Publikationen

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2022

Marcel Meyerheim, Norbert Graf, Anna Burns-Gebhart, Annette Sander

The MyPal-Child study: Design and preliminary outcomes (Chapter 6).

In: The European MyPal study: Developing digital health for adults and children with cancer. Edts.: Sheila Payne, Yakubu Salifu, Dunja Begovic, and Anthony Greenwood. eBook: 2022, pp 47-58. https://mypal-project.eu/wp-content/uploads/MyPal-ebook-FINAL.pdf  -> Book

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Gordan M. Vujanic,  Norbert Graf, Ellen D'Hooghe, Tanzina Chowdhury,  Christian Vokuhl, Reem Al-Saadi, Kathy Pritchard-Jones,  Patrick Melchior,  Rhoikos Furtwängler

Outcomes of patients with Wilms' tumour stage III due to positive resection margins only: An analysis of patients treated on the SIOP-WT-2001 protocol in the UK-CCLG and GPOH studies

Int J Cancer, 2022; DOI: 10.1002/ijc.34371  -> Paper

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Van den Heuvel-Eibrink M, Fernandez CV, Graf N, GellerJI

Progress by international collaboration for pediatric renal tumors by HARMONIzation and COllaboration: The HARMONICA initiative

Ped Blood & Cancer 2022, DOI: 10.1002/pbc.30082  -> Paper

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Graf N, Furtwängler R, Stein R

Nierentumoren beim Kind  

In: Michel, M.S., Thüroff, J.W., Janetschek, G., Wirth, M.P. (eds) Die Urologie. Springer Reference Medizin. Springer, Berlin, Heidelberg; 2022; doi.org/10.1007/978-3-642-41168-7_196-2 -> Paper

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Nils Welter, Jack Brzezinski, Amy Treece, Murali Chintagumpala, Matthew D. Young, Daniela Perotti, Kathleen Kieran, Marjolijn C.J. Jongmans, Andrew J. Murphy

The pathophysiology of bilateral and multifocal Wilms tumors: What we can learn from the study of predisposition syndromes 

Pediatr Blood Cancer 2022 Sep 12;e29984; doi: 10.1002/pbc.29984. Online ahead of print -> Paper

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Mergen M, Scheid S, Schubmehl H, Backens M, Reith W, Graf N

Cranial MRI in Childhood Acute Leukemia during Treatment and Follow-up Including the Impact of Intrathecal MTX - A Single Center Study and Review of the Literature  

Cancers 2022, 14, 4688 https://doi.org/10.3390/cancers14194688 -> Paper

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Welter N, Brzezinski J, Treece A, Chintagumpala M, Young MD, Perotti D, Kieran K, Jongmans MCJ, Murphey AJ

The pathophysiology of bilateral and multifocal Wilms tumors: What we can learn from the study of predisposition syndromes

Pediatr Blood Cancer. 2022;e29984; doi: 10.1002/pbc.29984 -> Paper

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Norbert Graf, Rhoikos Furtwängler und Raimund Stein

Tumoren der Blase und der Prostata beim Kind

M. S. Michel et al. (Hrsg.), Die Urologie, Springer Reference Medizin; DOI: 10.1007/978-3-642-41168-7_205-2-> Paper

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Papan C, Argentiero A, Adams O, Porwoll M, Hakim U, Farinelli E, Testa I, Pasticci MB, Mezzetti D, Perruccio K, SimonA, Liese JG, Knuf M, Stein M, Yacobov R, Bamberger E, Schneider S, Esposito S, Tenenbaum T
Association of viral load with TRAIL, IP‐10, CRP biomarker signature and disease severity in children withrespiratory tract infection or fever without source: a prospective, multicentre cohort study
J Med Virol 2022;1‐11; doi:10.1002/jmv.28113 -> Paper

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Lisa Eisenberg, the XplOit consortium, Christian Brossette, Jochen Rauch, Andrea Grandjean, Hellmut Ottinger, Jürgen Rissland, Ulf Schwarz, Norbert Graf, Dietrich W. Beelen, Stephan Kiefer, Nico Pfeifer, Amin T. Turki

Time-dependent prediction of mortality and cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation using machine learning

Am J Hematol 2022; https://doi.org/10.1002/ajh.26671 -> Paper

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Meier Clemens Magnus, Fuchs Jörg, von Schweinitz Dietrich, Stein Raimund, Wagenpfeil Stefan, Kager Leo, Schenk Jens-Peter, Vokuhl Christian, Melchior Patrick, Welter Nils, Furtwängler Rhoikos, Graf Norbert

Surgical Factors Influencing Local Relapse and Outcome in the Treatment of Unilateral Nephroblastoma

Annals of Surgery: August 26, 2022 – published ahead of print; doi: 10.1097/SLA.0000000000005690 -> Paper

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Clemens-Magnus Meier, Rhoikos Furtwängler, Dietrich von Schweinitz, Raimund Stein, Nils Welter, Stefan Wagenpfeil, Leo Kager, Jens-Peter Schenk, Christian Vokuhl, Patrick Melchior, Jörg (Joerg) Fuchs, Norbert Graf

Vena Cava Thrombus in Patients with Wilms Tumor

Cancers 2022, 14, 3924; https://doi.org/10.3390/cancers14163924 -> Paper

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Kasra Mirzaie, Anna Burns-Gebhart, Marcel Meyerheim, Annette Sander, Norbert Graf

Emotion Regulation Flexibility and Electronic Patient-Reported Outcomes: A Framework for Understanding Symptoms and Affect Dynamics in Pediatric Psycho-Oncology

Cancers 14, 3874, 2022; https://doi.org/10.3390/cancers14163874 -> Paper

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Welter N, Furtwängler R, Schneider G, Graf N, Schenk J-P

Tumorprädispositionssyndrome und Nephroblastom

Radiologie 2022; https://doi.org/10.1007/s00117-022-01056-w -> Paper

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Hess S, Poryo M, Böttger R, Franz A, Klotz D, Linnemann K, Ott T, Pöschl J, Schroth M, Stein A, Ralser E, Reutter H, Thome UH, Wieg C, Ehrlich A, Ruckes C, Wagenpfeil S, Zemlin M, Papan C, Simon A, Bay J, Meyer S

Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight < 1250 g : Results from a survey in Austria and Germany

Wien Med Wochenschr 2022; doi: 10.1007/s10354-022-00952-z. Epub ahead of print -> Paper

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Kramer A, Monsef I, Rücker G, Rupp J, Scheithauer S, Schmucker C, Simon A, Mutters NT

The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis

BMC Infect Dis 22(1):587, 2022; doi: 10.1186/s12879-022-07554-5 -> Paper

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Dominik T. Schneider, Tabea Blessing, Norbert Graf, Michael Abele, Ines B. Brecht, Thorsten Rosenbaum

Tumorerkrankungen im Kontext von Störungen von Wachstum und Entwicklung

Monatsschr Kinderhlkd, 2022; doi.org/10.1007/s00112-022-01540-6&nbsp; -> Paper

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Maximilian David Mauritz, Carola Hasan, Pia Schmidt, Arne Simon, Markus Knuf, Boris Zernikow

Lower Respiratory Tract Infections in Pediatric Patients with Severe Neurological Impairments: Clinical Observations and Perspectives in a Palliative Care Unit 

Children 9,852, 2022; doi.org/10.3390/children9060852&nbsp; -> Paper

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Norbert Graf, Rhoikos Furtwängler, Raimund Stein

Hodentumoren beim Kind

M. S. Michel et al. (Hrsg.), Die Urologie, Springer Reference Medizin; doi.org/10.1007/978-3-642-41168-7_186-2 -> Buchbeitrag

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Teresa Marta Cardesa-Salzmann, Bernhard Stephan, Arne Simon, Rhoikos Furtwängler, Dominik Schöndorf, Sabine Heine, Eyad Torfah, Margaux Lux, Sonja Meyer, Norbert Graf

Immune-mediated thrombotic thrombocytopenic purpura in a Jehovah’s Witness – Effectiveness of incorporating extracorporeal immunoadsorption to caplacizumab, steroids and rituximab

Clinical Case Reports 2022; doi.org/10.1002/ccr3.5902 -> Paper

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Thomas J. Jackson, Herve J. Brisse, Kathy Pritchard-Jones, Kayo Nakata, Carlo Morosi, Takahara Oue, Sabine Irtan, Gordan Vujanic, Marry M. van den Heuvel-Eibrink, Norbert Graf, Tanzina Chowdhury

How we approach paediatric renal tumour core needle biopsy in the setting of preoperative chemotherapy: A Review from the SIOP Renal Tumour Study Group

Pediatric Blood & Cancer e29702, 2022; DOI: 10.1002/pbc.29702 -> Paper

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Karolina Nemes, Pascal D. Johann, Mona Steinbügl, Miriam Gruhle, Susanne Bens, Denis Kachanov, Margarita Teleshova, Peter Hauser, Thorsten Simon, Stephan Tippelt, Wolfgang Eberl, Martin Chada, Vicente Santa-Maria Lopez, Lorenz Grigull, Pablo Hernáiz-Driever, Matthias Eyrich, Jane Pears,Till Milde, Harald Reinhard, Alfred Leipold, Marianne van de Weterin, Maria João Gil-da-Costa,Georg Ebetsberger-Dachs, Kornelius Kerl, Andreas Lemmer, Heidrun Boztug, Rhoikos Furtwängler, Uwe Kordes, Christian Vokuhl, Martin Hasselblatt, Brigitte Bison, Thomas Kröncke, Patrick Melchior, Beate Timmermann, Joachim Gerss, Reiner Siebert, Michael C. Frühwald

Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors(eMRT) in the EU-RHAB Registry: A Unique and Challenging Population

Cancers 2022,14, 2185; doi.org/10.3390/cancers14092185 -> Paper

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Joaquim Caetano de Aguirre-Neto, Beatriz de Camargo, Harm van Tinteren, Christophe Bergeron, Jesper Brok, Gema Ramírez-Villar, Arnauld Verschuur, Rhoikos Furtwängler, Lisa Howell, Daniel Saunders, Oystein Olsen, Aurore Coulomb, Christian Vokuhl, Jan Godzinski, Anne M. Smets, Gordan M. Vujanic, Marry M. van den Heuvel-Eibrink, Norbert Graf, Kathy Pritchard-Jones

International Comparisons of Clinical Demographics and Outcomes in the International Society of Pediatric Oncology Wilms Tumor 2001 Trial and Study 

JCO Global Oncology 2022 :8; ascopubs.org/doi/10.1200/GO.21.00425 -> Paper

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J. Holstiege, J. Bätzing, M. K. Akmatov, R. Tillmann, M. Hufnagel, J. Hübner, R. Berner, A. Simon

Rückgang der ambulanten Antibiotikaverordnungen bei Kindern und Jugendlichen in Deutschland 2010–2019. Regionale Entwicklung in den deutschen KV-Regionen

Monatsschr Kinderheilkd 170, 392–402, 2022; doi:10.1007/s00112-021-01276-9 -> Paper

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Pengbo Beck, Barbara Selle, Lukas Madenach, David T W Jones, Christian Vokuhl, Apurva Gopisetty, Arash Nabbi, Ines B Brecht, Martin Ebinger, Jenny Wegert, Norbert Graf, Manfred Gessler, Stefan M Pfister, Natalie Jäger 

The genomic landscape of pediatric renal cell carcinomas

iScience 25, 104167, 2022; doi: 10.1016/j.isci.2022.104167  -> Paper

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J.N. van der Beek, T.A. Watson, R.A.J. Nievelstein, H.J. Brisse, C. Morosi, H.M. Lederman, A. Coma, M.M. Gavra, K. Vult von Steyern, K. Lakatos, L. Breysem, E. Varga, H. Ducou Le Pointe, M.H. Lequin, J.F. Schäfer, H.-J. Mentzel, A.M. Hötker, G. Calareso, S. Swinson, M. Kyncl, C. Granata, M. Aertsen, P.L. Di Paolo, R.R. de Krijger, N. Graf, Ø.E. Olsen, J.P. Schenk, M.M. van den Heuvel-Eibrink, A.S. Littooij

MRI-characteristics of Pediatric Renal Tumors: a SIOP-RTSG Radiology panel Delphi Study

J Magn Reson Imaging. 55:543-552, 2022; doi: 10.1002/jmri.27878  -> Paper

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Cornelis van Tilburg, Elke Pfaff, Kristian Pajtler, Karin Langenberg, Petra Fiesel, Barbara Jones, Gnana Prakash Balasubramanian, Sebastian Stark, Pascal Johann, Mirjam Blattner-Johnson, Kathrin Schramm, Nicola Dikow, Steffen Hirsch, Christian Sutter, Kerstin Grund, Arend von Stackelberg, Andreas Kulozik, Andrej Lissat, Arndt Borkhardt, Roland Meisel, Dirk Reinhardt, Jan-Henning Klusmann, Gudrun Fleischhack, Stephan Tippelt, Dietrich von Schweinitz, Irene Schmid, Christof Kramm, André von Bueren, Gabriele Calaminus, Peter Vorwerk, Norbert Graf, Frank Westermann, Matthias Fischer, Angelika Eggert, Birgit Burkhardt, Wilhelm Wößmann, Michaela Nathrath, Stefanie Hecker-Nolting, Michael Frühwald, Dominik Schneider, Ines Brecht, Petra Ketteler, Simone Fulda, Ewa Koscielniak, Michael Meister, Monika Scheer, Simone Hettmer, Matthias Schwab, Roman Tremmel, Ingrid Øra, Caroline Hutter, Nicolas Gerber, Olli Lohi, Bernarda Kazanowska, Antonis Kattamis, Maria Filippidou, Bianca Goemans, C. Michel Zwaan, Till Milde, Natalie Jäger, Stephan Wolf, David Reuss, Felix Sahm, Andreas von Deimling, Uta Dirksen, Angelika Freitag, Ruth Witt, Peter Lichter, Annette Kopp-Schneider, David Jones, Jan Molenaar, David Capper, Stefan Pfister, and Olaf Witt

The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets

Cancer Discovery11:2764-2779, 2021 doi: 10.1158/2159-8290.CD-21-0094 -> Paper

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van der Perk MEM, Cost NG, Bos AME, Brannigan R, Chowdhury T, Davidoff AM, Daw NC, Dome JS, Ehrlich P, Graf N, Geller J, Kalapurakal J, Kieran K, Malek M, McAleer MF, Mullen E, Pater L, Polanco A, Romao R, Saltzman AF, Walz AL, Woods AD, van den Heuvel-Eibrink MM, Fernandez CV 

White paper: Onco-fertility in pediatric patients with Wilms tumor

Int J Cancer 2022; doi: 10.1002/ijc.34006 -> Paper

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Norbert Graf, Rhoikos Furtwängler, Raimund Stein

Neuroblastome in der Pädiarischen Urologie

In: M. S. Michel et al. (Hrsg.), Die Urologie, Springer Reference Medizin; doi: 10.1007/978-3-642-41168-7_193-2 -> Paper

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Karsten Theiß, Arne Simon, Norbert Graf, Tilman Rohrer

Die 1. COVID-19 Welle in den saarländischen Kinder- und Jugendarztpraxis

Saarländisches Ärzteblatt 5:14-23, 2022 -> Paper

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Pia Schmidt, Carola Hasan, Maximilian D Mauritz, Arne Simon, Kathrin Stening, Almut Hartenstein-Pinter, Boris Zernikow, Julia Wager

Multidrug-resistant organisms in paediatric palliative care patients – Prevalence, risk factors and the impact of a liberal hygiene concept

Journal of Paediatrics and Child Health (2022); doi: 10.1111/jpc.15980 -> Paper

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Commission for Hospital Hygiene and Infection Prevention (KRINKO) (Prof. Dr. Simon ist der Koordinator der entsprechenden KRINKO Arbeitsgruppe)

Infection prevention requirements for the medical care ofimmunosuppressed patients: recommendations of the Commission forHospital Hygiene and Infection Prevention (KRINKO) at the Robert KochInstitute

GMS Hyg Infect Control. 2022;17:Doc07; doi: 10.3205/dgkh000410, URN: urn:nbn:de:0183-dgkh00041-> Paper

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William Mifsud, Rhoikos Furtwängler, Christian Vokuhl, Ellen D’Hooghe, Kathy Pritchard-Jones, Norbert Graf, Gordan M. Vujanic

Treatment of patients with stage I focal anaplastic and diffuse anaplastic Wilms tumour: A report from the SIOP-WT-2001 GPOH and UK-CCLG studies

Eur J Cancer 166:1-7, 2022; doi: 10.1016/j.ejca.2022.01.036 -> Paper

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Oliver Zolk, Annika von dem Knesebeck, Norbert Graf, Thorsten Simon, Barbara Hero, Hashim Abdul-Khaliq, Mohamed Abd El Rahman, Claudia Spix, Benjamin F.B. Mayer, Susanne Elsner, Judith Gebauer, Thorsten Langer

Cardiovascular Health Status And Genetic Risk In Survivors of Childhood Neuroblastoma and Nephroblastoma Treated With Doxorubicin: Protocol of the Pharmacogenetic Part of the LESS-Anthra Cross-Sectional Cohort Study

JMIR Res Protoc 2022;11(2):e27898; doi: 10.2196/27898  -> Paper

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Alissa Groenendijk, Harm van Tinteren, Yilin Jiang, Ronald R de Krijger, Gordan M Vujanic, Jan Godzinski, Christian Rübe, Jens-Peter Schenk, Carlo Morosi, Kathy Pritchard-Jones, Reem Al-Saadi, Sucheta J Vaidya, Arnauld C Verschuur, Gema L Ramírez-Villar, Norbert Graf, Beatriz de Camargo, Jarno Drost, Daniela Perotti, Marry M van den Heuvel-Eibrink, Jesper Brok, Filippo Spreafico, Annelies M.C Mavinkurve-Groothuis 

Outcome of SIOP patients with low- or intermediate-risk Wilms tumor relapsing after initial vincristine and actinomycin-D therapy only − the SIOP 93-01 and 2001 protocols

Eur J cancer 163:88-97, 2022; doi: 10.1016/j.ejca.2021.12.014 -> Paper

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Cardesa-Salzmann TM, Simon A, Graf N

Antibiotics in early life and childhood pre-B-ALL. Reasons to analyze a possible new piece in the puzzle

Discover Oncology 13:5, 2022; doi: 10.1007/s12672-022-00465 -> Paper

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Sandy Schlage, Thomas Lehrnbecher, Reinhard Berner, Arne Simon, Nicole Toepfner 

SARS-CoV-2 in pediatric cancer: a systematic review 

Eur J Pediatr 2022; doi: 10.1007/s00431-021-04338-y -> Paper

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2021
 

Gordan Vujanic, Ellen D'Hooghe, Norbert Graf, Christian Vokuhl, Reem Al-Saadi, Tanzina Chowdhury, Rhoikos Furtwaengler, Kathy Pritchard-Jones

Prognostic significance of histopathological response to preoperative chemotherapy in unilateral Wilms Tumor: An analysis of 899 patients treated on the SIOP WT 2001 protocol in the UK CCLG and GPOH studies

Int J Cancer 149:1332-1340, 2021; 10.1002/ijc.33707  -> Paper
 

Janna Hol, Rosalyn Jewell, Tanzina Chowdhury, Catriona Duncan, Kayo Nakata, Takaharu Oue, Marion Gauthier-Villars, Annemieke S. Littooij, Yasuhiko Kaneko, Norbert Graf, Franck Bourdeaut, Marry M. van den Heuvel-Eibrink, Kathy Pritchard-Jones, Eamonn R. Maher, Christian P. Kratz, Marjolijn C. J. Jongmans

Wilms tumor surveillance in at-risk children: literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumor Study Group

Eur J Cancer 153:51-63, 2021; doi: 10.1016/j.ejca.2021.05.014  -> Paper
 

Schenk JP, Hötker A, Furtwängler R, Fuchs J, Warmann SW, Graf N

Bildgebung renaler Tumoren im Kindesalter

Radiologe. 61:619-628, 2021; doi: 10.1007/s00117-021-00864-w  -> Paper
 

A. Groenendijk,F. Spreafico, R. de Krijger, J. Drost, J. Brok, D. Perotti, H. van Tinteren, R. Venkatramani, J. Godzinski, C. Rübe, J.J. Geller, N. Graf, M.M. van den Heuvel-Eibrink and A.M.C. Mavinkurve- Groothuis

Prognostic factors for Wilms Tumor recurrence: a review of the literature

Cancers 13:3142, 2021; doi: 10.3390/cancers13133142  -> Paper
 

Stefan Hoffmann, Robert Schraut, Thomas Kröll, Wiebke Scholz, Tatiana Belova, Johann Erhardt, Daniel Gollmer, Christian Mauck, Giorgos Zacharioudakis, Marcel Meyerheim, Panos Bonotis, Christine Kakalou, Maria Chatzimina, Christina Karamanidou, Annette Sander, Jana Didi, Norbert Graf, Pantelis Natsiavas

AquaScouts: ePROs implemented as a serious game for children with cancer

Frontiers in Digital Health 3:164, 2021; doi: 10.3389/fdgth.2021.730948  -> Paper
 

Egle L, Sauter K, Ockfen S, Haber M, Becker S, Wagenpfeil G, Zemlin M, Meyer S, Simon A

Retrospective audit of antibiotic use in a university general pediatrics department using hospital pharmacy dispensing data 

GMS Infect Dis 2021;9:Doc06; doi: 10.3205/id0000 -> Paper
 

Anna-Lisa Sorg, Veronika Kaiser, Selina Becht, Arne Simon, Rüdiger von Kries

Impact of School Closures on the Proportion of Children in the COVID-19 Pandemic: An Example from the Winter Lockdown in Germany

Klin Padiatr  2021 Nov 19; doi: 10.1055/a-1594-2818 -> Paper
 

Papan C, Argentiero A, Porwoll M, Hakim U, Farinelli E, Testa I, Pasticci MB, Mezzetti D, Perruccio K, Etshtein L, Mastboim N, Moscoviz E, Ber TI, Cohen A, Simon E, Boico O, Shani L, Gottlieb TM, Navon R, Barash E, Oved K, Eden E, Simon A, Liese JG, Knuf M, Stein M, Yacobov R, Bamberger E, Schneider S, Esposito S, Tenenbaum T

A host signature based on TRAIL, IP-10, and CRP for reducing antibiotic overuse in children by differentiating bacterial from viral infections: A prospective, multicentre cohort study

Clin Microbiol Infect. 2021 Nov 9:S1198-743X(21)00621-2. doi: 10.1016/j.cmi.2021.10.019 -> Paper
 

Ovidio Jiménez Martin, Andreas Schlosser, Rhoikos Furtwängler, Jenny Wegert, Manfred Gessler

MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates

Cancer Cell Int 21:555, 2021; doi: 10.1186/s12935-021-02259-2 -> Paper
 

Madline P Gund, Gabor Boros, Matthias Hannig, Sigrid Thieme-Ruffing, Barbara Gärtner, Tilman R Rohrer, Arne Simon, Stefan Rupf

Bacterial contamination of forehead skin and surgical mask in aerosol-producing dental treatment

Journal of Oral Microbiology 13 (1):2021; doi: 10.1080/20002297.2021.1978731  -> Paper
 

Nils Welter, Angelo Wagner, Rhoikos Furtwängler, Patrick Melchior, Leo Kager, Christian Vokuhl, Jens-Peter Schenk, Clemens Magnus Meier, Stefan Siemer, Manfred Gessler, Norbert Graf

Characteristics of Nephroblastoma/Nephroblastomatosis in Children with a Clinically Reported Underlying Malformation or Cancer Predisposition Syndrome 

Cancers, 13 (19) 5016, 2021; doi: 110.3390/cancers13195016 -> Paper
 

Norbert Graf, Christophe Bergeron, Jesper Brok, Beatriz de Camargo, Tanzina Chowdhury, Rhoikos Furtwängler, Manfred Gessler, Jan Godzinski, Kathy Pritchard-Jones, Gema Ramirez, Christian Rübe, Bengt Sandstedt, Jens-Peter Schenk, Filippo Spreafico, Hélène Sudour-Bonnange, Harm van Tinteren, Arnauld Verschuur, Gordan Vujanic, Marry M. van den Heuvel-Eibrink

Fifty years of clinical and research studies for childhood renal tumors within the International Society of Pediatric Oncology (SIOP) 

Annals of Oncology 2021; doi: 10.1016/j.annonc.2021.08.1749  -> Paper
 

Marcel Meyerheim, Anna Burns-Gebhart, Kasra Mirzaie, Tina Garani-Papadatos, Yvonne Braun, Norbert Graf

Challenges and Pitfalls for Implementing Digital Health Solutions in Clinical Studies in Euro

Front. Digit. Health, 28 September 20; doi: 10.3389/fdgth.2021.730680 -> Paper
 

Cornelis van Tilburg, Elke Pfaff, Kristian W Pajtler, Karin P S Langenberg, Petra Fiesel, Barbara C Jones, Gnana Prakash Balasubramanian, Sebastian Stark, Pascal D Johann, Mirjam Blattner-Johnson, Kathrin Schramm, Nicola Dikow, Steffen Hirsch, Christian Sutter, Kerstin Grund, Arend von Stackelberg, Andreas E Kulozik, Andrej Lissat, Arndt Borkhardt, Roland Meisel, Dirk Reinhardt, Jan-Henning Klusmann, Gudrun Fleischhack, Stephan Tippelt, Dietrich von Schweinitz, Irene Schmid, Christof M Kramm, Andre O von Bueren, Gabriele Calaminus, Peter Vorwerk, Norbert Graf, Frank Westermann, Matthias Fischer, Angelika Eggert, Birgit Burkhardt, Wilhelm Wossmann, Michaela Nathrath, Stefanie Hecker-Nolting, Michael C Fruhwald, Dominik T Schneider, Ines B Brecht, Petra (Temming) Ketteler, Simone Fulda, Ewa Koscielniak, Michael T Meister, Monika Scheer, Simone Hettmer, Matthias Schwab, Roman Tremmel, Ingrid Ora, Caroline Hutter, Nicolas U Gerber, Olli Lohi, Bernarda Kazanowska, Antonis Kattamis, Maria Filippidou, Bianca Goemans, Till Milde, Natalie Jager, Stephan Wolf, David Reuss, Felix Sahm, Andreas von Deimling, Uta Dirksen,Angelika Freitag, Ruth Witt, Peter Lichter, Annette Kopp-Schneider, David T.W. Jones, Jan J. Molenaar, David Capper,Stefan M Pfister, Olaf Witt

The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets

Cancer Discovery 2021; doi: 10.1158/2159-8290.CD-21-0094  -> Paper
 

Zolk O, von dem Knesebeck, Graf N, Simon T, Hero B, Abdul-Khaliq H, Abd El Rahman, Spix C, Mayer B, Elsner S, Gebauer J, Langer

Cardiovascular health status and genetic risk in survivors of childhood neuroblastoma and nephroblastoma treated with doxorubicin: protocol of the pharmacogenetic part of the LESS-Anthra cross-sectional cohort study

JMIR Research Protocols, 2021; https://preprints.jmir.org/preprint/27898/ -> Paper
 

Leonie Egle, Katharina Sauter, Svenja Ockfen, Manfred Haber, Sören Becker, Gudrun Wagenpfeil, Hashim Abdul-Khaliq, Jochen Pfeifer, Harald Sauer, Arne Simon

Retrospektives Audit des Antibiotikaverbrauchs in einer universitären Kinderkardiologie auf der Grundlage von Apothekenlieferdaten

Krankenhauspharmazie 42:345–52 -> Paper
 

Susanna Esposito, Bahaa Abu-Raya, Paolo Bonanni, Fabianne Cahn-Sellem, Katie L. Flanagan, Federico Martinon Torres, Asuncion Mejias, Simon Nadel, Marco A. P. Safadi, Arne Simon on behalf of the World Association for Infectious Diseases Immunological Disorders (WAidid)

Coadministration of Anti-Viral Monoclonal Antibodies With Routine Pediatric Vaccines and Implications for Nirsevimab Use: A White Paper

Front. Immunol., 11 August 2021; doi: 10.3389/fimmu.2021.708939 -> Abstract
 

J.N. van der Beek, T.A. Watson, R.A.J. Nievelstein, H.J. Brisse, C. Morosi, H.M. Lederman, A. Coma, M.M. Gavra, K. Vult von Steyern, K. Lakatos, L. Breysem, E. Varga, H. Ducou Le Pointe, M.H. Lequin, J.F. Schäfer, H.-J. Mentzel, A.M. Hötker, G. Calareso, S. Swinson, M. Kyncl, C. Granata, M. Aertsen, P.L. Di Paolo, R.R. de Krijger, N. Graf, Ø.E. Olsen, J.P. Schenk, M.M. van den Heuvel-Eibrink, A.S. Littooij

MRI-characteristics of Pediatric Renal Tumors: a SIOP-RTSG Radiology panel Delphi Study.

