Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Institut für Medizinische Mikrobiologie und Hygiene
Leitung: Prof. Dr. Dr. Sören Becker
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Original Paper

(bold, authors of the Institute of Medical Microbiology and Hygiene, University of Saarland)

 


2020

Maikranz E, Spengler C, Thewes N, Thewes A, Nolle F, Jung P, Bischoff M, Santen L, Jacobs K. Different binding mechanisms of Staphylococcus aureus to hydrophobic and hydrophilic surfaces. Nanoscale (accepted for publication)

 

Thurner L, Hartmann S, Bewarder M, Fadle N, Regitz E, Schormann C, Quiroga N, Kemele M, Klapper W, Rosenwald A, Trümper L, Bohle RM, Nimmesgern A, Körbel C, Laschke MW, Menger MD, Barth S, Kubuschok B, Mottok A, Kaddu-Mulindwa D, Hansmann ML, Pöschel V, Held G, Murawski N, Stilgenbauer S, Neumann F, Preuss KD, Pfreundschuh M. Identification of the atypically modified autoantigen Ars2 as the target of B-cell receptors from activated B cell-type diffuse large B-cell lymphoma. Haematologica. (published online ahead of print)


Lohse S, Pfuhl T, Berkó-Göttel B, Gärtner B, Becker SL, Schneitler S, Smola S. Challenges and issues of SARS-CoV-2 pool testing - Authors' reply. Lancet Infect Dis. (published online ahead of print)

 

Mang S, Kaddu-Mulindwa D, Metz C, Becker A, Seiler F, Smola S, Maßmann A, Becker SL, Papan C, Bals R, Lepper PM, Danziger G. Pneumocystis Jirovecii Pneumonia and SARS-CoV-2 Co-Infection in newly diagnosed HIV-1 infection. Clin Infect Dis. (published online ahead of print)

 

Konstantinović J, Yahiaoui S, Alhayek A, Haupenthal J, Schönauer E, Andreas A, Kany AM, Mueller R, Köhnke J, Berger F, Bischoff M, Hartmann RW, Brandstetter H, Hirsch AKH. N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases. J Med Chem. (accepted for publication)

 

Mawlood DA, Becker SL, Vogt T, Müller CSL. Kikuchi-Fujimoto disease triggered by systemic lupus erythematosus and Mycoplasma pneumoniae infection – report of a case and review of the literature. American Journal of Dermatopathology (accepted for publication)

 

Alhussein F, Fürstenberg J, Gaupp R, Eisenbeis J, Last K, Becker SL, Papan C. Human infections caused by Staphylococcus argenteus in Germany: genetic characterisation and clinical implications of novel species designation. Eur J Clin Microbiol Infect Dis. (published online ahead of print)

 

Becker SL. WGS for infection prevention and control in Africa. Lancet Microbe (accepted for publication)

 

Lohse S, Pfuhl T, Berkó-Göttel B, Rissland J, Geißler T, Gärtner B, Becker SL, Schneitler S, Smola S (2020). Pooling of samples for testing for SARS-CoV-2 in asymptomatic people. Lancet Infect Dis. (published online ahead of print)

 

Papan C, Langer F, Bittenbring JT, Bohle RM, Schäfers HJ, Fries P, Becker SL. A 71-year-old man with chest pain and a slowly progressive pulmonary mass. Chest (published online ahead of print)

 

Breitbart P, Meister S, Meyer T, Gärtner BC. Incidence and prevalence of Borrelia burgdorferi antibodies in male professional football players. Clin J Sport Med (Epub ahaed of print)

 

Stenger T, Ledo A, Ziller C, Schub D, Schmidt T, Enders M, Gärtner BC, Sester M, Meyer T. Timing of Vaccination after Training: Immune Response and Side Effects in Athletes. Med Sci Sports Exerc. [Epub ahead of print]

 

Kridaningsih TN, Sukmana DJ, Mufidah H, Diptyanusa A, Kusumasari RA, Burdam FH, Kenangalem E, Poespoprodjo JR, Fuad A, Mahendradhata Y, Supargiyono S, Utzinger J, Becker SL, Murhandarwati EEH. Epidemiology and risk factors of human Strongyloides stercoralis infection in Papua, Indonesia: a molecular diagnostic study. Acta Tropica 209:105575

 

Thurner L, Hartmann S, Fadle N, Regitz E, Kemele M, Kim YJ, Bohle RM, Nimmesgern A, von Müller L, Kempf VAJ, Weniger MA, Neumann F, Schneider N, Vornanen M, Sundström C, de Leval L, Engert A, Eichenauer DA, Küppers R, Preuss KD, Hansmann ML, Pfreundschuh M. Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma. Nat Commun. 11:2465.

 

Meyer S, Nüßlein T, Nährlich L, Bend J, Gärtner B, Becker SL, Simon A. Infection prevention and control in patients with cystic fibrosis (CF): results from a survey in 35 German CF treatment centers. J of Cyst Fibrosis 19:384-387.

 

Kaddu-Mulindwa D, Roth S, Klees-Rollmann A, Fassbender K, Fousse M. Primary HIV infection presenting with Kaposi sarcoma and limbic encephalitis.  J Neurovirol. 26:292-296

 

Abdulnasser Harfoush S, Hannig M, Le DD, Heck S, Leitner M, Omlor AJ, Tavernaro I, Kraegeloh A, Kautenburger R, Kickelbick G, Beilhack A, Bischoff M, Nguyen J, Sester M, Bals R, Dinh QT. High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice. Respir Res. 21:168.

 

Gaidar D, Jonas A, Akulenko R, Ruffing U, Herrmann M, Helms V, von Müller L. Analysis of the dynamics of Staphylococcus aureus binding to white blood cells using whole blood assay and geno-to-pheno mapping. Int J Med Microbiol. 310:151411.

 

Karaoui WR, Rustom LBO, Bou Daher H, Rimmani HH, Rasheed SS, Matar GM, Mahfouz R, Araj GF, Zahreddine N, Kanj SS, Berger FK, Gärtner B, El Sabbagh R, Sharara AI. Incidence, outcome, and risk factors for recurrence of nosocomial Clostridioides difficile infection in adults: A prospective cohort study. J Infect Public Health. 13:485-490

 

Davies K, Davis G, Barbut F, Eckert C, Petrosillo N, Pisapia R, Gärtner B, Berger FK, Reigadas E, Bouza E, Demont C, Wilcox MH. Factors affecting reported Clostridioides difficile infection rates; the more you look the more you find, but should you believe what you see? Anaerobe 62:102178.

 

Berger FK, Mellmann A, Bischoff M, von Müller L, Becker SL, Simango C, Gärtner BC (2020). Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe. Int J Infect Dis. 96:82-87.

 

Leuer L, Krill A, Wilkens H, Wagenpfeil G, Bischoff M, Meier C, Bals R, Tschernig T. The phagocytosis of blood leukocytes from cystic fibrosis patients is not impaired in general. Lung 198:235-239.

 

Nourkami-Tutdibi N, Linsler S, Yilmaz U, Pfeifer J, Derouet C, Becker SL, Zemlin M, Meyer S, Kulas P. A 6-year-old boy with a frontal mass: Pott’s puffy tumor. Journal of Pediatrics 217:211

 

Glebe D, van Bömmel F, Dudareva S, Gärtner B, Monazahian M, Roß S, Rösler J, Slanina H, Spickhoff A, Thanheiser M, Schüttler CG. Prävention der nosokomialen Übertragung von Hepatitis-B-Virus (HBV) und Hepatitis-C-Virus (HCV) durch im Gesundheitswesen Tätige : Empfehlungen der Deutschen Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) e. V. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 63:218-225.

 

Becker SL, Pérez Guerra N, Müller CSL. Persistent, highly pruritic nodular skin lesions in a traveler returning from Guyana. Travel Medicine and Infectious Disease 33:101552

 

Eichel V, Papan C, Boutin S, Pöschl J, Heeg K, Nurjadi D. Altering Antibiotic Regimen as Additional Control Measure in Suspected Multi-Drug-Resistant Enterobacter cloacae Outbreak in a Neonatal Intensive Care Unit. J Hosp Infect. 104:144-149

 

Müller L, Bischoff M, Tschernig T. UV-C Irradiation Reduces the Experimentally Induced Bacterial Load on the Surface of a Human Cadaver: An Additional Option for the Preservation of Cadavers in Anatomy. Clin Anat. 33:113-116.

 

Berger FK, Mellmann A, von Müller L, Bischoff M, Gärtner BC, on behalf of the German speaking C. difficile laboratory study group. Quality assurance for genotyping and resistance testing of Clostridium (Clostridioides) difficile isolates - Experiences from the first inter-laboratory ring trial in four German speaking countries. Anaerobe 61:102093

 

Ledo A, Schub D, Ziller C, Enders M, Stenger T, Gärtner BC, Schmidt T, Meyer T, Sester M. Elite athletes on regular training show more pronounced induction of vaccine-specific T-cells and antibodies after tetravalent influenza vaccination than controls. Brain Behav Immun. 83:135-145.

