Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
2008
Direktor der Klinik: Prof. Dr. med. Jörn Schattenberg

2008

Originalarbeiten

  1. Dauer M, Lam V, Arnold H, Junkmann J, Kiefl R, Bauer C, Schnurr M, Endres S, Eigler A
    Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-deriveddendritic cells capable of migration and IL-12p70 production
    J Immunol Methods. 2008 Sep 15;337(2):97-105
  2. DeSantis P, Coleman T, Schiekofer S, Nawroth PP, Schlimmer P, Schneider JG
    Endothelial Lipase: a key player in HDL metabolism modulates inflammation and atherosclerotic risk
    Mini Rev Med Chem. 2008 Jun;8(6):619-27
  3. Friedrich-Rust M., Ong M.F., Martens S., Sarrazin C., Bojunga J., Zeuzem S., Herrmann E
    Performance of transient elastography for the staging of liver fibrosis: A metaanalysis
    Gastroenterology 2008;134(4):960-974
  4. Friedrich-Rust M, Herrmann E, Zeuzem S, Sarrazin C
    Reply to Real-time elastography in the assessment of liver fibrosis
    AJR Am J Roentgenol. 2008 Feb;190(2):W164
  5. Friedrich-Rust M, Koch C, Rentzsch A, Sarrazin C, Schwarz P, Herrmann E, Lindinger A, Sarrazin U, Poynard T, Schäfers HJ, Zeuzem S, Abdul-Khaliq H
    Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers
    J Thorac Cardiovasc Surg. 2008 Mar;135(3):560-7
  6. Glantz A, Reilly SJ, Benthin L, Lammert F, Mattson LA, Marschall HU
    Intrahepatic cholestasis of pregnancy: amelioration of pruritus by UDCA is associated with decreased progesterone disulphates in urine
    Hepatology 2008;47(1):544-551
  7. Gottschling S, Reinhard H, Pagenstecher C, Kruger S, Rädle J, Plotz G, Henn W., Büttner R, Meyer S, Graf N
    Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects
    Eur J Pediatr 2008;167(2):225-229
  8. Grünhage F, Jungck M, Lamberti C, Berg C, Becker ., Schulte-Witte H, Plassmann D, Rahner N, Aretz S, Friedrichs N, Büttner R, Sauerbruch T, Lammert F
    Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes
    Int J Colorectal Dis 2008;23(2):147-154
  9. Grünhage F, Jungck M, Lamberti C, Schulte-Witte H, Plassmann D, Becker U, Rahner N, Aretz S, Friedrichs N, Büttner R, Sauerbuch T, Lammert F
    Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer
    Cancer Biomark 2008;4(2):55-61
  10. Grünhage F, Rezori B, Neef M, Lammert F, Sauerbruch T, Spengler U, Reichel C
    Elevated soluble tumor necrosis factor receptor 75 serum concentrations identify patients with liver cirrhosis who are at risk of death
    Clin Gastroenterol Hepatol 2008 Nov;6(11):1255-62
  11. Grünhage F, Heller J, Appenrodt B, Schmitz V, Sauerbruch T
    Medikamentöse Therapie der Komplikationen der Leberzirrhose
    Medizinische Klinik 2008;103:482-90 (Nr. 7): 482-490
  12. Grünhage F, Jungck M, Lamberti C, Keppeler H, Becker U, Schulte-Witte H, Plassmann D, Friedrichs N, Büttner R, Aretz S, Sauerbruch T, Lammert F
    Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: a case control study
    BMC Med Genet 2008; 9 (1): 70 (1-7)
  13. Hellwig D, Gouverneur E, Schaefer A, Raedle J, Menges M, Kirsch CM, Samnick S
    Para-[(123)I]iodo-L-phenylalanine in patients with pancreatic adenocarcinoma: tumour uptake, whole-body kinetics, dosimetry
    Nuklearmedizin. 2008;47(5):220-4
  14. Höblinger A, Tiemann K, Nickenig G, Sauerbruch T, Lammert F