Journal of Magnetic Resonance Imaging, first published 6. August 2021: doi.org/10.1002/jmri.27878&nbsp; -> Abstract
 

Mergen M, Graf N, Scheid S, Schubmehl H, Backens M and Reith W

Changes of Intracerebral Ventricular Width in Children with Leukemia at Diagnosis, During Treatment and in Follow-Up

Austin J Radiol. 2021; 8(7): 1148  -> Full Text
 

Svenja Ockfen, Leonie Egle, Katharina Sauter, Manfred Haber, Sören Becker, Gudrun Wagenpfeil, Norbert Graf, Arne Simon

Meropenem Use in Pediatric Oncology – Audit on Indication, Appropriateness and Consumption Comparing Patient Derived and Pharmacy Dispensing Data

Klin Padiatr, 2021; doi: 10.1055/a-1481-8905  -> Abstract
 

A. Groenendijk,F. Spreafico, R. de Krijger, J. Drost, J. Brok, D. Perotti, H. van Tinteren, R. Venkatramani, J. Godzinski, C. Rübe, J.J. Geller, N. Graf, M.M. van den Heuvel-Eibrink, A.M.C. Mavinkurve- Groothuis

Prognostic factors for Wilms Tumor recurrence: a review of the literature

Cancers 13 3142, 2021; doi: 10.3390/cancers13133142 -> Abstract
 

J-P Schenk, A Hötker, R Furtwängler, J Fuchs, S Warmann, N Graf

Bildgebung renaler Tumoren im Kindesalter 

Radiologe, 2021; doi: 10.1007/s00117-021-00864-w -> Abstract
 

Janna A. Hol, Rosalyn Jewell, Tanzina Chowdhury, Catriona Duncan, Kayo Nakata, Takaharu Oue, Marion Gauthier-Villars, Annemieke S. Littooij, Yasuhiko Kaneko, Norbert Graf, Franck Bourdeaut, Marry M. van den Heuvel-Eibrink, Kathy Pritchard-Jones, Eamonn R. Maher, Christian P. Kratz, Marjolijn C.J. Jongmans

Wilms tumour surveillance in at-risk children: Literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumour Study Group

European Journal of Cancer 153 (2021) 51e; doi: 10.1016/j.ejca.2021.05.014 -> Abstract
 

Gordan Vujanic, Ellen D'Hooghe, Norbert Graf, Christian Vokuhl, Reem Al-Saadi, Tanzina Chowdhury, Rhoikos Furtwaengler, Kathy Pritchard-Jones

Prognostic significance of histopathological response to preoperative chemotherapy in unilateral Wilms Tumor: An analysis of 899 patients treated on the SIOP WT 2001 protocol in the UK CCLG and GPOH studies

Int J Cancer, 2021; doi: 10.1002/ijc.337  -> Abstract

 

Simon A, Reinhardt T, Meyer S, Baltaci Y, Rissland J, Eichler H, Klemis V, Sester M, Graf N

COVID-19 in a pediatric cancer patient with T-lympho­blastic lymphoma: Response to convalescence plasma and subsequent induction of SARS-CoV-2 specific humoral and cellular immunity despite strong B-cell lymphopenia 

J Clin Images Med Case Rep. 2021; 2(3): 11  -> Paper
 

Arne Simon, Wolfgang Fahrendor, Guido Hitschmann

Preclinical evaluation of passive disinfection caps with a long-term catheter for the prevention of catheter-related bloodstream infection in pediatric cancer patients

GMS Hygiene and Infection Control 16:1-4, 2021; doi: 10.3205/dgkh000391  -> Abstract
 

Marcel Meyerheim, Christina Karamanidou, Sheila Payne, Tina Garani-Papadatos, Annette Sander, Julia Downing, Kostas Stamatopoulos, J Ling, Cathy Payne, Lydia Scarfò, Petr Lokaj, Christos Maramis, Norbert Graf

MyPal-Child study protocol: an observational prospective clinical feasibility study of the MyPal ePRO-based early palliative care digital system in paediatric oncology patients

BMJ Open 11:e045226, 2021; doi:10.1136/bmjopen-2020-045226 -> Abstract
 

Lina Driouk, Robert Schmitt, Anke Peters, Sabine Heine, Hermann Josef Girschick, Brigitte Strahm, Charlotte M. Niemeyer, Carsten Speckmann 

Daratumumab therapy for post-HSCT immune-mediated cytopenia: experiences from two pediatric cases and review of literature

Pediatrics 8:5, 2021 ; doi: 10.1186/s40348-021-00114-y   -> Abstract
 

Castagnola E, Bagnasco F, Mesini A, Agyeman PKA, Ammann RA, Carlesse F, Santolaya de Pablo ME, Groll AH, Haeusler GM, Lehrnbecher T, Simon A, D'Amico MR, Duong A, Idelevich EA, Luckowitsch M, Meli M, Menna G, Palmert S, Russo G, Sarno M, Solopova G, Tondo A, Traubici Y, Sung L 

Antibiotic Resistant Bloodstream Infections in Pediatric Patients Receiving Chemotherapy or Hematopoietic Stem Cell Transplant: Factors Associated with Development of Resistance, Intensive Care Admission and Mortality

Antibiotics (Basel) 10(3):266 2021. doi: 10.3390/antibiotics10030266 -> Abstract
 

Bochennek K, Simon A, Laws H-J, Groll AH, Lehrnbecher T

Fieber während der Granulozytopenie bei krebskranken Kindern und Jugendlichen 

Monatsschr Kinderheilkd 2021; doi: 10.1007/s00112-021-01146-4  -> Abstract
 

Andreas M. Hötker, Yousef Mazaheri, André Lollert, Jens-Peter Schenk, Junting Zheng, Oguz Akin, Norbert Graf, Gundula Staatz

Diffusion-weighted MRI and Histogram Analysis: Assessment of Response to Neoadjuvant Chemotherapy in Nephroblastoma

Abdominal Radiology 2021; doi:10.1007/s00261-021-03032-9; -> Abstract
 

Joeri Mul, Patrick Melchior, Enrica Seravalli, Daniel Saunders, StephanieBolle, Alison L. Cameron, Kristin Gurtner, Semi Harrabi, Yasmin Lassen-Ramshad, Naomi Lavan, Henriette Magelssen, Henry Mandeville, TomBoterberg, Petra S. Kroon, Alexis N.T.J. Kotte, Bianca A.W. Hoeben, PeterS.N. van Rossum, Martine van Grotel, Norbert Graf, Marry M. van den Heuvel-Eibrink, Christian Rübe, Geert O. Janssens

Inter-clinician delineation variation for a new highly-conformal flank targetvolume in children with renal tumors: A SIOP-Renal Tumor Study Group international multicenter exercise 

Clinical & Translational Radiation Oncology 28:39-47, 2021; doi: 10.1016/j.ctro.2021.03.001; -> Abstract
 

Sascha Meyer, Martin Poryo, Marina-Flotats Bastardas, Barbara Oehl-Jaschkowitz, Walter J. Schulz-Schaeffer, Ulrich Dillmann, Nasenien Nourkami-Tutdibi, Matthias Riemenschneider, Gerrit Fischer, Michael Zemlin, Daniel Ebrahimi-Fakhari, Sabine Heine, Eva Möhler, Tabea Reinardt, Robert Bals

Das Zentrum für Seltene Erkrankungen am UKS (ZSEUKS): Eine pädiatrische Perspektive

Saarländisches Ärzteblatt 4:18-27, 2021; -> Abstract
 

Karsten Theiß, Arne Simon, Norbert Graf, Tilman Rohrer

Management der ersten COVID-19-Welle in 45 Kinder- und Jugendarztpraxen im Saarland

Gesundheitswesen 83:1-72021; doi: 10.1055/a-1384-0568 -> Abstract
 

Arne Simon, Benjamin Siebald, Walther Stamm, Norbert Graf, Stephan Meier, Martin Schrappe, Andreas Groll, Hans-Jürgen Laws, Thomas Lernbecher

Schul- und Kindergartenbesuch und Heimunterricht bei Kindern mit Krebserkrankungen vor und während der SARS-CoV-2 Pandemie: Survey der Deutschen Gesellschaft für Pädiatrische Onkologie und Hämatologie

GMS Hyg Infect Control 16:Doc10, 2021; doi: 10.3205/dgkh000381  -> Abstract
 

Arne Simon, Johannes Forster, Johannes Liese

Antibiotic Stewardship (ABS) in der stationären Kinder- und Jugendmedizin

Pädiatrie up2date 16: 39–53, 2021; doi: 10.1055/a-0892-1155 -> Abstract
 

Toenges R, Greinix H, Lawitschka A, Halter J, Baumgartner A, Simon A, Arends J, Jäger P, Middeke M, Hilgendorf I, Klein S, Wagner-Drouet EM, Schmid C, Bug G, Wolff D 

Current practice in nutrition after allogeneic hematopoietic stem cell transplantation – results from a survey among hematopoietic stem cell transplant centers 

Clinical Nutrition, 2021; doi: 10.1016/j.clnu.2021.02.030  -> Abstract
 

van Peer SE, Pleijte CJH, de Krijger RR, Jongmans MCJ, Kuiper RP, Lilien MR, van Grotel M, Graf N, van den Heuvel-Eibrink MM, Hol JA

Clinical and Molecular Characteristics and Outcome of Cystic Partially Differentiated Nephroblastoma and Cystic Nephroma: A Narrative Review of the Literature

Cancers, 2021, 13, 997; doi: 10.3390/cancers13050 -> Abstract
 

Raquel Dávila Fajardo, Rhoikos Furtwängler, Martine van Grotel, Harm van Tinteren, Claudia Pasqualini, Kathy Pritchard-Jones, Reem Al-Saadi, Beatriz de Camargo, Gema L Ramírez Villar, Norbert Graf, Xavier Muracciole, Patrick Melchior, Daniel Saunders, Christian Rübe, Marry M van den Heuvel-Eibrink, Geert O Janssens, Arnauld C Verschuur

Outcome of stage IV completely necrotic Wilms tumour and local stage III treated according to the SIOP-2001 protocol 

Cancers, 2021, 13(5), 976; doi: 10.3390/cancers13050976 -> Abstract
 

Sarah Herberger, Nadine Oberkircher, Gentiana I. Wenzel, Dietmar Hecker, Gudrun Wagenpfeil, Rhoikos Furtwängler, Sören L. Becker, Cihan Papan, Norbert Graf, Arne Simon 

Prospektives Audit des Gentamicin Drug Monitorings in einem Kinderkrebszentrum

Klin Pädiatr 2021; doi: 10.1055/a-1352-50 -> Abstract
 

Simon A, Lein-Köhler I, Metz B, Gärtner B, Rissland J, Graf N

Management einer COVID-19-Pandemie in einer kinderonkologischen Klinik

HygMed 46(1-2):D16-D22, 2021
 

Karsten Theiß, Arne Simon, Norbert Graf, Tilman Rohrer

Auswirkungen des Lockdownsvwährend der ersten COVID-19-Welle auf 34 kinder- und jugendärztliche Praxen im Saarland 

Monatsschr Kinderheilkd 2021; doi: 10.1007/s00112-021-01125-9 -> Abstract
 

Martin Häusler, Hans Martin Bosse, Thomas Fischbach, Norbert Graf, Jürgen-Christoph von Kleist-Retzow, Joachim Kreuder

Alice im digitalen Wunderland: pädiatrische Lehre in der COVID-19-Pandemie

Monatsschr Kinderheilkd 169:151–158, 2021; doi: 10.1007/s00112-020-01076-7 -> Abstract
 

Hol, J, Jongmans MCJ, Sudour-Bonnange H, Ramirez-Villar L, Chowdhury T, Rechnitzer C, Pal N, Schleiermacher G, Karow A, Kuiper R, de Camargo B, Avcin S, Redzic D, Wachtel A, Segers H, Vujanic GM, van Tinteren H, Bergeron C, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM on behalf of the International Society of Pediatric Oncology-Renal Tumor Study Group (SIOP-RTSG)

Clinical characteristics and outcome of children with WAGR syndrome and Wilms tumor and/or nephroblastomatosis: 30-year SIOP-RTSG experience

Cancer 127:628-638, 2021; doi: 10.1002/cncr.33304 -> Abstract
 

van der Beek JN, Hol JA, Coulomb-l’HermineA, GrafN, Van TinterenH, Pritchard-JonesK, Houwing ME, de Krijger RR, VujanicGM, DzhumaK, Schenk JP, Littooij AS, Ramírez-Villar GL, Murphy D, Ray S, Al-Saadi R, Gessler M, Godzinski J, Ruebe C, Collini P, Verschuur AC, Frisk T, Vokuhl C, Hulsbergen-van de Kaa CA, De Camargo B, Sandstedt B, Selle B, Tytgat GAM, van den Heuvel-Eibrink MM 

Characteristics and outcome of Pediatric Renal Cell Carcinoma patients registered in the International Society of Pediatric Oncology (SIOP) 93-01, 2001, and UK-IMPORT database: A report of the SIOP-Renal Tumor Study Group

Int J Cancer 2021; DOI:10.1002/ijc.33476 ->Abstract
 

Waltraud Friesenbichler, Rowitha Lüftinger, Gabriele Kropshofer, Martin Henkel, Gabriele Amann, Rhoikos Furtwängler, Norbert Graf, Leo Kager

Clear cell sarcoma of the kidney in Austrian children: Long‐term survival after relapse

Ped Blood & Cancer 2021; DOI:10.1002/pbc.28860 ->Abstract
 

Marie V. Nelson, Marry M. van den Heuvel-Eibrink, Norbert Graf, Jeffrey S. Dome

New approaches to risk stratification for Wilms tumor

Curr Opin Pediatr 2021, 32:000–000; DOI:10.1097/MOP.0000000000000988 ->Abstract
 

Jesper Brok, Annelies MC Mavinkurve-Groothuis, Jarno Drost, Daniela Perotti, James I Geller, Amy L Walz, Birgit Geoerger, Claudia Pasqualini, Arnauld Verschuur, Angela Polanco, Kathy Pritchard Jones, Marry van den Heuvel-Eibrink,Norbert Graf, Filippo Spreafico

Unmet needs for relapsed or refractory Wilms tumour: mapping the molecular features, exploring organoids and designing early phase trials. a collaborative SIOP-RTSG, COG, & ITCC session at the 1st SIOPE meeting

Eur J Cancer 144:113-122, 2021; DOI: 10.1016/j.ejca.2020.11.012 ->Abstract
 

Heike von Baum, Peter Bischoff, Maximilian Christopeit, Steffen Engelhart, Martin Exner, Thomas Lehrnbecher, Arne Simon (Leiter der Arbeitsgruppe), Eva Feuerhahn, Melanie Brunke (Robert Koch-Institut); (Empfehlungen der Kommission für Krankenhaushygiene und Infektionsprävention (KRINKO) beim Robert Koch-Institut)

Anforderungen an die Infektionsprävention bei der medizinischen Versorgung von immunsupprimierten Patienten

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 53(4):357-388, 2021; https:// doi.org/10.1007/ s00103- 020- 03265 -> Abstract
 

Walger P, Knuf M, Hübner J, Exner M, Zahn D, Zahn T, Huppertz HI, Elvermann K, Simon A

Hygienische Aspekte zum Umgang mit der SARS-CoV-2-Pandemie in Einrichtungen mit mehrdimensionalen, sonderpädagogischen Fördermöglichkeiten

Hygiene & Medizin 46:1-2, 2021 -> Abstract
 

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2020

Walger P, Knuf M, Hübner J, Exner M, Zahn D, Zahn T, Huppertz HI, Elvermann K, Simon A

Hygienische Aspekte zum Umgang mit der SARS-CoV-2-Pandemie in Einrichtungen mit mehrdimensionalen, sonderpädagogischen Fördermöglichkeiten

Hygiene & Medizin 46:1-2, 2021 -> Abstract

Müller S, Weickert J, Graf N

Robustness of Brain Tumor Segmentation

J Medical Imaging 7(6):1-18, 2020 -> Abstract

Kunz JB, Lobitz S, Grosse R, Oevermann L, Hakimeh D, Jarisch A, Cario H, Beier R, Schenk D, Schneider D, Groß-Wieltsch U, Prokop A, Heine S, Khurana C, Erlacher M, Dürken M, Linke C, Frühwald M, Corbacioglu S, Claviez A, Metzler M, Ebinger M, Full H, Wiesel T, Eberl W, Reinhard H, Tagliaferri L, Allard P, Karapanagiotou-Schenkel I, Rother LM, Beck D, Le Cornet L, Kulozik AE; German Sickle Cell Disease Registry

Sickle cell disease in Germany: Results from a national registry

Pediatr Blood Cancer 67(4):e28130, 2020; doi: 10.1002/pbc.28130   -> Abstract

Katharina Sauter, Leonie Egle, Svenja Ockfen, Manfred Haber, Sören L Becker, Gudrun Wagenpfeil, Norbert Graf, Arne Simon

Systemic Antifungal use in a Pediatric Cancer Center - Audit Comparing Pharmacy Dispensing Data with Patient - Derived Consumption

Ann Pediatr 3(1): 1045, 2020 -> Abstract

Nemes K, Bens S, Kachanov D, Teleshova M, Hauser P, Simon T, Tippelt S, Woessmann W, Beck O, Flotho C, Grigull L, Driever PH, Schlegel PG, Khurana C, Hering K, Kolb R, Leipold A, Abbink F, Gil-Da-Costa MJ, Benesch M, Kerl K, Lowis S, Marques CH, Graf N, Nysom K, Vokuhl C, Melchior P, Kröncke T, Schneppenheim R, Kordes U, Gerss J, Siebert R, Furtwängler R, Frühwald MC

Clinical and genetic risk factors define two risk groups of extracranial malignant rhabdoid tumours (eMRT/RTK)

Eur J Cancer 142:112-122, 2020; doi: 10.1016/j.ejca.2020.10.004 -> Abstract

Martin Häusler, HansMartin Bosse, Thomas Fischbach, Norbert Graf, Jürgen-Christoph von Kleist-Retzow, Joachim Kreuder

Alice im digitalen Wunderland: pädiatrische Lehre in der COVID-19-Pandemie

Monatsschr Kinderheilkd 2020; doi: 10.1007/s00112-020-01076-7 -> Abstract

Reinhard Berner, Johannes Huebner, Hans-Iko Huppertz, Arne Simon, Peter Walger

Kinder mit akuter Atemwegsinfektion in Kinderkliniken im Herbst/Winter 2020/21 - Empfehlungen der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI) und der Deutschen Gesellschaft für Krankenhaushygiene (DGKH) (Stand 14.10.2020)

Monatsschr Kinderheilkd, 2020; doi: 10.1007/s00112-020-01058-9 -> Abstract

Janssens GO, Melchior P, Mul J, Saunders D, Bolle S, Cameron AL, Claude L, Gurtner K, van de Ven, KP, van Grotel M, Harrabi S, Lassen-Ramshad Y, Lavan N, Magelssen H, Muracciole X, Boterberg T, Mandeville H, Godzinski J, Graf N, van den Heuvel-Eibrink M, Ruebe C

The SIOP-Renal Tumour Study Group consensus on flank target delineation for highly conformal radiotherapy

Lancet Child & Adolescent Health 4(11):846-852, 2020; doi: 10.1016/S2352-4642(20)30183-8 -> Abstract

Härtel C, Faust K, Fortmann I, Humberg A, Pagel J, Haug C, Kühl R, Bohnhorst B, Pirr S, Viemann D, Simon A, Zemlin M, Poralla S, Müller A, Köstlin-Gille N, Gille C, Heckmann M, Rupp J, Herting E, Göpel W

Sepsis related mortality of extremely low gestational age newborns after the introduction of colonization screening for multi-drug resistant organisms

Antimicrob Resist Infect Control 26;9(1):144. 2020, doi: 10.1186/s13756-020-00804-8 -> Abstract

Arne Simon, Johannes Huebner, Reinhard Berner, Alasdair P.S. Munro, Martin Exner, Hans-Iko Huppertz, Peter Walger

Measures to maintain regular operations and prevent outbreaks of SARS-CoV-2 in childcare facilities or schools under pandemic conditions and co-circulation of other respiratory pathogens

GMS Hygiene and Infection Control 15:1-12, 2020; doi: 10.3205/dgkh000357 -> Abstract

Kutscher LM, Okonechnikov K, Batora NV, Clark J, Silva PBG, Vouri M, van Rijn S, Sieber L, Statz B, Gearhart MD, Shiraishi R, Mack N, Orr BA, Korshunov A, Gudenas BL, Smith KS, Mercier AL, Ayrault O, Hoshino M, Kool M, von Hoff K, Graf N, Fleishhack G, Bardwell VJ, Pfister SM, Northcott PA, Kawauchi D

Functional loss of a noncanonical BCOR–PRC1.1 complex accelerates SHH-driven medulloblastoma formation.

Genes & Development 34:1–16, 2020; doi:10.1101/gad.337584.120 -> Abstract

Justine N. van der Beek , James I. Geller, Ronald R. de Krijger, Norbert Graf, Kathy Pritchard-Jones, Jarno Drost, Arnauld C. Verschuur, Dermot Murphy, Satyajit Ray, Filippo Spreafico, Kristina Dzhuma, Annemieke S. Littooij, Barbara Selle, Godelieve A.M. Tytgat, Marry M. van den Heuvel-Eibrink

Characteristics and outcome of children with Renal Cell Carcinoma: A Narrative review.

Cancers, 2020, 12, 1776; doi:10.3390/cancers12071776 -> Abstract

Nasenien Nourkami-Tutdibi, Arne Simon, Rhoikos Furtwängler, Norbert Graf, Umut Yilmaz, Joachim Oertel, Sascha Meyer

Persistent aseptic meningitis in a child—think patch.

Wien Med Wochenschr; doi: 10.1007/s10354-020-00765-y -> Abstract

Holstein K, Albisetti M, Bidlingmaier C, Halimeh S, Sabine Heine, Klamroth R, Königs C, Kurnik K, Male C, Oldenburg J, Streif W, Wermes C, Escuriola-Ettingshausen C, ‘Ständige Kommission Hämophilie’ (Haemophilia board) of the German, Swiss Austrian Society for Thrombosis Haemostasis Research (GTH)

Practical Guidance of the GTH Haemophilia Board on the Use of Emicizumab in Patients with Haemophilia A.

Hämostaseologie, 2020; doi: 10.1055/a-1127-6476 -> Abstract

Max Scheler, Thomas Lehrnbecher, Andreas H. Groll, Ruth Volland, Hans-Jürgen Laws, Roland A. Ammann5, Philipp Agyeman, Andishe Attarbaschi, Margaux Lux, Arne Simon

Management of children with fever and neutropenia: results of a survey in 51 pediatric cancer centers in Germany, Austria, and Switzerland.

Infection, 2020; doi: 10.1007/s15010-020-01462-z -> Abstract

Arne Simon, Johannes Hübner, Markus Knuf, Markus Hufnagel, Reinhard Berner

Management of Care for Neonates Born to SARS-CoV-2 Positive Women with or without Clinical Symptoms (COVID-19)

Klin Pädiatrie 2020; doi:10.1055/a-1168-2845 -> Abstract

Christa Koenig, Nicole Bodmer, Philipp K A Agyeman, Felix Niggli, Cécile Adam, Marc Ansari, Bernhard Eisenreich, Nanette Keller, Kurt Leibundgut, David Nadal, Jochen Roessler, Katrin Scheinemann, Arne Simon, Oliver Teuffel, Nicolas X von der Weid, Michael Zeller, Karin Zimmermann, Roland A Ammann

39·0°C versus 38·5°C ear temperature as fever limit in children with neutropenia undergoing chemotherapy for cancer: a multicentre, cluster-randomised, multiple-crossover, non-inferiority trial.

Lancet Child Adolesc Health 2020; doi:10.1016/S2352-4642(20)30092-4 -> Abstract

Christian Siebel, Gudrun Würthwein, Claudia Lanvers-Kaminsk, Nicolas André, Frank Berthold, Ilaria Castelli, Pascal Chastagner, François Doz, Martin English, Gabriele Escherich, Michael C. Frühwald, Norbert Graf, Andreas Groll, Antonio Ruggiero, Georg Hempel, Joachim Boos

Can We Optimise Doxorubicin Treatment Regimens for Children with Cancer? Pharmacokinetic Simulations and a Delphi Consensus Procedure.

BMC Pharmacology and Toxicology 2020 21:3; DOI: 10.1186/s40360-020-00417-2 -> Abstract

Peter Walger, Ulrich Heininger, Markus Knuf, Martin Exner, Walter Popp, Thomas Fischbach, Stefan Trapp, Johannes Hübner, Caroline Herr, Arne Simon

Children and adolescents in the CoVid-19 pandemic: Schools and daycare centers are to be opened again without restrictions. The protection of teachers, educators, carers and parents and the general hygiene rules do not conflict with this.

GMS Hyg Infect Control. 2020;15:Doc1; DOI:10.3205/dgkh000346 -> Abstract

Janina Marissen, Ingmar Fortmann, Alexander Humberg, Tanja K. Rausch, Arne Simon, Anja Stein, Thomas Schaible, Joachim Eichhorn, Jürgen Wintgens, Claudia Roll, Friedhelm Heitmann, Egbert Herting, Wolfgang Göpel, Christoph Härtel on behalf of the German Neonatal Network

Vancomycin-induced ototoxicity in very-low-birthweight infants.

J Antimicrob Chemother 2020; doi:10.1093/jac/dkaa156 -> Abstract

Patrick Melchior, Yvonne Dzierma, Christian Rübe, Norbert Graf, Leo Kager, Sabine Kroiss, Jochen Hubertus, Steven Warmann, Jens-Peter Schenk, Ivo Leuschner, Karolina Nemes, Clemens Magnus Meier, Christian Vokuhl, Michael C. Frühwald, Rhoikos Furtwängler

Local Stage dependent necessity of Radiotherapy in Rhabdoid Tumors of the Kidney (RTK) – the GPOH experience.

International Journal of Radiation Oncology, Biology, Physics, 2020; doi:10.1016/j.ijrobp.2020.04.046 -> Abstract

Jakob Peter Armann, Natalie Diffloth, Arne Simon, Maren Doenhardt, Markus Hufnagel, Andreas Trotter, Dominik Schneider, Johannes Hübner, Reinhard Berner

Hospital admission in children and adolescents with COVID-19—early results from a national survey conducted by the German Society for Pediatric Infectious Diseases (DGPI).

Deutsches Ärzteblatt 117 (21):373-374, 2020; doi:10.3238/arztebl.2020.0373 -> Abstract

Sylvia von Mackensen, Christian Schleicher, Sabine Heine, Norbert Graf, Hermann Eichler

Health-Related Quality of Life, Treatment Satisfaction and Adherence Outcomes of Haemophilia Patients Living in a German Rural Region.

Hämostaseologie 2020; doi:10.1055/a-1141-1175 -> Abstract

Hans-Jürgen Laws, Ulrich Baumann, Christian Bogdan, Gerd Burchard, Maximilian Christopeit, Jane Hecht, Ulrich Heininger, Inken Hilgendorf, Winfried Kern, Kerstin Kling, Guido Kobbe, Wiebe Külper, Thomas Lehrnbecher, Roland Meisel, Arne Simon, Andrew Ullmann, Maike de Wit, Fred Zepp

Impfen bei Immundefizienz. Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen. (III) Impfen bei hämatologischen und onkologischen Erkrankungen (antineoplastische Therapie, Stammzelltransplantation), Organtransplantation und Asplenie.