 

Anversa Dimer F, de Souza Carvalho-Wodarz C, Goes A, Cirnski K, Herrmann J, Schmitt V, Pätzold L, Abed N, De Rossi C, Bischoff M, Couvreur P, Müller R, Lehr CM. PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus. Nanomedicine 24:102125.

 

Müller-Schulte E, Nonfra Tuo M, Akoua-Koffi C, Schaumburg F, Becker SL. High prevalence of ESBL-producing Klebsiella pneumoniae in clinical samples from central Côte d’Ivoire. Int J Infect Dis. 91:207-209.

 

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2019

 

Haidar A, Awadelkareem A, Veziroglu S, Fiutowski J, Eichler H, Müller I, Kiefer K, Faupel F, Bischoff M, Veith M, Aktas OC, Abdul-Khaliq H. PTFEP–Al2O3 hybrid nanowires reducing thrombosis and biofouling. Nanoscale Adv. 1: 4659-4664.

 

Shi L, Stachon T, Latta L, Elhawy MI, Orosz E, Gunaratnam G, Kiderlein AF, Seitz B, Bischoff M, Szentmáry N. Comparison of in vitro assays to study the effectiveness of antiparasitics against Acanthamoeba castellani trophozoites and cysts. Acta Microbiol Immunol Hung. 13:1-10.

 

Zamani AH, Razmyar J, Berger FK, Kalidari GA, Jamshidi A. Isolation and toxin gene detection of Clostridium (Clostridioides) difficile from traditional and commercial quail farms and packed quail meat for market supply. Acta Veterinaria Hungarica 67:499–504.

 

Schneeberger PHH, Fuhrimann S, Becker SL, Pothier JF, Duffy B, Beuret C, Frey JE, Utzinger J (2019). Qualitative microbiome profiling along a wastewater system in Kampala, Uganda. Sci Rep 9:17334.

 

Gunaratnam G, Tuchscherr L, Elhawy MI, Bertram R, Eisenbeis J, Spengler C, Tschernig T,  Löffler B, Sommerville GA, Jacobs K, Herrmann M, Bischoff M. ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells. Sci Rep. 9:16267.

 

Spengler C, Nolle F, Mischo J, Faidt T, Grandthyll S, Thewes N, Koch M, Müller F, Bischoff M, Klatt MK, Jacobs K. Strength of bacterial adhesion on nanostructured surfaces quantified by substrate morphometry. Nanoscale 11:19713-19722.

 

Bufe B, Teuchert Y, Schmid A, Pyrski M, Pérez-Gómez A, Eisenbeis J, Timm T, Ishii T, Lochnit G, Bischoff M, Mombaerts P, Leinders-Zufall T, Zufall F. Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour. Nat Commun. 10:4889.

 

Benthien S, Schlüter C, Becker SL, Papan C. Detection of Bordetella trematum in a diabetic patient with a skin and soft tissue infection. Int J Infect Dis. 89:1-2

 

Papan C, Kremp L, Weiß C, Petzold A, Schroten H, Tenenbaum T. Infectious causes of peripheral facial nerve palsy in children-a retrospective cohort study with long-term follow-up. Eur J Clin Microbiol Infect Dis. 38:2177-2184.

 

Steck P, Ritzmann F, Honecker A, Vella G, Herr C, Gaupp R, Bischoff M, Speer T, Tschernig T, Bals R, Beisswenger C. IL-17RE/IL-17C mediate the recruitment of neutrophils during acute Streptococcus pneumoniae pneumonia. Infect Immun. 87:e00329-19.

 

Emele MF, Joppe FM, Riedel T, Overmann J, Rupnik M, Cooper P, Kusumawati RL, Berger FK, Laukien F, Zimmermann O, Bohne W, Groß U, Bader O, Zautner AE. Proteotyping of Clostridioides difficile as Alternate Typing Method to Ribotyping Is Able to Distinguish the Ribotypes RT027 and RT176 From Other Ribotypes. Front Microbiol. 10:2087.

 

Selb R, Visockaite V, Graf B, Hamprecht A, Hogarth M, Sedlacek L, Schwarz R, Idelevich EA, Becker SL, Held J, Roll C, McCormick-Smith I, Heckmann D, Gerkrath J, Han CO, Wilmes D, Rickerts V. Molecular typing and in vitro resistance of Cryptococcus neoformans clinical isolates cultivated in Germany between 2011 and 2017. Int J Med Microbiol 309:151336

 

Müller-Schulte E, Gärtner BC. Vaccinations during pregnancy: a call to sting into action. Future Microbiol 14:995-1006.

 

Papan C, Kremp L, Weiß C, Petzold A, Schroten H, Tenenbaum T. Infectious causes of peripheral facial nerve palsy in children – a retrospective cohort study with long-term follow-up. Eur J Clin Microbiol Infect Dis 38:2177-2184.

 

Last K, Papan C. Being a parent at ECCMID 2019. Clin Microbiol Infect 25:1159-1160.

 

Menina S, Eisenbeis J, Kamal MAM, Koch M, Bischoff M, Gordon S, Loretz B, Lehr CM. Bioinspired liposomes for oral delivery of Colistin to combat intracellular infections by Salmonella enterica. Adv Healthc Mater. e1900564.

 

Piepenbrock E, Stelzer Y, Berger F, Jazmati N. Changes in Clostridium (Clostridioides) difficile PCR-ribotype distribution and antimicrobial resistance in a German tertiary care hospital over the last 10 years. Curr Microbiol 2019 76:520-526.

 

Galata V, Laczny CC, Backes C, Hemmrich-Stanisak G, Schmolke S, Franke A, Meese E, Herrmann M, von Müller L, Plum A, Müller R, Stähler C, Posch AE, Keller A. Integrating culture-based antibiotic resistance profiles with whole-genome sequencing data for 11,087 clinical isolates. Genomics Proteomics Bioinformatics 17:169-182.


Fofana HKM, Schwarzkopf M, Doumbia MN, Saye R, Nimmesgern A, Landouré A, Traoré MS, Mertens P, Utzinger J, Sacko M, Becker SL. Prevalence of Giardia intestinalis Infection in Schistosomiasis-Endemic Areas in South-Central Mali. Trop Med Infect Dis. 4.

 

Boden KT, Pérez Guerra N, Szurman P, Simon A, Becker SL. Eosinophilia, iron deficiency anaemia and a subconjunctival worm in a girl from Cameroon. Travel Med Infect Dis. 29:84-85.

 

Kranz LM, Gärtner B, Michel A, Pawlita M, Waterboer T, Brenner N. Development and Validation of HIV-1 Multiplex Serology. J Immunol Methods. 466:47-51.

 

Brenner N, Mentzer AJ, Butt J, Braband KL, Michel A, Jeffery K, Klenerman P, Gärtner B, Schnitzler P, Hill A, Taylor G, Demontis MA, Guy E, Hadfield SJ, Almond R, Allen N, Pawlita M, Waterboer T. Validation of Multiplex Serology for human hepatitis viruses B and C, human T-lymphotropic virus 1 and Toxoplasma gondii. PLoS One. 14:e0210407.

 

Feucherolles M, Poppert S, Utzinger J, Becker SL (2019). MALDI-TOF mass spectrometry as diagnostic tool in veterinary and human helminthology: a systematic review. Parasit Vectors 12:245.


Becker SL, Lunardon LM (2019). Importierte Parasitosen als diagnostische Herausforderung für die klinische Mikrobiologie – Fallbeispiele aus dem Saarland. Mikrobiologe (accepted for publication)


Becker SL, Schlotthauer U, Schäfers HJ, Bals R, Trudzinski FC (2019). Epidemiology, clinical management, diagnosis and treatment of infections caused by Mycobacterium chimaera. Pneumologie 73:474-481.


Berger FK, Gfrörer S, Becker SL, Baldan R, Cirillo DM, Frentrup M, Steglich M, Engling P, Nübel U, Mellmann A, Bischoff M, Gärtner B, von Müller L (2019). Hospital outbreak due to Clostridium difficile ribotype 018 (RT018) in southern Germany. Int. J.  Med. Microbiol. 309:189-193.


Nourkami-Tutdibi N, Simon A, Fries P, Becker SL, Ecker P, Zemlin M, Meyer S (2019). A 5-year-old boy with a chronic cough caused by Echinococcus granulosus. Lancet 393:74.

 

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2018


Becker SL, Berger FK, Feldner SK, Karliova I, Haber M, Mellmann A, Schäfers HJ, Gärtner B (2018). Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018. Eurosurveillance 23:pii=1800540.

