Medizinische Fakultät der Universität des Saarlandes
Sie befinden sich hier: >> Startseite >> Forschung >> GK 1326 - Calcium >> Publications

Publications - Students of the GK1326


Pérez-Gómez A, Bleymehl K, Stein B, Pyrski M, Birnbaumer L, Munger SD, Leinders-Zufall T, Zufall F, Chamero P (2015). Innate predator odor aversion driven by parallel olfactory subsystems that converge in the ventromedial hypothalamus. Curr Biol. 25, 1340 – 1346

Schorr, S., Klein, M.-C., Gamayun, I., Melnyk, A., Jung, M., Schäuble, N., Wang, Q., Hemmis, B., Bochen, F., Greiner, M., Lampel, P., Urban, S. K., Haßdenteufel, S., Dudek, J., Chen, X.-Z., Wagner, R., Cavalié, A. und Zimmermann, R. (2015). Co-chaperone specificity in gating of the polypeptide conducting channel in the membrane of the human endoplamic reticulum, J. Biol. Chem. 290, 18621-18635.

Marshall MR, Pattu V, Halimani M, Maier-Peuschel M, Müller ML, Becherer U, Hong W, Hoth M, Tschernig T, Bryceson YT, Rettig J. (2015). VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity. J Cell Biol 210, 135-151.

Tóth BI, Konrad M, Ghosh D, Mohr F, Halaszovich CR, Leitner MG, Vriens J, Oberwinkler J, Voets T. (2015). Regulation of the transient receptor potential channel TRPM3 by phosphoinositides. J Gen Physiol. Jul; 146(1):51-63.

Schneider FM, Mohr F, Behrendt M, Oberwinkler J. (2015) Properties and functions of TRPM1 channels in the dendritic tips of retinal ON-bipolar cells. Eur J Cell Biol. Jul-Sep;94(7-9):420-7. Review

Kaestner, L., Tian, Q., Kaiser, E., Xian, W., Müller, A., Oberhofer, M., Ruppenthal, S., Sinnecker, D., Tsutsui, H., Miyawaki, A., Moretti, A., Lipp, P. (2015). Genetically encoded voltage indicators in circulation research. Int. J. Mol. Sci., 16, accepted for publication

Yang R, Pfütze K, Zucknick M, Sutter C, Wappenschmidt B, Marme F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B. (2015). DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood. Int J Cancer 136(8):1845-55.

Law JK, Susloparova A, Vu XT, Zhou X, Hempel F, Qu B, Hoth M, Ingebrandt S. (2015). Human T cells monitored by impedance spectrometry using field-effect transistor arrays: a novel tool for single-celladhesion and migration studies. Biosens Bioelectron 67:170-6.

Camacho Londoño,J.E., Tian,Q., Hammer,K., Schröder,L., Camacho Londoño,J., Reil,J., He,T., Oberhofer,M., Mannebach,S., Mathar,I., Philipp,S.E., Tabellion,W., Schweda,F., Dietrich,A., Kaestner,L., Laufs,U., Birnbaumer,L., Flockerzi,V., Freichel,M., Lipp,P. (2015). A background Ca2+ Entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling. Eur Heart J. published online: 11 Juni 2015

Miederer AM*, Alansary D*, Schwär G, Lee P, Jung M, Helms V, Niemeyer BA (2015). A novel splice variant antagonizes stromal interaction molecule (STIM) mediated Ca2+ signaling. Nature Comm. 6: 6899.

Alansary D, Bogeski I, Niemeyer BA (2015). Facilitation of Orai3 targeting and store-operated function by Orai1. Biochim Biophys Acta.; 1853(7):1541-50.


Oboti L, Pérez-Gomez A, Keller M, Jacobi E, Birnbaumer L, Leinders-Zufall T, Zufall F und Chamero P (2014.) A wide range of pheromone stimulated sexual and reproductive behaviors in female mice depend on G protein Gαo. BMC Biology 12:31

Synofzik, M., Haack, T. B., Kopajtich, R., Gorza, M., Rapoport, D., Greiner, M., Schönfeld, C., Freiberg, C., Schorr, S., Holl, R. W., Gonzalez, M. A., Fritsche, A., Fallier-Becker, P.,, Zimmermann, R., Strom, T. M., Meitinger, T., Züchner, S., Schüle, R., Schöls, L., Prokisch, H. (2014). Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegeneration. Am. J. Hum. Gen. 95, 689-697.