Gesundheitsschutz 63:588-644, 2020; doi:10.1007/s00103-020-03123-w -> Abstract

Michael Sullivan, Eric Bouffet, Carlos Rodriguez-Galindo, Sandra Luna-Fineman, Muhammad Saghir Khan, Pam Kearns, Douglas S. Hawkins, Julia Challinor, Lisa Morrissey, Jörg Fuchs, Karen Marcus, Adriana Balduzzi, Luisa Basset-Salom, Miguela Caniza, Justin N. Baker, Rejin Kebudi, Laila Hessissen, Richard Sullivan, Kathy Pritchard-Jones

The COVID-19 PANDEMIC: A Rapid Global response for Children with Cancer from SIOP, COG, SIOP-E, SIOP-PODC, IPSO, PROS, CCI and St Jude Global.

Suppl1(5): Norbert Graf, Conrad Fernandez C with input from Filippo Spreafico, Marry van den Heuvel, Kathy Pritchard-Jones, Trijn Israels: Wilms Tumour (Nephroblastoma): Guidance on how to adapt diagnostic work-up and treatment protocols during COVID-19 pandemic.

Ped Blood & Cancer 2020; doi:10.22541/au.158777298.87289192 -> Abstract

Gessler M, Graf N

Less may be more for stage I epithelial Wilms tumor (Editorial).

Cancer 2020; doi:10.1002/cncr.32854 -> Abstract

Moatasem Elayadi, Mahmoud Hammad, Kareem Sallam, Gehad Ahmed, Soha Ahmed, Ahmed Ibrahim, Amal Refaat, Naglaa Elkinaai, Alaa Younes, Norbert Graf, Wael Zekri

Management and outcome of pediatric Wilms tumor with malignant inferior Vena cava thrombus: largest cohort of single-center experience.

Int J Clin Oncol 2020; doi:10.1007/s1014 7-020-01667 -0 -> Abstract

Nourkami-Tutdibi N, Graf N, Beier R, Zemlin M, Tutdibi E

Plasma levels of osteopontin from birth to adulthood.

Ped Blood & Cancer 2020;e28272 doi:110.1002/pbc.28272 -> Abstract

Ariadne H.A.G. Ooms, Gordan M. Vujanić, Ellen D’Hooghe, Paola Collini, Aurore L’Herminé-Coulomb, Christian Vokuhl, Norbert Graf, Marry M. van den Heuvel-Eibrink, Ronald R. de Krijger

Renal Tumors of Childhood—A Histopathologic Pattern-Based Diagnostic Approach.

Cancers 12, 729, 2020 doi:10.3390/cancers12030729 -> Abstract

Pia Schmidt, Carola Hasan, Arne Simon, Christine Geffers, Julia Wager, Boris Zernikow

Multidrug-resistant bacteria in a paediatric palliative care inpatient unit: results of a one year surveillance.

GMS Hygiene and Infection Control 15: 1-9, 2020; ISSN 2196-5226 -> Abstract

Andreas M. Hötker, André Lollert, Yousef Mazaheri, Sabine Müller, Jens- Peter Schenk, Philipp Mildenberger, Oguz Akin, Norbert Graf, Gundula Staatz

Diffusion-weighted MRI in the Assessment of Nephroblastoma: Results of a Multi-Center Trial

Abdominal Radiology, 2020, doi:10.1007/s00261-020-02475-w -> Abstract

Ann-Kathrin Desch, Kristin Hartung, Ante Boten, Alexander Brobeil, Mathias Rummel,  Lars Kurch, Thomas Georgi, Theresa Jox, Stefan Bielack, Stefan Burdach, Carl Friedrich Classen, Alexander Claviez, Klaus-Michael Debatin, Martin Ebinger, Angelika Eggert, Jörg Faber,Christian Flotho,Michael Frühwald, Norbert Graf, Norbert Jorch, Udo Kontny, Christof Kramm, Andreas Kulozik, Joachim Kühr, Karl-Walter Sykora, Markus Metzler, Hermann L. Müller, Michaela Nathrath, Thomas Nüßlein, Michael Paulussen, Arnulf Pekrun, Dirk Reinhardt, Harald Reinhard, Claudia Rössig, Axel Sauerbrey, Paul-Gerhardt Schlegel, Dominik T. Schneider, Wolfram Scheurlen, Lothar Schweigerer, Thorsten Simon, Meinolf Suttorp, Peter Vorwerk, Roland Schmitz, Regine Kluge,Christine Mauz-Körholz, Dieter Körholz, Stefan Gattenlöhner, Andreas Bräuninger

Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma

Leukemia 34:151-166, 2020, doi:10.1038/s41375-019-0541-6 -> Abstract

Pasqualini C, Furtwängler R, van Tinteren H, Teixera RAP, Acha T, Howell L, Vujanic G, Godzinski J, Melchior P, Smets A, Coulomb-L’Hermine A, Brisse H, Pritchard-Jones K, Bergeron C, de Camargo B, van den Heuvel-Eibrink MM, Graf N, Verschuur AC

Outcome of patients with stage IV high-risk Wilms tumour treated according to the SIOP2001 protocol: a report of the SIOP Renal Tumour Study Group

Eur J Cancer, 128:38-46, 2020, doi:10.1016/j.ejca.2020.01.001 -> Abstract

Michael C. Frühwald, Martin Hasselblatt, Karolina Nemes, Susanne Bens, Mona Steinbügl, Pascal D Johann, Kornelius Kerl, Peter Hauser, Eduardo Quiroga, Palma Solano-Paez, Veronica Biassoni, Maria Joao Gil-da-Costa, Martha Perek-Polnik, Marianne van de Wetering, David Sumerauer, Jane Pears, Niklas Stabell, Stefan Holm, Heinz Hengartner, Nicolas U. Gerber, Michael Grotzer, Joachim Boos, Martin Ebinger, Stefan Tippelt, Werner Paulus, Rhoikos Furtwängler, Pablo Hernáiz-Driever, Harald Reinhard, Stefan Rutkowski, Paul-Gerhardt Schlegel, Irene Schmid, Rolf-Dieter Kortmann, Beate Timmermann, Monika Warmuth-Metz, Uwe Kordes, Joachim Gerss , Karsten Nysom, Reinhard Schneppenheim, Reiner Siebert, Marcel Kool, and Norbert Graf

Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors

Neuro-Oncology, doi:10.1093/neuonc/noz244 -> Abstract

Becker C, Graf N, Grabow D, Creutzig U, Reinhardt D, Weyer-Elberich V, Spix C, Kaatsch P

Early deaths from childhood cancer in Germany 1980-2016

Cancer Epidemiology 65 (2020) doi: 10.1669/j.canep.2020.101669-> Abstract

Müller S, Weickert J, Graf N

Wilms’ Tumor in Childhood: Can Pattern Recognition Help for Classification?

In: Zheng Y., Williams B., Chen K. (eds) Medical Image Understanding and Analysis. MIUA 2019. Communications in Computer and Information Science, vol 1065. Springer, Cham, 2020; doi: 10.1007/978-3-030-39343-4_4 -> Abstract

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2019

Hol JA, Lopez-Yurda MI, Van Tinteren H, Van Grotel M¹, Godzinski J, Vujanic G, Oldenburger F, De Camargo B, Ramirez G, Bergeron C, Pritchard-Jones K, Graf N, Van den Heuvel-Eibrink MM

Prognostic significance of age in 5631 patients with Wilms tumor prospectively registered in International Society of Pediatric Oncology (SIOP) 93-01 and SIOP 2001

PLOS ONE 14(8): e0221373 2019; doi: 10.1371/journal.pone.0221373 -> Abstract

Christos Maramis, Christina Karamanidou, Fatima Schera, Stephan Kiefer, Lefteris Koumakis, Konstantinos Marias, Stefan Hoffmann, Heather Parker, Jonathan Reston, Sheila Payne, Sarka Pospisilova, Richard Rosenquist, Paolo Ghia, Charalampos Pontikoglou, Annette Sander, Michael Doubek, Norbert Graf, Julie Ling, Julia Downing, Elpida Pavi and Vassilis Koutkias

Using Electronic Patient Reported Outcomes to Foster Palliative Cancer Care: the MyPal Approach

Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019, 10 2019 -> Abstract

Müller S, Weickert J, Graf N

Robustness of Brain Tumor Segmentation

arXiv preprint arXiv:1912.11312, 2019 -> Abstract

Kondylakis H, Bucur A, Crico C, Dong F, Graf N, Hoffmann S, Koumakis L, Manenti A, Marias K, Mazzocco K, Pravettoni G, Renzi C, Schera F, Triberti S, Tsiknakis M, Kiefer S

Patient empowerment for cancer patients throiugh a novel ICT infrastructure

J Biomedical Informatics 101 (2020) 103342; doi: 10.1016/j.jbi.2019.103342 -> Abstract

Meyer S, Nüßlein T, Nährlich L, Bend J, Gärtner B, Becker SL, Simon A

Infection prevention and control in patients with cystic fibrosis (CF): Results from a survey in 35 German CF treatment cenbters

J Cyst Fibros pii: S1569-1993(19)30925-7, 2019; doi: 10.1016/j.jcf.2019.10.012-> Abstract

Tsiknakis M, Graf N, Stamatopoulos K, Bucur A

Guest Editorial: Biomedical Informatics Across the Cancer Continuum

IEEE Journal of Biomedical and Health Informatics 23(5):1819-1820, 2019; doi: 10.1109/JBHI.2019.2932279 -> Abstract

Fajardo RD, van den Heuvel-Eibrink MM, Spreafico F, van Tinteren H, Acha T, Bergeron C, de Camargo B, Oldenburger F, Rübe C, Oue T, Leuschner I, Vujanic G, Sebire N, Coulomb-L’Hermine A, Collini P, Pritchard-Jones K, Graf N, Janssens GO, van Grotel M
Is radiotherapy required in first‐line treatment of stage I diffuse anaplastic Wilms tumor? A report of SIOP‐RTSG, AIEOP, JWiTS, and UKCCSG
Pediatr Blood Cancer e28039, 2019; doi: 10.1002/pbc.28039 ->Abstract

Wegert J, Zauter L, Appenzeller S, Otto C, Bausenwein S, Vokuhl C, Ernestus K, Furtwängler R, Graf N, Gessler M
High-risk balstemal Wilms tumor can be modelled by 3D spheroid cultures in vitro.
Oncogene, 2019; doi: 10.1038/s41388-019-1027-8 ->Abstract

Filippo Spreafico, Arnaud Dalissier, Ulrike Pötschger, Franco Locatelli, Jean Michon, Christina Peters, Peter Bader, Gianni Bisogno, Daniel Yeomanason, Andre Willasch, Marry van den Heuvel Eibrink, Graf N, Sandro Dallorso

High dose chemotherapy and autologous hematopoietic cell transplantation for Wilms tumor: A study of the European society for Blood and Marrow Transplantation

Nature Bone Marrow Transplantation 2019; doi: 10.1038/s41409-019-0661-7 -> Abstract

Ann-Kathrin Desch, Kristin Hartung, Ante Botzen, Alexander Brobeil, Mathias Rummel, Lars Kurch, Thomas Georgi, Theresa Jox, Stefan Burdach, Carl Friedrich Classen, Alexander Claviez, Klaus-Michael Debatin, Angelika Eggert, Jörg Faber, Christian Flotho, Michael Frühwald, Graf N, Rupert Handgretinger, André Hofmann, Norbert Jorch, Stephanie Knirsch, Udo Kontny, Christof Kramm, Andreas Kulozik, Joachim Kühr, Britta Maecker-Kolhoff, Markus Metzler, Hermann L. Müller, Michaela Nathrath, Thomas Nüßlein, Michael Paulussen, Arnulf Pekrun, Dirk Reinhardt, Harald Reinhard, Claudia Rössig, Axel Sauerbrey, Paul-Gerhardt Schlegel, Dominik T. Schneider, Wolfram Scheurlen, Lothar Schweigerer, Thorsten Simon, Meinolf Suttorp, Peter Vorwerk, Regine Kluge, Christine Mauz-Körholz, Dieter Körholz, Stefan Gattenlöhner, Andreas Bräuninger

Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma to determine pathogenic mechanisms and monitor therapy

Leukemia. 2019, doi: 10.1038/s41375-019-0541-6 --> Abstract

Kaba D, McFarlane N, Dong F, Graf N, Xujiong Ye

Nephroblastoma analysis in MRI images

Image Anal Stereol 38:173-183, 2019 doi:10.5566/ias.2000 -> Abstract

Müller S, Farag I, Weickert J, Braun Y, Lollert A, Dobberstein J, Hötker A, Graf N

Benchmarking Wilms’ tumor in multisequence MRI data: why does current clinical practice fail? Which popular segmentation algorithms perform well?

Medical Imaging 6(3), 034001, 2019; doi: 10.1117/1.JMI.6.3.034001 -> Abstract

Sabine M. El-Helou, Anika-Kerstin Biegner, Sebastian Bode, Stephan R Ehl, Maximilian Heeg, Maria Elena Maccari, Henrike Ritterbusch, Stephan Rusch, Raphael Scheible, Klaus Warnatz, Faranaz Atschekzei, Renata Beider, Diana Ernst, Stev Gerschmann, Alexandra Jablonka, Gudrun Mielke, Reinhold Ernst Schmidt, Gesine Schürmann, Georgios Sogkas, Ulrich Hermann Baumann, Christian Klemann, Dorothee Viemann, Horst von Bernuth, Renate Krüger, Leif G. Hanitsch, Carmen Scheibenbogen, Kirsten Wittke, Michael H. Albert, Anna Eichinger, Fabian Hauck, Christoph Klein, Anita Rack-Hoch, Franz Michael Sollinger, Anne Avila, Michael Borte, Stephan Borte, Maria Fasshauer, Anja Hauenherm, Nils Kellner, Anna Hedwig Müller, Anett Ülzen, Peter Bader, Shahrzad Bakhtiar, Jae-Yun Lee, Ursula Heß, Ralf Schubert, Sandra Woelke, Zielen Stefan, Sujal Ghosh, Hans-Juergen Laws, Jennifer Neubert, Prasad Thomas Oommen, Manfred Hoenig, Ansgar S Schulz, Sandra Steinmann, Klaus Schwarz, Gregor Dückers, Beate Lamers, Vanessa Langemeyer, Tim Niehues, Sonu Shai, Dagmar Graf, Carmen Müglich, Marc Thomas Schmalzing, Eva Christina Schwaneck, Hans-Peter Tony, Gabriele Haase, Johannes Günter Liese, Henner Morbach, Florian Segerer, Dirk Foell, Antje Hellige, Helmut Wittkowski, Katja Masjosthusmann, Michael Mohr, Linda Geberzahn, Christian Michael Hedrich, Christiane Müller, Angela Rösen-Wolff, Joachim Roesler, Antje Zimmermann, Uta Behrends, Nikolaus Rieber, Uwe Schauer, Rupert Handgtretinger, Ursula Holzer, Jörg Henes, Lothar Kanz, Christoph Boesecke, Jürgen K. Rockstroh, Carolynne Schwarze-Zander, Jan-Christian Wasmuth, Dagmar Dilloo, Brigitte Hülsmann, Stefan Schönberger, Stefan Schreiber, Rainald Zeuner, Tobias Ankermann, Philipp von Bismarck, Hans-Iko Huppertz, Petra Kaiser-Labusch, Johann Greil, Donate Jakoby, Andreas E. Kulozik, Markus Metzler, Nora Naumann-Bartsch, Bettina Sobik, Graf N, Sabine Heine, Robin Kobbe, Kai Lehmberg, Ingo Müller, Friedrich Herrmann, Gerd Horneff, Ariane Klein, Joachim Peitz, Nadine Schmidt, Stefan Bielack, Ute Groß-Wieltsch, Carl Friedrich Classen, Jessica Klasen, Peter Deutz, Dirk Kamitz, Lisa Lassay, Klaus Tenbrock, Norbert Wagner, Benedikt Bernbeck, Bastian Brummel, Eusebia Lara-Villacanas, Esther Münstermann, Dominik T. Schneider, Nadine Tietsch, Marco Westkemper, Michael Weiß, Christof Kramm, Ingrid Kühnle, Silke Kullmann, Hermann Girschick, Christof Specker, Elisabeth Vinnemeier-Laubenthal, Henriette Haenicke, Claudia Schulz, Lothar Schweigerer, Thomas Gerd Müller, Martina Stiefel, Bernd H. Belohradsky, Veronika Soetedjo, Gerhard Kindle, Bodo Grimbacher

The German National Registry of Primary Immunodeficiencies

Frontiers in Immunology 10, Article 1272:1-25, 2019; doi: 10.3389/fimmu.2019.01272 -> Abstract

Irtan S, Van Tinteren H, Graf N, van den Heuvel-Eibrink M, Heij H, Bergeron Ch, de Camargo B, Acha T,  Spreafico F, Vujanic G,Powis M, Okoye B, Wilde J, Godzinski J,  Pritchard-Jones K

Evaluation of needle biopsy as a potential risk factor for local recurrence of Wilms Tumour in the SIOP WT 2001 trial

Eur J Cancer 116:13-20, 2019, doi: 10.1016/j.ejca.2019.04.027 -> Abstract

Schneider L, Kehl T, Thedinga K, Grammes NL, Backes C, Mohr C, Schubert B, Lenhof K, Gerstner N, Hartkopf AD, Wallwiener M, Kohlbacher O, Keller A, Meese E, Graf N, Lenhof HP

ClinOmicsTrail: a visual analytics tool for breast cancer treatment stratification

Bioinformatics 1-11, 2019, doi: 10.1093/bioinformatics/btz302-> Abstract

Fleischhack G, Massimino M, Warmuth-Metz M, Khuhlaeva E, Janssen G, Graf N, Rutkowski S, Beilken A, Schmid I, Biassoni V, Gorelishev SK, Kramm C, Reinhard H, Schlegel PG, Kortmann RD, Reuter D, Bach F, Iznaga-Escobar NE, Bode U

Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study

Journal of Neuro-Oncology 143:107–113, 2019, doi: 10.1007/s11060-019-03140-z -> Abstract

Anticancer Research 39(4);2043-2051, 2019, doi:10.21873/anticanres.13315. [Epub ahead of print] -> Abstract

Shazia Mahamdallie, Shawn Yost, Emma Poyastro-Pearson, Esty Holt, Anna Zachariou, Sheila Seal, Anna Elliott, Matthew Clarke, Margaret Warren-Perry, Sandra Hanks, John Anderson, Simon Bomken, Trevor Cole, Roula Farah, Rhoikos Furtwaengler, Adam Glaser, Richard Grundy, James Hayden, Steve Lowis, Frédéric Millot, James Nicholson, Milind Ronghe, Jane Skeen, Denise Williams, Daniel Yeomanson, Elise Ruark, Nazneen Rahman

Identification of new Wilms tumour predisposition genes: an exome sequencing study

Lancet Child Adolesc Health, 2019, doi: 10.1016/S2352-4642(19)30018-5. [Epub ahead of print] -> Abstract

Illja J. Diets, Juliane Hoyer, Arif B Ekici, Bernt Popp, Nicoline Hoogerbrugge, Simon van Reijmersdal, Rajith Bhaskaran,Michel Hadjihannas, Georgia Vasileiou, Christian T. Thiel, Didem Seven, Steffen Uebe, Denisa Ilencikova, Esmé Waanders, Annelies MC Mavinkurve, Nel Roeleveld, Ronald de Krijger, Jenny Wegert, Norbert Graf, Christian Vokuhl, Abbas Agaimy, Manfred Gessler, André Reis, Roland P. Kuiper, Marjolijn C. Jongmans, Markus Metzler

TRIM28 haploinsufficiency predisposes to Wilms tumor.

Int J Cancer, 2019, doi: 10.1002/ijc.32167. [Epub ahead of print] -> Abstract

Tim Kehl, Lara Schneider, Kathrin Kattler, Daniel Stöckel, Jenny Wegert, Nico Gerstner, Nicole Ludwig, Ute Distler, Stefan Tenzer, Manfred Gessler, Jörn Walter, Andreas Keller, Norbert Graf, Eckart Meese, Hans-Peter Lenhof

The role of TCF3 as potential master regulation in blastemal Wilms Tumors

Int J Cancer 144:1432-1443, 2019; doi: 10.1002/ijc.31834 -> Abstract

B. Seitz, N. Graf, M. Menger, D.Monz, B.Käsmann-Kellner

Etablierung einer PJ-Faculty an der Medizinischen Fakultät der Universität des Saarlandes UdS - „Docendo discimus“, „Transparenz und Kommunikation“

Ophthalmologe 116:28-32, 2019; doi: 10.1007/s00347-018-0821-y -> Abstract

Nasenien Nourkami-Tutdibi, Arne Simon, Peter Fries, Sören L Becker, Petra Ecker, Michael Zemlin, Sascha Meyer

A 5-year-old boy with a chronic cough caused by Echinococcus granulosus

The Lancet 393, 10166: 74, 2019, doi: 10.1016/S0140-6736(18)32852-6 -> Abstract

Hans-Jürgen Laws, Arne Simon, Thomas Lehrnbecher

Revaccination in Children Undergoing Autologous Hematopoietic Stem Cell Transplantation: Results of a Survey in Germany, Austria and Switzerland

Klin Pädiatr 2019, doi: 10.1055/a-0796-6719, PIMD:30602176 -> Abstract

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2018

Vujanic G, Gessler M, Ooms A, Collini P, Coulomb-l’Hermine A, D'Hooghe E, de Krijger R, Perotti D, Pritchard-Jones K, Vokuhl C, van den Heuvel-Eibrink M, Graf N

Position Paper: The UMBRELLA SIOP-RTSG 2016 study pathology and molecular biology protocol

Nature Reviews Urology 2018 Nov;15(11):693-701. doi: 10.1038/s41585-018-0100-3 -> Abstract

Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP
The role of TCF3 as potential master regulator in blastemal Wilms tumors
Int J Cancer. 2018 Aug 28. doi: 10.1002/ijc.31834 -> Abstract

Friesenbichler W, Krizmanich W, Lakatos K, Attarbaschi A, Dworzak M, Amann G, Furtwängler R, Graf N, Kager L
Outcome of two patients with bilateral nephroblastomatosis/Wilms tumour treated with an add-on 13-cis retinoic acid therapy - Case report.
Pediatr Hematol Oncol. 2018 Sep 27:1-7. doi: 10.1080/08880018.2018.1515284 -> Abstract

Brok J, Lopez-Yurda M, Tinteren HV, Treger TD, Furtwängler R, Graf N, Bergeron C, van den Heuvel-Eibrink MM, Pritchard-Jones K, Olsen ØE, de Camargo B, Verschuur A, Spreafico F
Relapse of Wilms' tumour and detection methods: a retrospective analysis of the 2001 Renal Tumour Study Group-International Society of Paediatric Oncology Wilms' tumour protocol database
Lancet Oncol. 2018 Jun 27. pii: S1470-2045(18)30293-6. doi: 10.1016/S1470-2045(18)30293-6 -> Abstract PubMed

Simon A, Gehrmann S, Wagenpfeil G, Wagenpfeil S

Risk Factors and Main Indications for Palivizumab Prophylaxis in a Second Season Population: Results from the German Synagis™ Registry 2009-2016

Pediatr Infect Dis J. 2018 Jul 16. doi: 10.1097/INF.0000000000002133, PMID: 30020201-> Abstract

Simon A, Dresbach T, Müller A

Methicillin-resistant Staphylococcus aureus Decolonization in Neonates and Children

Pediatr Infect Dis J. 2018 Jun;37(6):612-614. doi: 10.1097/INF.0000000000001982, PMID: 29762388, -> Abstract

Simon A, Gehrmann S, Wagenpfeil G, Wagenpfeil S

Use of Palivizumab in Germany - Report from the German Synagis™ Registry 2009 - 2016

Klin Padiatr. 2018 Apr 16. doi: 10.1055/a-0595-7771, PMID: 29660756 -> Abstract

Simon A, Gehrmann S, Wagenpfeil G, Wagenpfeil S

Palivizumab use in infants with Down syndrome-report from the German Synagis™ Registry 2009-2016

Eur J Pediatr. 2018 Jun;177(6):903-911. doi: 10.1007/s00431-018-3142-x, PMID: 29651734 -> Abstract

Simon A, Mock M, Graf N, von Müller L

Investigation of Clostridium difficile ribotypes in symptomatic patients of a German pediatric oncology center

Eur J Pediatr 177:403-408, 2018 -> Abstract

Fortmann I, Hartz A, Paul P, Pulzer F, Müller A, Böttger R, Proquitté H, Dawczynski K, Simon A, Rupp J, Herting E, Göpel W, Härtel C; German Neonatal Network

Antifungal Treatment and Outcome in Very-Low-Birth-Weight-Infants - A Population-Based Observational Study of the German Neonatal Network

Pediatr Infect Dis J. 2018 Mar 29. doi: 10.1097/INF.0000000000002001, PMID: 29601449 -> Abstract

Lehrnbecher T, Groll A, Agyeman P, Ammann RA, Attarbaschi A, Behrends U, Berger C, Hamprecht A, Hufnagel M, Laws HJ, Scheler M, Temme C, Vieth S, Simon A

Empfehlungen zur Diagnostik und Therapie bei krebskranken Kindern mit Fieber und Neutropenie – Vergleich zweier aktueller Leitlinien

Klin Padiatr. 2018 Apr;230(3):115-121, doi: 10.1055/s-0044-101953, PMID: 29589346 -> Abstract

Ebrahimi-Fakhari D, Zemlin M, Sauer H, Poryo M, Graf N, Meyer S

Erhebungseinheit für seltene pädiatrische Erkrankungen in Deutschland (ESPED) – 25 Jahre pädiatrische Epidemiologie: Eine Bestandsaufnahme

Klin Padiatr 230(04): 215-224, 2018 -> Abstract

Ebrahimi-Fakhari D, Lilian Lisa Mann LL, Poryo M, Graf N, von Kries R, Heinrich B; Ebrahimi-Fakhari D, Flotats-Bastardas M, Gortner L, Zemlin M, Meyer S

Incidence of Tuberous Sclerosis And Age At First Diagnosis: New Data And Emerging Trends From A National, Prospective Surveillance Study

Orphanet J Rare Disases, 13(1):117, 2018 -> Abstract

Furtwängler R, Graf N
Solide Tumoren bei Kindern und Jugendlichen: Prinzipien der onkologischen Therapie
In: von Schweinitz D., Ure B. (eds) Kinderchirurgie. Springer Reference Medizin, ISBN 978-3-662-53390-1 -> Abstract

Crico C, Renzi C, Graf N, Buyx A, Kondylakis H, Koumakis L, Pravettoni G
mHealth and telemedicine apps: in search of a common regulation
ecancer 12 853, 10.3332/ecancer.2018.853 -> Download

Schera F, Schäfer M, Bucur A, van Leeuwen J, Ngantchjon EH, Graf N, Kondylakis H, Koumakis L, Marias K, Kiefer S
iManageMyHealth and iSupportMyPatients: mobile decision support and health management apps for cancer patients and their doctors
ecancer 12 848, 10.3332/ecancer.2018.848 -> Download

Eichler H, Schleicher C, Heine S, Graf N, von Mackensen S
Feasibility and Results of a Mobile Haemophilia Outpatient Care Pilot Project
Hamostaseologie. 2018 Jul 11. doi: 10.1055/s-0038-1654721 -> Abstract PubMed

Wegert J, Vokuhl C, Collord G, Del Castillo Velasco-Herrera M, Farndon SJ, Guzzo C, Jorgensen M, Anderson J, Slater O, Duncan C, Bausenwein S, Streitenberger H, Ziegler B, Furtwängler R, Graf N, Stratton MR, Campbell PJ, Jones DT, Koelsche C, Pfister SM, Mifsud W, Sebire N, Sparber-Sauer M, Koscielniak E, Rosenwald A, Gessler M, Behjati S
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants
Nat Commun. 2018 Jun 18;9(1):2378. doi: 10.1038/s41467-018-04650-6 -> Abstract PubMed

Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Schick M, Keller U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP
REGGAE: a novel approach for the identification of key transcriptional regulators
Bioinformatics. 2018 May 7. doi: 10.1093/bioinformatics/bty372 -> Abstract PubMed