    Resolution of refractory ascites after transcoronary septal ablation of hypertrophic obstructive cariomyopathy in a cirrhotic patient
    Z Gastroenterol 2008 Oct;46(10):1194-7. Epub 2008 Oct 20.
  15. Hofmann WP, Rädle J, Moench C, Bechstein W, Zeuzem S
    Prädiktion der perioperativen Mortalität bei Patienten mit fortgeschrittener Lebererkrankung und abdominalchirurgischen Eingriffen anhand unterschiedlicher Score- und Testsysteme
    Z Gastroenterol 2008; 46: 1283-1289
  16. Kovacs P, Kress R, Rocha J, Kurtz U, Miquel JF, Nervi F, Méndez-Sánchez N, Uribe M, Bock HH, Schirin-Sokhan R, Stumvoll M, Mössner J, Lammert F, Wittenburg H
    Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans
    J Hepatol 2008;48:116-124
  17. Krawczyk M, Wolska M, Schwartz S, Grünhage F, Terjung B, Portincasa P, Sauerbruch T, Lammert F
    Concordance of genetic and breath tests for lactose intolerance in a tertiary referral centre
    J Gastrointestin Liver Dis 2008 Jun;17(2):135-9
  18. Lammert F, Sauerbruch T
    Kurzfassung der aktualisierten S3-Leitlinie der DGVS und DGAV zur Diagnostik und Behandlung von Gallensteinen
    Dtsch Med Wochenschr 2008;133(7):311-316
  19. Martin G, Wex T, Treiber G, Malfertheiner P, Nardone G
    Low-dose aspirin reduces the gene expression of gastrokine-1 in the antral mucosa of healthy subjects
    Aliment Pharmacol Ther. 2008 Sep 15;28(6):782-8
  20. Mühlenberg K, Wiedmann K, Keppeler H, Sauerbruch T, Lammert F
    Rezidivierende Schwangerschaftscholestase und perlschnurartige Choledocholithiasis bei einer Patientin mit Stoppcodon im nABCB4-Gen des hepatischen Phospholipid-Transporters
    Z Gastroenterol 2008;46(1):48-53
  21. Plotz G, Rädle J, Spina A, Welsch C, Stallmach A, Zeuzem S, Schmidt C
    Evaluation of the MLH1 I219V alteration in DNA mismatch repair activity and ulcerative colitis
    Inflamm Bowel Dis 2008;14(5):605-611
  22. Pugnale P, Herrmann E, Neumann AU, Pawlotsky JM, Schalm SW, Ferrari C, Homburger Y, Zeuzem S, Negro F, for the DITTO-HCV Study Group
    Hepatitis C viral kinetics in plasma and peripheral blood mononuclear cells during pegylated interferon-alpha2a/ribavirin therapy
    J Hepatol 2008;48(6):932-938
  23. Raedle-Hurst TM, Welsch C, Forestier N, Kronenberger B, Hess G, Herrmann E, Zeuzem S, Raedle J
    Validity of N-terminal propeptide of the brain natriuretic peptide in predicting left ventricular diastolic dysfunction diagnosed by tissue Doppler imaging in patients with chronic liver disease
    Eur J Gastroenterol Hepatol. 2008 Sep;20(9):865-73
  24. Schiekofer S, Belisle K, Galasso G, Schneider JG, Boehm BO, Burster T, Schmitz G, Walsh K
    Angiogenic-regulatory network revealed by molecular profiling heart tissue following Akt1 induction in endothelial cells
    Angiogenesis. 2008;11(3):289-99
  25. Shin A, Toy T, Rothenfusser S, Robson N, Vorac J, Dauer M, Stuplich M, Endres S, Cebon J, Maraskovsky E, Schnurr M
    P2Y receptor signaling regulates phenotype and IFN-alpha secretion of human plasmacytoid dendritic cells
    Blood. 2008 Mar 15;111(6):3062-9
  26. Stylinski R, Krawczyk M, Majewski M, Pedowski T, Wallner G
    Lapaoscopic surgery in large bowel cancer
    Onko Info 2008;5(3):93-97
  27. Tang KH, Herrmann E, Pachiadakis I, Paulon E, Tatman N, Zeuzem S, Naoumov NV