Rizwana Anjum R, Hiresh Ayoubian, and Frank Schmitz; Differential synaptic distribution of the scaffold proteins Cask and Caskin1 in the bovine retina. Molecular Cellular Neuroscience 62:19-21

Drews A, Mohr F, Rizun O, Wagner TF, Dembla S, Rudolph S, Lambert S, Konrad M, Philipp SE, Behrendt M, Marchais-Oberwinkler S, Covey DF, Oberwinkler J.(2014). Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels. Br J Pharmacol.171(4):1019-32.

Hui, X., Kaestner, L., Lipp, P. (2014) Differential targeting of cPKC and nPKC decodes and regulates Ca2+ and lipid signaling. Biochemical Society Transactions, 42(6), 1538-1542.

Kaestner, L., Scholz, A., Tian, Q., Ruppenthal, S.,Tabellion, W., Wiesen, K., Katus, H.A., Müller, O.J., Kotlikoff, M.I., Lipp, P. (2014) Genetically encoded Ca2+ indicators in cardiac myocytes. Circulation Research, 114, 1623-1639.

Hui, X., Reither, G., Kaestner, L., Lipp, P. (2014) Targeted activation of conventional and novel protein kinase C through differential translocation patterns. Molecular Cellular Biology, 34, 2370-2381.

Lipp, P., Hui, X., Reither, G., Kaestner, L. (2014) Multi-channel imaging of cellular signaling: Interplay of Ca2+ and conventional protein kinase C. Cold Spring Harb. Protoc., 11, 1180-1183.

Hammer, K., Lipp, P., Kaestner, L. (2014) Multi-beam 2-photon imaging of fast Ca2+ signals in Langendorff mice heart. Cold Spring Harb. Protoc., 11, 1175-1179.

Freichel M, Tsvilovskyy V, Camacho-Londoño JE. (2014) TRPC4- and TRPC4-containing channels.

Handb Exp Pharmacol. 222:85-128,


Mathar I, Kecskes M, Van der Mieren G, Jacobs G, Camacho Londoño JE, Uhl S, Flockerzi V, Voets T, Freichel M, Nilius B, Herijgers P, Vennekens R.(2014) Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice. Circ Res. 114(2):283-94,

Uhl S, Mathar I, Vennekens R, Freichel M. (2014) Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice. J Mol Cell Cardiol. 74:307-17,

Drews, A., Mohr,F., Rizun,O, Wagner,T.F.J., Dembla, S., Rudolph, S., Lambert,L., Konrad,M., Behrendt, M., Philipp, S.E., Marchais-Oberwinkler,S., CoveyD.F., Oberwinkler,J. (2014) Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels. Br. J. Pharmacol. 171, 1019-1032

Sell TS, Belkacemi T, Flockerzi V, Beck A. (2014). Protonophore properties of hyperforin are essential for its pharmacological activity. Sci. Rep. 10.1038/srep07500.

Hugo S, Dembla E, Halimani M, Matti U, Rettig J, Becherer U (2013) Deciphering dead-end docking of large dense core vesicles in bovine chromaffin cells. J Neurosci 33, 17123-17137

Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, Moghadam PK, Bost A, Schirra C, Rettig J, Reim K, Brose N, Mohrmann R, Bruns D (2014) Complexin synchronizes primed vescicle exocytosis and regulates fusion por dyanmis, J Cell Biol. 2014; 204(7):1123-40.PMID: 24687280

Halimani M, Pattu V, Marshall MR, Chang HF, Matti U, Jung M, Becherer U, Krause E, Hoth M, Schwarz EC, Rettig J. 2014. Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes. Eur J Immunol, 44(2), 573-84.

Kummerow C, Schwarz EC, Bufe B, Zufall F, Hoth M, Qu B. (2014). A simple, economic, time-resolved killing assay. Eur J Immunol doi: 10.1002/eji.201444518. [Epub ahead of print].

