Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
Klinik für Innere Medizin II - Gastroenterologie und Endokrinologie
Kommissarischer Leiter der Klinik: Prof. Dr. med. Marcin Krawczyk
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Bauer C, Dauer M, Saraj S, Schnurr M, Bauernfeind F, Sterzik A, Junkmann J, Jakl V, Kiefl R, Oduncu F, Emmerich B, Mayr D, Mussack T, Bruns C, Rüttinger D, Conrad C, Jauch KW, Endres S, Eigler A
Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study
Cancer Immunol Immunother. 2011 May 6


Biecker E, Hausdörfer I, Grünhage F, Strunk H, Sauerbruch T
Critical flicker frequency as a marker of hepatic encephalopathy in patients before and after transjugular intrahepatic portosystemic shunt
Digestion. 2011;83(1-2):24-31


Boyer TD, Sanyal AJ, Garcia-Tsao G, Regenstein F, Rossaro L, Appenrodt B, Gülberg V, Sigal S, Bexon AS, Teuber P; Terlipressin Study Group.
Impact of liver transplantation on the survival of patients treated for hepatorenal syndrome type 1.
Liver Transpl. 2011 Nov;17(11):1328-32. doi: 10.1002/lt.22395.


Casper M, Grünhage F, Lammert F
Cancer risk in chronic hepatitis B: Do genome-wide association studies hit the mark?
Hepatology. 2011 Apr;53(4):1390-2


Casper M, Lammert F.
[Gallstone disease: basic mechanisms, diagnosis and therapy].
Praxis (Bern 1994). 2011 Nov 16;100(23):1403-12. Review. German.


Duewell P, Kisser U, Heckelsmiller K, Hoves S, Stoitzner P, Koernig S, Morelli AB, Clausen BE, Dauer M, Eigler A, Anz D, Bourquin C, Maraskovsky E, Endres S, Schnurr M
ISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cells In Vivo Leading to Effective Cross-Priming of CD8+ T Cells
J Immunol. 2011 Jul 1;187(1):55-63


Firrincieli D, Zuniga S, Poupon R, Housset C, Chignard N
Role of nuclear receptors in the biliary epithelium
Dig Dis. 2011;29(1):52-7


Heikkilä T, Karjalainen M, Ojala K, Partola K, Lammert F, Augustijns P, Urtti A, Yliperttula M, Peltonen L, Hirvonen J
Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid
Int J Pharm. 2011 Feb 28;405(1-2):132-6


Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, Kisser U, Bauer CA, Dauer M, Eigler A, Maraskovsky E, Endres S, Schnurr M
An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma
Int J Cancer. 2011 Feb 15;128(4):897-907


Jaursch-Hancke C, Schumm-Dräger P, Lammert F, Müller-Marbach AM
Professional prospects for specialists in internal medicine in the hospital
Dtsch Med Wochenschr. 2011 Feb;136(5):225-6


Jüngst C, Lammert F
Differenzialdiagnose der Cholestase
Gastroenterologie up2date, 2011 7(2): 87-101


Jurkowski W, Roomp K, Crespo I, Schneider JG, Del Sol A.
PPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome.
Cell Death Dis. 2011 Aug 11;2:e192. doi: 10.1038/cddis.2011.74.


Krawczyk M, Gruenhage F, Mahler M, Tirziu S, Acalovschi M, Lammert F
The common adiponutrin variant p.I148M does not confer gallstone risk but affects fasting glucose and triglyceride levels
J Physiol Pharmacol. 2011 Jun;62(3):369-75


Krawczyk M, Grünhage F, Zimmer V, Lammert F
Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease
J Hepatol. 2011 Aug;55(2):299-306


Krawczyk M, Mihalache F, Höblinger A, Acalovschi M, Lammert F, Zimmer V.
Pancreatic cancer risk variant ABO rs505922 in patients with cholangiocarcinoma.
World J Gastroenterol. 2011 Nov 7;17(41):4640-2.


