Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Klinik für Neurochirurgie
Leitung: Prof. Dr. Joachim Oertel
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Eigene Publikationen

Ketter R, Rahnenführer J, Henn W, Kim YJ, Feiden W, Steudel WI, Zang KD, Urbschat S.Correspondence of tumor localization with tumor recurrence and cytogenetic progression in meningiomas. Neurosurgery. 2008 Jan;62(1):61-9; discussion 69-70.


Strowitzki M, Brand S, Ketter R, Steudel WI, Jenderka KV. Ultrasonic radio-frequency spectrum analysis differentiates normal and edematous brain tissue from meningioma intraoperatively. J Neuroimaging. 2008 Jan;18(1):73-80.


Hellwig D, Romeike BF, Ketter R, Moringlane JR, Kirsch CM, Samnick S. Intra-individual comparison of p-[(123)I]-iodo-L-phenylalanine and L-3-[ (123)I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas. Eur J Nucl Med Mol Imaging. 2008 Jan;35(1):24-31. Epub 2007 Sep 11.


Kim YJ, Ketter R, Steudel WI, Feiden W. Prognostic significance of the mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomas. Am J Clin Pathol. 2007 Jul;128(1):118-25.


Ketter R, Urbschat S, Henn W, Feiden W, Beerenwinkel N, Lengauer T, Steudel WI, Zang KD, Rahnenführer J. Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas. Int J Cancer. 2007 Oct 1;121(7):1473-80.


Bauer C, Kreuer S, Ketter R, Grundmann U, Wilhelm W. Remifentanil-propofol versus fentanyl-midazolam combinations for intracranial surgery: influence of anaesthesia technique and intensive sedation on ventilation times and duration of stay in the ICU Anaesthesist. 2007 Feb;56(2):128-32. German.

Ketter R, Kim YJ, Storck S, Rahnenführer J, Romeike BF, Steudel WI, Zang KD, Henn W. Hyperdiploidy defines a distinct cytogenetic entity of meningiomas. J Neurooncol. 2007 Jun;83(2):213-21. Epub 2007 Jan 17.

Kim YJ, Ketter R, Henn W, Zang KD, Steudel WI, Feiden W. Histopathologic indicators of recurrence in meningiomas: correlation with clinical and genetic parameters.Virchows Arch. 2006 Nov;449(5):529-38. Epub 2006 Oct 3. PMID: 17016718 [PubMed - in process]

Wemmert S, Romeike BF, Ketter R, Steudel WI, Zang KD, Urbschat S. Intratumoral genetic heterogeneity in pilocytic astrocytomas revealed by CGH-analysis of microdissected tumor cells and FISH on tumor tissue sections.Int J Oncol.2006 Feb;28(2):353-60. PMID: 16391789 [PubMed - in process]

Wemmert S, Ketter R, Rahnenfuhrer J, Beerenwinkel N, Strowitzki M, Feiden W, Hartmann C, Lengauer T, Stockhammer F, Zang KD, Meese E, Steudel WI, von Deimling A, Urbschat S. Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment. Neoplasia. 2005 Oct;7(10):883-93. PMID: 16242071 [PubMed - indexed for MEDLINE]

Hellwig D, Ketter R, Romeike BF, Sell N, Schaefer A, Moringlane JR, Kirsch CM, Samnick S. Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT. Eur J Nucl Med Mol Imaging. 2005 Sep;32(9):1041-9. Epub 2005 May 18. PMID: 15902439 [PubMed - indexed for MEDLINE]

Prowald A, Wemmert S, Biehl C, Storck S, Martin T, Henn W, Ketter R, Meese E, Zang KD, Steudel WI, Urbschat S. Interstitial loss and gain of sequences on chromosome 22 in meningiomas with normal karyotype. Int J Oncol.2005 Feb;26(2):385-93. PMID: 15645123 [PubMed - indexed for MEDLINE]

Wullich B, Riedinger S, Brinck U, Stoeckle M, Kamradt J, Ketter R, Jung V. Evidence for gains at 15q and 20q in brain metastases of prostate cancer. Cancer Genet Cytogenet. 2004 Oct 15;154(2):119-23. PMID: 15474146 [PubMed - indexed for MEDLINE]

Ketter R, Henn W, Feiden W, Prowald A, Sittel C, Steudel WI, Strowitzki M. Nasoethmoidal meningioma with cytogenetic features of tumor aggressiveness in a 16-year-old child. Pediatr Neurosurg. 2003 Oct;39(4):190-4. PMID: 12944699 [PubMed - indexed for MEDLINE]

Henn W, Niedermayer I, Ketter R, Reichardt S, Freiler A, Zang KD.Monosomy 7p in meningiomas: a rare constituent of tumor progression. Cancer Genet Cytogenet. 2003 Jul 1;144(1):65-8. PMID: 12810258 [PubMed - indexed for MEDLINE]

Schmits R, Cochlovius B, Treitz G, Regitz E, Ketter R, Preuss KD, Romeike BF, Pfreundschuh M. Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas. Int J Cancer. 2002 Mar 1;98(1):73-7. PMID: 11857388 [PubMed - indexed for MEDLINE]

Wullich B, Rohde V, Oehlenschlager B, Bonkhoff H, Ketter R, Zwergel T, Sattler HP.Focal intratumoral heterogeneity for telomerase activity in human prostate cancer. J Urol. 1999 Jun;161(6):1997-2001. PMID: 10332489 [PubMed - indexed for MEDLINE]