Mayur Dembla, Silke Wahl, Rashmi Katiyar, and Frank Schmitz (2014) ArfGAP3 is a component of the photoreceptor synaptic ribbon complex and forms a NAD(H)-regulated, redox-sensitive complex with RIBEYE that is important for endocytosis The Journal of Neuroscience, 34(15):5245-5260

Schäuble, N., Cavalié, A., Zimmermann, R. und Jung, M. (2014) „Interaction of Pseudomonas aeruginosa Exotoxin A with the human Sec61 complex suppresses passive calcium efflux from the endoplasmic reticulum“, Channels, DOI:

*Pfeffer, S., *Dudek, J., Gogala, M., Schorr, S., Linxweiler, J., Lang, S., Becker, T., Beckmann, R., Zimmermann, R. und Förster, F. (2014) "Structure of the mammalian oligosaccharyl-transferase in the native ER protein translocon", Nature Comm. Doi: 10.1038/ncomms4072. *equal contribution

Alansary D*, Kilch T*, Holzmann C, Peinelt C, Hoth M, and Lis A. (2014). Patch-Clamp Measurement of ICRAC and ORAI Channel Activity. Cold Spring Harbor Protocols. pp. 277-282

Alansary D*, Kilch T*, Holzmann C, Peinelt C, Hoth M, and Lis A. (2014). The Minimal Requirements to Use Calcium Imaging to Analyze ICRAC. Cold Spring Harbor Protocols. pp. 291-295

Alansary D*, Kilch T*, Holzmann C, Peinelt C, Hoth M, and Lis A. (2014). Measuring Endogenous ICRAC and ORAI Currents with the Patch-Clamp Technique. Cold Spring Harbor Protocols. pp. 283-290


Harper,M.T., Camacho Londoño,J.E., Quick,K., Camacho Londoño,J., Philipp,S.E., Birnbaumer,L., Freichel,M., Poole,A.W. (2013). Coincident stimulation activates canonical transient receptor potential channels in platelets. Science signaling 6, ra50.

Matti U, Pattu V, Halimani M, Schirra C, Krause E, Liu Y, Weins L, Chang HF, Guzman R, Olausson J, Freichel M, Schmitz F, Pasche M, Becherer U, Bruns D, Rettig J (2013). Synaptobrevin2 is the v-SNARE required for cytotoxic T lymphocyte lytic granule fusion. Nat. Commun. 4, 1439.

Yao W, Cai X, Liu C, Qin Y, Cheng H, Ji S, Xu W, Wu C, Chen T, Xu J, Long J, Fang Z, Qu B, Hoth M, Ni Q, Zha X, Yu X. 2013. Profilin1 potentiates apoptosis induced by staurosporine in cancer cells. Curr Mol Med. 13, 417-428.

Schwarz EC, Qu B, and Hoth M. (2012). Calcium, cancer and killing: The role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells. Biochim Biophys Acta. 1833: 1603-1611.

Shaw PJ*, Qu B*, Hoth M, Feske S. (2013). Molecular regulation of CRAC channels and their role in lymphocyte function. Cell Mol Life Sci 70, 2637-56. * These authors contributed equally to this work

Wahl S, Katiyar R, Schmitz F (2013). A local, periactive zone endocytotic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. The Journal of Neuroscience,(2013) June 19;33(25)10278-10300 April 9, 2014.34(15):5245-5260

*Linxweiler, M., *Schorr, S., Jung, M., Schäuble, N., Linxweiler, J., Langer, F., Schäfers, H.-J., Cavalié, A., Zimmermann, R. und Greiner, M. (2013) Targeting cell migration and the ER stress response with calmodulin antagonists: A clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells, BMC – cancer 13, 574.

*equal contribution

Dudek, J., Lang, S., Schorr, S., Linxweiler, J., Greiner, M. und Zimmermann, R. (2013) Analysis of protein translocation into the endoplasmic reticulum of mammalian cells, in Methods in Molecular Biology 1033 (Herrmann, J. and Rapaport, D., eds), Humana Press, New York, USA, 285-299.

Wang J, Wagner-Britz L, Bogdanova A, Ruppenthal S, Wiesen K, Kaiser E, Tian Q, Krause E, Bernhardt I, Lipp P, Philipp SE, Kaestner L., Morphologically homogeneous red blood cells present a heterogeneous response to hormonal stimulation. PLoS One. 2013 Jun 28;8(6):e67697. doi: 10.1371/journal.pone.0067697. Print 2013.