 

Enkelmann J, Bohmer M, Fingerle V, Siffczyk C, Werber D, Littmann M, Merbecks SS, Helmeke C, Schroeder S, Hell S, Schlotthauer U, Burckhardt F, Stark K, Schielke A, Wilking H (2018). Incidence of notified Lyme borreliosis in Germany, 2013-2017. Sci Rep 8:14976

 

Kristanti H, Meyanti F, Wijayanti MA, Mahendradhata Y, Polman K, Chappuis F, Utzinger J, Becker SL, Murhandarwati EEH. Diagnostic comparison of Baermann funnel, Koga agar plate culture and polymerase chain reaction for detection of human Strongyloides stercoralis infection in Maluku, Indonesia. Parasitol Res. 117:3229-3235.


Thurner L, Hartmann S, Fadle N, Kemele M, Bock T, Bewarder M, Regitz E, Neumann F, Nimmesgern A, von Müller L, Pott C, Kim YJ, Bohle RM, Wasik M, Schuster SJ, Hansmann ML, Preuss KD, Pfreundschuh M. LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting. Leukemia 33:148-158.


Tschudin-Sutter S, Kuijper EJ, Durovic A, Vehreschild MJGT, Barbut F, Eckert C, Fitzpatrick F, Hell M, Norèn T, O'Driscoll J, Coia J, Gastmeier P, von Müller L, Wilcox MH, Widmer AF; Committee. Guidance document for prevention of Clostridium difficile infection in acute healthcare settings. Clin Microbiol Infect 24:1051-1054.


Becker SL, Becker TK. Parasitic infections in the intensive care unit. Anaesth Intensive Care 46:546-548


Seugendo M, Janssen I, Lang V, Hasibuan I, Bohne W, Cooper P, Daniel R, Gunka K, Kusumawati RL, Mshana SE, von Müller L, Okamo B, Ortlepp JR, Overmann J, Riedel T, Rupnik M, Zimmermann O, Groß U. Prevalence and strain characterization of Clostridioides (Clostridium) difficile in representative regions of Germany, Ghana, Tanzania and Indonesia - A comparative multi-center cross-sectional study. Front Microbiol. 9:1843.

 

Gannoun-Zaki L, Pätzold L, Huc-Brandt S, Baronian G, Elhawy MI, Gaupp R, Martin M, Blanc-Potard AB, Letourneur F, Bischoff M, and Molle V. PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with Coronin-1A during infection. J Biol Chem 293:15569-15580.

 

Eisenbeis J, Saffarzadeh M, Peisker H, Jung P, Thewes N, Preissner KT, Herrmann M, Molle V, Geisbrecht BV, Jacobs K, Bischoff M. The Staphylococcus aureus Extracellular Adherence Protein Eap Is a DNA Binding Protein Capable of Blocking Neutrophil Extracellular Trap Formation. Front Cell Infect Microbiol. 8:235.


Becker SL, Liwanag HJ, Snyder JS, Akogun O, Belizario V Jr, Freeman MC, Gyorkos TW, Imtiaz R, Keiser J, Krolewiecki A, Levecke B, Mwandawiro C, Pullan RL, Addiss DG, Utzinger J. Toward the 2020 goal of soil-transmitted helminthiasis control and elimination. PLoS Negl Trop Dis. 12:e0006606.


Kazimoto T, Abdulla S, Bategereza L, Juma O, Mhimbira F, Weisser M, Utzinger J, von Müller L, Becker SL. Causative agents and antimicrobial resistance Patterns of human skin and soft tissue infections in Bagamoyo, Tanzania. Acta Trop. 186:102-106.


Widmann T, Sester U, Schmidt T, Gärtner BC, Schubert J, Pfreundschuh M, Sester M. Rapid reconstitution of CMV-specific T-cells after stem-cell transplantation. Eur J Haematol. 101:38-47.

 

Galata V, Backes C, Laczny CC, Hemmrich-Stanisak G, Li H, Smoot L, Posch A, Schmolke S, Bischoff M, von Müller L, Plum A, Franke A, Keller A. Comparing genome versus proteome based identification of clinical bacterial isolates. Brief Bioinform. 19:495-505.


Alabi A, Kazimoto T, Lebughe M, Vubil D, Phaku P, Mandomando I, Kern WV, Abdulla S, Mellmann A, Peitzmann L, Bischoff M, Peters G, Herrmann M, Grobusch MP, Schaumburg F, Rieg S. Management of superficial and deep-seeted Staphylococcus aures skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort. Infection. 46:395-404.


Fries FN, Pattmöller M, Seitz B, Berger F, Kampen H, Szentmáry N, Becker SL. Ophtalmomyiasis externa due to Oestrus ovis in a traveller returning from Greece. Travel Med Infect Dis. 23:101-102.


Becker SL, Zange S, Brockmeyer M, Grün U, Halfmann A. Rapid MALDI-TOF-based identification of Brucella melitensis from positive blood culture vials may prevent laboratory-acquired infections. J Hosp Infect. 100:117-119.


Lepper PM, Hörsch SI, Seiler F, Kamp A, Becker SL, Lensch C, Conzelmann LO, Haake H, Muellenbach RM, Bals R, Kredel M, Langer F, Wilkens H, Trudzinski FC. Precutaneous mechanical circulation support combined with extracorporeal membrane oxygenation (oxyRVAD) in secondary right heart failiure. ASAIO J 64:e64-e67


Becker SL, Halfmann A, Schilling L, Mawlood DA, Janssen E, Reischl U, Vogt T, Müller CS. Mycobacterium iranicum infection in a patient with fish tank granuloma: a first case report. Eur J Dermatol. 28:238-239.


Gärtner H, Müller CSL, Becker SL, Bozzato A. A different kind of wrestler's ear. HNO 66:559-561.


Schmit D, Le DD, Heck S, Bischoff M, Tschernig T, Herr C, Beisswenger C, Kobelt P, Lepper PM, Chung KF, Bals R, Dinh QT. Allergic airway inflammation induces migration of mast cell populations into the mouse airway. Cell Tissue Res. 369:331-340.


Berger F, Rasheed SS, Araj GF, Mahfouz R, Rimmani HH, Karaoui WR, Sharara AI, Dbaibo G, Becker SL, von Müller L, Bischoff M, Matar GM, Gärtner BC. Molecular characterization, Toxin detection and resistance testing of human clinical Clostridium difficile isolates from Lebanon. Int J Med Microbiol 308:358-363.


Simon A, Mock M, Graf N, von Müller L. Investigation of Clostridium difficile ribotypes in symptomatic patients of a German pediatric oncology center. Eur J Pediatr. 177:403-408.


Buder S, Dudareva S, Jansen K, Loenenbach A, Nikisins S, Sailer A, Guhl E, Kohl PK, Bremer V; GORENET study group (Halfmann A). Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance. BMC Infect Dis. 18:44


Schub D, Fousse M, Faßbender K, Gärtner BC, Sester U, Sester M, Schmidt T. CTLA-4- expression on VZV-specific T cells in CSF and blood is specifically increased in patients with VZV related central nervous system infections. Eur J Immunol. 48:151-160.

 

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2017


Schlotthauer U, Schulze-Röbbecke R. Vertikale und horizontale Präventionsstrategien. Krankenhaushyg up2date 12:379-394.


Trudzinski FC, Seiler F, Wilkens H, Metz C, Kamp A, Bals R, Gärtner BC, Lepper PM, Becker SL. Microbiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction. Int J Chron Obstruct Pulmon Dis.13:29-35.


Furtwängler R, Schlotthauer U, Gärtner BC, Graf N, Simon A. Nosocomial legionellosis and invasive aspergillosis in a child with T-lymphoblastic leukemia. Int J Hyg Environ Health. 220:900-905.


Witek K, Jawad Nasim M, Bischoff M, Gaupp R, Arsenyan P, Vasileva J, Marc MA, Olejarz A, Latacz G, Kiez-Kononowicz, Handzlik J, Jacob C. Seenazolinium salts as small molecule catalysts with high potency against ESKAPE bacterial pathogens. Molecules 22:2174


Mardal M, Bischoff M, Ibanez M, Ruffing U, Hernandez F, Meyer MR. Microbial biotransformation of five pyrrolidinophenone-type psychoactive substances in wastewater and a wastewater isolated Pseudomonas putida strain. Drug Test Anal. 9:1522-1536


van Ingen J, Kohl TA, Kranzer K, Hasse B, Keller PM, Katarzyna Szafrańska A, Hillemann D, Chand M, Schreiber PW, Sommerstein R, Berger C, Genoni M, Rüegg C, Troillet N, Widmer AF, Becker SL, Herrmann M, Eckmanns T, Haller S, Höller C, Debast SB, Wolfhagen MJ, Hopman J, Kluytmans J, Langelaar M, Notermans DW, Ten Oever J, van den Barselaar P, Vonk ABA, Vos MC, Ahmed N, Brown T, Crook D, Lamagni T, Phin N, Smith EG, Zambon M, Serr A, Götting T, Ebner W, Thürmer A, Utpatel C, Spröer C, Bunk B, Nübel U, Bloemberg GV, Böttger EC, Niemann S, Wagner D, Sax H. Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery. a molecular epidemiology study. Lancet Infect Dis. 17:1033-1041.