Dávila Fajardo R, Oldenburger E, Rübe C, López-Yurda M, Pritchard-Jones K, Bergeron C, Graf N, van Grotel M, van Tinteren H, Saunders D, van den Heuvel-Eibrink MM, Janssens GO, Oldenburger F
Evaluation of boost irradiation in patients with intermediate-risk stage III Wilms tumour with positive lymph nodes only: Results from the SIOP-WT-2001 Registry
Pediatr Blood Cancer. 2018 Apr 25:e27085. doi: 10.1002/pbc.27085 -> Abstract PubMed

Weiler G, Schwarz U, Rauch J, Rohm K, Lehr T, Theobald S, Kiefer S, Götz K, Och K, Pfeifer N, Handl L, Smola S, Ihle M, Turki AT, Beelen DW, Rissland J, Bittenbring J, Graf N
XplOit: An Ontology-Based Data Integration Platform Supporting the Development of Predictive Models for Personalized Medicine
Studies in Health Technology and Informatics, Volume 247. doi: 10.3233/978-1-61499-852-5-21 -> Download

Nemes K, Clément N, Kachanov D, Bens S, Hasselblatt M, Timmermann B, Schneppenheim R, Gerss J, Siebert R, Furtwängler R, Bourdeaut F, Frühwald MC; EU-RHAB consortium
The extraordinary challenge of treating patients with congenital rhabdoid tumors - a collaborative European effort
Pediatr Blood Cancer. 2018 Jun;65(6):e26999. doi: 10.1002/pbc.26999 -> Abstract PubMed

Gooskens SL, Graf N, Furtwängler R, Spreafico F, Bergeron C, Ramírez-Villar GL, Godzinski J, Rübe C, Janssens GO, Vujanic GM, Leuschner I, Coulomb-L'Hermine A, Smets AM, de Camargo B, Stoneham S, van Tinteren H, Pritchard-Jones K, van den Heuvel-Eibrink MM; International Society of Paediatric Oncology–Renal Tumour Study Group (SIOP–RTSG)
Position paper: Rationale for the treatment of children with CCSK in the UMBRELLA SIOP-RTSG 2016 protocol
Nat Rev Urol. 2018 Feb 27. doi: 10.1038/nrurol.2018.14 -> Abstract PubMed

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2017

Vokuhl C, Nourkami-Tutdibi N, Furtwängler R, Gessler M, Graf N, Leuschner I
ETV6-NTRK3 in congenital mesoblastic nephroma: A report of the SIOP/GPOH nephroblastoma study
Pediatr Blood Cancer. 2017 Dec 29. doi: 10.1002/pbc.26925 -> Abstract PubMed

Simon A, Mock M, Graf N, von Müller L
Investigation of Clostridium difficile ribotypes in symptomatic patients of a German pediatric oncology center
Eur J Pediatr. 2017 Dec 22. doi: 10.1007/s00431-017-3070-1 -> Abstract PubMed

Koumakis L, Sigdel K, Potamias G, Sfakianakis S, van Leeuwen J, Zacharioudakis G, Moustakis V, Zervakis M, Bucur A, Marias K, Graf N
Bridging miRNAs and pathway analysis in clinical decision support: a case study in nephroblastoma
Network Modeling Analysis in Health Informatics and Bioinformatics. 2015 Dec 1;4(1):30 -> Abstract

Ebrahimi-Fakhari D, Poryo M, Graf N, Zemlin M, Flotats-Bastardas M, Heine
G, Ragoschke-Schumm A, Meyer S
Optimized care in Patients with Rare Diseases: TSC at the Center for Rare
Diseases (ZSEUKS) at Saarland University Medical Center, Germany
Klin Padiatr. 2017 Nov;229(6):311-315. doi: 10.1055/s-0043-120069 -> Abstract PubMed

van den Heuvel-Eibrink MM, Hol JA, Pritchard-Jones K, van Tinteren H, Furtwängler R, Verschuur AC, Vujanic GM, Leuschner I, Brok J, Rübe C, Smets AM, Janssens GO, Godzinski J, Ramírez-Villar GL, de Camargo B, Segers H, Collini P, Gessler M, Bergeron C, Spreafico F, Graf N; International Society of Paediatric Oncology - Renal Tumour Study Group (SIOP–RTSG)
Position paper: Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocol
Nat Rev Urol. 2017 Oct 31. doi: 10.1038/nrurol.2017.163 -> Abstract PubMed

Hol JA, van den Heuvel-Eibrink MM, Graf N, Pritchard-Jones K, Brok J, van Tinteren H, Howell L, Verschuur A, Bergeron C, Kager L, Catania S, Spreafico F, Mavinkurve-Groothuis AMC
Irinotecan for relapsed Wilms tumor in pediatric patients: SIOP experience and review of the literature-A report from the SIOP Renal Tumor Study Group
Pediatr Blood Cancer. 2017 Oct 27. doi: 10.1002/pbc.26849. -> Abstract PubMed

Wegert J, Vokuhl C, Ziegler B, Ernestus K, Leuschner I, Furtwängler R, Graf N, Gessler M
TP53 alterations in Wilms tumour represent progression events with strong intratumour heterogeneity that are closely linked but not limited to anaplasia
J Pathol Clin Res. 2017 Aug 14;3(4):234-248. doi: 10.1002/cjp2.77 -> Abstract PubMed

Furtwängler R, Kager L, Melchior P, Rübe C, Ebinger M, Nourkami-Tutdibi N, Niggli F, Warmann S, Hubertus J, Amman G, Leuschner I, Vokuhl C, Graf N, Frühwald MC
High-dose treatment for malignant rhabdoid tumor of the kidney: No evidence for improved survival-The Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH) experience
Pediatr Blood Cancer. 2017 Aug 26. doi: 10.1002/pbc.26746 -> Abstract PubMed

Giannopoulou E, Furtwängler R, Bürger F, Schöndorf D, Gortner L, Meyer S
Novel Mutation in an Infant with Niemann-Pick Disease Type A/B
Klinische Pädiatrie 2016; 228(01): 47-48. doi: 10.1055/s-0035-1565239 -> Download

Spreafico F, van den Heuvel-Eibrink MM, Pritchard-Jones K, Bergeron C, Godzinski J, Smets A, Olsen O, Vujanic G, Rübe C, van Tinteren H, Gessler M, Graf N, SIOP Renal Tumour Study Group
Paediatric renal tumours: perspectives from the SIOP-RTSG
Nat Rev Urol. 2017 Jan;14(1):3-4. doi: 10.1038/nrurol.2016.247 -> Abstract PubMed

Kaysen A, Heintz-Buschart A, Muller EEL, Narayanasamy S, Wampach L, Laczny CC, Graf N, Simon A, Franke K, Bittenbring J, Wilmes P, Schneider JG
Integrated meta-omic analyses of the gastrointestinal tract microbiome in patients undergoing allogeneic hematopoietic stem cell transplantation
Transl Res. 2017 Jun 20. pii: S1931-5244(17)30069-5. doi: 10.1016/j.trsl.2017.06.008 -> Abstract PubMed

Ripperger T, Bielack SS, Borkhardt A, Brecht IB, Burkhardt B, Calaminus G, Debatin KM, Deubzer H, Dirksen U, Eckert C, Eggert A, Erlacher M, Fleischhack G, Frühwald MC, Gnekow A, Goehring G, Graf N, Hanenberg H, Hauer J, Hero B, Hettmer S, von Hoff K, Horstmann M, Hoyer J, Illig T, Kaatsch P, Kappler R, Kerl K, Klingebiel T, Kontny U, Kordes U, Körholz D, Koscielniak E, Kramm CM, Kuhlen M, Kulozik AE, Lamottke B, Leuschner I, Lohmann DR, Meinhardt A, Metzler M, Meyer LH, Moser O, Nathrath M, Niemeyer CM, Nustede R, Pajtler KW, Paret C, Rasche M, Reinhardt D, Rieß O, Russo A, Rutkowski S, Schlegelberger B, Schneider D, Schneppenheim R, Schrappe M, Schroeder C, von Schweinitz D, Simon T, Sparber-Sauer M, Spix C, Stanulla M, Steinemann D, Strahm B, Temming P, Thomay K, von Bueren AO, Vorwerk P, Witt O, Wlodarski M, Wössmann W, Zenker M, Zimmermann S, Pfister SM, Kratz CP
Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
Am J Med Genet A. 2017 Apr;173(4):1017-1037. doi: 10.1002/ajmg.a.38142 -> Abstract PubMed

Titze MI, Frank J, Ehrhardt M, Smola S, Graf N, Lehr T
A generic viral dynamic model to systematically characterize the interaction between oncolytic virus kinetics and tumor growth
Eur J Pharm Sci. 2017 Jan 15;97:38-46. doi: 10.1016/j.ejps.2016.11.003 -> Abstract PubMed

Furtwängler R, Schlotthauer U, Gärtner B, Graf N, Simon A
Nosocomial legionellosis and invasive aspergillosis in a child with T-lymphoblastic leukemia
Int J Hyg Environ Health. 2017 Jul;220(5):900-905. doi: 10.1016/j.ijheh.2017.05.002 -> Abstract PubMed

Rasche M, von Neuhoff C, Dworzak M, Bourquin JP, Bradtke J, Göhring G, Escherich G, Fleischhack G, Graf N, Gruhn B, Haas O, Klingebiel T, Kremens B, Lehrnbecher T, von Stackelberg A, Tchinda J, Zemanova Z, Thiede C, von Neuhoff N N, Zimmermann M, Creutzig U, Reinhardt D
Genotype-outcome correlations in pediatric AML: The impact of a monosomal karyotype in trial AML-BFM 2004
Leukemia. 2017 Apr 25. doi: 10.1038/leu.2017.121 -> Abstract PubMed

Garg AD, Vandenberk L, Fang S, Fasche T, Van Eygen S, Maes J, Van Woensel M, Koks C, Vanthillo N, Graf N, de Witte P, Van Gool S, Salven P, Agostinis P
Pathogen response-like recruitment and activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing
Cell Death Differ. 2017 Feb 24. doi: 10.1038/cdd.2017.15 -> Abstract PubMed

Bertoglio S, van Boxtel T, Goossens GA, Dougherty L, Furtwangler R, Lennan E, Pittiruti M, Sjovall K, Stas M
Improving outcomes of short peripheral vascular access in oncology and chemotherapy administration
J Vasc Access. 2017 Jan 25:0. doi: 10.5301/jva.5000668 -> Abstract PubMed

Gooskens SL, Houwing ME, Vujanic GM, Dome JS, Diertens T, Coulomb-l'Herminé A, Godzinski J, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM
Congenital mesoblastic nephroma fifty years after its recognition: A narrative review
Pediatr Blood Cancer. 2017;00:e26437. doi:10.1002/pbc.26437 -> Abstract

Creutzig U, Dworzak MN, Bochennek K, Faber J, Flotho C, Graf N, Kontny U, Rossig C, Schmid I, von Stackelberg A, Mueller JE, von Neuhoff C, Reinhardt D, von Neuhoff N
First experience of the AML-Berlin-Frankfurt-Münster group in pediatric patients with standard-risk acute promyelocytic leukemia treated with arsenic trioxide and all-trans retinoid acid
Pediatr Blood Cancer. 2017 Jan 23. doi: 10.1002/pbc.26461 -> Abstract PubMed

Kondylakis H, Koumakis L, Hänold S, Nwankwo I, Forgó N, Marias K, Tsiknakis M, Graf N
Donor's support tool: Enabling informed secondary use of patient's biomaterial and personal data
Int J Med Inform. 2017 Jan;97:282-292. doi: 10.1016/j.ijmedinf.2016.10.019 -> Abstract PubMed

Weiss K, Simon A, Graf N, Schöpe J, Oertel J, Linsler S
Clinical practice audit concerning antimicrobial prophylaxis in paediatric neurosurgery: results from a German paediatric oncology unit
Childs Nerv Syst. 2017 Jan;33(1):159-169. doi: 10.1007/s00381-016-3279-8 -> Abstract PubMed

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2016

Eggert A, Simon T, von Schweinitz D, Timmermann B, Graf N
Embryonale Bauchtumoren im Kindes- und Jugendalter
Onkologe (2016) 22: 940. doi:10.1007/s00761-016-0136-z -> Download

Chagtai T, Zill C, Dainese L, Wegert J, Savola S, Popov S, Mifsud W, Vujanić G, Sebire N, Le Bouc Y, Ambros PF, Kager L, O'Sullivan MJ, Blaise A, Bergeron C, Mengelbier LH, Gisselsson D, Kool M, Tytgat GA, van den Heuvel-Eibrink MM, Graf N, van Tinteren H, Coulomb A, Gessler M, Williams RD, Pritchard-Jones K
Gain of 1q As a Prognostic Biomarker in Wilms Tumors (WTs) Treated With Preoperative Chemotherapy in the International Society of Paediatric Oncology (SIOP) WT 2001 Trial: A SIOP Renal Tumours Biology Consortium Study
J Clin Oncol. 2016 Sep 10;34(26):3195-203. doi: 10.1200/JCO.2015.66.0001 -> Abstract PubMed

Apelt N, Hubertus J, Mayr D, Graf N, Furtwängler R, Von Schweinitz D, Kappler R
Association of FOXM1 expression with tumor histology and prognosis in Wilms tumor: Potential for a new prognostic marker
Oncology Letters 12.4 (2016): 2854-2859 -> Download

Bucur A, van Leeuwen J, Christodoulou N, Sigdel K, Argyri K, Koumakis L, Graf N, Stamatakos G
Workflow-driven clinical decision support for personalized oncology
BMC Med Inform Decis Mak. 2016 Jul 21;16 Suppl 2:87. doi: 10.1186/s12911-016-0314-3 -> Abstract PubMed

Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, Bernal-Delgado E, Blomberg N, Bock C, Conesa A, Del Signore S, Delogne C, Devilee P, Di Meglio A, Eijkemans M, Flicek P, Graf N, Grimm V, Guchelaar HJ, Guo YK, Gut IG, Hanbury A, Hanif S, Hilgers RD, Honrado Á, Hose DR, Houwing-Duistermaat J, Hubbard T, Janacek SH, Karanikas H, Kievits T, Kohler M, Kremer A, Lanfear J, Lengauer T, Maes E, Meert T, Müller W, Nickel D, Oledzki P, Pedersen B, Petkovic M, Pliakos K, Rattray M, I Màs JR, Schneider R, Sengstag T, Serra-Picamal X, Spek W, Vaas LA, van Batenburg O, Vandelaer M, Varnai P, Villoslada P, Vizcaíno JA, Wubbe JP, Zanetti G
Making sense of big data in health research: Towards an EU action plan
Genome Med. 2016 Jun 23;8(1):71. doi: 10.1186/s13073-016-0323-y -> Abstract PubMed

Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann RD, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel PG, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, Frühwald MC
Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007
Cancer Med. 2016 May 26. doi: 10.1002/cam4.741-> Abstract PubMed

Stöckel D, Kehl T, Trampert P, Schneider L, Backes C, Ludwig N, Gerasch A, Kaufmann M, Gessler M, Graf N, Meese E, Keller A, Lenhof HP
Multi-omics enrichment analysis using the GeneTrail2 web service
Bioinformatics. 2016 May 15;32(10):1502-8. doi: 10.1093/bioinformatics/btv770 -> Abstract PubMed

Kenny C, Bausenwein S, Lazaro A, Furtwängler R, Gooskens SL, van den Heuvel Eibrink M, Vokuhl C, Leuschner I, Graf N, Gessler M, O'Sullivan MJ
Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story
J Pathol. 2016 Apr;238(5):617-20. doi: 10.1002/path.4693 -> Abstract PubMed

Dietrich K, Leiss U, Griessmeier B, Wiener A, Minetzke-Gruner AC, Linhart D, Braungart R, Graf N, Wevers-Donauer G
Belastungserleben von Eltern krebskranker Kinder
Klin Padiatr 2016; 228: 149-156, DOI: 10.1055/s-0042-101345 -> Download

Anguita A, García-Remesal M, Graf N, Maojo V
A method and software framework for enriching private biomedical sources with data from public online repositories
J Biomed Inform. 2016 Apr;60:177-86. doi: 10.1016/j.jbi.2016.02.004 -> Abstract PubMed

Simon A, Furtwängler R, Graf N, Laws HJ, Voigt S, Piening B, Geffers C, Agyeman P, Ammann RA
Surveillance of bloodstream infections in pediatric cancer centers – what have we learned and how do we move on?
GMS Hyg Infect Control 2016; 11:Doc11 (20160512) -> Download

Müller S, Weickert J, Graf N
Automatic brain tumor segmentation with a fast Mumford-Shah algorithm
Proc. SPIE 9784, Medical Imaging 2016: Image Processing, 97842S (March 21, 2016); doi:10.1117/12.2214552 -> Abstract

Weiss K, Simon A, Graf N, Schöpe J, Meier CM
Clinical Practice Audit: Perioperative Antibiotic Prophylaxis in Paediatric Cancer Patients with Broviac Catheter Implantation
Klin Padiatr, DOI: 10.1055/s-0042-104415 -> Abstract

Ludwig N, Werner TV, Backes C, Trampert P, Gessler M, Keller A, Lenhof HP, Graf N, Meese E
Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes
Int. J. Mol. Sci. 2016, 17(4), 475; doi:10.3390/ijms17040475 -> Download

Schneider L, Stöckel D, Kehl T, Gerasch A, Ludwig N, Leidinger P, Huwer H, Tenzer S, Kohlbacher O, Hildebrandt A, Kaufmann M, Gessler M, Keller A, Meese E, Graf N, Lenhof HP
DrugTargetInspector: An assistance tool for patient treatment stratification
Int J Cancer. 2016 Apr 1;138(7):1765-76. doi: 10.1002/ijc.29897 -> Abstract PubMed

Pritchard-Jones K, Graf N, van Tinteren H, Craft A
Evidence for a delay in diagnosis of Wilms' tumour in the UK compared with Germany: implications for primary care for children
Arch Dis Child. 2016 Mar 6. pii: archdischild-2015-309212. doi: 10.1136/archdischild-2015-309212 -> Abstract PubMed

Gooskens SL, Kenny C, Lazaro A, O'Meara E, van Tinteren H, Spreafico F, Vujanic G, Leuschner I, Coulomb-L'Herminé A, Perotti D, de Camargo B, Bergeron C, Acha García T, Tanaka M, Pieters R, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM, O'Sullivan MJ
The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney
Genes Chromosomes Cancer. 2016 Feb;55(2):143-7. doi: 10.1002/gcc.22320 -> Abstract PubMed

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2015

Ludwig N, Nourkami-Tutdibi N, Backes C, Lenhof HP, Graf N, Keller A, Meese E
Circulating serum miRNAs as potential biomarkers for nephroblastoma
Pediatr Blood Cancer. 2015 Aug;62(8):1360-7. doi: 10.1002/pbc.25481 -> Abstract PubMed

Hubertus J, Günther B, Becker K, Graf N, Furtwängler R, Ferrari R, Gruhn B, Stahl R, von Schweinitz D, Stehr M
Development of hypertension is less frequent after bilateral nephron sparing surgery for bilateral Wilms tumor in a long-term survey
J Urol. 2015 Jan;193(1):262-6. doi: 10.1016/j.juro.2014.07.116 -> Abstract PubMed

Creutzig U, Dworzak MN, Zimmermann M, Bourquin JP, Gruhn B, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, Stackelberg AV, Starý J, Reinhardt D
Additional treatment with 2-Chloro-2-Deoxyadenosine during consolidation in children with high-risk acute myeloid leukemia does not improve survival
Leukemia. 2015 Nov;29(11):2260-3. doi: 10.1038/leu.2015.94 -> Abstract PubMed

Creutzig U, Dworzak M, Zimmermann M, Bourquin JP, Gruhn B, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, von Stackelberg A, Stray J, Reinhardt D
Randomised Introduction of 2-CDA as Intensification during Consolidation for Children with High-risk AML--results from Study AML-BFM 2004
Klin Padiatr. 2015 May;227(3):116-22. doi: 10.1055/s-0035-1548816 -> Abstract PubMed

Kuchinke W, Ohmann C, Stenzhorn H, Anguista A, Sfakianakis S, Graf N, Demotes J
Ensuring sustainability of software tools and services by cooperation with a research infrastructure
Personalized Medicine, Vol. 13, No. 1, Pages 43-55 doi: 10.2217/pme.15.43 -> Download

Furtwängler R, Laux C, Graf N, Simon A
Impact of a modified Broviac maintenance care bundle on bloodstream infections in paediatric cancer patients
GMS Hyg Infect Control. 2015 Nov 16;10:Doc15. doi: 10.3205/dgkh000258 -> Abstract PubMed

Sfakianaki P, Koumakis L, Sfakianakis S, Iatraki G, Zacharioudakis G, Graf N, Marias K, Tsiknakis M
Semantic biomedical resource discovery: a Natural Language Processing framework
BMC Med Inform Decis Mak. 2015 Sep 30;15:77. doi: 10.1186/s12911-015-0200-4 -> Abstract PubMed

Dome JS, Graf N, Geller JI, Fernandez CV, Mullen EA, Spreafico F, Van den Heuvel-Eibrink M, Pritchard-Jones K
Advances in Wilms Tumor Treatment and Biology: Progress Through International Collaboration
J Clin Oncol. 2015 Aug 24. pii: JCO.2015.62.1888 -> Abstract PubMed

Tulla M, Berthold F, Graf N, Stefan R, von Schweinitz D, Spix C, Kaatsch P
Incidence, Trends, and Survival of Children with Embryonal Tumors
Pediatrics 136:e623-e632, 2015, doi: 10.1542/peds.2015-0224 -> Abstract

Pritchard-Jones K, Bergeron C, de Camargo B, van den Heuvel-Eibrink MM, Acha T, Godzinski J, Oldenburger F, Boccon-Gibod L, Leuschner I, Vujanic G, Sandstedt B, de Kraker J, van Tinteren H, Graf N, on behalf of the SIOP Renal Tumours Study Group
Omission of doxorubicin from the treatment of stage II–III, intermediate-risk Wilms' tumour (SIOP WT 2001): an open-label, non-inferiority, randomised controlled trial
The Lancet, Published online July 9, 2015 dx.doi.org/10.1016/S0140-6736(14)62395-3 -> Download

Williams RD, Chagtai T, Alcaide-German M, Apps J, Wegert J, Popov S, Vujanic G, van Tinteren H, van den Heuvel-Eibrink MM, Kool M, de Kraker J, Gisselsson D, Graf N, Gessler M, Pritchard-Jones K
Multiple mechanisms of MYCN dysregulation in Wilms tumour
Oncotarget. 2015 Mar 30;6(9):7232-43 -> Abstract PubMed

SIOP Renal Tumor Study Group (RTSG), van den Heuvel-Eibrink MM, Pritchard-Jones K, van Tinteren H, Graf N
Response to letter commenting on "Outcome of localised blastemal-type Wilms tumour patients treated according to intensified treatment in the SIOP WT 2001 protocol, a report of the SIOP Renal Tumour Study Group (SIOP-RTSG)"
Eur J Cancer. 2015 May;51(8):995-6. doi: 10.1016/j.ejca.2015.03.006 -> Abstract PubMed

Lehnhardt A, Karnatz C, Ahlenstiel-Grunow T, Benz K, Benz MR, Budde K, Büscher AK, Fehr T, Feldkötter M, Graf N, Höcker B, Jungraithmayr T, Klaus G, Koehler B, Konrad M, Kranz B, Montoya CR, Müller D, Neuhaus TJ, Oh J, Pape L, Pohl M, Royer-Pokora B, Querfeld U, Schneppenheim R, Staude H, Spartà G, Timmermann K, Wilkening F, Wygoda S, Bergmann C, Kemper MJ
Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1
Clin J Am Soc Nephrol. 2015 May 7;10(5):825-31. doi: 10.2215/CJN.10141014 -> Abstract PubMed

Müller S, David R, Marias K, Graf N
The Standardized Histogram Shift of T2 Magnetic Resonance Image (MRI) Signal Intensities of Nephroblastoma Does Not Predict Histopathological Diagnostic Information
Cancer Informatics 2015:Suppl. 4 1-5 doi: 10.4137/CIN.S19340 -> Download

Koks CA, Garg AD, Ehrhardt M, Riva M, Vandenberk L, Boon L, De Vleeschouwer S, Agostinis P, Graf N, Van Gool SW
Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death
Int J Cancer. 2015 Mar 1;136(5):E313-25. doi: 10.1002/ijc.29202 -> Abstract PubMed

Ammann RA, Laws HJ, Schrey D, Ehlert K, Moser O, Dilloo D, Bode U, Wawer A, Schrauder A, Cario G, Laengler A, Graf N, Furtwängler R, Simon A
Bloodstream infection in paediatric cancer centres-leukaemia and relapsed malignancies are independent risk factors
Eur J Pediatr. 2015 Mar 26 -> Abstract PubMed

Anguita A, García-Remesal M, de la Iglesia D, Graf N, Maojo V
Toward a view-oriented approach for aligning RDF-based biomedical repositories
Methods Inf Med. 2015;54(1):50-5. doi: 10.3414/ME13-02-0020 -> Abstract PubMed

Graf N
Personalized Medicine and the way to CHIC. A clinical perspective
Minerva Urol Nefrol 67 (Suppl 1):45, 2015

Mavinkurve-Groothuis AM, van den Heuvel-Eibrink MM, Tytgat GA, van Tinteren H, Vujanic G, Pritchard-Jones KL, Howell L, Graf N, Bergeron C, Acha T, Catania S, Spreafico F
Treatment of relapsed Wilms tumour (WT) patients: Experience with topotecan. A report from the SIOP Renal Tumour Study Group (RTSG)
Pediatr Blood Cancer. 2015 Apr;62(4):598-602. doi: 10.1002/pbc.25357 -> Abstract PubMed

Godzinski J, Graf N, Audry G
Current concepts in surgery for Wilms tumor - the risk and function-adapted strategy
Eur J Pediatr Surg. 2014 Dec;24(6):457-60. doi: 10.1055/s-0034-1396425 -> Abstract PubMed

Backes C, Harz C, Fischer U, Schmitt J, Ludwig N, Petersen BS, Mueller SC, Kim YJ, Wolf NM, Katus HA, Meder B, Furtwängler R, Franke A, Bohle R, Henn W, Graf N, Keller A, Meese E
New insights into the genetics of glioblastoma multiforme by familial exome sequencing
Oncotarget. 2014 Dec 10 -> Abstract PubMed

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, Keller A, Grimm C, Kneitz S, Williams RD, Chagtai T, Pritchard-Jones K, van Sluis P, Volckmann R, Koster J, Versteeg R, Acha T, O'Sullivan MJ, Bode PK, Niggli F, Tytgat GA, van Tinteren H, van den Heuvel-Eibrink MM, Meese E, Vokuhl C, Leuschner I, Graf N, Eils R, Pfister SM, Kool M, Gessler M
Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors
Cancer Cell, Volume 27, Issue 2, 9 February 2015, Pages 298–311, doi: 10.1016/j.ccell.2015.01.002 -> Download

Stamatakos G, Dionysiou D, Misichroni F, Graf N, van Gool S, Bohle R, Dong F, Viceconti M, Marias K, Sakkalis V, Forgo N, Radhakrishnan R, Byrne H, Guiot C, Buechler P, Neri E, Bucur A, de Bono B, Testi D, Tsiknakis M on behalf of the CHIC consortium
Computational Horizons In Cancer (CHIC): Developing Meta- and Hyper-Multiscale Models and Repositories for In Silico Oncology - a Brief Technical Outline of the Project
In G. Stamatakos and D. Dionysiou (Eds): Proc. 2014 6th Int. Adv. Res. Workshop on In Silico Oncology and Cancer Investigation - The CHIC Project Workshop (IARWISOCI), Athens, Greece, Nov.3-4, 2014, pp.9-13, ISBN: 978-618-80348-1-5 -> Download

David R, Dong F, Braun Y, Graf N
MyHealthAvatar Survey: Scenario Based User Needs and Requirements
In G. Stamatakos and D. Dionysiou (Eds): Proc. 2014 6th Int. Adv. Res. Workshop on In Silico Oncology and Cancer Investigation - The CHIC Project Workshop (IARWISOCI), Athens, Greece, Nov.3-4, 2014, pp.69-72, ISBN: 978-618-80348-1-5 -> Download