Krawczyk M, Wang DQ, Portincasa P, Lammert F
Dissecting the genetic heterogeneity of gallbladder stone formation
Semin Liver Dis. 2011 May;31(2):157-72


Liu Y, Meyer C, Müller A, Herweck F, Li Q, Muellenbach R, Mertens PR, Dooley S, Weng HL
IL-13 induces connective tissue growth factor in rat hepatic stellate cells via TGF-beta independent Smad signaling
J Immunol. 2011 Sep 1;187(5):2814-23


Lutz P, Wasmuth JC, Nischalke HD, Vidovic N, Grünhage F, Lammert F, Oldenburg J, Rockstroh JK, Sauerbruch T, Spengler U
Progression of liver fibrosis in HIV/HCV genotype 1 co-infected patients is related to the T allele of the rs12979860 polymorphism of the IL28B gene
Eur J Med Res. 2011 Aug 8;16(8):335-41


Menges M
Gastric cancer : Where is the place for the surgeon, the oncologist and the endoscopist today?
World J Gastrointestinal Oncol 2011; 3(1):10-13


Mihalache F, Höblinger A, Grünhage F, Krawczyk M, Gärtner BC, Acalovschi M, Sauerbruch T, Lammert F, Zimmer V
Heterozygosity for the alpha1-antitrypsin Z allele may confer genetic risk of cholangiocarcinoma
Aliment Pharmacol Ther. 2011 Feb;33(3):389-94


Müllenbach R, Lammert F
An update on genetic analysis of cholestatic liver diseases: digging deeper
Dig Dis. 2011;29(1):72-7


Nischalke HD, Berger C, Aldenhoff K, Thyssen L, Gentemann M, Grünhage F, Lammert F, Nattermann J, Sauerbruch T, Spengler U, Appenrodt B
Toll-like receptor (TLR) 2 promotor and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis
J Hepatol. 2011 Feb 25


Nischalke HD, Berger C, Luda C, Berg T, Müller T, Grünhage F, Lammert F, Coenen M, Krämer B, Körner C, Vidovic N, Oldenburg J, Nattermann J, Sauerbruch T, Spengler U.
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.
PLoS One. 2011;6(11):e27087


Nischalke HD, Lammert F, Spengler U, Appenrodt B
The potential role of specific TLR2 gene polymorphisms as host risk factors for spontaneous bacterial peritonitis.
J Hepatol. 2011 Oct 19


Pieper-Fürst U, Hall R, Huss S, Hochrath K, Fischer HP, Tacke F, Weiskirchen R, Lammert F
Expression of the megalin C-terminal fragment by macrophages during liver fibrogenesis in mice
Biochim Biophys Acta. 2011 Sep 10


Rusticeanu M, Schuster M, Moga SL, Solomayer EF, Bohle RM, Lammert F, Zimmer V
Metastatic lobular breast cancer presenting as gastric linitis plastica
Am J Med. 2011 Jul;124(7):e5-6


Schneider JG, Amend SR, Weilbaecher KN.
Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.
Bone. 2011 Jan;48(1):54-65


Schuster M, Lüttges J, Lammert F, Grünhage F
50-jähriger Patienten mit intermittierendem Fieber und Leberversagen
Dtsch Med Wochenschr. 2011 Jan;136(3):87-8


Schuster M, Lüttges J, Lammert F, Grünhage F.
[50-year-old patient with intermittent fever and liver failure].
Dtsch Med Wochenschr. 2011 Jan;136(3):87-8


Sivritas D, Becher MU, Ebrahimian T, Arfa O, Rapp S, Bohner A, Mueller CF, Umemura T, Wassmann S, Nickenig G, Wassmann K
Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase
Basic Res Cardiol. 2011 Jun;106(4):563-75


Slotta JE, Heine S, Kauffels A, Krenn T, Grünhage F, Wagner M, Graf N, Schilling MK, Schuld J
Gastrectomy with isoperistaltic jejunal parallel pouch in a 15-year-old adolescent boy with gastric adenocarcinoma and autosomal recessive agammaglobulinemia
J Pediatr Surg. 2011 Sep;46(9):e21-4