Becker SL, Mawlood DA, Janssen A, Heinricy L, Janssen E, Vogt T, Müller CSL. Multibacillary leprosy in a migrant from Afghanistan: A disease not to be forgotten. Travel Med Infect Dis. 19:66-67.


Becker SL, Fähndrich S, Trudzinski FC, Gärtner B, Langer F, Becker TK, Bals R, Lepper PM, Lensch C. Extracorporeal membrane oxygenation (ECMO) as salvage treatment for pulmonary Echinococcus granulosus infection with acute cyst ruture. Int J Infect Dis. 64:47-49.


Schlotthauer U, Trudzinski FC, Gärtner B, Lepper PM, Becker SL, Hennemann K. Desinfizierende Aufbereitung von ECMO-Thermoregulationsgeräten bei Nachweis von Mycobacterium chimaera. HygMed 42:123-126.


Toure FS, Kouame S, Tia H, Monemo P, Cisse A, Diane B, Becker SL, Akoua-Koffi C. Epidemiology of paediatric meningitis in central Cote d'Ivoire after the implementation of Haemophilus influencae type b vaccination. New Microbiol. 40:170-174.


Spengler C, Thewes N, Jung P, Bischoff M, Jacobs K. Determination of the nano-scaled contact area of staphylococcal cells. Nanoscale 9:10084-10093.


Vubil  D, Garrine M, Ruffing U, Acácio S, Sigaúque B, Alonso PL, von Müller L, Herrmann M, Mandomando I. Molecular characterization of Community acquired Staphylococcus aureus bacteremia in young children in Southern Mozambique, 2001–2009. Front Microbiol. 8:730.


Spengler C, Thewes N, Nolle F, Faidt T, Umanskaya N, Hannig M, Bischoff M, Jacobs K. Enhanced adhesion of Streptococcus mutans to hydroxyapatite after exposure to saliva. J Mol Recognit. 30:e2615.


Shalabi A, Ehrlich T, Schäfers HJ, Becker SL. Infective endocarditis caused by Pseudomonas stutzeri in a patient with Marfan syndrome: Case report and brief literature review. IDCases 10:22-25.


Bischoff M, Wonnenberg B, Nippe N, Nyffenegger-Jann N, Voss M, Beisswenger C, Sunderkötter C, Virginie Molle V, Dinh TQ, Lammert F, Bals R, Herrmann M, Somerville G, Tschernig T, Gaupp R. CcpA affects infectivity of Staphylococcus aureus in a hyperglycemic environment. Front Cell Infect Microbiol. 7:172.


Becker SL, Müller I, Mertens P, Herrmann M, Zondie L, Beyleveld L, Gerber M, du Randt R, Pühse U, Walter C, Utzinger J. PCR-based verification of positive rapid diagnostic test for intestinal protozoa infections with variable test band intensities. Acta Trop. 174:49-55.


Wu MF, Deichelbohrer M, Tschernig T, Laschke MW, Szentmary N, Hüttenberger D, Foth HJ, Seitz B, Bischoff M. Chlorin e6 mediated photodynamic inactivation for multidrug resistant Pseudomonas aeruginosa keratitis in mice in vivo. Sci. Rep. 7:44537.


Ruffing U, Alabi A, Kazimoto T, Vubil DC, Akulenko R, Abdulla S, Alonso P, Bischoff M, Germann A, Grobusch MP, Helms V, Hoffmann J, Kern WV, Kremsner PG, Mandomando I, Mellmann A, Peters G, Schaumburg F, Schubert S, Strauß L, Tanner M, Briesen HV, Wende L, Müller LV, Herrmann M. Community-associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A cross-sectional geographic correlation study. Sci Rep. 7:154.


Eisenbeis J, Peisker H, Backes CS, Bur S, Hölters S, Thewes N, Greiner M, Junker C, Schwarz EC,  Hoth M,  Junker K, Preissner KT, Jacobs K, Herrmann MBischoff M. The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and Migration repressing factor that alters the cell morphology of keratinocytes. Int J Med Microbiol. 307:116-125.


Färber J, Illiger S, Berger F, Gärtner BC, von Müller L, Lohmann CH, Bauer K, Grabau C, Zibolka S, Schlüter D, Geginat G. Management of a cluster of Clostridium difficile infections among patients with osteoarticular infections. Antimicrob Resist Infect Control 6:22.


Müller CS, Hubner W, Thieme-Ruffing S, Pföhler C, Vogt T, Volk T, Gärtner BC, Bialas P. Pre- and perioperative aspects of dermatosurgery. J Dtsch Dermatol Ges. 15:117-146.


Becker TK, Bernhard M, Böttiger BW, Rittenberger JC, Epitropoulos MG, Becker SL. Bystander cardiopulmonary resuscitation: a civic duty. Am J Bioeth. 17:51-53.

 

Jung P, Abdelbary MMH, Kraushaar B, Fetsch A, Geisel J, Herrmann M, Witte W, Cuny C, Bischoff M. Impact of bacteriophage Saint3 carriage on the immune evasion capacity and hemolytic potential of Staphylococcus aureus CC398. Vet Microbiol 200:46-51.


Pföhler C, Klotz M, Wehler T, Vogt T, Müller CS. A slowly growing orange patch on the cheek: Diagnosis of Lupus Vulgaris 20 years after onset of first skin changes. Dermatol Ther. 7:181-185.


Deichelbohrer M, Wu MF, Seitz B, Wagenpfeil S, Meier C, Bischoff M, Tschernig T. Gaseous nitric oxide for the local treatment of bacterial keratitis in mice. Biomed Rep. 6:75-78.

 

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2016


Trudzinski FC, Schlotthauer U, Kamp A, Hennemann K, Muellenbach RM, Reischl U, Gärtner B, Wilkens H, Bals R, Herrmann M, Lepper PM, Becker SL. Clinical implications of Mycobacterium chimaera detection in thermoregulatory devices used for extracorporal Membrane oxygenation (ECMO), Germany, 2015 to 2016. Euro Surveill. 21(46). pii: 30398.


Boelaert M, the NIDIAG consortium (...Becker SL,...). Clinical research on neglected Tropical diseases: challenges and solutions. PLoS Negl Trop Dis 10:e0004853.


Becker SL, Yap P, Horié NS, Alirol E, Barbé B, Bhatta NK, Bhattarai NR, Bottieau E, Chatigre JK, Coulibaly JT, Fofana HK, Jacobs J, Karki P, Khanal B, Knopp S, Koirala K, Mahendradhata Y, Mertens P, Meyanti F, Murhandarwati EH, N'Goran EK, Peeling RW, Pradhan B, Ravinetto R, Rijal S, Sacko M, Saye R, Schneeberger PH, Schurmans C, Silué KD, Steinmann P, van Loen H, Verdonck K, van Lieshout L, von Müller L, Yao JA, Boelaert M, Chappuis F, Polman K, Utzinger J. Experiences and lessons from a multicountry NIDIAG study on persistent digestive disorders in the Tropics. PLoS Negl Trop Dis. 10:e0004818.


Wonnenberg B, Jungnickel C, Honecker A, Wolf L, Voss M, Bischoff M, Tschernig T, Herr C, Bals R, Beisswenger C. IL-17A attracts inflammatory cells in murine lung infection with P. aeruginosa. Innate Immun. 22:620-625.


Wolf L, Sapich S, Honecker A, Jungnickel C, Seiler F, Bischoff M, Wonnenberg B, Herr C, Schneider-Daum N, Lehr CM, Bals R, Beisswenger C. IL-17A-mediated expression of epithelial IL-17C promotes inflammation during acute Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 311:L1015-L1022.


Laschke MW, Augustin V, Sahin F, Anschütz D, Metzger W, Scheuer C, Bischoff M, Aktas C, Menger MD. Surface modification by plasma etching impairs early vascularization and tissue incorporation of porous polyethylene (Medpor®) implants. J Biomed Mater Res B. 104:1738-1748.


Borisova M, Gaupp R, Duckworth A, Schneider A, Dalügge D, Mühleck M, Deubel D, Unsleber S, Yu W, Muth G, Bischoff M, Götz F, Mayer C. Peptidoglycan recycling in Gram-positive bacteria is crucial for survival in stationary phase. MBio 7:e00923-16


Ravinetto R, Becker SL, Sacko M, El-Safi S, Mahendradhata Y, Lutumba P, Rijal S, Lim K, Sundar S, N'Goran EK, Verdonck K, Utzinger J, Chappuis F, Boelaert M. Governance and standards in international clinical research: The role of translational consortia. Am J Bioeth. 16:59-61.