Koks C AE, De Vleeschouwer S, Graf N, Van Gool SW
Immune Suppression during Oncolytic Virotherapy for High-Grade Glioma; Yes or No?
J. Cancer 2015; 6(3): 203-217. doi:10.7150/jca.10640 -> Download

van den Heuvel-Eibrink MM, van Tinteren H, Bergeron C, Coulomb-L'Hermine A, de Camargo B, Leuschner I, Sandstedt B, Acha T, Godzinski J, Oldenburger F, Gooskens SL, de Kraker J, Vujanic GM, Pritchard-Jones K, Graf N
Outcome of localised blastemal-type Wilms tumour patients treated according to intensified treatment in the SIOP WT 2001 protocol, a report of the SIOP Renal Tumour Study Group (SIOP-RTSG)
Eur J Cancer. 2015 Jan 12. pii: S0959-8049(14)01171-X. doi: 10.1016/j.ejca.2014.12.011 -> Abstract PubMed

Wieland I, Kentouche K, Jentzsch M, Lothschütz D, Norbert G, Karl-Walter S
Long-term remission of recurrent thrombotic thrombocytopenic purpura (TTP) after rituximab in children and young adults
Pediatric Blood & Cancer, 2015 Jan 13. doi: 10.1002/pbc.25398 -> Download

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2014

Illhardt T, Ebinger M, Schwarze CP, Feuchtinger T, Furtwängler R, Schlegel PG, Klingebiel T, Greil J, Beck JF, Handgretinger R, Lang P
Children with relapsed or refractory nephroblastoma: favorable long-term survival after high-dose chemotherapy and autologous stem cell transplantation
Klin Padiatr. 2014 Nov;226(6-7):351-6. doi: 10.1055/s-0034-1390504 -> Abstract PubMed

Müller K, Scheithauer H, Pietschmann S, Hoffmann M, Rössler J, Graf N, Baumert BG, Christiansen H, Kortmann RD, Kramm CM, von Bueren AO
Reirradiation as part of a salvage treatment approach for progressive non-pontine pediatric high-grade gliomas: preliminary experiences from the German HIT-HGG study group
Radiat Oncol. 2014 Aug 12;9:177. doi: 10.1186/1748-717X-9-177 -> Abstract PubMed

Furtwängler R, Nourkami-Tutdibi N, Leuschner I, Vokuhl C, Niggli F, Kager L, Ebinger M, Frühwald MC, Graf N; GPOH Nephroblastoma Study Committee
Malignant rhabdoid tumor of the kidney: significantly improved response to pre-operative treatment intensified with doxorubicin
Cancer Genet. 2014 Sep;207(9):434-6. doi: 10.1016/j.cancergen.2014.07.001 -> Abstract PubMed

Simon A, Manoha C, Müller A, Schildgen O
Human Metapneumovirus and Its Role in Childhood Respiratory Infections
Current Pediatrics Reports, September 2014, Volume 2, Issue 3, pp 156-165. doi: 10.1007/s40124-014-0048-6  -> Download

Mavinkurve-Groothuis AM, van den Heuvel-Eibrink MM, Tytgat GA, van Tinteren H, Vujanic G, Pritchard-Jones KL, Howell L, Graf N, Bergeron C, Acha T, Catania S, Spreafico F
Treatment of relapsed Wilms tumour (WT) patients: Experience with topotecan. A report from the SIOP Renal Tumour Study Group (RTSG)
Pediatr Blood Cancer. 2014 Dec 29. doi: 10.1002/pbc.25357 -> Abstract PubMed

Schöndorf D, von Bernuth H, Simon A, Schneider G, Kölsch U, Schwarz K, Meier CM, Groe-Onnebrink J, Gortner L, Rohrer TR
Liver abscess complicated by diaphragm perforation and pleural empyema leads to the discovery of interleukin-1 receptor-associated kinase 4 deficiency
Pediatr Infect Dis J. 2014 Jul;33(7):767-9. doi: 10.1097/INF.0000000000000277 -> Abstract PubMed

Warmann SW, Godzinski J, van Tinteren H, Heij H, Powis M, Sandstedt B, Graf N, Fuchs J, Surgical Panel of the SIOP Renal Tumor Strategy Group
Minimally invasive nephrectomy for Wilms tumors in children - data from SIOP 2001
J Pediatr Surg. 2014 Nov;49(11):1544-8. doi: 10.1016/j.jpedsurg.2014.06.005 -> Abstract PubMed

Streif W, Knöfler R1, Eberl W, Andres O, Bakchoul T, Bergmann F, Beutel K, Dittmer R, Gehrisch S, Gottstein S, Halimeh S, Haselböck J, Hassenpflug WA, Heine S, Holzhauer S, King S, Kirchmaier CM, Krause M, Kreuz W, Lösche W, Mahnel R, Maurer M, Nimtz-Talaska A, Olivieri M, Rott H, Schambeck ChM, Schedel A, Schilling FH, Schmugge M, Schneppenheim R, Scholz U, Scholz T, Schulze H, Siegemund A, Strauß G, Sykora KW, Wermes C, Wiegering V, Wieland I, Zieger B, Zotz RB
Therapy of inherited diseases of platelet function. Interdisciplinary S2K guideline of the Permanent Paediatric Committee of the Society of Thrombosis and Haemostasis Research (GTH e. V.)
Hamostaseologie. 2014 Nov 5;34(4):269-75. doi: 10.5482/HAMO-2014040001 -> Abstract PubMed

Wilde JC, Aronson DC, Sznajder B, Van Tinteren H, Powis M, Okoye B, Cecchetto G, Audry G, Fuchs J, Schweinitz DV, Heij H, Graf N, Bergeron C, Pritchard-Jones K, Van Den Heuvel-Eibrink M, Carli M, Oldenburger F, Sandstedt B, De Kraker J, Godzinski J
Nephron sparing surgery (NSS) for unilateral wilms tumor (UWT): The Siop 2001 experience
Pediatr Blood Cancer. 2014 Aug 23. doi: 10.1002/pbc.25185 -> Abstract PubMed

Yogesh KS, Graf N
Management of recurrent Wilms' tumor
JIMSA 27:91-94, 2014 -> Download

Gooskens SL, Furtwängler R, Spreafico F, van Tinteren H, de Kraker J, Vujanic GM, Leuschner I, Coulomb-L'Herminé A, Godzinski J, Schleiermacher G, Stoneham S, Bergeron C, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM
Treatment and outcome of patients with relapsed clear cell sarcoma of the kidney: a combined SIOP and AIEOP study
Br J Cancer. 2014 Jul 15;111(2):227-233. doi: 10.1038/bjc.2014.291 -> Abstract PubMed

Atteby Yao JJ, Graf N, Vujanic GM
Nephroblastoma. In: Stefan DC, Rodriguez-Galindo C (eds.) Pediatric Hematology-Oncology in Countries with limited resources: A practical Manual
DOI 10.1007/978-1-4614-3891-5_24, Springer Science+Business Media, New York, 2014, S. 355-364 -> Download

Wessalowski R, Furtwängler R, Graf N
Tumoren des Urogenitalsystems. In: Therapie der Krankheiten im Kindes- und Jugendalter. Hrsg: Reinhardt D, Nicolai T, Zimmer KP
9. Überarbeitete und erweiterte Auflage, Springer Verlag, Berlin, Heidelberg, 2014, S. 537-545; ISBN: 978-3-642-41813-6 -> Download

Viceconti M, Graf N
Toward Clinical Deployment: Verification and Validation of Models. In: Computational Biomedicine: Modelling the Human Body; Hrsg.: Coveney P, Diaz-Zuccarni V, Hunter P, Viceconti M
Oxford, Oxford University Press, 2014, S. 232-251 -> Download

Seeringer A, Bartelheim K, Kerl K, Hasselblatt M, Leuschner I, Rutkowski S, Timmermann B, Kortmann RD, Koscielniak E, Schneppenheim R, Warmuth-Metz M, Gerß J, Siebert R, Graf N, Boos J, Frühwald MC
Feasibility of intensive multimodal therapy in infants affected by rhabdoid tumors - experience of the EU-RHAB registry
Klin Padiatr. 2014 May;226(3):143-8. doi: 10.1055/s-0034-1368719 -> Abstract PubMed

Hana A, Nitish Gunness VR, Berthold C, Hana A, Bofferding L, Neuhaeuser C, Scalais E, Kieffer I, Feiden W, Graf N, Boecher-Schwarz H, Hertel F
Supratentorial embryonal tumor with abundant neuropil and true rosettes (ETANTR)
Neuro Oncol 16 (suppl1):i127-i136 (RTU-029), 2014 -> Download

Müller K, Hoffmann M, Seidel C, Warmuth-Metz M, Pietsch T, Kordes U, Sander A, Rössler J, Graf N, Scheithauer H, Kortmann RD, Kramm C, Büren AO
Salvage treatment of progressive Non-pontine Pediatric high-grade gliomas by re-irradiation: Preliminary experiences from the German HIT-HGG Study Group
Neuro Oncol 16 (suppl1):i117-i122 (RO-015), 2014 -> Download

Koks C, Garg A, Ehrhardt M, Riva M, De Vleeschouwer S, Agostinis P, Graf N, van Gool S
Newcastle disease virotherapy, a novel immunotherapeutic approach for high grade glioma
Neuro Oncol 16 (suppl1):i40-i59 (HG-004), 2014 -> Download

Benesch M, Warmuth-Metz M, von Büren AO, Hoffmann M, Pietsch T, Kortmann RD, Eyrich M, Graf N, Rutkowski S, Frühwald MC, Faber J, Kramm C
Centrally reviewed gliomatosis cerebri in children and Adolescents: A retrospective Analysis from the HIT-HGG database
Neuro Oncol 16 (suppl1):i40-i59 (HG-011), 2014 -> Download

Dome JS, Perlman EJ, Graf N
Risk stratification for wilms tumor: current approach and future directions
Am Soc Clin Oncol Educ Book. 2014;34:215-23. doi: 10.14694/EdBook_AM.2014.34.215 -> Abstract PubMed

Furtwängler R, Schmolze M, Gräber S, Leuschner I, Amann G, Schenk JP, Niggli F, Kager L, Schweinitz DV, Graf N
Pretreatment for Bilateral Nephroblastomatosis is an Independent Risk Factor for Progressive Disease in Patients with Stage V Nephroblastoma
Klin Padiatr. 2014 May;226(3):175-181 -> Abstract PubMed

Brecht IB, Bremensdorfer C, Schneider DT, Frühwald MC, Offenmüller S, Mertens R, Vorwerk P, Koscielniak E, Bielack SS, Benesch M, Hero B, Graf N, On Schweinitz D, Kaatsch P
Rare malignant pediatric tumors registered in the German Childhood Cancer Registry 2001-2010
Pediatr Blood Cancer. 2014 Jul;61(7):1202-1209. doi: 10.1002/pbc.24997 -> Abstract PubMed

Tsiknakis M, Promponas VJ, Graf N, Wang MD, Wong STC, Bourbakis N, Pattichis CS
Guest editorial: Computational Solutions to Large-Scale Data Management and Analysis in Translational and Personalized Medicine
IEEE J Biomedical and Health Informatics 18(3): 720-721, 2014, DOI: 10.1109/JBHI.2014.2315513 -> Abstract

Schuler N, Palm J, Kaiser M, Betten D, Furtwängler R, Rübe C, Graf N, Rübe CE
DNA-Damage Foci to Detect and Characterize DNA Repair Alterations in Children Treated for Pediatric Malignancies
PLoS One. 2014 Mar 17;9(3):e91319. doi: 10.1371/journal.pone.0091319. eCollection 2014 -> Abstract PubMed

Graf N, Furtwängler R
Preoperative chemotherapy and local stage III in nephroblastoma
Transl Pediatr 2014;3(1):4-11. doi: 10.3978/j.issn.2224-4336.2013.12.02 -> Download

Graf N
The personalized medicine project
Ecancermedicalscience. - 8. 2014, Special issue -> Download

Weiler G, Schröder C, Schera F, Dobkowicz M, Kiefer S, Heidtke K R, Hänold S, Nwankwo I, Forgó N, Stanulla M, Eckert C, Graf N
p-BioSPRE - An ICT Framework for Transnational Biomaterial Sharing and Access
Ecancermedicalscience. - 8. 2014, Special issue, 401, DOI: 10.3332/ecancer.2014.401 -> Download

Schera F, Weiler G, Neri E, Kiefer S, Graf N
The p-medicine portal - A collaboration platform for research in personalized medicine
Ecancermedicalscience. - 8. 2014, Special issue, 398, DOI: 10.3332/ecancer.2014.398 -> Download

Marie-Luise Christ-Neumann, Ana Escrich, Alberto Anguita, Holger Stenzhorn, Marian Taylor, Hena Ramay, Stefan Rüpping, Christian Krauth, Wolfgang Kuchinke, Graf N, Simona Rossi
Usability on the p-medicine infrastructure: an extended usability concept
Ecancermedicalscience. - 8. 2014, Special issue, 399, DOI: 10.3332/ecancer.2014.399 -> Download

Sakkalis V, Sfakianakis S, Tzamali E, Marias K, Stamatakos G, Misichroni F, Ouzounoglou E, Kolokotroni E, Dionysiou D, Johnson D, McKeever S, Graf N
Web-based workflow planning platform supporting the design and execution of complex multiscale cancer models
IEEE Journal of Biomedical and Health Informatics (J-BHI) 18:824-831, 2014. ISSN: 2168-2194. DOI: 10.1109/JBHI.2013.2297167 -> Abstract

Furtwängler R, Hauschild A-C, Hübel J, Rakicioglou H, Bödeker B, Maddula S, Simon A, Baumbach J I
Signals of neutropenia in human breath?
Int. J. Ion Mobil. Spec. (2014) 17:19–23, DOI 10.1007/s12127-014-0145-9 -> Download

Graf N
Biomarker and Wilms Tumor. Highlight
Pediatr Blood Cancer, Volume 61, Issue 2, pages 185–186, February 2014 -> Download

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2013

Berger M, Fernandez-Pineda I, Cabello R, Ramírez-Villar GL, Márquez-Vega C, Nustede R, Linderkamp C, Schmid I, Neth O, Graf N, de Agustin JC, von Schweinitz D, Lacher M, Hubertus J
The relationship between the site of metastases and outcome in children with stage IV Wilms Tumor: data from 3 European Pediatric Cancer Institutions
J Pediatr Hematol Oncol. 2013 Oct;35(7):518-24. doi: 10.1097/MPH.0b013e318288634d -> Abstract PubMed

Stamatakos GS, Kolokotroni E, Dionysiou D, Veith C, Kim YJ, Franz A, Marias K, Sabczynski J, Bohle R, Graf N
In silico oncology: Exploiting clinical studies to clinically adapt and validate multiscale oncosimulators
Conf Proc IEEE Eng Med Biol Soc. 2013;2013:5545-9. doi: 10.1109/EMBC.2013.6610806 -> Abstract PubMed

Stamatakos G, Dionysiou D, Lunzer A, Belleman R, Kolokotroni E, Georgiadi E, Erdt M, Pukacki J, Rueping S, Giatili S, d'Onofrio A, Sfakianakis S, Marias K, Desmedt C, Tsiknakis M, Graf N
The Technologically Integrated Oncosimulator: Combining Multiscale Cancer Modeling with Information Technology in the In Silico Oncology Context
IEEE J Biomed Health Inform. 2013 Oct 2 -> Abstract PubMed

Furtwängler R, Gooskens SL, van Tinteren H, de Kraker J, Schleiermacher G, Bergeron C, de Camargo B, Acha T, Godzinski J, Sandstedt B, Leuschner I, Vujanic GM, Pieters R, Graf N, van den Heuvel-Eibrink MM
Clear cell sarcomas of the kidney registered on International Society of Pediatric Oncology (SIOP) 93-01 and SIOP 2001 protocols: a report of the SIOP Renal Tumour Study Group
Eur J Cancer. 2013 Nov;49(16):3497-506. doi: 10.1016/j.ejca.2013.06.036 -> Abstract PubMed

Cases M, Furlong LI, Albanell J, Altman RB, Bellazzi R, Boyer S, Brand A, Brookes AJ, Brunak S, Clark TW, Gea J, Ghazal P, Graf N, Guigó R, Klein TE, López-Bigas N, Maojo V, Mons B, Musen M, Oliveira JL, Rowe A, Ruch P, Shabo A, Shortliffe EH, Valencia A, van der Lei J, Mayer MA, Sanz F
Improving data and knowledge management to better integrate health care and research
J Intern Med. 2013 Oct;274(4):321-8. doi: 10.1111/joim.12105 -> Abstract PubMed

Creutzig U, Zimmermann M, Bourquin JP, Dworzak MN, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, Ritter J, Sander A, Schrauder A, von Stackelberg A, Starý J, Reinhardt D
Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004
Blood. 2013 Jul 4;122(1):37-43. doi: 10.1182/blood-2013-02-484097 -> Abstract PubMed

Bucur A, van Leeuwen J, Cirstea TC, Graf N
Clinical decision support framework for validation of multiscale models and personalization of treatment in oncology
IEEE 13th International Conference on , vol., no., pp.1,4, 10-13 Nov. 2013 doi: 10.1109/BIBE.2013.6701695 -> Download

Simon A, Beutel K; Laws HJ, Trautmann M, Greiner J, Graf N
Evidenzbasierte Empfehlungen zur Anwendung dauerhaft implantierter, zentralvenöser Zugänge in der pädiatrischen Onkologie
2013, mhp. ISBN: 978-3-88681-120-5

Rüping S, Graf N
Datenanalyse: Big Data in der Medizin
Dtsch Arztebl 2013; 110(41): A-1926 / B-1701 / C-1665 -> Download

Gooskens SL, Furtwaengler R, Van Tinteren H, De Kraker J, Schleiermacher G, Bergeron C, Spreafico F, De Camargo B, Acha T, Godzinski J, Sandstedt B, Leuschner I, Vujanic G, Pieters R, Graf N, Van den Heuvel-Eibrink MM
CLEAR CELL SARCOMA OF THE KIDNEY (CCSK) REGISTERED ON SIOP 93-01 AND SIOP 2001 PROTOCOLS: A REPORT OF THE SIOP RENAL TUMOUR STUDY GROUP
Pediatr Blood Cancer DOI 10.1002/pbc -> Abstract (O-0079)

Van den Heuvel-Eibrink MM, Van Tinteren H, Bergeron C, Coulombe A, De Camargo B, Leuschner I, Sandstedt B, Acha T, Gooskens SL, Furtwaengler R, De Kraker J, Vujanic GM, Pritchard-Jones K, Graf N
OUTCOME OF BLASTEMAL TYPE NEPHROBLASTOMA PATIENTS TREATED ACCORDING TO INTENSIFIED TREATMENT IN THE SIOP 2001 PROTOCOL, A REPORT OF THE SIOP RENAL TUMOUR STUDY GROUP (RTSG)
Pediatr Blood Cancer DOI 10.1002/pbc -> Abstract (O-0080)

Wolff J, Kwiecien R, Pietsch T, Faldum A, Kortmann R, Warmuth Metz M, Rutkowski S, Slavc I, Graf N, Gnekow A, Kuehl J, Korten I, Kramm C
HIGH-DOSE METHOTREXATE IMPROVED SURVIVAL IN PEDIATRIC GLIOBLASTOMA: RESULTS OF HIT-GBM-D
Pediatr Blood Cancer DOI 10.1002/pbc -> Abstract (P-0345)

Graf N, Braun Y, Nwankwo I, Hänold S, Neri E, Claerhout B, Forg N
DEALING WITH DATA SAFETY AND SECURITY IN TRANSLATIONAL AND PERSONALIZED MEDICINE
Pediatr Blood Cancer DOI 10.1002/pbc -> Abstract (P-0406)

Simon A
Umgang mit Tierkontakten bei immunsupprimierten Kindern
HygMed 2013; 38 [7/8]: 321–324 -> Abstract

Malogolowkin M, Spreafico F, Dome JS, van Tinteren H, Pritchard-Jones K, van den Heuvel-Eibrink MM, Bergeron C, de Kraker J, Graf N; COG Renal Tumors Committee and the SIOP Renal Tumor Study Group
Incidence and outcomes of patients with late recurrence of Wilms' tumor
Pediatr Blood Cancer. 2013 Oct;60(10):1612-5. doi: 10.1002/pbc.24604 -> Abstract PubMed

Rossig C, Juergens H, Schrappe M, Moericke A, Henze G, von Stackelberg A, Reinhardt D, Burkhardt B, Woessmann W, Zimmermann M, Gadner H, Mann G, Schellong G, Mauz-Koerholz C, Dirksen U, Bielack S, Berthold F, Graf N, Rutkowski S, Calaminus G, Kaatsch P, Creutzig U
Effective childhood cancer treatment: The impact of large scale clinical trials in Germany and Austria
Pediatr Blood Cancer. 2013 Oct;60(10):1574-81. doi: 10.1002/pbc.24598. Epub 2013 Jun 5 -> Abstract PubMed

Stamatakos GS, Graf N, Radhakrishnan R
Multiscale Cancer Modeling and In Silico Oncology: Emerging Computational Frontiers in Basic and Translational Cancer Research
J Bioengineer & Biomedical Sci 3: e114. doi:10.4172/2155-9538.1000e114 -> Download

Simon A, Graf N, Furtwängler R
Results of a Multicentre Survey Evaluating Clinical Practice of Port and Broviac Management in Paediatric Oncology
Klin Padiatr. 2013 May;225(3):145-151 -> Abstract PubMed

Gottschling S, Gronwald B, Schmitt S, Schmitt C, Längler A, Leidig E, Meyer S, Baan A, Shamdeen MG, Berrang J, Graf N
Use of complementary and alternative medicine in healthy children and children with chronic medical conditions in Germany
Complement Ther Med. 2013 Apr;21 Suppl 1:S61-9. doi: 10.1016/j.ctim.2011.06.001 -> Abstract PubMed

Schultze-Florey RE, Graf N, Vorwerk P, Koscielniak E, Schneider DT, Kratz CP
DICER1 Syndrome: A New Cancer Syndrome
Klin Padiatr. 2013 May;225(3):177-178 -> Abstract PubMed

Johnson D, McKeever S, Stamatakos G, Dionysiou D, Graf N, Sakkalis V, Marias K, Wang Z, Deisboeck TS
Dealing with diversity in computational cancer modeling
Cancer Inform. 2013 May 7;12:115-24. doi: 10.4137/CIN.S11583. Print 2013 -> Abstract PubMed

Jefferys BR, Nwankwo I, Neri E, Chang David CW, Lev S, Hänold S, Graf N, Forgó N, Coveney P
Navigating legal constraints in clinical data warehousing: a case study in personalized medicine
Interface Focus 3:20120088, 2013 -> Full Paper

Coveney PV, Díaz-Zuccarini V, Graf N, Hunter P, Kohl P, Tegner J, Viceconti M
Integrative approaches to computational biomedicine
Interface Focus 3:20130003, 2013 -> Full Paper

Schetzek S, Heinen F, Kruse S, Borggraefe I, Bonfert M, Gaul C, Gottschling S, Ebinger F
Headache in children: update on complementary treatments
Neuropediatrics. 2013 Feb;44(1):25-33. doi: 10.1055/s-0032-1333435 -> Abstract PubMed

Benesch M, von Bueren AO, Dantonello T, von Hoff K, Pietsch T, Leuschner I, Claviez A, Bierbach U, Kropshofer G, Korinthenberg R, Graf N, Suttorp M, Kortmann RD, Friedrich C, von der Weid N, Kaatsch P, Klingebiel T, Koscielniak E, Rutkowski S
Primary intracranial soft tissue sarcoma in children and adolescents: a cooperative analysis of the European CWS and HIT study groups
J Neurooncol. 2013 Feb;111(3):337-45. doi: 10.1007/s11060-012-1020-3 -> Abstract PubMed

Watson JA, Bryan K, Williams R, Popov S, Vujanic G, Coulomb A, Boccon-Gibod L, Graf N, Pritchard-Jones K, O'Sullivan M
miRNA Profiles as a Predictor of Chemoresponsiveness in Wilms' Tumor Blastema
PLoS One. 2013;8(1):e53417. doi: 10.1371/journal.pone.0053417 -> Abstract PubMed

Petersen I, Spix C, Kaatsch P, Graf N, Janka G, Kollek R
Parental informed consent in pediatric cancer trials: A population-based survey in Germany
Pediatr Blood Cancer. 2013 Mar;60(3):446-50. doi: 10.1002/pbc.24330 -> Abstract PubMed

Ha TC, Spreafico F, Graf N, Dallorso S, Dome JS, Malogolowkin M, Furtwängler R, Hale JP, Moroz V, Machin D, Pritchard-Jones K
An international strategy to determine the role of high dose therapy in recurrent Wilms' tumour
Eur J Cancer. 2013 Jan;49(1):194-210. doi: 10.1016/j.ejca.2012.07.010 -> Abstract PubMed

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2012

von der Brelie C, Simon A, Gröner A, Molitor E, Simon M
Evaluation of an institutional guideline for the treatment of cerebrospinal fluid shunt-associated infections
Acta Neurochir (Wien). 2012 Sep;154(9):1691-7. doi: 10.1007/s00701-012-1329-x -> Abstract PubMed

David R, Braun Y, Stenzhorn H, Graf N
Der Einfluss des virtuellen Patienten auf das Design von klinischen Studien
In: Niederlag W, Lemke HU. Lehrach H, Peitgen HO: Der virtuelle Patient. Halth Academy, Dresden 2012 ISBN 978-3-00-040331-6; S. 171-181 -> Abstract

Sfakianakis S, Sakkalis V, Marias K, Stamatakos G, McKeever S, Deisboeck TS, Graf N
An architecture for integrating cancer model repositories
Conf Proc IEEE Eng Med Biol Soc. 2012 Aug;2012:6628-31. doi: 10.1109/EMBC.2012.6347514 -> Abstract PubMed

David R, Graf N, Karatzanis I, Stenzhorn H, Manikis GC, Sakkalis V, Stamatakos GS, Marias K
Clinical Evaluation of DoctorEye Platform in Nephroblastoma
In G. Stamatakos and D. Dionysiou (Eds): Proc. 2012 5th Int. Adv. Res. Workshop on In Silico Oncology and Cancer Investigation – The TUMOR Project Workshop (IARWISOCI), Athens, Greece, Oct.22-23, 2012, pp.35-38. ISBN: 978-618-80348-0-8 -> Open-Access Proceedings

Georgiadi EC, Dionysiou DD, Graf N, Stamatakos GS
Modeling Nephroblastoma Treatment Response Cases with In-Silico Scenarios
In G. Stamatakos and D. Dionysiou (Eds): Proc. 2012 5th Int. Adv. Res. Workshop on In Silico Oncology and Cancer Investigation – The TUMOR Project Workshop (IARWISOCI), Athens, Greece, Oct.22-23, 2012, pp.39-42. ISBN: 978-618-80348-0-8 -> Open-Access Proceedings

Verschuur A, Van Tinteren H, Graf N, Bergeron C, Sandstedt B, de Kraker J
Treatment of pulmonary metastases in children with stage IV nephroblastoma with risk-based use of pulmonary radiotherapy
J Clin Oncol. 2012 Oct 1;30(28):3533-9 -> Abstract PubMed

Gooskens SL, Furtwängler R, Vujanic GM, Dome JS, Graf N, van den Heuvel-Eibrink MM
Clear cell sarcoma of the kidney: a review
Eur J Cancer. 2012 Sep;48(14):2219-26. doi: 10.1016/j.ejca.2012.04.009 -> Abstract PubMed

Graf N, van Tinteren H, Bergeron C, Pein F, van den Heuvel-Eibrink MM, Sandstedt B, Schenk JP, Godzinski J, Oldenburger F, Furtwängler R, de Kraker J
Characteristics and outcome of stage II and III non-anaplastic Wilms' tumour treated according to the SIOP trial and study 93-01
Eur J Cancer. 2012 Nov;48(17):3240-8. doi: 10.1016/j.ejca.2012.06.007 -> Abstract PubMed