Herrmann S, Lipp P, Wiesen K, Stieber J, Nguyen H, Kaiser E, Ludwig A., The cardiac sodium-calcium exchanger NCX1 is a key player in the initiation and maintenance of a stable heart rhythm. Cardiovasc Res. 2013 Sep 1;99(4):780-8. doi: 10.1093/cvr/cvt154. Epub 2013 Jun 12.PMID:23761399

Kilch T, Alansary D*, Peglow M, Dörr K, Rychkov G, Rieger H, Peinelt C, Niemeyer BA (2013)

Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1.

J Biol Chem. 2013 Jan 18; 288(3):1653-64 (*equal contribution 1st author, name now without hyphen due to passport reasons)

Bost A, Pasche M, Schirra C, Becherer U (2013) Super-resolution microscopy in studying neuroendocrine cell function. Front Neurosci 7, 222.

Hugo S, Dembla E, Halimani M, Matti U, Rettig J, Becherer U (2013) Deciphering dead-end docking of large dense core vesicles in bovine chromaffin cells. J Neurosci 33, 17123-17137


Borisovska M, Schwarz Y, Dhara M, Yarzagaray A, Hugo S, Narzi D, Siu S, Kesavan J, Mohrmann R, Böckmann R, Bruns D, Membrane-proximal tryptophans of synaptobrevinII stabilize priming of secretory vesicles. (2012) J. Neurosci. 32(45),15983-97

Pattu V.*, Qu B.*,, Schwarz EC, Strauss B, Weins L, Bhat SS , Halimani M, Marshall M, Rettig J, and Hoth M.( 2012). SNARE protein expression and localization in human cytotoxic T lymphocytes. Eur J Immunol 42: 470-475. * These authors contributed equally to this work

Schmitz FNatarajan S, Venkatesan JK, Wahl S, Schwarz K, Grabner CP.

EF hand-mediated Ca and cGMP signaling in photoreceptor synaptic terminals

Front Mol Neurosci. (2012);5:26. Epub 2012 Feb 29.

*Schäuble, N., *Lang, S., Jung, M., Cappel, S., Schorr, S., Ulucan, Ö., Linxweiler, J., Dudek, J., Blum, R., Helms, V., Paton, A. W., Paton, J. C., Cavalié, A. und Zimmermann, R. (2012) "BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER", EMBO J. 31, 3282-3296.

*equal contribution,

Lang, S., Benedix, J., Fedeles, S. V., Schorr, S., Schirra, C., Schäuble, N., Jalal, C., Greiner, M., Haßdenteufel, S., Tatzelt, J., Kreutzer, B., Edelmann, L., Krause, E., Rettig, J., Somlo, S., Zimmermann, R. und Dudek, J. (2012) "Different effects of Sec61a-, Sec62 and Sec63-depletion on transport of polypeptides into the endoplasmic reticulum of mammalian  cells", J. Cell Sci. 125, 1958-1969.

Frühwald,J., Camacho Londoño, J., Dembla,S., Mannebach,S., Lis,A., Drews,A., Wissenbach,U., Oberwinkler,J., Philipp,S.E. (2012) Alternative splicing of a protein domain indispensable for function of transient receptor potential melastatin 3 (TRPM3) channels. J. Biol. Chem. 287, 36663-36672.

Rothenbusch, U., Sawatzki, M., Chang, Y., Caesar, S. and Schlenstedt, G. (2012) Sumoylation regulates Kap114-mediated nuclear transport. EMBO J. 31, 2461-2472.

Pasche M, Matti U, Hof D, Rettig J, Becherer U (2012) Docking of LDCVs Is Modulated by Lower Intracellular [Ca2+] than Priming. PLoS One 7, e36416.

Rothenbusch, U., Sawatzki, M., Chang, Y., Caesar, S. and Schlenstedt, G. (2012) Sumoylation regulates Kap114-mediated nuclear transport. EMBO J. 31, 2461-2472.


Qu* B, Al-Ansary* D, Kummerow C, Hoth M, Schwarz EC. (2011). ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance, Cell Calcium 50: 261-269.

Qu* B, Pattu* V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, Rieger H, Rettig J, Hoth M. (2011). Docking of Lytic Granules at the Immunological Synapse in Human CTL Requires Vti1b-Dependent Pairing with CD3 Endosomes. J Immunol 186 (12): 6894-6904. * These authors contributed equally to this work

Pattu* V, Qu* B, Marshall M, Becherer U, Junker C, Matti U, Schwarz EC, Krause E, Hoth M, Rettig J. (2011). Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes. Traffic 12 (7): 890-901.