Albonico M, Becker SL, Odermatt P, Angheben A, Anselmi M, Amor A, Barda B, Buonfrate D, Cooper P, Gétaz L, Keiser J, Khieu V, Montresor A, Muñoz J, Requena-Méndez A, Savioli L, Speare R, Steinmann P, van Lieshout L, Utzinger J, Bisoffi Z; StrongNet Working Group. StrongNet: An international network to improve diagnostics and access to treatment for

Strongyloidiasis control. PLoS Negl Trop Dis. 10:e0004898.


Coulibaly JT, Ouattara M, Becker SL, Lo NC, Keiser J, N'Goran EK, Ianniello D, Rinaldi L, Cringoli G, Utzinger J. Comparison of sensitivity and faecal egg counts of Mini-FLOTAC using fixed stool samples and Kato-Katz technique for diagnosis of Schistosoma mansoni and soil-transmitted helminths. Acta Trop. 164:107-116.

Kaase M, Schimanski S, Schiller R, Beyreiß B, Thürmer A, Steinmann J, Kempf VA, Hess C, Sobottka I, Fenner I, Ziesing S, Burckhardt I, von Müller L, Hamprecht A, Tammer I, Wantia N, Becker K, Holzmann T, Furitsch M, Volmer G, Gatermann SG. Multicentre investigation of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in German hospitals. Int. J. Med. Microbiol. 306:415-20.

Phaku P, Lebughe M, Strauß L, Peters G, Herrmann M, Mumba D, Mellmann A, Muyembe-Tamfum JJ, Schaumburg F. Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole Genome sequencing. Clin Microbiol Infect. 644.e1-5.


Winkler K, Simon C, Finke M, Bleses K, Birke M, Szentmáry N, Hüttenberger D, Eppig T, Stachon T, Langenbucher A, Foth HJ, Herrmann M, Seitz B, Bischoff M. Photodynamic inactivation of multidrug-resistant Staphylococcus aureus by chlorin e6 and red light (lambda = 670 nm). J Photochem Photobiol B 162:340-7.

Gaupp R, Wirf J, Wonnenberg B, Biegel T, Eisenbeis J, Graham J, Lee CY, Beisswenger C, Wolz V, Tschernig T, Herrmann M, Bischoff M, Somerville GA. RpiRc is a pleiotropic effector of virulence determinant synthesis and attenuates pathogenicity in Staphylococcus aureus. Inf Immun 84:2031-2041.

Mardal M, Miserez B, Bade R, Portolés T, Bischoff M, Hernández F, Meyer MR. 3-Fluorophenmetrazine, a fluorinated analogue of phenmetrazine: Studies on in vivo metabolism in rat and human, in vitro metabolism in human CYP isoenzymes and microbial biotransformation in Pseudomonas putida and wastewater using GC and LC coupled to (HR)-MS techniques. J Pharm Biomed Anal. 128:485-495.

Strauß L, Ruffing U, Abdulla S, Alabi A, Akulenko R, Garrine M, Germann A, Grobusch MP, Helms V, Herrmann M, Kazimoto T, Kern W, Mandomando I, Peters G, Schaumburg F, von Müller L, Mellmann A. Detecting Staphylococcus aureus Virulence and Resistance Genes - a comparison of whole Genome sequencing and DNA microarray technology. J Clin Microbiol 54:1008-16.


Nillius D, von Müller L, Wagenpfeil S, Klein R, Herrmann M. Methicillin-Resistant Staphylococcus aureus in Saarland, Germany: The Long-Term Care Facility Study. PLoS One 11:e0153030.

Preu L, Bischoff M, Veith N, Rosenbruch M, Theegarten D, Laschke MW, Meier C, Tschernig T. Initial host response to bacteria in the murine lung differs between Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae. Inflammation 39:513-7.

Le DD, Funck U, Wronski S, Heck S, Tschernig T, Bischoff M, Sester M, Herr C, Bals R, Welte T, Braun A, Dinh QT. Steroid treatment reduces allergic airway inflammation and does not alter the increased numbers of dendritic cells and calcitonin gene-related peptide-expressing Neurons in airway sensory ganglia. Neuroimmunomodulation 23:18-26.

Schneeberger PHH, Becker SL, Pothier JF, Duffy B, N’Goran EK, Beuret C, Frey JE, Utzinger J. Metagenomic diagnostics for the simultaneous detection of multiple pathogens in human stool specimens from Côte d’Ivoire: a proof-of-concept study. Infect Genet Evol. 40:389-97.

Bischoff M,
Brelle S, Minatelli S, Molle V. Stk1-mediated phosphorylation stimulates the DNA-binding properties of the Staphylococcus aureus SpoVG transcriptional factor. Biochem Biophys Res Commun 473:1223-8.

Saul S, Gibhardt CS, Schmidt B, Lis A, Pasieka B, Conrad D, Jung P, Gaupp R, Wonnenberg B, Diler E, Stanisz H, Vogt T, Schwarz EC, Bischoff M, Herrmann M, Tschernig T, Kappl R, Rieger H, Niemeyer BA, Bogeski I. A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+channels. Sci Signal. 9:ra26.

Elnakady Y, Chatterjee I, Bischoff M, Rohde M, Josten M, Sahl HG, Herrmann M, Müller R. Investigations to the antibacterial mechanism of cction of Kendomycin. PLoS One 11:e0146165.

Brelle S, Baronian G, Huc-Brandt S, Gannoun Zaki L, Cohen-Gonsaud M, Bischoff M, Molle V.Phosphorylation-mediated regulation of the Staphylococcus aureus secreted tyrosine phosphatase PtpA. Biochem Biophys Res Commun 469:619-25.


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2015

Thewes N, Loskill P, Spengler C, Humbert S, Bischoff M, Jacobs K. A detailed guideline for the fabrication of single bacterial probes used for atomic force spectroscopy. Eur Phys J E, 38:140.

von Müller L, Mock M, Halfmann A, Stahlmann J, Simon A, Herrmann M. Epidemiology of Clostridium difficile in Germany based on a single center long-term surveillance and German-wide genotyping of recent isolates provided to the advisory laboratory for diagnostic reasons. Int J Med Microbiol 305:807-13.

Seugendo M, Mshana SE, Hokororo A, Okamo B, Mirambo MM, von Müller L, Gunka K, Zimmermann O, Groß U. Clostridium difficile infections among adults and children in Mwanza/Tanzania: is it an underappreciated pathogen among immunocompromised patients in sub-Saharan Africa? New Microbes New Infect. 8:99-102.

Hamed M, Nitzsche-Schmitz DP, Ruffing U, Steglich M, Dordel J, Nguyen D, Brink JH, ChhatwalGS, Herrmann M, Nübel U, Helms V, von Müller L. Whole Genome Sequence Typing and Microarray Profiling of Nasal and Blood Stream Methicillin-Resistant Staphylococcus aureus Isolates: Clues to Phylogeny and Invasiveness. Infect Genet Evol 36:475-82.

Thewes N, Thewes A, Loskill P, Peisker H, Bischoff M, Herrmann M, Santen L, Jacobs K. Stochastic binding of Staphylococcus aureus to hydrophobic surfaces. Soft Matter 11:8913-9.

Heudorf U, Färber D, Mischler D, Schade M, Zinn C, Cuny C, Nillius D, Herrmann M. Multidrug-Resistant Organisms (MDRO) in Rehabilitation Clinics in the Rhine-Main-District, Germany, 2014: Prevalence and Risk Factors. Rehabilitation 54:339-45.

Shittu AO, Oyedara O, Okon, Raji A, Peters G, von Müller L, Schaumburg, Herrmann M, Ruffing U. An assessment on DNA microarray and sequence-based methods for the characterization of methicillin-susceptible Staphylococcus aureus from Nigeria. Front Microbiol 6:1160.

Steglich M, Nitsche A, von Müller L, Herrmann M, Kohl TA, Niemann S, Nübel U. Tracing the Spread of Clostridium difficile Ribotype 027 in Germany Based on Bacterial Genome Sequences.PLoS One 10:e0139811.

Becker SL, Chatigre JK, Coulibaly JT, Mertens P, Bonfoh B, Herrmann M, Kuijper EJ, N'Goran EK, Utzinger J, von Müller L. Molecular and culture-based diagnosis of Clostridium difficile isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain conditions. Trans R Soc Trop Med Hyg 109:660-8.

Lo NC, Bogoch II, Blackburn BG, Raso G, N’Goran EK, Coulibaly JT, Becker SL, Abrams HB, Utzinger J, Andrews JR. Comparison of community-wide, integrated mass drug Administration strategies for schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling study. Lancet Glob Health 3:e629-38.