Schmitt J, Backes C, Nourkami-Tutdibi N, Leidinger P, Deutscher S, Beier M, Gessler M, Graf N, Lenhof HP, Keller A, Meese E
Treatment-independent miRNA signature in blood of wilms tumor patients
BMC Genomics 2012, 13:379 doi:10.1186/1471-2164-13-379 -> Full Paper

Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber UD, Wang Q, Lasitschka B, Bartholomae CC, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts MJ, Russell RB, Coco S, Paolo Tonini G, Schüller U, Hans V, Graf N, Kim YJ, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann MU, Frühwald MC, Hasselblatt M, Jabado N, Rutkowski S, von Bueren AO, Williamson D, Clifford SC, McCabe MG, Peter Collins V, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott PA, Taylor MD, Meyerson M, Pomeroy SL, Yaspo ML, Korbel JO, Korshunov A, Eils R, Pfister SM, Lichter P
Dissecting the genomic complexity underlying medulloblastoma
Nature. 2012 Jul 25. doi: 10.1038/nature11284 -> Abstract PubMed

Schmitt J, Heisel S, Keller A, Leidinger P, Ludwig N, Habel N, Furtwängler R, Nourkami-Tutdibi N, Wegert J, Grundy P, Gessler M, Graf N, Lenhof HP, Meese E
Multicenter study identified molecular blood-born protein signatures for Wilms Tumor
Int J Cancer. 2012 Aug 1;131(3):673-82. doi: 10.1002/ijc.26419 -> Abstract PubMed

Marias K, Sakkalis V, Graf N
A Framework for Multimodal Imaging Biomarker Extraction with Application to Brain MRI
Data Mining for Biomarker Discovery, Springer Optimization and Its Applications, 2012, Volume 65, 91-116, DOI: 10.1007/978-1-4614-2107-8_6  -> Full Paper

Graf N, Muntean W, Sutor A
Hämatologische und onkologische Erkrankungen
Pädiatrie: 304 Tabellen. - 4., vollst. überarb. und erw. Aufl. - Stuttgart: Thieme, 2012. - (Duale Reihe), S. 429-514

Szavay P, Fuchs J, Leuschner I, Selle B, Graf N
Nierentumoren
Solide Tumoren im Kindesalter: Grundlagen - Diagnostik - Therapie. - Stuttgart: Schattauer, 2012, S. 111-140

Spreafico F, Graf N
Rare tumors of the urinary tract
Rare tumors in children and adolescents. - Berlin [u.a.]: Springer, 2012, S. 403-419

Graf N, Bergeron C
Wilms and other renal tumours
Cancer in children: clinical management. - 6. ed. - Oxford [u.a.]: Oxford University Press, 2012, S. 312-327

Girisch W, Willhelm C, Gottschling S, Gortner L, Meyer S
Role of Cochrane reviews in pediatric neurology
Pediatr Neurol. 2012 Feb;46(2):63-9 -> Abstract PubMed

Sander J, Shamdeen MG, Gottschling S, Gortner L, Gräber S, Meyer S
Melatonin does not influence sleep deprivation electroencephalogram recordings in children
Eur J Pediatr. 2012 Apr;171(4):675-9 -> Abstract PubMed

Maojo V, Fritts M, Martin-Sanchez F, Iglesia D, Cachau RE, Garcia-Remesal M, Crespo J, Mitchell JA, Anguita A, Baker N, Barreiro JM, Benitez SE, Calle G, Facelli JC, Ghazal P, Geissbuhler A, Gonzalez-Nilo F, Graf N, Grangeat P, Hermosilla I, Hussein R, Kern J, Koch S, Legre Y, Lopez-Alonso V, Lopez-Campos G, Milanesi L, Moustakis V, Munteanu C, Otero P, Pazos A, Perez-Rey D, Potamias G, Sanz F, Kulikowski C
Nanoinformatics: developing new computing applications for nanomedicine
Computing, Volume 94, Number 6 (2012), 521-539, DOI: 10.1007/s00607-012-0191-2 -> Full Paper

Simon A, Müllenborn E, Prelog M, Schenk W, Holzapfel J, Ebinger F, Klabunde-Cherwon A, Faber J, Groll AH, Masjosthusmann K, Dohna-Schwake C, Beutel K, Dirkwinkel E, Lehrnbecher T, Ammann RA, Müller A.
Use of linezolid in neonatal and pediatric inpatient facilities-results of a retrospective multicenter survey
Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1435-42 -> Abstract PubMed

Warmann SW, Nourkami N, Frühwald M, Leuschner I, Schenk JP, Fuchs J, Graf N
Primary Lung Metastases in Pediatric Malignant Non-Wilms Renal Tumors: Data from SIOP 93-01/GPOH and SIOP 2001/GPOH
Klin Padiatr. 2012 Apr;224(3):148-152 -> Abstract PubMed

Grunewald TG, Greulich N, Kontny U, Frühwald M, Rutkowski S, Kordes U, Scheurlen W, Schmidt W, Stachel D, Metzler M, Mittler U, Graf N, Benesch M, Burdach S
Targeted Therapeutics in Treatment of Children and Young Adults with Solid Tumors: an Expert Survey and Review of the Literature
Klin Padiatr. 2012 Apr;224(3):124-131 -> Abstract PubMed

Wegert J, Bausenwein S, Roth S, Graf N, Geissinger E, Gessler M
Characterization of primary Wilms tumor cultures as an in vitro model
Genes Chromosomes Cancer. 2012 Jan;51(1):92-104. doi: 10.1002/gcc.20936 -> Abstract PubMed

Smets AM, Tinteren Hv, Bergeron C, Camargo BD, Graf N, Pritchard-Jones K, Kraker Jd
The contribution of chest CT-scan at diagnosis in children with unilateral Wilms' tumour. Results of the SIOP 2001 study
Eur J Cancer. 2012 May;48(7):1060-5 -> Abstract PubMed

Beck T, Gollapudi S, Brunak S, Graf N, Lemke HU, Dash D, Buchan I, Díaz C, Sanz F, Brookes AJ
Knowledge engineering for health: A new discipline required to bridge the "ICT gap" between research and healthcare
Hum Mutat. 2012 May;33(5):797-802. doi: 10.1002/humu.22066 -> Abstract PubMed

Schmid I, Häberle B, Albert MH, Corbacioglu S, Fröhlich B, Graf N, Kammer B, Kontny U, Leuschner I, Scheel-Walter HG, Scheurlen W, Werner S, Wiesel T, von Schweinitz D
Sorafenib and cisplatin/doxorubicin (PLADO) in pediatric hepatocellular carcinoma
Pediatr Blood Cancer. 2012 Apr;58(4):539-44. doi: 10.1002/pbc.23295 -> Abstract PubMed

Biglari B, Moghaddam A, Santos K, Blaser G, Büchler A, Jansen G, Längler A, Graf N, Weiler U, Licht V, Strölin A, Keck B, Lauf V, Bode U, Swing T, Hanano R, Schwarz NT, Simon A.
Multicentre prospective observational study on professional wound care using honey (Medihoney™)
Int Wound J. 2012 Apr 11. doi: 10.1111/j.1742-481X.2012.00970.x -> Abstract PubMed

O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, Argani P, Han JS, Karlsson J, Gisselson D, Leuschner I, Gessler M, Graf N, Fletcher JA, O'Sullivan MJ
Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney
J Pathol. 2012 May;227(1):72-80. doi: 10.1002/path.3985 -> Abstract PubMed

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2011

Pritchard-Jones K, Graf N, Bergeron C, de Camargo B, van den Heuvel-Eibrink M, Sandstedt B, Godzinski J, Oldenburger F, van Tinteren H, de Kraker J
Doxorubicin can be safely omitted from the treatment of stage II/III, intermediate risk histology Wilms tumour : results of the SIOP WT 2001 randomised trial, on behalf of the SIOP Renal Tumours Study Group
Abstract book / 2011 European Multidisciplinary Cancer Congress. - Amsterdam [u.a.] : Elsevier, 2011. - (European journal of cancer ; 47, Suppl. 1), S. S284-S285 -> Full Paper

Graf N, van Tinteren H, Pritchard-Jones K, Bergeron C, Sandstedt B, Leuschner I, Vujanic G, Boccon-Gibod L, van den Heuvel-Eibrink, M, de Camargo B, Spreafico F, Oldenburger F, Godzinski J, de Kraker J
Is the absolute blastema volume after preoperative chemotherapy in nephroblastoma relevant for prognosis?
Pediatric blood & cancer. - 57. 2011, 5, S. 741-742

Slotta JE, Heine S, Kauffels A, Krenn T, Grünhage F, Wagner M, Graf N, Schilling MK, Schuld J
Gastrectomy with isoperistaltic jejunal parallel pouch in a 15-year-old adolescent boy with gastric adenocarcinoma and autosomal recessive agammaglobulinemia
J Pediatr Surg. 2011 Sep;46(9):e21-4 -> Abstract PubMed

Meyer S, Gottschling S, Gortner L
Heavy alcohol consumption in children and adolescents: characteristics and gender differences
Eur J Pediatr. 2011 Jul;170(7):951-2; author reply 953-4 -> Abstract PubMed

Meyer S, McGuire W, Gottschling S, Mohammed Shamdeen G, Gortner L
The role of vasopressin and terlipressin in catecholamine-resistant shock and cardio-circulatory arrest in children: review of the literature
Wien Med Wochenschr. 2011 Apr;161(7-8):192-203 -> Abstract PubMed

Meyer S, Shamdeen MG, Gottschling S, Strittmatter M, Gortner L
Sudden unexpected death in epilepsy in children
J Paediatr Child Health. 2011 Jun;47(6):326-31. doi: 10.1111/j.1440-1754.2010.01734.x -> Abstract PubMed

Zasada SJ, Wang T, Haidar A, Liu E, Graf N, Clapworthy G, Manos S, Coveney PV
IMENSE: An e-infrastructure environment for patient specific multiscale data integration, modelling and clinical treatment
J Computational Science, 2011, dx.doi.org/10.1016/j.jocs.2011.07.001 -> Full Paper

Marias K, Dionysiou D, Sakkalis V, Graf N, Bohle R, Coveney PV, Wan S, Folarin A, Büchler P, Reyes M, Clapworthy G, Liu E, Sabczynski J, Bily T, Roniotis A, Tsiknakis M, Kolokotroni E, Giatili S, Veith C, Messe E, Stenzhorn H, Yoo-Jin Kim, Zasada S, Haidar A, May C, Bauer S, Wang T, Zhao Y, Karasek M, Grewer R, Franz A, Stamatakos G
Clinically-Driven Design of Multiscale Cancer Models: the Contra Cancrum Project Paradigm
Interface Focus 1:450-461, 2011 -> Full Paper

Schmitt J, Keller A, Nourkami-Tutdibi N, Heisel S, Habel N, Leidinger P, Ludwig N, Gessler M, Graf N, Berthold F, Lenhof HP, Meese E
Autoantibody signature differentiates Wilms tumor patients from neuroblastoma patients
PLoS One. 2011;6(12):e28951 -> Abstract PubMed

Moser O, Lück, S, Dilloo D, Eis-Hübinger AM, Simon A
Sapovirus as a gastrointestinal pathogen in febrile paediatric patients with cancer
J. Med. Virol. 83:2233–2236, 2011 -> Full Paper

Krenn T, Fleischhack G, Moser O, Dilloo D, Bode U, Gräber S, Furtwängler R, Graf N, Simon A
Bloodstream Infections in Paediatric Cancer Patients. Prospective Comparative Study in 2 University Hospitals
Klin Padiatr. 2011 Nov;223(6):335-340 -> Abstract PubMed

Manakis GC, Emmanouilidou D, Sakkalis V, Graf N, Marias K
A fully automated image analysis framework for quantitative assessment of temporal tumor changes
Proceedings of the 3rd International Conference on E-Health and Bioengineering - EHB 2011, 24th - 26th November 2011, Iasi, Romania

Wegert J, Bausenwein S, Kneitz S, Roth S, Graf N, Geissinger E, Gessler M.
Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro
Mol Cancer. 2011 Nov 8;10(1):136 -> Abstract PubMed

Pfaff E, Remke M, Sturm D, Benner A, Witt H, Milde T, von Bueren AO, Jorch N, Graf N, Kulozik AE, Witt O, Scheurlen W, von Deimling A, Rutkowski S, Taylor MD, Tabori U, Lichter P, Korshunov A, Pfister SM
Reply to J.C. Lindsey et al.
JCO 29:e348-e349, 2011 -> Download

Godzinski J, van Tinteren H, de Kraker J, Graf N, Bergeron C, Heij H, von Schweinitz D, Fuchs J, Cecchetto G, Audry G, Gauthier F, Sandstedt B; on behalf of the SIOP Nephroblastoma Trial & Study Committee.
Nephroblastoma: does the decrease in tumor volume under preoperative chemotherapy predict the lymph nodes status at surgery?
Pediatr Blood Cancer. 2011 Apr 29. doi: 10.1002/pbc.23147 -> Abstract PubMed

Heine S, Fuchs A, von Müller L, Krenn T, Nemat S, Graf N, Simon A
Legionellosis must be kept in mind in case of pneumonia with lung abscesses in children receiving therapeutic steroids
Infection. 2011 Oct;39(5):481-4. Epub 2011 Jun 29 -> Abstract PubMed

Keller A, Leidinger P, Bauer A, Elsharawy A, Haas J, Backes C, Wendschlag A, Giese N, Tjaden C, Ott K, Werner J, Hackert T, Ruprecht K, Huwer H, Huebers J, Jacobs G, Rosenstiel P, Dommisch H, Schaefer A, Müller-Quernheim J, Wullich B, Keck B, Graf N, Reichrath J, Vogel B, Nebel A, Jager SU, Staehler P, Amarantos I, Boisguerin V, Staehler C, Beier M, Scheffler M, Büchler MW, Wischhusen J, Haeusler SF, Dietl J, Hofmann S, Lenhof HP, Schreiber S, Katus HA, Rottbauer W, Meder B, Hoheisel JD, Franke A, Meese E
Toward the blood-borne miRNome of human diseases
Nat Methods. 2011 Sep 4;8(10):841-3. doi: 10.1038/nmeth.1682 -> Abstract PubMed

Alkassar M, Gärtner B, Roemer K, Graesser F, Rommelaere J, Kaestner L, Haeckel I, Graf N
The combined effects of oncolytic reovirus plus Newcastle disease virus and reovirus plus parvovirus on U87 and U373 cells in vitro and in vivo
J Neurooncol. 2011 Sep;104(3):715-27. Epub 2011 May 24 -> Abstract PubMed

Martin L, Anguita A, Graf N, Tsiknakis M, Brochhausen M, Rüping S, Bucur A, Sfakianakis S, Sengstag T, Buffa F, Stenzhorn H
ACGT: Advancing Clinico-genomic trials on cancer - Four years of experience
Stud Health Technol Inform. 2011;169:734-8 -> Abstract PubMed

Segers H, van den Heuvel-Eibrink MM, Pritchard-Jones K, Coppes MJ, Aitchison M, Bergeron C, de Camargo B, Dome JS, Grundy P, Gatta G, Graf N, Grundy P, Kalapurakal JA, de Kraker J, Perlman EJ, Reinhard H, Spreafico F, Vujanic G, Warwick AB; SIOP-RTSG and the COG-Renal Tumour Committee
Management of adults with Wilms' tumor: recommendations based on international consensus
Expert Rev Anticancer Ther. 2011 Jul;11(7):1105-13 -> Abstract PubMed

Rossi S, Christ-Neumann ML, Rüping S, Buffa FM, Wegener D, McVie G, Coveney PV, Graf N, Delorenzi M
p-Medicine: From data sharing and integration via VPH models to personalized medicine
ecancer 2011, 5:218 DOI: 10.3332/ecancer.2011.218 -> Download

Brochhausen M, Spear AD, Cocos C, Weiler G, Martín L, Anguita A, Stenzhorn H, Daskalaki E, Schera F, Schwarz U, Sfakianakis S, Kiefer S, Dörr M, Graf N, Tsiknakis M
The ACGT Master Ontology and its applications - towards an ontology-driven cancer research and management system
J Biomed Inform. 2011 Feb;44(1):8-25 -> Abstract PubMed

Furtwängler R, Nourkami N, Alkassar M, von Schweinitz D, Schenk JP, Rübe C, Siemer S, Leuschner I, Graf N
Update on relapses in unilateral nephroblastoma registered in 3 consecutive SIOP/GPOH studies - a report from the GPOH-nephroblastoma study group
Klin Padiatr. 2011 May;223(3):113-9 -> Abstract PubMed

Royer-Pokora B, Graf N
Wilms Tumors Arising at Young Age: a Genetic Basis to Distinguish Subgroups for Individualized Therapy
J Clin Oncol. 2011 Jun 1;29(16):e485-6; author reply e487-8 -> Abstract PubMed

Warmann SW, Furtwängler R, Blumenstock G, Armeanu S, Nourkami N, Leuschner I, Schenk JP, Graf N, Fuchs J
Tumor Biology Influences the Prognosis of Nephroblastoma Patients With Primary Pulmonary Metastases: Results From SIOP 93-01/GPOH and SIOP 2001/GPOH
Ann Surg. 2011 Jul;254(1):155-62 -> Abstract PubMed

Alloussi SH, Alkassar M, Urbschat S, Graf N, Gärtner B
All reovirus subtypes show an oncolytic potential in primary cell culture of human high-grade glioma
Oncol Rep. 2011 Sep;26(3):645-9. doi: 10.3892/or.2011.1331 -> Abstract PubMed

Benesch M, Leuschner I, Wardelmann E, Thielen M, Schmid I, Kontny U, Ebetsberger G, Frey E, Graf N, Schneider DT, Kremens B, Amann G, Urban C, Schlemmer M, Quehenberger F, Klingebiel T, Dantonello T, Koscielniak E
Gastrointestinal stromal tumours in children and young adults: A clinicopathologic series with long-term follow-up from the database of the Cooperative Weichteilsarkom Studiengruppe (CWS)
Eur J Cancer. 2011 Jul;47(11):1692-8 -> Abstract PubMed

van den Heuvel-Eibrink MM, van Tinteren H, Rehorst H, Coulombe A, Patte C, de Camargo B, de Kraker J, Leuschner I, Lugtenberg R, Pritchard-Jones K, Sandstedt B, Spreafico F, Graf N, Vujanic GM
Malignant rhabdoid tumours of the kidney (MRTKs), registered on recent SIOP protocols from 1993 to 2005: A report of the SIOP renal tumour study group
Pediatr Blood Cancer. 2011 May;56(5):733-7 -> Abstract PubMed

Stamatakos GS, Georgiadi EC, Graf N,Kolokotroni EA, Dionysiou DD
Exploiting Clinical Trial Data Drastically Narrows the Window of Possible Solutions to the Problem of Clinical Adaptation of a Multiscale Cancer Model
PLoS ONE 6(3) -> Full Paper

Fisch UP, Zehnder A, Hirt A, Niggli F, Simon A, Ozsahin H, Schlapbach LJ, Ammann RA
Serum concentrations of mannan-binding lectin (MBL) and MBL-associated serine protease-2 are higher in children with cancer than in healthy controls
Swiss Medical Weekly 2011 Mar 16

Ludwig N, Keller A, Heisel S, Leidinger P, Rheinheimer S, Andres C, Stephan B, Steudel WI, Donauer E, Graf N, Burgeth B, Weickert J, Lenhof HP, Meese E
Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%y
Int J Cancer. 2011 Mar 15;128(6):1493-5016 -> Abstract PubMed

Agyeman P, Aebi C, Hirt A, Niggli F, Nadal D, Simon A, Ozsahin H, Kontny U, Kuhne T, Beck Popovic M, Leibundgut K, Bodmer N, Ammann RA
Predicting Bacteremia in Febrile Children with Cancer and Chemotherapy-Induced Neutropenia. Results of the Prospective Multicenter SPOG 2003 FN Study
Peditatr Infect Dis J 2011 Mar 9 -> Abstract PubMed

von Bueren AO, Warmuth-Metz M, Schlegel PG, Soerensen N, Krauss J, Roggendorf W, Pietsch T, Feiden W, Graf N, Pohl F, Flentje M, Kuehl J, Rutkowski S
Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses
Pediatr Blood Cancer. 2011 Mar;56(3):503-5 -> Abstract PubMed

Linden K, Moser O, Simon A, Eis-Hubinger AM, Fleischhack G, Born M, Tschampa H, Rosenbaum T, Koster B, Lentze M
Transient splenial lesion in influenza A(H1N1) 2009 infection
Radiologe 2011 (E Pub 18.02.2011)

von Hornstein S, Kortmann RD, Pietsch T, Emser A, Warmuth-Metz M, Soerensen N, Straeter R, Graf N, Thieme B, Gnekow AK
Impact of chemotherapy on disseminated low-grade glioma in children and adolescents: Report from the HIT-LGG 1996 trial
Pediatr Blood Cancer. 2011 Feb 11 -> Abstract PubMed

Heinrich N, Mueller A, Bartmann P, Simon A, Bierbaum G, Engelhart S
Successful management of an MRSA outbreak in a neonatal intensive care unit
Eur J Clin Microbiol Infect Dis 2011 -> Abstract PubMed

Paulides M, Stöhr W, Laws HJ, Graf N, Lakomek M, Berthold F, Schmitt K, Niggli F, Jürgens H, Bielack S, Koscielniak E, Klingebiel T, Langer T
Antibody levels against tetanus and diphtheria after polychemotherapy for childhood sarcoma: A report from the Late Effects Surveillance System
Vaccine. 2011 Jan 7 -> Abstract PubMed

Graf N
In silico oncology. - Part II : Clinical requirements regarding in silico oncology
In: Hrsg.: Deisboeck, Thomas S. ; Stamatakos, Georgios S.: Multiscale cancer modeling. - Boca Raton, Fla. : CRC ; London : Taylor & Francis, 2011. - (Chapman & Hall/CRC mathematical and computational biology series ; 34) , S. 437-446

Simon A, Nowak H, Sterz R
Use of Palivizumab in Germany: Data from 2002-2007
Klin Padiatr. 2011 Sep;223(5):292-8 -> Abstract PubMed

Exner M, Engelhart S, Gebel J, Ilschner C, Pfeifer R, Höller C, Dilloo D, Maschmeyer G, Simon A
Hygiene-Tipps für immunsupprimierte Patienten zur Vermeidung übertragbarer Infektionskrankheiten
Hygiene & Medizin; 2011, 36 (1/2) : 36-44

Simon A, Exner M, Engelhart S, Wischnewski N
Umgang mit haMRSA kolonisierten Kindern und Jugendlichen im ambulanten Betreuungsumfeld
Hygiene & Medizin 2011; 36 [1/2]: 30–35

Simon A, Tutdibi E, von Müller L, Gortner L
Beatmungs-assoziierte Pneumonie bei Kindern
Monatsschr Kinderheilkd 2011; 159 (3)224–232 -> Full Paper

Simon A, Prusseit J, Muller A
Respiratory syncytial virus infection in children with neuromuscular impairment
Open Microbiol J 2011;5:155-8 -> Full Paper

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2010

Pfaff E, Remke M, Sturm D, Benner A, Witt H, Milde T, von Bueren AO, Wittmann A, Schöttler A, Jorch N, Graf N, Kulozik AE, Witt O, Scheurlen W, von Deimling A, Rutkowski S, Taylor MD, Tabori U, Lichter P, Korshunov A, Pfister SM

TP53 Mutation Is Frequently Associated With CTNNB1 Mutation or MYCN Amplification and Is Compatible With Long-Term Survival in Medulloblastoma
J Clin Oncol. 2010 Nov 8. [Epub ahead of print] -> Abstract PubMed

Estlin EJ, Graf N
Renal Tumors
In: Hrsg.: Estlin, Edward J. ; Gilbertson, Richard J. ; Wynn, Robert: Pediatric hematology and oncology : scientific principles and clinical practice. - Chichester [u.a.] : Wiley-Blackwell, 2010, S. 193-215

Giebel SM, Schiltz JP, Graf N,Schenk JP
Shape analysis of retroperitoneal tumors in childhood in magnetic resonance imaging
Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg / Numéro spécial. - 2010, 1, S. 41-51

Stenzhorn H, Weiler G, Brochhausen M, Schera F, Kritsotakis V, Tsiknakis M, Kiefer S, Graf N
The ObTiMA system - ontology-based managing of clinical trials
Stud Health Technol Inform. 2010;160(Pt 2):1090-4 -> Abstract PubMed

Müller CSL, Tilgen W, Pföhler C, Graf N
Cutaneous and systemic metastasis of a testicular choriocarcinoma
Am J Dermatopathol. 2010 32:521-522 -> Abstract PubMed

Skounakis E, Farmaki Ch, Sakkalis V, Roniotis A, Banitsas K, Graf N, Marias K
DoctorEye: A clinically driven multifunctional platform, for accurate processing of tumors in medical images
The open Medical Informatics Journal. 2010 4:105-115

Wolff JE, Mohiuddin K, Jorch N, Graf N, Wagner S, Vats T, Gnekow A
Measuring performance status in pediatric patients with brain tumors--experience of the HIT-GBM-C protocol
Pediatr Blood Cancer. 2010 Sep;55(3):520-4 -> Abstract PubMed

Farmaki C, Marias K, Sakkalis V, Graf N
Spatially adaptive active contours: a semi-automatic tumor segmentation framework
Int J Comput Assist Radiol Surg. 2010 Jul;5(4):369-84 -> Abstract PubMed

Oster I, Shamdeen GM, Gottschling S, Gortner L, Meyer S
Electroencephalogram in children with minor traumatic brain injury
J Paediatr Child Health. 2010 Jul;46(7-8):373-7 -> Abstract PubMed

Paulides M, Stöhr W, Laws HJ, Graf N, Lakomek M, Berthold F, Schmitt K, Niggli F, Jürgens H, Bielack S, Koscielniak E, Klingebiel T, Langer T
Immunity against tetanus and diphtheria after childhood sarcoma treatment
Klin Padiatr. 2010 May;222(3):196 -> Abstract PubMed

Brochhausen M, Slaughter L, Stenzhorn H, Graf N
User specific perspectives on ontologies
Stud Health Technol Inform. 2010; 156:114-21 -> Abstract PubMed

Graf N
Glioblastoma in children with NF1: the need for basic research
Pediatr Blood Cancer. Jul 1;54(7):870-1, 2010 -> Abstract PubMed

Fischer U, Leidinger P, Keller A, Folarin A, Ketter R, Graf N, Lenhof HP, Meese E
Amplicons on chromosome 12q13-21 in glioblastoma recurrences
Int J Cancer. Jun 1;126(11):2594-602, 2010 -> Abstract PubMed

Williams RD, Al-Saadi R, Chagtai T, Popov S, Messahel B, Sebire N, Gessler M, Wegert J, Graf N, Leuschner I, Hubank M, Jones C, Vujanic G, Pritchard-Jones K; Children's Cancer and Leukaemia Group; SIOP Wilms' Tumour Biology Group
Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms' tumor
Clin Cancer Res. Apr 1;16(7):2036-45, 2010 -> Abstract PubMed

Kordes U, Gesk S, Frühwald MC, Graf N, Leuschner I, Hasselblatt M, Jeibmann A, Oyen F, Peters O, Pietsch T, Siebert R, Schneppenheim R
Clinical and molecular features in patients with atypical teratoid rhabdoid tumor or malignant rhabdoid tumor
Genes Chromosomes Cancer 49:176-181, 2010 -> Abstract PubMed

Rübe CE, Fricke A, Schneider R, Simon K, Kühne M, Fleckenstein J, Gräber S, Graf N, Rübe C
DNA Repair Alterations in Children with Pediatric Malignancies: Novel Opportunities to Identify Patients at Risk for High-Grade Toxicities
Int J Radiat Oncol Biol Phys Feb 10, 2010 -> Abstract PubMed

Meyer S, Shamdeen MG, Furtwängler R, Gottschling S, Gortner L
A floppy neonate with respiratory failure and burst suppression EEG (case presentation)
Acta Paediatr. Mar;99(3):326-7, 474-5, 2010 -> Abstract PubMed

Meyer S, Sander J, Gräber S, Gottschling S, Gortner L
Agreement of invasive versus non-invasive blood pressure in preterm neonates is not dependent on birth weight or gestational age
J Paediatr Child Health. 2010 May;46(5):249-54 -> Abstract PubMed

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2009

Spreafico F, Pritchard Jones K, Malogolowkin MH, Bergeron C, Hale J, de Kraker J, Dallorso S, Acha T, de Camargo B, Dome JS, Graf N
Treatment of relapsed Wilms tumors: lessons learned
Expert Rev Anticancer Ther 12:1807-15, 2009 -> Abstract PubMed

Graf N, Nourkami N, Furtwängler R
Nierentumoren bei Kindern und Jugendlichen
TumorDiagnostik & Therapie 30:186-191, 2009

Meyer S, Gortner L, Gottschling S, Gärtner B, Abdul-Khaliq H
Cardiogenic shock in a neonate with enterovirus myocarditis
Klin Padiatr. 2009 Dec; 221(7): 444-7 -> Abstract PubMed

Meyer S, Gottschling S, Gortner L
The prognosis of children with cancer in the PICU
J Pediatr Hematol Oncol. 2009 Dec;31(12): 990-1

Gunter Assmann, Christian Werner, Markus Herrmann, Dunja Momber, Thomas Krenn, Lothschütz Daniela, Lars Fischer, Hess S, Ralf Ketter, Wolfgang Feiden, Stefan Jung, Wolfgang Herrmann, Schubert J, Michael Pfreundschuh and Thomas Widmann
Detection of meningeosis neoplastica by Real-Time Quantitation of Telomerase activity
Clin Chem Lab 2009 Med 47:1271-1276 -> Abstract PubMed

Wegert J, Wittmann S, Leuschner I, Geissinger E, Graf N, Gessler M
WTX inactivation is a frequent, but late event in Wilms tumors without apparent clinical impact
Genes Chromosomes Cancer. 2009 Sep 16. -> Abstract PubMed

Meyer S, Lindinger A, Löffler G, Limbach HG, Shamdeen MG, Gottschling S, Reith W, Gortner L
Mechanisms of disease/hypothesis: neurogenic left ventricular dysfunction and neurogenic pulmonary oedema
Wien Med Wochenschr. 2009;159(13-14):342-5 -> Abstract PubMed

Nourkami N, Furtwängler R, Alkassar M, Graf N; SIOP/GPOH Nephroblastoma Trials Group
Secondary neoplasms after Wilms' tumor in Germany.
Strahlenther Onkol. 2009 Aug;185 Suppl 2:11-2.