Slotta JE, Jüngling B, Kim YJ, Wagner M, Igna D, Schilling MK
Hepatoid adenocarcinoma of the transverse colon
Int J Colorectal Dis. 2011 Aug 16


Stickel F, Buch S, Lau K, zu Schwabedissen HM, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch M, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Kiefer F, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
Hepatology. 2011 Jan;53(1):86-95


Stokes CS, M Krawczyk, F Lammert
Gallstones: environment, lifestyle and genes
Dig Dis. 2011;29(2):191-201


Tönjes A, Wittenburg H, Halbritter J, Renner O, Harsch S, Stange EF, Lammert F, Stumvoll M, Kovacs P.
Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts.
BMC Med Genet. 2011 Nov 17;12:149.


Trebicka J, Krag A, Gansweid S, Appenrodt B, Schiedermaier P, Sauerbruch T, Spengler U.
Endotoxin and tumor necrosis factor-receptor levels in portal and hepatic vein of patients with alcoholic liver cirrhosis receiving elective transjugular intrahepatic portosystemic shunt.
Eur J Gastroenterol Hepatol. 2011 Nov;23(12):1218-25.


Weber SN, Lammert F
Genetics of liver injury and fibrosis
Alcohol Clin Exp Res. 2011 May;35(5):800-3


Wei X, Schneider JG, Shenouda SM, Lee A, Towler DA, Chakravarthy MV, Vita JA, Semenkovich CF.
De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.
J Biol Chem. 2011 Jan 28;286(4):2933-45. Epub 2010 Nov 23.


Wex T, Kuester D, Schönberg C, Schindele D, Treiber G, Malfertheiner P
Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression
BMC Gastroenterol. 2011 May 26;11:63


Wree A, Canbay A, Müller-Beissenhirtz H, Dechêne A, Gerken G, Dührsen U, Lammert F, Nückel H
Excessive bilirubin elevation in a patient with hereditary spherocytosis and intrahepatic cholestasis
Z Gastroenterol. 2011 Aug;49(8):977-80


Zimmer V, Dauer M, Lammert F
One less ulcer, one extra pylorus
Dig Liver Dis. 2011 Jul;43(7):e13


Zimmer V, Grobholz R, Lammert F, Raedle J.
Endoscopic resection of a large duodenal hamartoma related to SMAD4-associated juvenile polyposis/hereditary hemorrhagic teleangiectasia syndrome.
Am J Gastroenterol. 2011 Nov;106(11):2047-8. doi: 10.1038/ajg.2011.240


Zimmer V, Grünhage F, Jüngling B, Kraemer J, Bohle RM, Lammert F
A stomach carpeted red
Dig Liver Dis. 2011 Apr;43(4):334-5


Zimmer V, Kraemer J, Buecker A, Schilling MK, Lammert F, Menges M
Invasion of a fundoplication sleeve by esophageal squamous cell carcinoma
Gastrointest Cancer Res. 2011 May;4(3):109-10


Zimmer V, Lammert F
Das „Who is who“ des Ösophagus
Gastroenterologe 2011; 6: 159-160


Zimmer V, Lammert F
Fortschritt in der palliativen Therapie des Gallenwegskarzinoms
Gastroenterologe 2011; 6: 49-50


Zimmer V, Lammert F
Genetics and epigenetics in the fibrogenic evolution of chronic liver diseases
Best Pract Res Clin Gastroenterol. 2011 Apr;25(2):269-80


Zimmer V, Lammert F
Genetics in liver disease: new concepts
Curr Opin Gastroenterol. 2011 May;27(3):231-9


Zimmer V, Raedle J, Grobholz R, Massmann A, Schilling MK, Lammert F
Multiple complicated gallbladder disease
J Gastrointestin Liver Dis. 2011 Mar;20(1):98-9


Zimmer V, Raedle J, Treiber G, Lammert F
Biliary cast syndrome in sclerosing cholangitis
Dig Liver Dis. 2011 Feb;43(2):e4


Zúñiga S, Firrincieli D, Housset C, Chignard N
Vitamin D and the vitamin D receptor in liver pathophysiology
Clin Res Hepatol Gastroenterol. 2011 Apr;35(4):295-302