Akoua-Koffi C, Honoré T, Plo JK, Monemo P, Cissé A, Yao C, Yenan PJ, Touré FS, Ilupeju V, Bogoch II, Utzinger J, Herrmann M, Becker SL. Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d’Ivoire. New Microbes New Infect 7:100-104.

Polman K, Becker SL, Alirol E, Bhatta NK, Bhattarai NR, Bottieau E, Bratschi MW, Burza S, Coulibaly JT, Doumbia MN, Horié NS, Jacobs J, Khanal B, Landouré A, Mahendradhata Y, Meheus F, Mertens P, Meyanti F, Murhandarwati EH, N’Goran EK, Peeling RW, Ravinetto R, Rijal S, Sacko M, Saye R, Schneeberger PHH, Schurmans C, Silué KD, Thobari JA, Traoré MN, van Lieshout L, van Loen H, Verdonck T, von Müller L, Yansouni CP, Yao JA, Yao PK, Yap P, Boelaert M, Chappuis F, Utzinger J (2015). Diagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain ≥14 days): a multi-country, prospective, non-experimental case-control study. BMC Infect Dis 15:338.

Becker SL, Piraisoody N, Kramme S, Marti H, Silué KD, Panning M, Nickel B, Kern WV, Herrmann M, Hatz CF, N’Goran EK, Utzinger J, von Müller L. Real-time PCR for detection of Strongyloides stercoralis in human stool samples from Côte d’Ivoire: diagnostic accuracy, inter-laboratory comparison and patterns of hookworm co-infection. Acta Tropica 150:210-217.

Becker SL, Marti H, Zimmermann S, Vidacek D, Herrmann M, Utzinger J, Schnabel PA, Bohle RM. Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas. Euro Surveill. 20:pii: 21151.

Utzinger J, Becker SL, van Lieshout L, van Dam GJ, Knopp S. New diagnostic tools in schistosomiasis. Clin Microbiol Infect 21:529-542.

Becker SL, Chappuis F, Polman K, N'Goran EK, von Müller L, Utzinger J. Reply: Epidemiological studies need asymptomatic controls. Clin Microbiol Infect 21:e.53-e.54.

Gaupp R, Lei S, Reed JM, Peisker H, Boyle-Vavra S, Bayer AS, Bischoff M, Herrmann M, Daum RS, Powers R, Somervill GA. Staphylococcus aureus metabolic adaptations during the transition from a daptomycin-susceptible phenotype to a daptomycin-nonsusceptible phenotype. Antimicrob Agents Chemother 59:4226-38.

Song X, Stachon T, Seitz B, Wang J, Bischoff M, Langenbucher A, Janunts E, Szentmáry N. Effekt der photodynamischen Inaktivierung (PDI) mit Riboflavin oder Riboflavin konjugierten Antikörpern gegen Staphylococcus aureus. Klin Monatsbl Augenheilkd 232:988-92.

Hagel S, Epple HJ, Feurle GE, Kern WV, Lynen Jansen P, Malfertheiner P, Marth T, Meyer E, Mielke M, Moos V, von Müller L, Nattermann J, Nothacker M, Pox C, Reisinger E, Salzberger B, Salzer HJ, Weber M, Weinke T, Suerbaum S, Lohse AW, Stallmach A. S2k-guideline gastrointestinal infectious diseases and Whipple's disease. Z Gastroenterol 53:418-459.

Schöndorf D, Hennes P, Rentz K, Becker SL, Schneider G, Rohrer T, Gortner L. Purulent bronchitis caused by Staphylococcus aureus in an adolescent receiving infliximab for Crohn’s disease. Klin Padiatr 227:232-233.

Becker SL, Fürst T, Addiss DG, Utzinger J. Assessing numbers and faces: a prerequisite for improving access to lymphatic filariasis morbidity care. Trans R Soc Trop Med Hyg. 109:357-9.

Becker SL, Chatigre JK, Gohou JP, Coulibaly JT, Leuppi R, Polman K, Chappuis F, Mertens P, Herrmann M, N'Goran EK, Utzinger J, von Müller L. Combined stool-based multiplex PCR and microscopy for enhanced pathogen detection in patients with persistent diarrhoea and asymptomatic controls from Côte d'Ivoire. Clin Microbiol Infect 21:591.e1-591.e10.

Sedlacek L, Graf B, Schwarz C, Albert F, Peter S, Würstl B, Wagner S, Klotz M, Becker A, Haase G, Laniado G, Kahl B, Suerbaum S, Seibold M, Tintelnot K. Prevalence of Scedosporium species and Lomentospora prolificans in patients with cystic fibrosis in a multicenter trial by use of a selective medium. J Cyst Fibros 14:237-41.

Freeman J, Vernon J, Morris K, Nicholson S, Todhunter S, Longshaw C, Wilcox MH;... von Müller L, ... Pan-European Longitudinal Surveillance of Antibiotic Resistance among Prevalent Clostridium difficile Ribotypes' Study Group. Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes. Clin Microbiol Infect 21:248.e9-248.e16.

Tuchscherr L, Bischoff M, Lattar SM, Noto Llana M, Pförtner H, Niemann S, Geraci J, Van de Vyver H, Fraunholz MJ, Cheung AL, Herrmann M, Völker U, Sordelli DO, Peters G, Löffler B. Sigma factor SigB is crucial to mediate Staphylococcus aureus adaptation during chronic infections. PLoS Pathog. 11:e10048

Decker R, Burdelski C, Zobiak M, Büttner H, Franke G, Christner M, Saß K, Zobiak B, Henke HA, Horswill AR, Bischoff M, Bur S, Hartmann T, Schaeffer CR, Fey PD, Rohde H. An 18 kDa scaffold protein is critical for Staphylococcus epidermidis biofilm formation. PLoS Pathog 11:e1004735.

Voss M, Wonnenberg B, Honecker A, Kamyschnikow A, Herr C, Bischoff M, Tschernig T, Bals R, Beisswenger C. Cigarette smoke-promoted acquisition of bacterial pathogens in the upper respiratory tract leads to enhanced inflammation in mice. Resp Research 16:41.

Becker SL, Splettstoesser WD, Kim YJ, Junghanss T, Herrmann M, Wolf G, Linxweiler M. Potential risk of aerosol-borne Francisella tularensis transmission in the operating room. Infect Control Hosp Epidemiol. 36:490-2.

 

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2014

Davies KA, Longshaw CM, Davis GL, Bouza E, Barbut F, Barna Z, Delmée M, Fitzpatrick F, Ivanova K, Kuijper E, Macovei IS, Mentula S, Mastrantonio P, von Müller L, Oleastro M, Petinaki E, Pituch H, Norén T, Nováková E, Nyč O, Rupnik M, Schmid D, Wilcox MH. Underdiagnosis of Clostridium difficile across Europe: the European, multicentre, prospective,

biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID). Lancet Infect Dis. 14:1208-19.

Fruth M, Plaza A, Hinsberger S, Sahner JH, Haupenthal J, Bischoff M, Jansen R, Müller R, Hartmann RW. Binding mode characterization of novel RNA polymerase inhibitors using a combined biochemical and NMR approach. ACS Chem Biol, 9:2656-63.

Stahlmann J, Schönberg M, Herrmann M, von Müller L. Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A/B testing on stool samples. Clin Microbiol Infect. 20:O590-2.

Schaumburg F, Idelevich EA, Peters G, (...), Herrmann M, (...) von Müller L, (...), Wüllenweber J, Würstl B, Zöllner B. Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004–2011). Clin Microbiol Infect. 20:O554-7.

Ballhausen B, Jung P, Kriegeskorte A, Makgotlho PE, Ruffing U, von Müller L, Köck R, Peters G, Herrmann M, Ziebuhr W, Becker K, Bischoff M. LA-MRSA CC398 differ from classical community acquired-MRSA and Hospital acquired-MRSA lineages: functional analysis of infection and colonization processes. Int J Med Microbiol 304:777-86.

Herrmann M, Jungmann S, Halfmann A, Dawson A, Kaase M, Gatermann S, von Müller L, Gärtner BC. A Pseudo-Outbreak due to Acinetobacter Species (GIM-1) Contamination of the Pneumatic Transport System of a Large University Hospital. Infect Control Hosp Epidemiol 35:1364-72.

Nurjadi D, Olalekan AO, Layer F, Shittu AO, Alabi A, Ghebremedhin B, Schaumburg F, Hofmann
-Eifler J, Van Genderen PJ, Caumes E, Fleck R, Mockenhaupt FP, Herrmann M, Kern WV, Abdulla S, Grobusch MP, Kremsner PG, Wolz C, Zanger P. Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe. J Antimicrob Chemother 69:2361-8.

Hartmann T, Baronian G, Nippe N, Voss M, Schulthess B, Wolz C, Eisenbeis J, Schmidt-Hohagen K, Gaupp R, Sunderkötter C, Beisswenger C, Bals R, Somerville GA, Herrmann M, Molle V, Bischoff M. The catabolite control protein E (CcpE) affects virulence determinant production and pathogenesis of Staphylococcus aureus. J Biol Chem 289:29701-11.