Nieder C, Nestle U, Ketter R, Kolles H, Gentner SJ, Steudel WI, Schnabel K. Hyperfractionated and accelerated-hyperfractionated radiotherapy for glioblastoma multiforme.Radiat Oncol Investig.1999;7(1):36-41. PMID: 10030622 [PubMed - indexed for MEDLINE]

Ketter R, Zwergel T, Romanakis K, Unteregger G, Ziegler M, Zang KD, Wullich B. Selection toward diploid cells in prostatic carcinoma derived cell cultures.Prostate. 1996 Jun;28(6):364-71. PMID: 8650073 [PubMed - indexed for MEDLINE]

Ketter R,
von Ballestrem CL, Lampel S, Seitz G, Zang KD, Romanakis K, Wullich B. Rearrangement of chromosome 1 is a frequent finding in endometrial carcinoma. An in situ hybridization study in nine endometrial carcinomas. Cancer Genet Cytogenet. 1995 Jun;81(2):109-14. PMID: 7621405 [PubMed - indexed for MEDLINE]

Steilen H, Ketter R, Romanakis K, Zwergel T, Unteregger G, Bonkhoff H, Seitz G, Ziegler M, Zang KD, Wullich B. DNA aneuploidy in prostatic adenocarcinoma: a frequent event as shown by fluorescence in situ DNA hybridization. Hum Pathol. 1994 Dec;25(12):1306-13. PMID: 8001925 [PubMed - indexed for MEDLINE]

Henn W, Cremerius U, Heide G, Lippitz B, Schröder JM, Gilsbach JM, Büll U, Zang KD: Monosomy 1p is correlated with enhanced in vivo glucose metabolism in meningiomas. Cancer Genet Cytogenet 79: 144-148, 1995

Ketter R, Henn W, Niedermayer I, Steilen-Gimbel H, König J, Zang KD, Steudel WI: Predictive value of progression-associated chromosomal aberrations for the prognosis of meningiomas: a retrospective study of 198 cases. J Neurosurg 95(4): 601-7, 2001

Kolles H, Niedermayer I, Schmitt Ch, Henn W, Feld R, Steudel WI, Zang KD, Feiden W: Triple approach for diagnosis and grading of meningiomas: histology, morphometry of Ki-67/Feulgen stainings, and cytogenetics. Acta Neurochir (Vienna) 137: 174-181, 1995

Mueller P, Henn W, Niedermayer I, Ketter R, Feiden W, Steudel WI, Zang KD, Steilen-Gimbel H: Deletion of chromosome 1p and loss of expression of alkaline phosphatase indicate progression of meningiomas. Clin Cancer Res 5: 3569-3577, 1999

Niedermayer I, Kolles H, Zang KD, Feiden W: Characterization of intermediate type (WHO "atypical") meningiomas.

Niedermayer I, Kolles H, Henn W, Zang KD, Steudel WI, Feiden W. Meningioma. Classification and grading Pathologe.

Niedermayer I, Feiden W, Henn W, Steilen-Gimbel H, Steudel WI, Zang KD: Loss of alkaline phosphatase activity in meningiomas: a rapid histochemical technique indicating progression-assoziated deletion of a putative tumor suppressor gene on the distal part of the short arm of chromosome 1. J Neuropathol Exp Neurol 56: 879-886, 1997a

Prowald A, Vater K, Ketter R, Freiler A, Henn W, Zang KD, Steudel W-I: Down-regulation of the expression of tissue-unspecific alkaline phosphatase enzyme (EC during the progression of meningioma, Berichte aus der Medizin, 2002a

Prowald A, Vater K, Ketter R, Henn W, Zang KD, Steudel W-I: Analysis of the human liver/bone/kidney type alkaline phosphatase gene in meningiomas, J Cancer Res Clin Oncol 128 (supplement 1): 99, 2002b

Steilen-Gimbel H, Niedermayer I, Feiden W, Freiler A, Steudel WI, Zang KD, Henn W: Unbalanced translocation t(1;3)(p12-13;q11) in meningiomas as the unique feature of chordoid differentiation. Genes Chromosomes Cancer: 26(3):270-2, 1999

Steudel WI, Feld R, Henn W, Zang KD: Correlation between cytogenetic and clinical findings in 215 human meningiomas. Acta Neurochir [Suppl] 65: 73-76, 1996

Weber GA, Sass C, Ketter R, Henn W, Steudel W-I, Zang KD: Mikrodissektion an Alkalische Phosphatase gefärbten Meningeomschnitten zur CGH Analyse. Berichte aus der Medizin, 2002

Zang KD: Cytological and cytogenetical studies on human meningioma. Cancer Genet Cytogenet 6: 249-274, 1982

Zang KD, Singer H: Chromosomal constitution of meningiomas. Nature 216: 84-85, 1967

Zang KD: Meningioma: a cytogenetic model of a complex benign human tumor, including data on 394 karyotyped cases. Cytogenet Cell Genet 93(3-4): 207-20, 2001

Zankl H, Zang KD: Correlation between clinical and cytogenetical data in 180 human meningiomas. Cancer Genet Cytogenet 1: 351-356, 1980
Clin Neuropathol 15: 330-336, 1996 18(5): 353-8, 1997b