Spreafico F, Pritchard-Jones K, Bergeron C, de Kraker J, Dallorso S, Graf N
Value and difficulties of a common European strategy for recurrent Wilms' tumor.
Expert Rev Anticancer Ther. 2009 Jun;9(6):693-6.

Brecht IB, Graf N, Schweinitz D, Frühwald MC, Bielack SS, Schneider DT
Networking for children and adolescents with very rare tumors: foundation of the GPOH Pediatric Rare Tumor Group.
Klin Padiatr. 2009 May-Jun;221(3):181-5. -> Abstract PubMed

Alkassar M, Gottschling S, Krenn T, Graf N
Metastatic choriocarcinoma in a 17-year old boy.
Klin Padiatr. 2009 May-Jun;221(3):179.

Graf N, Hoppe A, Georgiadi E, Belleman R, Desmedt C, Dionysiou D, Erdt M, Jacques J, Kolokotroni E, Lunzer A, Tsiknakis M, Stamatakos G
'In silico' oncology for clinical decision making in the context of nephroblastoma.
Klin Padiatr. 2009 May-Jun;221(3):141-9. Epub 2009 May 12. -> Abstract PubMed

Fuchs J, Kienecker K, Furtwängler R, Warmann SW, Bürger D, Thürhoff JW, Hager J, Graf N
Surgical aspects in the treatment of patients with unilateral wilms tumor: a report from the SIOP 93-01/German Society of Pediatric Oncology and Hematology.
Ann Surg. 2009 Apr;249(4):666-71. -> Abstract PubMed

Shamdeen A, Meyer S, Gottschling S, Oehl-Jaschkowitz B, Gortner L, Shamdeen MG
Pallister-Killian Syndrome (PKS) as a Cause of Mental Retardation.
Klin Padiatr. 2009 Mar-Apr;221(2):97-9. -> Abstract PubMed

Rutkowski S, Gerber NU, von Hoff K, Gnekow A, Bode U, Graf N, Berthold F, Henze G, Wolff JEA, Warmuth-Metz M, Soerensen N, Emser A, Ottensmeier H, Deinlein F, Schlegel PG, Kortmann RD, Pietsch T, and Kuehl J? for the German Pediatric Brain Tumor Study Group
Treatment of early childhood Medulloblastoma by postoperative chemotherapy and deferred radiotherapy.
Neurooncology 11:201-210, 2009 -> Abstract PubMed

Igel C, Graf N, Hohenberg G
eLearning in der Medizin 2.0
GMS Med Inform Biom Epidemiol 5(1): 2009, Doc12 (20090225) DOI: 10.3205/mibe000091

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2008

Gottschling S, Reindl TK, Meyer S, Berrang J, Henze G, Graeber S, Ong MF, Graf N
Acupuncture to alleviate chemotherapy-induced nausea and vomiting in pediatric oncology - a randomized multicenter crossover pilot trial.
Klin Padiatr. 2008 Nov-Dec;220(6):365-70. -> Abstract PubMed

Landmann E, Oschlies I, Zimmermann M, Moser O, Graf N, Suttorp M, Greiner J, Reiter A
Secondary non-Hodgkin lymphoma (NHL) in children and adolescents after childhood cancer other than NHL.
Br J Haematol. 2008 Nov;143(3):387-94. -> Abstract PubMed

Gottschling S, Reinhard H, Pagenstecher C, Krueger S, Raedle J, Plotz G, Henn W, Buettner R, Meyer S, Graf N
Hypothesis: Possible role of retinoic acid therapy in patients with mismatch repair gene defects.
Eur J Ped 167:225-229, 2008 (IF:1.277, 2007) -> Abstract PubMed

Kaste SC, Dome JS, Babyn PS, Graf N, Grundy P, Godzinski J, Levitt GA, Jenkinson H
Wilms Tumor: Prognostic factors, Staging, Therapy and Late Effects
Ped Radiology 38:2-17, 2008 (IF: 0.991, 2007) -> Abstract PubMed

Reinhard H, Reinert J, Beier R, Furtwängler R, Alkassar M, Rutkowski S, Frühwald M, Koscielniak E, Leuschner I, Kaatsch P, Graf N
Rhabdoid tumors in children: Prognostic factors in 70 patients diagnosed in Germany.
Oncology Reports 19: 819-823, 2008 (IF: 1.597, 2007) -> Abstract PubMed

Graf N, Desmedt C, Buffa F, Kafetzopoulos D, Forgó N, Kollek R, Hoppe A, Stamatakos G, Tsiknakis M
Post-genomic clinical trials ? the perspective of ACGT.
Ecancermedicalscience 1: DOI: 10.3332/eCMS.2007.66, 2008

Reinhard H, Klingebiel T, Lang P, Bader P, Niethammer D, Graf N
Stem cell transplantation for polycythemia vera.
Pediatr Blood & Cancer 50:124-126, 2008 (IF: 2,164, 2007) -> Abstract PubMed

Wittmann S, Wunder C, Zirn B, Furtwängler R, Graf N, Gessler M
Wilms Tumors: New prognostic markers revealed by evaluation of genes correlated with clinical parameters in Wilms tumors.
Genes Chromosomes Cancer 47:386-395, 2008 (IF:4,532, 2007) -> Abstract PubMed

Fuchs J, Szavay P, Luithle T, Furtwangler R, Graf N
Surgical implications for liver metastases in nephroblastoma-Data from the SIOP/GPOH study.
Surg Oncol 17:33-40, 2008 (IF: 1.239, 2007) -> Abstract PubMed

Schenk JP, Graf N, Günther P, Ley S, Göppl M, Kulozik A, Rohrschneider WK, Tröger J.
Role of MRI in the management of patients with nephroblastoma.
Eur Radiol 18:683-691, 2008 (IF: 3.405, 2007) -> Abstract PubMed

van den Heuvel-Eibrink MM, Grundy P, Graf N, Pritchard-Jones K, Bergeron C, Patte C, Peter E, van Tinteren H, Rey A, Hutton C, Anderson JR, de Kraker J
Characteristics and Survival of 750 Children with a Renal Tumour in Infancy (0-6 months). A collaborative retrospective Study of the SIOP/GPOH/SFOP, NWTSG, and UK-CCSG.
Pediatr Blood & Cancer 50:1130-1134, 2008 (IF: 2.164, 2007) -> Abstract PubMed

Graf N, Hohenberg G, Igel C, Herrmann M
E-Learning in der Medizin. Nachfrageorientiert statt angebotsbasiert.
Dtsch Ärzteblatt 105:A1127-A1130, 2008

Graf N, Hohenberg G, Igel C, Sturm R
eLearning in der Medizin.
Saarländisches Ärzteblatt 61:8-9, 2008

Zils K, Furtwänler R, Reinhard H, Alkassar M, Graf N
Consultation within SIOP 2001/GPOH as part of the competence centre for nephroblastoma.
Klin Pädiatr 220:183-188, 2008 (IF: 1.321, 2007) -> Abstract PubMed

Wetli SC, Leuschner I, Harms D, Rufle A, Foerster A, Bihl M, Graf N, Furtwaengler R, Paulussen M, Briner J, Tornillo L, Mihatsch MJ, Zlobec I, Bruder E
KIT, PDGFRa and EGFR Analysis in Nephroblastoma.
Virchow Archiv 452:637-650, 2008 (IF:2.029; 2007) -> Abstract PubMed

Furtwängler R, Schenk JP, Alkassar M, Leuschner I, Rübe C, von Schweinitz D, Gessler M, Graf N
Das Nephroblastom und andere pädiatrische Nierentumoren.
Pädiat Prax 72:59-77, 2008 (IF:0; 2007)

Gottschling S, Meyer S, Gribova I, Distler L, Berrang J, Gortner L, Graf N, Shamdeen G
Laser acupuncture in children with chronic headache: a double-blind, randomized, bicenter, placebo-controlled trial.
Pain 137:405-412, 2008 (IF:5.249, 2007) -> Abstract PubMed

Reinhard H, Schmidt A, Furtwängler R, Leuschner I, Rübe C, von Schweinitz D, Zoubek A, Niggli F, Graf N
Outcome of relapses of nephroblastoma in patients registered in the SIOP/GPOH trials and studies.
Oncology Reports 20:463-467, 2008 (IF: 1.597, 2007) -> Abstract PubMed

Royer-Pokora B, Weirich A, Schumacher V, Uschkereit C, Beier M, Leuschner I, Graf N, Autschbach F, Schneider D, von Harrach M
Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein ß1 gene CTNNB1 for patients with Wilms tumors. Results of long-term surveillance of 71 patients from International Society of Pediatric Oncology Study 9/Society for Pediatric Oncology.
Cancer 113:1080-1089, 2008 (IF: 4.632, 2007) -> Abstract PubMed

Brochhausen M, Weiler G, Cocos C, Stenzhorn H, Graf N, Doerr M, Tsiknakis M
The ACGT Master Ontology on Cancer - a New Terminology Source for Oncological Practice, In: Puuronen S, Pechenizkiy M, Tsymbal A, Lee DJ (eds.): Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems.
IEEE Computer Society, Los Alamitos, pp324-329, 2008, DOI Bookmark: doi.ieeecomputersociety.org/10.1109/CBMS.2008.17 (IF: 1.597, 2007)

Kolokotroni EA, Stamatakos GS,  Dionysiou D, Georgiadi ECh, Desmedt C, Graf N
Translating Multiscale Cancer Models into Clinical Trials: Simulating Breast Cancer Tumor Dynamics within the Framework of the ?Trial of Principle? Clinical Trial and the ACGT Project.
Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering (BIBE 2008), Athens, Greece, 8-10 October 2008. IEEE Catalog Number: CFP08266, ISBN: 978-1-4244-2845-8, Library of Congress: 2008907441, Paper No. BE-2.1.1, length: 8 pages (in electronic format)

Georgiadi ECh, Kolokotroni EA, Dionysiou DD, Graf N, Hoppe A, Uzunoglu NK, Stamatakos GS
Simulating the response of Nephroblastoma Tumor to chemotherapy in the clinical context.
Proceedings of the 3rd International Advanced Research Workshop on In Silico Oncology, Istanbul, Turkey. Sept. 23-24, 2008: pp 27-30

Georgiadi ECh, Stamatakos GS, Graf N, Kolokotroni EA, Dionysiou DD, Hoppe A, Uzunoglu NK
Multilevel Cancer Modeling in the Clinical Environment: Simulating the Behavior of Wilms Tumor in the Context of the SIOP 2001/GPOH Clinical Trial and the ACGT Project.
Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering (BIBE 2008), Athens, Greece, 8-10 October 2008. IEEE Catalog Number: CFP08266, ISBN: 978-1-4244-2845-8, Library of Congress: 2008907441, Paper No. BE-2.1.2, length: 8 pages (in electronic format).

Brochhausen M, Weiler G, Martin L, Cocos C, Stenzhorn H, Graf N, Dörr M, Smith B, Tsiknakis M
Applications of the ACGT Master Ontology on Cancer.
In: R. Meersman, Z. Tari, P. Herrero (eds.): OTM 2008 Workshops, LNCS 5333, 2008, 1046-1055.

Rutkowski S, Gerber NU, von Hoff K, Gnekow A, Bode U, Graf N, Berthold F, Henze G, Wolff JEA, Warmuth-Metz M, Soerensen N, Emser A, Ottensmeier H, Deinlein F, Schlegel PG, Kortmann RD, Pietsch T, and Kuehl J? for the German Pediatric Brain Tumor Study Group
Treatment of early childhood Medulloblastoma by postoperative chemotherapy and deferred radiotherapy.
Neurooncology, 2008 accepted (IF: 5.806, 2007) -> Abstract PubMed

Creutzig U, Zimmermann M, Lehrnbecher T, Graf N, Hermann J, Niemeyer C, Reiter A, Ritter J, Dworzak M, Stary J, Reinhardt D für die AML-BFM Studiengruppe.
Update: Results of study AML-BFM 98 in children and adolescents with acute myeloid leukemia after a median follow-up time of five years.Studie AML-BFM 98 für Kinder und Jugendliche mit akuter myeloischer Leukämie: Update der Ergebnisse nach einer medianen Beobachtungszeit von fünf Jahren.
Klin. Pädiatrie, 2008, (IF: 1.321, 2007)

Fuchs J, Kienecker K, Furtwängler R, Bürger D, Thüroff JW, Hager J, Graf N
Surgical Aspects in the treatment of patients with unilateral Wilms´tumor ? a report by the SIOP 93-01/ German Society of Pediatric Oncology and Hematology
Ann Surg accepted 2008, (IF: 7.446, 2007) -> Abstract PubMed

Zils K, Furtwängler R, Reinhard H, Alkassar M, Graf N
Consultation within the nephroblastoma trial SIOP 2001/GPOH as part of the workload in the trial office.
Klin Padiatr. 2008 May-Jun;220(3):183-8. -> Abstract PubMed

Möricke A, Reiter A, Zimmermann M, Gadner H, Stanulla M, Dördelmann M, Löning L, Beier R, Ludwig WD, Ratei R, Harbott J, Boos J, Mann G, Niggli F, Feldges A, Henze G, Welte K, Beck JD, Klingebiel T, Niemeyer C, Zintl F, Bode U, Urban C, Wehinger H, Niethammer D, Riehm H, Schrappe M
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.
Blood. 2008 May 1;111(9):4477-89. -> Abstract PubMed

Längler A, Spix C, Seifert G, Gottschling S, Graf N, Kaatsch P
Complementary and Alternative Treatment Methods in Children with Cancer. A population based retrospective survey on the prevalence of use in Germany.
EJC 44:2233-2240, 2008 (IF: 4.454, 2007) -> Abstract PubMed

Landmann E, Oschlies I, Moser O, Zimmermann M, Graf N, Suttorp M, Greiner J, Reiter A on behalf of the Berlin-Frankfurt-Münster group
Secondary non-Hodgkin?s lymphoma (NHL) in children and adolescents after childhood cancer other than NHL.
Brit J Haematol, 2008 accepted (IF: 4.490, 2007) -> Abstract PubMed

Jäger J, Köllner V, Graf N
Der OSCE (Objective Structured Clinical Examination) Allgemeinmedizin: eine kompetente praktische Prüfung nach dem Blockpraktikum.
Z Allg Med 84:376-381, 2008 (IF: nicht gelistet, 2007)

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2007

Luithle T, Szavay P, Furtwängler R, Graf N, Fuchs J
Treatment of Cystic Nephroma and Cystic Partially Differentiated Nephroblastoma-A Report From the SIOP/GPOH Study Group
J Urol 177:294-296, 2007, (IF: 3.713, 2004) -> Abstract PubMed

Stamatakos GS, Dionysiou DD, Graf NM, Sofra NA, Desmedt C, Hoppe A, Uzunoglu NK, Tsiknakis M
The "Oncosimulator": a multilevel, clinically oriented simulation system of tumor growth and organism response to therapeutic schemes. Towards the clinical evaluation of in silico oncology.
Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6629-32. -> Abstract PubMed

Wittmann S, Zirn B, Alkassar M, Ambros P, Graf N, Gessler M
Loss of 11q and 16q in Wilms tumors is associated with anaplasia, tumor recurrence, and poor prognosis.
Genes Chromosomes Cancer 46:163-170, 2007, (IF: 4.276, 2004) -> Abstract PubMed

Romeike BFM, Yoo-Jin K, Steudel WI, Graf N
Diffuse high-grade gliomas as second malignant neoplasms after radio-chemotherapy for pediatric malignancies.
Childs Nervous System 23:185-193, 2007(IF: 0.896, 2003) -> Abstract PubMed

Reinhard H, Furtwängler R, Graf N
Wilms-Tumoren ? Update 2007.
Urologe 46:143-145, 2007 (IF: 0.471, 2005)

Reinhard H, Furtwängler R, Siemer S, Wullich B, Graf N
Wilms-Tumor bei Erwachsenen.
Urologe 46:748-753, 2007  (IF: 0.471, 2005)

Reinhard H, Peters I, Gottschling S, Ebell W, Graf N
Squamous Cell carcinoma of the tongue in a 13-year old girl with fanconi anemia.
J Ped Hematol Oncol 29:488-491, 2007 (IF: 1.282, 2005) -> Abstract PubMed

Stamatakos GS, Dionysiou DD, Graf N, Sofra NA, Desmedt C, Hoppe A, Uzunoglu NK, Tsiknakis M
"The ?Oncosimulator?: a multilevel, clinically oriented simulation system of tumor growth and response to therapeutic schemes. Towards clinical evaluation of in silico oncology."
Proceedings of the 29th Annual International Conference of the IEEE EMBS, Cité Internationale, Lyon, France, August 23-26, 2007, SuB07.1, S. 6628-6631; Conf Proc IEEE Eng Med Biol Soc. 2007;1:6628-16631 -> Abstract PubMed

Weiler G, Brochhausen M, Graf N, Hoppe A, Schera F, Kiefer S
Ontology Based Data Management Systems for post-genomic clinical Trials within an European Grid Infrastructure for Cancer Research.
Proceedings of the 29th Annual International Conference of the IEEE EMBS, Cité Internationale, Lyon, France, August 23-26, 2007, SuA11.4; Conf Proc IEEE Eng Med Biol Soc. 2007;1:6434-6437 -> Abstract PubMed

Tsiknakis M, Rueping S, Martin L, Sfakianakis S, Bucur A, Sengstag T, Brochhausen M, Pucaski J, Graf N
Developing a European Grid infrastructure for cancer research: vision, architecture, and services.
Ecancermedicalscience 1: DOI: 10.3332/eCMS.2007.56, 2007

Bruder E, Moch H, Ehrlich D, Eble J, Leuschner I, Harms D, Argani P, Ladanyi M, Briner J, Graf N, Selle B, Rufle A, Koesters R
Wnt Signaling Pathway Activity in Renal Cell Carcinoma in Young Patients.
Modern Pathology 20:1217-1229, 2007 (IF: 4.286, 2007) -> Abstract PubMed

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2006

Schenk JP, Schrader C, Zieger B, Furtwängler R, Leuschner I, Graf N, Tröger J
Referenzradiologie des Nephroblastoms: Diagnosegenauigkeit und Bedeutung für die präoperative Chemotherapie.
Fortschr Röntgenstr 178:38-45, 2006 (IF: 1.786, 2003)

Szavay P, Luithle T, Graf N, Furtwängler R, Fuchs J
Primary Hepatic Metastases in Nephroblastoma ? A Report of the SIOP/GPOH Study.
J Pediatr Surg 41:168-172, 2006 (IF:1.449, 2003) -> Abstract PubMed

Gottschling S, Schneider G, Meyer S, Reinhard H, Dill-Müller D, Graf N
Two infants with life-threatening diffuse neonatal hemangiomatosis treated with cyclophosphamide.
Pediatr Blood Cancer 46: 239-242, 2006 (IF: 1.737, 2003 [Medical and Pediatric Oncology]) -> Abstract PubMed

Zirn B, Hartmann O, Samans B, Krause M, Wittmann S, Mertens F, Graf N, Eilers M, Gessler M
Expression profiling of Wilms tumors reveals new candidate genes for different clinical parameters.
Int J Cancer: 118:1954?1962, 2006 (IF:4.700, 2005) -> Abstract PubMed

Gottschling S, Graf N, Meyer S, Reinhard H, Krenn T, Rohrer T
Intracranial germinoma: A rare but important differential diagnosis in children with growth retardation.
Acta Paediatr 95:302-305, 2006 (IF: 1.277, 2005) -> Abstract PubMed

Furtwängler R, Reinhard H, Leuschner I, Schenk JP, Göbel U, Claviez A, Kulozik A, Zoubek A, von Schweinitz D, Graf N for the GPOH Nephroblastoma study group
Mesoblastic Nephroma ? A report from the Gesellschaft für pädiatrische Onkologie und Hämatolgie (GPOH).
Cancer 106:2275-83, 2006  -> Abstract PubMed

Knaup P, Garde S, Merzweiler A, Graf N, Schilling F, Weber R, Haux R
Towards shared patient records: An Architecture for Using Routine Data for Nationwide Research.
Int J Med Informatics 75:191-200, 2006 (IF: 1.178, 2003) -> Abstract PubMed

Zirn B, Samans B, Pietsch T, Leuschner I, Eilers M, Graf N, Gessler M
Target genes of the Wnt/ß-catenin pathway in Wilms tumors.
Genes, Chromosomes & Cancer: 45:565-574, 2006.  (IF: 4.192, 2003) -> Abstract PubMed

Ko HS, Graf N, Brambs HJ, Debatin KM, Leuschner I, Tröger J, Schenk JP
A patient with hematuria and cystic renal mass: Answer.
Pediatr Nephrol: 21:326-327, 2006 (IF: 1.219, 2003) -> Abstract PubMed

Pastore G, Znaor A, Spreafico F, Graf N, Pritchard-Jones K, Steliarova-Foucher E
Malignant renal tumors incidence and survival in European children: Report from the Automated Childhood Cancer Information System project.
EJC 42:2103-2114, 2006 (IF: 3,706, 2005) -> Abstract PubMed

Gottschling S, Längler A, Tautz C, Graf N
Komplementäre und alternative Behandlungsmethoden in der Kinderonkologie.
Klin Pädiatr 218:157-164, 2006 (IF:1.036, 2005)

Gottschling S, Meyer S, Reinhard H, Furtwängler R, Klotz D, Graf N
Intra-individual propofol dosage variability in children undergoing repetitive procedural sedations.
Pediatric Hematology and Oncology 23:1-8, 2006 (IF:0.491, 2004) -> Abstract PubMed

Creutzig U, Zimmermann M, Lehrnbecher T, Graf N, Hermann J, Niemeyer Ch, Reiter A, Ritter J, Dworzak M, Stary J, Reinhardt D
Less toxicity by optimizing chemotherapy, but not by addition of Granulocyte Colony-Stimulating Factor in children and adolescents with Acute Myeloid Leukemia. Results of study AML-BFM 98.
JCO 24:4499-4506, 2006 (IF: 11,810, 2005) -> Abstract PubMed

Selle B, Furthwängler R, Graf N, Kaatsch P, Leuschner I
A population based study of renal cell carcinoma in children in Germany 1980-2005: More frequently localized tumors, underlying disorders and better survival compared to adult counterpart.
Cancer 107:2906-2914, 2006, (IF: 4.800, 2005) -> Abstract PubMed

Graf N, Hoppe A
What are the expectations of a Clinician from In Silico Oncology ?
Edts.: Kostas M, Stamatakos G: Proceedings: 2nd International Advanced Research Workshop on In Silico Oncology (IARWISO), Kolympari, Chania, Greece , 25th and 26th September 2006

Sofra N, Stamatakos G, Graf N, Uzunoglu N
A four dimensional simulation model of the in vivo response of nephroblastoma to vincristine.
Edts.: Kostas M, Stamatakos G: Proceedings: 2nd International Advanced Research Workshop on In Silico Oncology (IARWISO), Kolympari, Chania, Greece , 25th and 26th September 2006

Wagner S, Monika Warmuth-Metz M, Gnekow A, Emser A, Sträter R, Rutkowski S, Jorch N, Schmid HJ, Berthold F,  Graf N, Kortmann RD, Pietsch T, Peters O, Sörensen N, Wolff JEA
Treatment Options in Childhood Pontine Gliomas.
J Neuro-Oncology 79:281-287, 2006 (IF: 1.568, 2003) -> Abstract PubMed

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2005

Wössmann W, Seidemann K, Mann G, Zimmermann M, Burkhardt B, Oschlies I, Ludwig WD, Klingebiel T, Graf N, Gruhn , Jürgens H, Niggli F, Parwaresch R, Gadner H, Riehm HJ, Schrappe M, Reiter A for the BFM Group
Administration schedule of high-dose Methotrexate influences outcome in children and adolescents with B-cell neoplasms. Results from trial NHL-BFM-95.
Blood 105:948-958, 2005  (IF: 10,120, 2003)

Schenk JP, Engelmann D, Zieger B, Semler O, Furtwängler R, Graf N, Tröger J
Bildgebende Differenzierung des Rhabdoidtumors vom Nephroblastom und mesoblastischen Nephrom.
Urologe [A] 44:155-161, 2005  (IF: 0.762, 2003)

Zirn B, Wittmann S, Graf N, Gessler M
Chibby, a novel antagonist of the Wnt pathway, is not involved in Wilms tumor development
Cancer letters, 220:115-120, 2005  (IF: 2.614, 2003) -> Abstract PubMed

Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth-Metz M, Sörensen N, Graf N, Emser A, Pietsch T, Wolff JEA, Kortmann RD, Kuehl J? for the German Pediatric Brain Tumor Study Group
Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone.
NEJM 352:978-986, 2005  (IF:34.833, 2003) -> Abstract PubMed

Gottschling S, Meyer S, Krenn T, Lothschütz D, Reinhard H, Graf N, Shamdeen GM
Effects of short-term propofol administration on pancreatic enzymes and triglyceride levels in children.
Anaesthesia 60:660-663, 2005 (IF: 2.041, 2003) -> Abstract PubMed

Schlomm T, Gunawan B, Schulten HJ, Sander B, Thangavelu K, Graf N, Leuschner I, Ringert RH, Füzesi L
Effects of Chemotherapy on the Cytogenetic Constitution of Wilms Tumor.
Clin Cancer Res, 11:4382-4387, 2005 (IF: 6.511, 2003) -> Abstract PubMed

Gantenbein C, Graf N, Ruprecht KW
Visusminderung bei plötzlicher Netzhautblutung.
Der Ophthalmologe 102:812-814, 2005 (IF: 0.508, 2003)

Wagner S, Reinert C, Schmid H-J, Liebeskind A-K, Jorch N, Längler A, Graf N, Warmuth-Metz M, Pietsch T, Peters O, Wolff JEA
High?dose Methotrexate prior to simultaneous radiochemotherapy in children with malignant high-grad gliomas.
Anticancer Res 25:2583-2588, 2005 (IF: 1.347, 2003) -> Abstract PubMed