These authors contributed equally to this work

Schwarz K*, Natarajan S*, Kassas N, Vitale N, Schmitz F. (2011) The Synaptic Ribbon Is a Site of Phosphatidic Acid Generation in Ribbon Synapses J. Neurosci., 31(44): 15996-16011. * gleichberechtigte Erstautoren.

Lang, S., Schäuble, N., Cavalié, A. und Zimmermann, R. (2011)

Live cell calcium imaging in combination with siRNA mediated gene silencing identifies Ca2+ leak channels in the ER membrane and their regulatory mechanisms.

J. Visualized Experiments DOI: 10.3791/2730.

Weiss J, Pyrski M, Jacobi E, Bufe B, Willnecker V, Schick B, Zizzari P, Gossage SJ, Greer CA, Leinders-Zufall T, Woods G, Wood JN, Zufall F (2011)Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.

Nature 472, 186 – 190

Heart Rate Contributes to the Vascular Effects of Chronic Mental Stress: Effects on Endothelial Function and Ischemic Brain Injury in Mice.“

Custodis F, Gertz K, Balkaya M, Prinz V, Mathar I, Stamm C, Kronenberg G, Kazakov A, Freichel M, Böhm M, Endres M, Laufs U. Stroke 2011 Apr 28.

Moderate Calcium Channel Dysfunction in Adult Mice with Inducible Cardiomyocyte-specific Excision of the cacnb2 Gene.“

Meissner M*, Weissgerber P*, Londoño JE*, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V. J Biol Chem. 286: 15875-82 (2011). * equal contribution

Quintana A., Pasche M., Junker C., Al-Ansary D., Nuñez L, Villalobos C., Niemeyer B.A., Becherer U., Rettig J. & Hoth M. Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate localcalcium signals for T-cell activation. EMBO J 2011; 30(19):3895-912. (2011).


Guzman R.E., Schwarz Y.N., Rettig J., and Bruns, D. (2010) SNARE force synchronizes synaptic vesicle fusion and controls the kinetics of quantal synaptic transmission. J Neurosci 30, 10272-81.

Bogeski I, Al-Ansary D, Qu B, Niemeyer BA, Hoth M, Peinelt C (2010).

Pharmacology of ORAI channels as a tool to understand their physiological functions.

Expert Reviews of Clinical Pharmacology 3: 291-303.

Venkatesan J.K.*, Natarajan S.*, Schwarz K.*, Mayer S.I., Alpadi K., Magupalli V.G. Sung C.-H., Schmitz F. (2010) NAD(H)-dependent binding of the neuronal Ca2+-sensor protein GCAP2 to photoreceptor synaptic ribbons.

J. Neurosci., (2010) May 12;30(19):6559-76.* gleichberechtigte Erstautoren.

*Erdmann, F., *Schäuble, N., Lang, S., Jung, M., Honigmann, A., Ahmad, M., Benedix, J., Dudek, J., Kopp, A., Helms, V., Cavalié, A., Wagner, R. und Zimmermann, R. (2010)

"Interaction of calmodulin with Sec61a limits Ca2+ leakage from the endoplasmic reticulum",

EMBO J. 30, 17-31. DOI: EMBOJ-2010-74877. *equal contribution

Benedix, J., Lajoie, P., Jaiswal, H., Burgard, C., Greiner, M., Zimmermann, R., Rospert, S., Snapp, E. L. und Dudek, J. (2010) BiP modulates the affinity of its co-chaperone ERj1 to ribosomes,

J. Biol. Chem. 285, 36427-36433. DOI: 10.1074/jbc.M110.143263.

Chang, Y., Schlenstedt, G., Flockerzi, V. and Beck, A. (2010)

Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1.

FEBS Lett. 584, 2028-2032

Mathar, I., Vennekens, R., Meissner, M., Kees, F., Van der Mieren, G., J.E. Camacho-Londono, Uhl, S., Voets, T., Hummel, B., Herijgers, P., Nilius, B., Flockerzi, V., Schweda, F., Freichel, M.

„Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice”

Journal of Clinical Investigation, 120: 3267-79 (2010).

Klaiber M, Kruse M, Völker K, Schröter J, Feil R, Freichel M, Gerling A, Feil S, Dietrich A, Londoño JE, Baba HA, Abramowitz J, Birnbaumer L, Penninger JM, Pongs O, Kuhn M.

Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.”

Basic Res Cardiol. 105: 583-95 (2010)

Bogeski I, Kummerow C, Al-Ansary D*, Schwarz EC, Koehler R, Kozai D, Takahashi N, Peinelt C, Griesemer D, Bozem M, Mori Y, Hoth M, Niemeyer BA (2010)

Differential Redox Regulation of ORAI Ion Channels: A Mechanism to Tune Cellular Calcium Signaling.

Sci Signal 3: ra27 (*equal contribution 2nd author)


Gross,S.A., Guzmán G.A., Wissenbach, U.,Philipp, S.E.,  Zhu M.X., Bruns, D., Cavalié,A. JBC (2009) TRCP5 is a Ca 2+-Avtivated channel functionally coupled to Ca 2+ - Selective Ion Channels. J Biol Chem 284, 34423-32.

Dudek J, Benedix J, Cappel S, Greiner M, Jalal C, Müller L, Zimmermann R (2009)

Functions and pathologies of BiP and its interaction partners.

Cell. Mol. Life Sci. 65, 1556-1569.

Zahedi R. P., Völzing C., Schmitt A., Frien M., Jung M., Dudek J., Wortelkamp S., Sickmann A. und Zimmermann R. (2009).

Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7,

Proteomics 9, 3463-3473.

Luccardini C., Yakovlev A.V., Pasche M., Gaillard S., Li D., Rousseau F., Ly R., Becherer U., Mallet J.M., Feltz A., Oheim M. (2009). Measuring mitochondrial and cytoplasmic Ca2+ in EGFP expressing cells with a low-affinity calcium Ruby and its dextran conjugate. Cell Calcium 45, 275-83.


Magupalli, V.G., Schwarz, K., Alpadi, K., Natarajan, S., Seigel, G.M., Schmitz, F. (2008) Multiple RIBEYE - RIBEYE interactions create a dynamic scaffold for the formation of synaptic ribbons.

J. Neurosci. 28, 7954-7967 (2008).

Wagner T.F., Loch S., Lambert S., Straub I., Mannebach S., Mathar I., Dufer M., Lis A., Flockerzi V., Philipp S.E., Oberwinkler J. (2008). Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells.

Nat Cell Biol 10, 1421-1430.


Kesavan J., Borisovska M. and Bruns D. (2007).

v-SNARE actions during Ca2+- triggered exocytosis. Cell 131, 351-363.

Wissenbach U., Philipp S. E., Gross S. A., Cavalié A., Flockerzi V. (2007).

Primary structure, chromosomal localization and expression in immune cells of the murine

ORAI and STIM genes. Cell Calcium 42, 439 – 46.

Cheng H., Beck A., Launay P., Gross S. A., Stokes A. J., Kinet J. P., Fleig A., Penner R. (2007).

TRPM4 controls insulin secretion in pancreatic beta-cells. Cell Calcium 41, 51 – 61.

Gross S. A., Wissenbach U., Philipp S. E., Freichel M., Cavalié A., Flockerzi V. (2007)

Murine ORAI2 splice variants form functional CRAC channels.

J. Biol. Chem. 282,19375-19384.

Becherer U., Pasche M., Nofal S., Hof D., Matti U., Rettig J. (2007)

Quantifying exocytosis by combination of membrane capacitance measurements and total internal reflection fluorescence microscopy in chromaffin cells. PLoS One 2:e505.

Zeniou-Meyer M., Liu Y., Begle A., Olanish M., Hanauer A., Becherer U., Rettig J., Bader M.F., Vitale N.

The Coffin-Lowry syndrome-associated protein RSK2 is implicated in calcium-regulated exocytosis through the regulation of PLD1. Proc. Natl. Acad. Sci. 105, 8434-8439.

Vennekens R., Olausson J., Meissner M., Bloch W., Mathar I., Philipp S.E., Schmitz F., Weissgerber P., Nilius B., Flockerzi V., Freichel M., (2007).

Increased IgEdependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nat Immunol 8, 312-320.


Erler I., Al-Ansary D, Wissenbach U, Wagner TF, Flockerzi V and Niemeyer BA( 2006).

Trafficking and assembly of the cold-sensitive TRPM8 channel.

J Biol Chem 281, 38396-404. equal contribution