Stapels DA, Ramyar KX, Bischoff M, von Köckritz-Blickwede M, Milder FJ, Ruyken M, Eisenbeis J, McWhorter WJ, Herrmann M, van Kessel KP, Geisbrecht BV, Rooijakkers SH. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc Natl Acad Sci USA 111:13187-92.

Gärtner BC, Meyer T. Vaccination in Elite Athletes. Sports Med 44:1361-76.

Thewes N, Loskill PM, Jung P, Peisker H, Bischoff M, Herrmann M, Jacobs K. Hydrophobic interaction governs unspecific adhesion of staphylococci: a single cell force spectroscopy study. Beilstein J Nanotechnol 5:1501–12.

Peisker H, Heepe L, Kovalev AE, Gorb SN. Comperative study of the fluid viscosity in tarsal hairy attachment systems of flies and beetles. J R Soc Interface 11:99.

Becker SL, Millenaar D, Oberkircher N, Herrmann M, Gortner L, Rissland J, Utzinger J, Simon A, von Müller L. Intestinal Cryptosporidiosis in a 6-Year-Old Child with Alpha1-Antitrypsin Deficiency. Klin Padiatr. 226:301-2.

Veith N, Tschernig T, Gutbier B, Witzenrath M, Meier C, Menger MD, Bischoff M. Surfactant protein A mediates pulmonary clearance of Staphylococcus aureus. Resp Research 15:85.

Loskill P, Pereira PM, Jung P, Bischoff M, Herrmann M, Pinho MG, Jacobs K. Reduction of the peptidoglycan crosslinking causes a decrease in stiffness of the Staphylococcus aureus cell envelope. Biophys J, 107:1082-9.

Beisswenger C, Honecker A, Kamyschnikow A, Bischoff M, Tschernig T, Bals R. Moxifloxacin modulates inflammation during murine pneumonia. Resp Research 15:82.

Unger S, Seidl M, Schmitt-Graeff A, Böhm J, Schrenk K, Wehr C, Goldacker S, Dräger R, Gärtner BC, Fisch P, Werner M, Warnatz K. Defined germinal centers and severely reduced Plasma cells are histological hallmarks of lymphadenopathy in patients with common variable immunodeficiency. J Clin Immunol. 34:615-26.

Zimmermann H, Weiland T, Nourse JP, Gandhi MK, Reinke P, Neuhaus R, Karbasiyan M, Gärtner BC, Anagnostopoulos I, Riess H, Trappe RU, Oertel S. Fcγ-receptor IIIA polymorphism p.158F has no negative predictive impact on Rituximab therapy with and without sequential chemotherapy in CD20-positive posttransplant lymphoproliferative disorder. J Immunol Res 2014:264723.

Wonnenberg B, Tschernig T, Voss M, Bischoff M, Meier C, Schirmer SH, Bals R, Beisswenger C. Probenecid reduces infection and inflammation in acute Pseudomonas aeruginosa pneumonia. Int J Med Microbiol., 304:725-9.

Antes S, Tschan CA, Kunze G, Ewert L, Zimmer A, Halfmann A, Oertel J. Clinical and radiological findings in long-term intracranial pressure monitoring. Acta Neurochir. 156:1009-19

Canova MJ, Baronian G, Brelle S, Cohen-Gonsaud M, Bischoff M, Molle V. A novel mode of Regulation of the Staphylococcus aureus Vancomycin-resistance-associated response regulator VraR mediated by Stk1 protein phosphorylation. Biochem Biophys Res Commun. 447:165-71.

Herrmann M. Antimicrobial effects promoting biofilm formation and persistent disease: The role of a DNA-binding regulator, SarA, in staphylococcal endocarditis. J. Infect Dis. 209:1153-5.


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2013

Kresken M, von Müller L, Grabein B, Herrmann M, Höffken G, Hoerauf A, Kern P, Pletz MW, Reisinger E, Cornely OA, Groll AH. Comment of an Expert Group of the Paul-Ehrlich-Society for Chemotherapy on the benefit assessment of fidaxomicin for treatment of Clostridium difficile infections. GMS Infect Dis. 1:Doc07 (20131119)

Dirks J, Tas H, Schmidt T, Kirsch S, Gärtner BC, Sester U, Sester M. PD-1 Analysis on CD28-CD27- CD4 T Cells Allows Stimulation-Independent Assessment of CMV Viremic Episodes in Transplant Recipients. Am J Transplant. 13:3132-41.

Hartmann T, Zhang B, Baronian G, Schulthess B, Homerova D, Grubmüller S, Kutzner E, Gaupp R, Bertram R, Powers R, Eisenreich W, Kormanec J, Herrmann M, Molle V, Somerville GA, Bischoff M. Catabolite control protein E (CcpE) is a LysR-type transcriptional regulator of TCA cycle activity in Staphylococcus aureus. J. Biol. Chem. 288:36116–28.

Stachon T, Wang J, Langenbucher A, Eppig T, Bischoff M, Seitz B, Szentmáry N. IL-1α, IL-1β, IL-6, and IL-8 secretion of human keratocytes following photodynamic inactivation (PDI) in vitro. Graefes Arch Clin Exp Ophthalmol. 251:2585-90.

Li S, Bischoff M, Schirra F, Langenbucher A, Ong M, Halfmann A, Herrmann M, Seitz B. Correlation between microbial growth in conjunctival swabs of corneal donors and contamination of organ culture media. Der Ophthalmologe, [Epub ahead of print].

Kaasch AJ, Rieg S, Kuetscher J, Brodt HR, Widmann T, Herrmann M, Meyer C, Welte T, Kern P, Haars U, Reuter S, Hübner I, Strauss R, Sinha B, Brunkhorst FM, Hellmich M, Fätkenheuer G, Kern WV, Seifert H; The preSABATO study group*. Delay in the administration of appropriate antimicrobial therapy in Staphylococcus aureus bloodstream infection: a prospective multicenter hospital-based cohort study. Infection, 41:979-85.

Herrmann M, Petit C, Dawson A, Biechele J, Halfmann A, von Müller L, Gräber S, Wagenpfeil S, Klein R, Gärtner BC. Methicillin-resistant Staphylococcus aureus in Saarland, Germany: A statewide admission prevalence screening study. PLoS ONE 8:e73876.

Stachon T, Wang J, Eppig T, Langenbucher A, Foth HJ, Bischoff M, Seitz B, Szentmáry N. 1 KGF, FGFb, VEGF, HGF and TGFβ1 secretion of human keratocytes following photodynamic inactivation (PDI) in vitro. Graefes Arch Clin Exp Ophthalmol. 251:1987-93.

Habbal W, Gärtner BC, Monem F. Identification of optimal target gene regions for hepatitis B virus genotyping by DNA sequencing. Intervirology 56:325-36.

Sester U, Schmidt T, Kuhlmann MK, Gärtner BC, Uhlmann-Schiffler H, Sester M. Serial influenza-vaccination reveals impaired maintenance of specific T-cell memory in patients with end-stage renal failure. Vaccine 31:4111-20.

Zakharkina T, Heinzel E, Koczulla RA, Greulich T, Rentz K, Pauling JK, Baumbach J, Herrmann M, Grünewald C, Dienemann H, von Müller L, Bals R. Analysis of the Airway Microbiota of Healthy Individuals and Patients with Chronic Obstructive Pulmonary Disease by T-RFLP and Clone Sequencing. PLoS ONE 8:e68302.

Pappelbaum K, Gorzelanny C, Grässle S, Laschke MW, Bischoff M, Bauer C, Schorpp-Kistner M, Weidenmaier C, Schneppenheim R, Obser T, Bhanu Sinha B, Schneider SW. Ultra-large von Willebrand factor fibers mediate luminal Staphylococcus aureus adhesion to an intact endothelial cell layer under shear stress. Circulation 128:50-59.

Bur S, Preissner KT, Herrmann M, Bischoff M. The Staphylococcus aureus Extracellular Adherence Protein (Eap) Promotes Bacterial Internalisation by Keratinocytes Independent of Fibronectin-binding Proteins. J Invest. Dermatol 133:2004-2012.

Bader O, Weig M, Reichard U, Lugert R, Kuhns M, Christner M, Held J, Peter S, Schumacher U, Buchheidt D, Tintelnot K, Groß U; MykoLabNet-D Partners. cyp51A-Based Mechanisms of Aspergillus fumigatus Azole Drug Resistance Present in Clinical Samples from Germany. Antimicrob Agents Chemother. 57:3513-3517

Ritter M, Schmidt T, Dirks J, Hennes P, Juhasz-Böss I, Solomayer EF, Gortner L, Gärtner BC, Rohrer T, Sester U, Sester M. Cytomegalovirus-specific T cells are detectable in early childhood and allow assignment of the infection status in children with passive maternal antibodies. Eur J Immunol. 43:1099-108.

