97.
  Oldak M, Tolzmann L, Wnorowski A, Podgorska MJ, Silling S, Lin R, Hiscott J, Muller CS, Vogt T, Smola H, Smola S.
  Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7.
  J Virol. 2011;85:178-88.

Ausgewählte Übersichtsartikel

• Gross GE, Werner RN, Avila Valle GL, Bickel M, Brockmeyer NH, Doubek K, Gallwas J, Gieseking F, Haase H, Hillemanns P, Ikenberg H, Jongen J, Kaufmann AM, Klußmann JP, von Knebel Doeberitz M, Knuf M, Köllges R, Laws HJ, Mikolajczyk R, Neis KJ, Petry KU, Pfister H, Schlaeger M, Schneede P, Schneider A, Smola S, Tiews S, Nast A, Gaskins M, Wieland U.
  German evidence and consensus-based (S3) guideline: Vaccination recommendations for the prevention of HPV-associated lesions.
  J Dtsch Dermatol Ges. 2021 Mar;19(3):479-494. doi: 10.1111/ddg.14438. Epub 2021 Feb 26.
• Smola S
  Human Papillomaviruses and Skin Cancer.
  Adv Exp Med Biol. 2020;1268:195-209. doi: 10.1007/978-3-030-46227-7_10.
• Smola S
  Immune deviation and cervical carcinogenesis.
  Papillomavirus Res. 2019 Jun;7:164-167. doi: 10.1016/j.pvr.2019.03.006. Epub 2019 Apr 10.
• Venuti A, Lohse S, Tommasino M, Smola S.
  Cross-talk of cutaneous beta human papillomaviruses and the immune system: determinants of disease penetrance.
  Philos Trans R Soc Lond B Biol Sci. 2019 May 27;374(1773):20180287.
• Pfister HJ, Gariglio M, Smola S.
  Editorial: Human Papillomaviruses and Polyomaviruses in Skin Cancer.
  Front Microbiol. 2018 Nov 15;9:2778. doi: 10.3389/fmicb.2018.02778. eCollection 2018.
• Smola S.
  Immunopathogenesis of HPV-Associated Cancers and Prospects for Immunotherapy.
  Viruses. 2017 Sep 12;9(9). pii: E254.
• Smola S, Trimble C, Stern PL.
  Human papillomavirus-driven immune deviation: challenge and novel opportunity for immunotherapy.
  Ther Adv Vaccines. 2017 Jun;5(3):69-82.
• Smola S.
  RIPK3-a predictive marker for personalized immunotherapy?
  OncoImmunology 2016;5:e1075695.

Links

Zentrum für Human- und Molekularbiologie (ZHMB)
Universität des Saarlandes