    Clinical trial: Individualized treatment duration for hepatitis C virus genotype 1 with peginterferon-alpha 2a plus ribavirin
    Aliment Pharmacol Ther 2008;27(9):810-819
  28. Trebicka J, Biecker E, Grünhage F, Stolte M, Meier-Ruge WA, Sauerbruch T, Lammert F
    Diagnosis of megacystis-microcolon intestinal hypoperistalsis syndrome with aplastic desmosis in adulthood: a case report
    Eur J Gastroenterol Hepatol 2008;20(4):353-355
  29. Trebicka J, Leifeld L, Hennenberg M, Biecker E, Eckhardt A, Fischer N, Schulze Pröbsting A., Clemens C., Lammert F, Sauerbruch T, Heller J
    Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats
    Hepatology 2008;47(4):1264-1276
  30. Trudzinski FC, Rädle J, Treiber, G, Kramm T, Sybrecht, GW
    Ausgedehnter Pleuraerguss bei chronischer Pankreatitis Behandlung durch endoskopischen Verschluss einer pankreatikomediastinalen Fistel
    Dtsch med Wochenschr 2008; 133: 2507-2509
  31. Venerito M, Kuester D, Wex T, Roessner A, Malfertheiner P, Treiber G
    The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis
    Cancer Lett. 2008 Nov 8;270(2):218-28. Epub 2008 Jun 20.
  32. Venerito M, Treiber G, Wex T, Kuester D, Roessner A, Mönkemüller K, Malfertheiner P
    Short-term/low-dose aspirin-induced duodenal erosions are not dependent on Helicobacter pylori infection, cyclooxygenase expression and prostaglandin E2 levels
    Scand J Gastroenterol. 2008;43(7):801-9.
  33. Vermehren J, Kau A, Gärtner BC, Göbel R, Zeuzem S, Sarrazin C
    Differences between two real-time PCR-based hepatitis C virus (HCV) assays (RealTime HCV and Cobas AmpliPrep/Cobas TaqMan) and one signal amplification assay (Versant HCV RNA 3.0) for RNA detection and quantification
    J Clin Microbiol 2008;46(12):3880-91
  34. Wasmuth HE, Zaldivar MM, Berres ML, Werth A, Scholten D, Hillebrandt S, Tacke F, Schmitz P, Dahl E, Wiederholt T, Hellerbrand C, Berg T, Weiskirchen R, Trautwein C, Lammert F
    The fractalkine receptor CX3CR1 is involved in liver fibrosis due to hepatitis C infection
    J Hepatol 2008;48(2):208-215
  35. Weiskirchen R, Lammert F
    A yellow bullet against the drivers of hepatic fibrogenesis
    Hepatology 2008; 48 (2): 683-685
  36. Welsch C, Domingues FS, Susser S, Antes I, Hartmann C, Mayr G, Schlicker A, Sarrazin C, Albrecht M, Zeuzem S, Lengauer T
    Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus
    Genome Biol. 2008 Jan 23;9(1):R16
  37. Wex T, Kuester D, Vieth M, Treiber G, Krieg A, Roessner A, Malfertheiner P
    Helicobacter pylori infection and short-term intake of low-dose aspirin have different effects on alpha-1 antitrypsin/alpha-1 peptidase inhibitor (alpha1-PI) levels in antral mucosa and peripheral blood
    Scand J Gastroenterol. 2008;43(10):1194-201
  38. Zimmer V, Rädle J
    Endoscopic view of appendicitis
    Mayo Clin Proc 2008;83(6):622
  39. Zinkiewicz K, Majewski M, Krawczyk M, Zgodzinski W, Skoczylas T, Wallner G
    Dysphagia and retrosternal pain related to a round plastic foreign body impacted in the esophageal wall for over 20 years
    Endoscopy. 2008 Sep;40 Suppl 2:E160
  40. Zúñiga S, Molina H, Azocar L, Amigo L, Arrese M, Nervi F, Lammert F, Miquel JF
    Ezetimibe prevents cholesterol gallstone formation in mice
    Liver Int 2008 Aug;28(7):935-47