Tschernig T, Veith NT, Schramm R, Laschke MW, Roller J, Rosenbruch JM,Theegarten D, Bischoff M, Meier C, Menger MD. In vivo observation of micro-particles in peripheral alveoli. Exp. Toxicol. Pathol. 65:883-886.

Loskill P, Zeitz C, Grandthyll S, Thewes N, Müller F, Bischoff M, Herrmann M, Jacobs K. Reduced adhesion of oral bacteria on hydroxyapatite by fluoride treatment. Langmuir 29:5528-5533.

Pfeiffer P, Voss M, Wonnenberg B, Hellberg J, Seiler F, Lepper PM, Bischoff M, Langer F, Schäfers HJ, Menger M, Bals R, Beisswenger C. IL-17C is a mediator of respiratory epithelial innate immune response. Am J Respir Cell Mol Biol 48:415-421.

Seiler F, Hellberg J, Lepper PM, Kamyschnikow A, Herr C, Bischoff M, Langer F, Schäfers HJ, Lammert F, Menger MD, Bals R, Beisswenger C. FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells. J Immunol. 190:1603-1613.

Potapova I, Eglin D, Laschke MW, Bischoff M, Richards RG, Moriarty TF. Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry. J Microbiol Methods 92:90-98.


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2012

Ruffing U, Akulenko R, Bischoff M, Helms V, Herrmann M, von Müller L. Matched-cohort DNA microarray diversity analysis of methicillin sensitive and methicillin resistant Staphylococcus aureus isolates from hospital admission patients. Plos One 7:e52487.

Leiba J, Hartmann T, Cluzel ME, Cohen-Gonsaud, Delolme F, Bischoff M, Molle V. A novel mode of regulation of the Staphylococcus aureus catabolite control protein A (CcpA) mediated by Stk1 phosphorylation. J Biol Chem. 287:43607-19.

Pehlke JR, Geipel U, von Müller L, Spiegel J. Meningoencephalitis and ventricular arrhythmia caused by yersiniosis. Fortschr Neurol Psychiatr. 80:527-9.

von Müller L, Halfmann A, Herrmann M. Current data and trends on the development of antibiotic resistance of Clostridium difficile. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:11-12.

Schaumburg F, Köck R, Mellmann A, Richter L, Hasenberg F, Kriegeskorte A, Friedrich AW, Gatermann S, Peters G, von Eiff C, Becker K; Herrmann M, von Müller L, et al. Population dynamics among methicillin-resistant Staphylococcus aureus isolates in Germany during a 6-year period. J Clin Microbiol. 50:3186-92.

Schmidt T, Dirks J, Enders M, Gärtner BC, Uhlmann-Schiffler H, Sester U, Sester M. CD4+ T- cell immunity after pandemic influenza vaccination cross-reacts with seasonal antigens and functionally differs from active influenza infection. Eur J Immunol. 42:1755-66.

Schmidt T, Ritter M, Dirks J, Gärtner BC, Sester U, Sester M. Cytomegalovirus-specific T-cell immunity to assign the infection status in individuals with passive immunity: a proof of principle. J Clin Virol. 54(3):272-5.

Zimmermann H, Reinke P, Neuhaus R, Lehmkuhl H, Oertel S, Atta J, Planker M, Gärtner BC, Lenze D, Anagnostopoulos I, Riess H, Trappe RU. Burkitt post-transplantation lymphoma in adult solid organ transplant recipients: sequential immunochemotherapy with rituximab (R) followed by cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or R-CHOP is safe and effective in an analysis of 8 patients. Cancer 118:4715-24.

Schmitt J, Joost I, Skaar EP, Herrmann M, Bischoff M. Haemin represses the haemolytic activity of Staphylococcus aureus in a Sae-dependent manner. Microbiology 2012; 158:2619-31.

Weiffenbach J, Bald R, Gloning KP, Minderer S, Gärtner BC, Weidner A, Hanke M, Enders M. Serological and virological analysis of maternal and fetal blood samples in prenatal human parvovirus b19 infection. J Infect Dis. 205(5):782-8.

Zimmermann H, Oschlies I, Fink S, Pott C, Neumayer HH, Lehmkuhl H, Hauser IA, Dreyling M, Kneba M, Gärtner BC, Anagnostopoulos I, Riess H, Klapper W, Trappe RU. Plasmablastic posttransplant lymphoma: cytogenetic aberrations and lack of Epstein-Barr virus association linked with poor outcome in the prospective German Posttransplant Lymphoproliferative Disorder Registry. Transplantation 93:543-50.

Loskill P, Hähl H, Thewes N, Kreis CT, Bischoff M, Herrmann M, Jacobs K. Influence of the subsurface composition of a material on the adhesion of staphylococci. Langmuir 28:7242-7248


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2011

Sadykov MR, Hartmann T, Mattes TA, Hiatt M, Jann NJ, Zhu Y, Ledala N, Landmann R, Herrmann M, Rohde H, Bischoff M, Somerville GA. CcpA coordinates central metabolism and biofilm formation in Staphylococcus epidermidis. Microbiology 157:3458-68.

Balabanova Y, Gilsdorf A, Buda S, Burger R, Eckmanns T, Gärtner BC, Gross U, Haas W, Hamouda O, Hübner J, Jänisch T, Kist M, Kramer MH, Ledig T, Mielke M, Pulz M, Stark K, Suttorp N, Ulbrich U, Wichmann O, Krause G. Communicable diseases prioritized for surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011. PLoS One 6:e25691.

Hermes J, Jansen A, Geipel U, Herrmann M, von Müller L, Haber M, Jung W, Thomé-Granz S, Eckmanns T. Multi-dose packaging of drugs as the causative vehicle for multidrug-resistant Enterobacter cloacae: new results from a case-control study. Gesundheitswesen 73:778-83

Heine S, Fuchs A, von Müller L, Krenn T, Nemat S, Graf N, Simon A. Legionellosis must be kept in mind in case of pneumonia with lung abscesses in children receiving therapeutic steroids. Infection. 39:481-4.

Schulthess B, Bloes DA, François P, Girard M, Schrenzel J, Bischoff M, Berger-Bächi B. The sigmaB-dependent yabJ-spoVG operon is involved in the regulation of extracellular nuclease, lipase and protease expression in Staphylococcus aureus. J Bacteriol. 193:4954-62.

Schaumburg F, Köck R, Friedrich AW, Soulanoudjingar S, Ngoa UA, von Eiff C, Issifou S, Kremsner PG, Herrmann M, Peters G, Becker K. Population structure of Staphylococcus aureus from remote African Babongo Pygmies. PLoS Negl Trop Dis. 5:e1150.

Sethi S, Herrmann M, Roller J, von Müller L, Peerschke EI, Ghebrehiwet B, Bajric I, Menger MD, Laschke MW. Blockade of gC1qR/p33, a receptor for C1q, inhibits adherence of Staphylococcus aureus to the microvascular endothelium. Microvasc Res. 82:66-72.

Rupf S, Idlibi AN, Marrawi FA, Hannig M, Schubert A, von Müller L, Spitzer W, Holtmann H, Lehmann A, Rueppell A, Schindler A. Removing biofilms from microstructured titanium ex vivo: a novel approach using atmospheric plasma technology. PLoS One 6:e25893.

Pföhler C, Koerner R, von Müller L, Vogt T, Müller CS. Lues maligna in a patient with unknown HIV infection. BMJ Case Rep. doi:pii: bcr0520114221.

Halfmann A, Schnorpfeil A, Müller M, Marx P, Günzler U, Hakenbeck R, Brückner R. Activity of the two-component regulatory system CiaRH in Streptococcus pneumoniae R6. J Mol Microbiol Biotechnol. 20:96-104.

Chatterjee I,
Maisonneuve E, Ezraty B, Herrmann M, Dukan S. Staphylococcus aureus ClpC is involved in protection of carbon-metabolizing enzymes from carbonylation during stationary growth phase. Int J Med Microbiol. 301:341-6.

Joost I, Jacob S, Utermöhlen O, Schubert U, Patti JM, Ong MF, Gross J, Justinger C, Renno JH, Preissner KT, Bischoff M, Herrmann M. Antibody response to the extracellular adherence protein (Eap) of Staphylococcus aureus in healthy and infected individuals. FEMS Immunol Med Microbiol. 62:23-31.

Sever-Chroneos Z, Krupa A, Davis J, Hasan M, Yang CH, Szeliga J, Herrmann M, Hussain M, Geisbrecht BV, Kobzik L, Chroneos ZC. Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A. J Biol Chem. 286:4854-70.

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Universität des Saarlandes
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Fax: (+49) 6841 16-23985
E-Mail: mikrobiologie@uks.eu

 

 

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