Übersichtsartikel

  1. Biecker E, Heller J, Schmitz V, Lammert F, Sauerbruch T
    Effiziente Diagnostik und Therapie gastrointestinaler Blutungen
    Dt Ärztebl 2008;105(5):85-93
  2. Dauer M, Schnurr M, Eigler A
    Dendritic cell-based cancer vaccination: quo vadis?
    Expert Rev Vaccines. 2008 Sep;7(7):1041-53
  3. Hall R, Lammert F
    Genetic determinants of liver fibrogenesis: a systems genetics approach in recombinant inbred mice.
    In: Bosch J, Burroughs AK, Lammert F, Lebrec D, Sauerbruch T (Hrsg.)
    Liver cirrhosis: from pathophysiology to disease management
    Springer, Dordrecht 2008, S. 70-74
  4. Herrmann E, Zeuzem S
    Ribavirin plus either peginterferon alpha-2a or peginterferon alpha-2b for patients with chronic HCV infection?
    Nat Clin Pract Gastr 2008 Jul;5(7):362-3. Epub 2008 May 27.
  5. Höblinger A, Lammert F
    Genetics of biliary tract diseases: new insights into gallstone disease and biliary tract cancers
    Curr Opin Gastroen 2008;24(3):363-371
  6. Lammert F, Miquel JF
    Gallstone disease: from genes to evidence-based therapy
    J Hepatol 2008;48(S1):S124-S135
  7. Laufs U, Lammert F
    Fettstoffwechselstörungen in der Schwangerschaft
    Dtsch Med Wochenschr 2008; 133 (42): 2173-2176
  8. Pohl D, Fox M, Fried M, Göke B, Prinz C, Mönnikes H, Rogler G, Dauer M, Keller J, Lippl F, Schiefke I, Seidler U, Allescher HD, Kandahar Study Group
    Do we need gastric acid?
    Digestion. 2008;77(3-4):184-97
  9. Rädle J
    Endoskopie-Ausbildung in der Gastroenterologie – Neue Wege durch strukturierte Kursmodule
    Der Gastroenterologe 2008;3:428-30
  10. Treiber G, Wex T, Schleyer E, Tröger U, Hosius C, Malfertheiner P
    Imatinib for hepatocellular cancer – Focus on pharmacokinetic/ pharmacodynamic modelling
    Cancer Lett 2008;260(1-2):146-154
  11. Weber S., Gressner O.A., Hall R., Grünhage F., Lammert F
    Genetic determinants in hepatic fibrosis: from experimental models to fibrogenic gene signatures in humans
    Clin Liver Dis 2008;12(4):747-57
  12. Weber S, Lammert F
    Leberfibrose: genetische Tests für polygene Erkrankungen?
    Med Welt 2009; 59 (12): 481-485
  13. Weber S, Lammert F
    Of Mice and Men: Systemgenetik der Leberfibrose
    Magazin Forschung 2008(2): 20-23

Buchbeiträge

  1. Bosch J, Burroughs AK, Lammert F, Lebrec D, Sauerbruch T (Hrsg.)
    Liver cirrhosis: from pathophysiology to disease management
    Springer, Dordrecht 2008
  2. Jüngst C, Lammert F
    Physiologie und Pathophysiologie des Gallensäurenstoffwechsels und der Gallesekretion
    In: Riemann JF, Fischbach W, Galle PR, Mössner J (Hrsg.)
    Gastroenterologie in Klinik und Praxis
    Georg Thieme Verlag, Stuttgart 2008, S. 1671-1679
  3. Lammert F., Neubrand M.W., Sauerbruch T
    Cholezystolithiasis
    In: Riemann JF, Fischbach W, Galle PR, Mössner J (Hrsg.)
    Gastroenterologie in Klinik und Praxis
    Georg Thieme Verlag, Stuttgart 2008, S. 1694-1702
  4. Lammert F, Sauerbruch T
    Pathogenesis of gallstone formation. In: Carey MC, Díte P, Gabryelewicz A, Keim V, Mössner J (Hrsg.)
    Future Perspectives in Gastroenterology
    Springer, Dordrecht 2008, S. 99-107
  5. Weber S, Grünhage F, Lammert F
    ABCG5/G8 as a human risk gene for cholesterol gallstone disease
    FALK Symposium 165; 2008: 229-234