Zirn B, Samans B, Spangenberg C, Graf N, Eilers M, Gessler M
All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo.
Oncogene 24:5246-5251, 2005 (IF: 6,495, 2003) -> Abstract PubMed

Meyer S, Gottschling S, Biran T, Georg T, Ehlayil K, Graf N, Gortner L
Assessing the risk of mortality in paediatric cancer patients admitted to the paediatric intensive care unit: a novel risk score?
Eur J Pediatr 164:563-567, 2005 (IF: 1.157, 2003) -> Abstract PubMed

Gottschling S, Meyer S, Krenn T, Reinhard H, Lothschuetz D, Nunold H, Graf N
Propofol Versus Midazolam/Ketamine for Procedural Sedation in Pediatric Oncology.
J Pediatr Hematol Oncol 27:471-476, 2005 (IF: 1.463, 2003) -> Abstract PubMed

Schenk JP, Schrader C, Furtwängler R, Ko HS, Leuschner I, Graf N, Tröger J
MRT Morphologie und Staging des kongenitalen mesoblastischen Nephroms: Auswertung einer Fallsammlung mit 20 Patienten.
Fortschr Röntgenstr 177:1373-1379, 2005 (IF: 1.786, 2003)

Gottschling S, Larsen R, Meyer S, Graf N, Reinhard H
Acute pancreatitis by short-term prpofol administration. Case report.
Pediatric Anesthesia 15:1006-1008, 2005 (IF:1.105, 2004) -> Abstract PubMed

Schenk JP, Günther P, Schrader C, Ley S, Furtwängler R, Leuschner I, Edelhäuser M, Graf N, Tröger J
Kindliche Nierentumore ? Relevanz der Bildgebung.
Radiologe 45:1112-1123, 2005 (IF: 0.626, 2003)

Längler A, Spix C, Gottschling S, Graf N, Kaatsch P
Elternbefragung zur Anwendung alternativer und komplementärer Behandlungsmethoden in der Kinderonkologie in Deutschland.
Klin Päd 217:357-364, 2005 (IF: 0.413, 2003)

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2004

Siemer S, Lehmann J, Reinhard H, Graf N, Löffler G, Hendrik H, Remberger K, Stöckle M
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child.
Int J Urology 11:50-51, 2004 (IF: 0.683, 2003) -> Abstract PubMed

Günther P, Tröger J, Graf N, Waag KL, Schenk JP
MR volumetric analysis of the course of nephroblastomatosis under chemotherapy in childhood.
Pediatr Radiology 34:660-664, 2004 (IF: 0.942, 2003) -> Abstract PubMed

Weirich A, Ludwig R, Graf N, Abel U, Leuschner I, Vujanic GM, Mehls O, Boos J, Beck J, Royer-Pockora B, Voûte PA
Survival in nephroblastoma treated according to the trial and study SIOP 9/GPOH with respect to relapse and morbidity.
Ann Oncol 15:808-820, 2004 (IF: 3.605, 2003) -> Abstract PubMed

Meyer S, Reinhard H, Gottschling S, Nunold H, Graf N
Pulmonary dysfunction in pediatric oncology patients.
Pediatric Hematology and Oncology, 21:175-195, 2004 (IF: 0.671, 2003) -> Abstract PubMed

Meyer S, Aliani S, Graf N, Gottschling S
Inter- and intraindividual variability in ketamine dosage in repetitive procedures in children with malignancies.
Pediatric Hematology and Oncology 21:161-166, 2004 (IF: 0.671, 2003) -> Abstract PubMed

Garde S, Baumgarten B, Basu O, Graf N, Haux R, Herold R, Kutscha U, Schilling F, Selle B, Spiess C, Wetter T, Knaub P
A Meta-Model of Chemotherapy Planning in the Multi-Hospital/Multi-Trial-Center-Environment of Pediatric Oncology.
Method Inform Med 43:171-183, 2004 (IF: 1.417, 2003) -> Abstract PubMed

S. Garde, B. Baumgarten, O. Basu, N. Graf, R. Haux, R. Herold, U. Kutscha, F. Schilling, B. Selle, C. Spiess, T. Wetter, P. Knaup
A Meta-Model of Chemotherapy Planning in the Multi-Hospital/Multi-Trial-Center-Environment of Pediatric Oncology.
Selected for the IMIA Yearbook 2006 (Section: Decision Support, Knowledge Representation and Management). Haux R, Kulikowski C, editors. IMIA Yearbook of Medical Informatics 2006. Methods Inf Med 2006; 45 Suppl 1: S83. Original Paper available from: Methods Inf Med 2004; 43(2): 171-83 -> Abstract PubMed

Reinhard H, Semler O, Bürger D, Bode U, Flentje M, Göbel U, Gutjahr P, Leuschner I, Maaß E, Niggli F,  Scheel-Walter HG, Stöckle M, Thüroff JW, Tröger J, Weirich A, von Schweinitz D, Zoubek A, Graf N for the SIOP 93-01/GPOH trial and study
Results of  the SIOP 93-01 / GPOH trial and study for the treatment of patients with unilateral nonmetastatic Wilms Tumor.
Klin Pädiatr 216:132-140, 2004 (IF: 0.413, 2003) -> Abstract PubMed

de Kraker J, Graf N, van Tinteren H, Pein F,  Sandstedt B, Godzinski J, Tournade MF for the International Society of Paediatric Oncology Nephroblastoma Trial Committee
Reduction of postoperative chemotherapy in children with stage I intermediate risk and anaplasia Wilms?Tumour . The SIOP 93-01 randomised trial.
Lancet 364:1229-1235, 2004  (IF: 18,316, 2003) -> Abstract PubMed

Szavay P, Luithle T, Semler O, Graf N, Fuchs J
Surgery of Cavoatrial Tumor Thrombus in Nephroblastoma ? A Report of the SIOP/GPOH Study.
Pediatric Blood & Cancer, 43:40-45, 2004 (IF: 1.737, 2003 [Medical and Pediatric Oncology]) -> Abstract PubMed

Schenk JP, Engelmann D, Rohrschneider W, Zieger B, Semler O, Graf N, Tröger J
Rhabdoidtumoren der Niere im Kindesalter. Eine retrospektive radiomorphologische Analyse von 22 im Rahmen der Nephroblastomstudie SIOP 93-01-GPOH registrierten Fällen.
RöFo 176:965-971, 2004 (IF: 1.786, 2003)

Schenk JP,  Waag KL, Graf N, Wunsch R, Jourdan C, Behnisch W, Tröger J, Günther P
3D-Visualisierung in der MRT zur Operationsplanung von Wilms-Tumoren.
RöFo 176:1447-1452, 2004 (IF: 1.786, 2003)

van den Heuvel-Eibrink MM, Graf N, Pein F, Sandstedt B, van Tinteren H, van der Vaart KE, de Kraker J
Intracranial Relapse in Wilms Tumor Patients.
Pediatr Blood & Cancer 43:1-5, 2004 (IF: 1.737, 2003 [Medical and Pediatric Oncology]) -> Abstract PubMed

Reinhard H, Aliani S, Rübe C, Stöckle M, Leuschner I, Graf N
Wilms Tumor in Adults ? Results of the SIOP 93-01/GPOH study.
J Clin Oncol 22:4500-4506, 2004  (IF: 10.864, 2003)

Gottschling S, Meyer, S, Reinhard H, Krenn T, Graf N
First Report of a Vincristine Dose-Related Raynaud's Phenomenon in an Adolescent With Malignant Brain Tumor.
J Ped Hematol Oncol 26:768-769, 2004 (IF: 1.463, 2003) -> Abstract PubMed

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2003

Aliani S, Altmeyer K, Niedermayer I, Strowitzki M, Sitzmann FC, Graf N
Medulloblastoma with extensive nodularity in nevoid basal cell carcinoma syndrome.
Med Ped Oncol 40:266-267, 2003 (IF: 1.737) -> Abstract PubMed

Meyer S, Gottschling S, Georg T, Lothschutz D, Graf N, Sitzmann FC
Gamma-hydroxybutyrate Versus Chlorprothixene/Phenobarbital Sedation in Children Undergoing MRI Studies.
Klin Padiatr 215:69-73, 2003 (IF: 0.413, 2003) -> Abstract PubMed

Niemeyer P, Türeci Ö, Eberle T, Graf N, Pfreundschuh M, Sahin U
Expression of serologically identified tumor antigens in acute leukemias.
Leuk Res 27: 655-560, 2003 (IF: 2.333) -> Abstract PubMed

Meyer S, Aliani S, Graf N, Reinhard H, Gottschling S Sedation with midazolam and ketamine for invasive procedures in children with malignancies and hematological disorders: a prospective study with reference to the sympathomimetic properties of ketamine.
Pediatr Hematol Oncol 20:291-301, 2003 (IF: 0.671) -> Abstract PubMed

Hempel L, Sauerbrey A, Zintl F, Weirich A, Lemmer A, Graf N
Successful Management of a Child With Clear Cell Sarcoma of the Kidney (CCSK) and Multifocal Bone Metastases at Diagnosis.
Med Ped Oncol 41:97-99, 2003 (IF: 1.737) -> Abstract PubMed

Haecker FM, von Schweinitz D, Harms D, Buerger D, Graf N
Partial nephrectomy for unilateral Wilms tumor: results of study SIOP 93-01/GPOH.
J Urol 170:939-942, 2003 (IF: 3.297); zusätzlich: Diskussion 943-944 -> Abstract PubMed

Kremens B, Gruhn B, Klingebiel T, Hasan C, Laws HJ, Koscielniak E, Hero B, Selle B, Niemeyer C, Finkenstein FG, Schulz A, Wawer A, Zintl F, Graf N
High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma.
Bone Marrow Transplant 31:1185, 2003 (IF: 2.172) -> Abstract PubMed

Gottschling S, Reinhard H, Meyer S, Krenn T, Dörflinger D, Graf N
Severe encephalopathy caused by intraparenchymal methotrexate application due to the design of the intraventricular catheter.
Med Ped Oncol 41:491-497, 2003 (IF: 1.737) -> Abstract PubMed

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2002

Wolff JE, Gnekow AK, Kortmann RD, Pietsch T, Urban C, Graf N, Kuhl J
Preradiation chemotherapy for pediatric patients with high-grade glioma.
Cancer 94:264-271, 2002 (IF: 3.941) -> Abstract PubMed

Meyer S, Reinhard H, Graf N, Krenn T, Aliani S, Püschel W, Schwaiger C, Schneider G
Solider pseudopapillärer Tumor des Pankreas bei einem 9-jährigen Mädchen.
Klin Pädiatr 214:316-318, 2002 (IF: 0.457)

Graf N, Paulussen M, Huf T, Ganslandt T, Stahl J, Jürgens H
Telemedizin in der Pädiatrischen Onkologie. Ergebnisse eines Fragebogens des Kompetenznetzes Pädiatrische Onkologie.
Klin Pädiatr 214:8-19, 2002 (0.457)

Meyer S, Reinhard H, Graf N, Kramann B, Schneider G
Arterial embolization of a secondary aneurysmatic bone cyst of the thoracic spine prior to surgical excision in a 15-year-old girl.
Eur J Radiol 43:79-81, 2002 (IF : 1.118) -> Abstract PubMed

Marx M, Langer T, Graf N, Aliani S, Hausdorf G, Stöhr W, Ludwig R, Beck JD
Multicentre analysis of anthracycline-induced cardiotoxicity in children following treatment according to the nephroblastoma studies SIOP No.9/GPOH and SIOP 93-01/GPOH.
Med Ped Oncol 39:18-24, 2002 (IF: 1.216) -> Abstract PubMed

Lorenz M, Graf N, König J, Sitzmann FC, Ruprecht KW, Käsmann-Kellner B
Augenbefunde bei Kindern mit Hirntumor - Datenbasis für einen Nachsorgeplan.
Klin Pädiatr 214:117-125, 2002 (IF: 0.457)

Merzweiler A, Ehlerding H, Creutzig U, Graf N, Hero B, Kaatsch P, Zimmermann , Weber R, Knaup P
Terminologiestandardisierung in der Pädiatrischen Onkologie ? der Basisdatensatz.
Klin Pädiatr 214: 212-217, 2002 (0.457)

Kremens B, Hero B, Esser J, Weinel P, Filger-Brillinger J, Fleischhack G, Graf N, Grüttner HP, Niemeyer C, Schulz A, Wickmann L, Berthold F
Ocular symptoms in children treated with human-mouse chimeric anti_GD2 mAB ch 14.18 for neuroblastoma.
Cancer Immunology Immunotherapy 51:107-110, 2002 (IF: 2.759) -> Abstract PubMed

Hero B, Graf N, Simon T, Weirich A, Tröger J, Berthold F
Neuroblastoma preoperatively treated as nephroblastoma: does inadequate therapy worsen the prognosis.
Klin Pädiatr 214:157-161, 2002 (IF: 0.457) -> Abstract PubMed

Meyer S, Romeike B, Aliani S, Feiden W, Graf N, Reinhard H
Meningeoangiomatose mit assoziiertem Meningeom bei einem 4-jährigen Mädchen mit fokalem Krampfanfall.
Nervenarzt 73:990-994, 2002 (IF: 0.886)

Aliani S, Meyer S, Krenn T, Müller-Molaian I, Graf N
Das "Vanishing Bile Duct Syndrome" nach allogener Knochenmarktransplantation.
Klin Pädiatr 214:371-374, 2002 (IF: 0.457)

Kremens B, Gruhn B, Klingebiel T, Hasan C, Laws H-J, Koscielniak E, Hero B, Selle B, Niemeyer C, Finckenstein FG, Schulz A, Wawer A, Zintl F, Graf N
High-dose chemotherapy with autologous stemcell rescue in children with nephroblastoma.
Bone Marrow Transplantation 30:893-898, 2002 (IF: 2.378) -> Abstract PubMed

Graf N
Kampf gegen das weiße Blut. Kasuistik ALL bei Kindern.
Via medici 5:58-61, 2002 (IF: nicht gelistet)

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2001

Weirich A, Leuschner I, Harms D, Vujanic GM, Tröger J, Abel U, Graf N, Schmidt D, Ludwig R, Voute PA
Clinical impact of histologic subtypes in localized non-anaplastic nephroblastoma treated according to the trial and study SIOP-9 / GPOH.
Annals of Oncology 12:311-319, 2001(IF: 3.153) -> Abstract PubMed

Duchow J, Schmitt E, Graf N
Thoracic spondylitis mimicking idiopathic scoliosis: a case report.
J Pediatr Orthop B 10:105-108, 2001 (IF: 0.468) -> Abstract PubMed

Fleischhack G, Hassan C, Graf N, Mann G, Bode U
IDA-FLAG - An effective reinduction therapy for poor prognosis AML of childhood - Report of a Multicenter Phase II Trial.
Haematol Blood Transf 40:544-554, 2001(IF: nicht gelistet)

Meyer S, Reinhard H, Menges M, Püschel W, Graf N
Eisenmangelanämie als Leitsymptom einer glutensensitiven Enteropathie bei einem 16-jährigen Mädchen.
Monatsschr Kinderheilkd 149:908-913 2001(IF: 0.134)

Müller HL, Bueb K, Bartels U, Roth C, Harz K, Graf N, Korinthenberg R, Bettendorf M, Kühl J, Gutjahr P, Sörensen N, Calaminus G
Obesity after childhood craniopharyngeoma - German multicenter study on pre-operative risk factors and quality of life.
Klin Pädiatr 213:244-249, 2001(IF: 0.614) -> Abstract PubMed

Reinhard H, Seyfert U, Krenn T, Mörsdorf S, Aliani S, Graf N
Comparison of Prefiltration and bedside Filtration in thrombocytopenic children with maligannt diseases.
Infus Ther Transfus Med 28:344-348, 2001 (IF: 0.281)

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2000

Creutzig U, Körholz D, Niemeyer Ch, Kabisch K, Graf N, Reiter A, Scheel-Walter H, Bender-Götze Ch, Behnisch W, Hermann J, Mann G, Ritter J, Zimmermann M
3x14 mg/m² Idarubicin during induction: results of a pilot study in children with AML.
Leukemia 14:340-342, 2000 (IF: 3.736)    -> Abstract PubMed

Niedermayer I, Graf N, Schmidbauer J, Reiche W, Feiden W
Cerebroretinal vasculopathy mimicking a brain tumor.
Neurology 54:1878-1879, 2000 (IF: 4.781) -> Abstract PubMed

Weigand M, Frei E, Graf N, Wiessler M
Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
J Cancer Res Clin Oncol 126:407-411, 2000 (IF: 2.194, 2001) -> Abstract PubMed

Creutzig U, Körholz D, Niemeyer Ch, Kabisch K, Graf N, Reiter A, Scheel-Walter H, Bender-Götze Ch, Behnisch W, Hermann J, Mann G, Ritter J, Zimmermann M
Toxicity and effectivity of high-dose idarubicin during AML induction therapy: Results of a pilot study in children.
Klin Pädiatr 212:163-168, 2000 (IF: 0.503)

Schmidbauer JM, Voges M, Käsmann-Kellner B, Graf N, Henn W, Ruprecht KW
Hereditäre okklusive zerebroretinale Vaskulopathie bei zwei Schwestern.
Klin Monatsbl Augenheilkd  217:246-251, 2000 (IF: 0.406)

Niedermayer I, Reiche W, Graf N, Mestres P, Feiden W
Cerebroretinal vasculopathy and leukencephalopathy mimicking a brain tumor. Report of two early-onset cases with Fanconi's anemia-like phenotypes suggesting an autosomal-recessive inheritance pattern.
Clinical Neuropathology 19:285-295, 2000 (IF: 1.012) -> Abstract PubMed

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1999

Creutzig U, Zimmermann M, Ritter J, Henze G, Graf N, Löffler H, Schellong G
Definition of a standard-risk group in children with AML.
Br J Haematol 104:630-639, 1999 (IF: 3.204) -> Abstract PubMed

Fischer N, Kopper B,  Graf N, Schlehofer JR, Grässer FA, Müller-Lantzsch N
Functional Analysis of Different LMP 1 Proteins isolated from Epstein-Barr Virus (EBV)-positive Carriers.
Virus Res 60:41-54, 1999 (IF: 1.568)

Graf N, Winkler K, Betlemovic M, Fuchs N, Bode U
Methotrexate pharmacokinetics and prognosis in osteosarcoma: Classic Papers and Current Comments
Cancer Pharmacology 4:62-71, 1999 (IF: 7.963)

Käsmann-Kellner B, Graf N, Efflein E, Ruprecht KW, Sitzman FC
Verlauf eines Retinoblastoms unter homöopathischer Therapie.
Klinische Monatsblätter für Augenheilkunde 214:12-16, 1999 (IF: 0.423)

Kaspers GJL, Zwaan ChM, Veerman AJP, Rots MG, Pieters R, Bucsky P, Domula M, Goebel U, Graf N, Havers W, Jorch N, Kabisch K, Spaar HJ, Ritter J, Creutzig U
Cellular drug resistance in acute myeloid leukemia: Literature review and preliminary analysis of an ongoing colloborative study. 
Klin Pädiatr 211:239-244, 1999 (IF: 0.414) -> Abstract PubMed

Bielack S, Kempf-Bielack B, Schwenzer D, Birkfellner T, Delling G, Ewerbeck V, Exner GU, Fuchs N, Gobel U, Graf N, Heise U, Helmke K, von Hochstetter AR, Jurgens H, Maas R, Munchow N, Salzer-Kuntschik M, Treuner J, Veltmann U, Werner M, Winkelmann W, Zoubek A, Kotz R
Neoadjuvante Therapie des lokalisierten Osteosarkoms der Extremitäten. Erfahrungen der Cooperativen Osteosarkomstudiengruppe COSS an 925 Patienten.
Klin Pädiatr 211:260-270, 1999 (IF: 0.414)

Ludwig R, Weirich A, Abel U, Hofmann W, Graf N, Tournade MF
Hepatotoxicity in patients treated according to the Nephroblastoma trial & study SIOP-9 / GPOH.
Med Ped Oncol 33:462-469, 1999 (IF: 1.518) -> Abstract PubMed

Weigand M, Frei E, Graf N, Buchholz B, Wolfrom C, Breuer A, Wiessler M
Mechanisms of resistance to methotrexate in childhood acute lymphoblastic leukemia: circumvention of thymidylate synthase inhibition.
J Cancer Res Clin Oncol 125:513-519, 1999 (IF: 1.052) -> Abstract PubMed

Reinhard H, Lindinger A, Geib-König R, Graf N
Churg-Strauss-Syndrom bei einem 15jährigen Jungen.
Klinische Pädiatrie 211:423-426, 1999 (IF: 0.414)

Reiter A, Schrappe M, Tiemann M, Ludwig WD, Yakisan E, Zimmermann M, Mann G, Chott A, Ebell W, Klingebiel T, Graf N, Kremens B, Müller-Weihrich S, Plüss HJ, Zintl F, Henze G, Riehm H
Improved Treatment Results in Childhood B-Cell Neoplasms With Tailored Intensification of Therapy: A Report of the Berlin-Frankfurt-Münster Group Trial NHL-BFM 90.
Blood 94:3294-3306, 1999 (IF: 8.782) -> Abstract PubMed

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1998

Scholz M, D Kühn, H.-G. Limbach, G Löffler, JR Moringlane, N GrafArachnoidalzyste als Ursache eines Hypernatriämie-Hypodypsie-Syndroms.
Monatsschr Kinderheilkd 146:603-607, 1998 (IF: 0.191)

Flentje M, Weirich A, Graf N, Potter R, Zimmermann H, Ludwig R
Abdominal irradiation in unilateral nephroblastoma and its impact on local control and survival.
Int J Radiat Oncol Biol Phys 40:163-169, 1998 (IF: 2.589) -> Abstract PubMed

Dördelmann M, Schrappe M, Reiter A, Zimmermann M, Graf N, Schott G, Lampert F, Harbott J, Niemeyer C, Ritter J, Dörffel W, Nessler G, Kühl J, Riehm H
Down´s syndome in childhood acute lymphoblastic leukemia: clinical characteristics and treatment outcome in four consecutive BFM trials. Berlin-Frankfurt-Münster Group.
Leukemia 12:645-651, 1998 (IF: 3.163)

Klamt B, M Schulze, Thate C, Mares J, Goetz P, Kodet R, Scheulen W, Weirich A, Graf N, Gessler M
Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters.
Genes Chromosomes Cancer 22:287-294, 1998 (IF: 3.804) -> Abstract PubMed

Kühl J, Müller HJ, Berthold F, Kortmann RD, Deinlein F, Maaß E, Graf N, Gnekow A, Scheurlen W, Göbel U, Wolff JEA, Bamberg M, Kaatsch P, Kleihues P, Rating D, Sörensen N, Wiestler OD
Preradiation chemotherapy of children and young adults with malignant brain tumors: Results of the german pilot trial HIT´88/´89.
Klin Pädiatr: 210:227-233, 1998 (IF: 0.406)

Fleischhack G, Hasan C, Graf N, Mann G, Bode U
IDA-FLAG (idarubicin, fludarabine, cytarabine, G-CSF), an effective remission-induction therapy for poor-prognosis AML of childhood prior to allogeneic or autologous bone marrow transplantation: experiences of a phase II trial.
Br J Haematol 102:647-655, 1998 (IF: 3.209)  -> Abstract PubMed

Fuchs N, Bielack S, Epler D, Bieling P, Delling G, Körholz D, Graf N, Heise U, Jürgens H, Kotz R, Salzer-Kuntschik M, Weinel P, Werner M, Winkler K
Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group´s protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs.
Annals of Oncology 9:893-899, 1998 (IF: 2.867)

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1997

Ludwig R, Weirich A, Bürger D, Graf N, Harms D, Kaatsch P, Pötter R, Rieden K, Tröger J, Zimmermann H
Durchführung eines neuen Therapiekonzepts für Nephroblastome (SIOP 9/GPOH) im Bereich der Gesellschaft für Pädiatrische Onkologie und Hämatologie.
Monatsschr Kinderheilkd 145:128-135, 1997

Karadiakos N, Schwaiger Ch, Reinhard H, Graf N
Der Broviac/Hickman-Katheter bei langfristiger Zytostatika- und Infusionstherapie
Pädiat Prax 52:461-470, 1997

Scholz M, Salamon-Looijen,  Pfau B, Kujat Ch, Hille K, Graf N
Morbus Coats bei einem Jungen mit Di-George Syndrom
Monatsschr Kinderheilkd 145:1061-1065, 1997

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1996

Reinhard H, Brunner J, Dockter G, Graf N, Müller J, Scholz M, Wagner EM
Rhabdomyolyse bei atypischer Pneumonie
Pädiatr Grenzgeb 34:503-506, 1996

Fleischhack G, Graf N, Hasan C, Ackermann M, Breu H, Zernikow B, Bode U
IDA-FLAG (idarubicin, fludarabine, high-dose cytarabine, granulocyte colony-stimulating factor) - An effective regimen in relapsed acute myelogenous leukemia in childhood.
Klin Pädiatr 208:229-235, 1996 -> Abstract PubMed

Steilen-Gimbel H, Remberger K, Graf N, Steudel WI, Zang KD, Henn W
A novel site of DNA amplification on chromosome 1p32-33 in a rhabdomyosarcoma revealed by comparative genomic hybridization
Human Genetics 97:87-90, 1996 -> Abstract PubMed

Scholz M, Graf N, Steffens J, Schönhofen H, Jeannelle JP, Schofer O, Sitzmann FC
Mumpsorchitis im Jugend- und Erwachsenenalter. Ein vergessenes Krankheitsbild
Dtsch Ärztebl 33A:2087-2090, 1996

Hempel L, Kremens B, Weirich A, Zintl F, Graf N, Ludwig R
High dose consolidation with autologous stem cell rescue (ASCR) for nephroblastoma initially treated according to the SIOP 9/GPOH trial and study
Klin Pädiatr 208:186-189, 1996 -> Abstract PubMed

Graf N, Weirich A, de Kraker J
Letter to the Editor: Staging problems in the pre-operative chemotherapy of Wilms´tumour
British J Urology 78:479-480, 1996

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1995

Moringlane JR, Reif J, Donauer E, Graf N, Feiden W
Microsurgery of cerebral lesions under stereotactic conditions
Minim Invas Neurosurg 38: 117-122, 1995 -> Abstract PubMed

Scholz M, Reinhard H, Riesinger P, Müller J, Ehlayil K, Graf N
Systemische Metastasen im Rezidiv bei Kindern mit malignem Hirntumor
Pädiat Prax 49: 415-421, 1995

Seyger MM, Ritterbach J, Creutzig U, Gnekow A, Göbel U, Graf N, Reiter A, Lampert F, Harbott J
12q13, a new recurrent breakpoint in acute non-lymphoblastic leukemia
Cancer Genet Cytogenet 80: 23-28, 1995 -> Abstract PubMed

Graf N, Riesinger P, Reinhard H
Retinoids in the treatment of acute promyelocytic leukemia. Review of the literature.
Klin Pädiatr 207: 43-47, 1995 -> Abstract PubMed

Siemer S, Graf N, Netzer M, Steffens J
Nebennierenrindenkarzinome im Kindesalter
Akt. Urologie 26:406-409, 1995

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1994

de Boer M, Hilarius-Stokman PM, Hossle JP, Verhoeven AJ, Graf N, Kenney RT, Seger R, Roos D
Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers
Blood 83: 531-536, 1994 -> Abstract PubMed

Dorn A, Graf N, Pees HW
Intrazelluläre Messung von Doxorubicin in Blasten von AML-Patienten mittels Durchflusszytometrie
Monatsschr Kinderheilkd 142: 524-526, 1994

Graf N, Winkler K, Betlemovic M, Fuchs N, Bode U
Methotrexate pharmacokinetics and prognosis in osteosarcoma
J Clin Oncol 12: 1443-1451, 1994 -> Abstract PubMed

Reiter A, Schrappe M, Yakisan E, Sauter S, Henzler D, Zimmermann M, Graf N, Fengler R, Kühl J, Fleischhack G,  Dörffel W, Kluba U, Riehm H
Therapiestudie NHL-BFM 90 zur Behandlung maligner Non-Hodgkin-Lymphome bei Kindern und Jugendlichen. Teil 2: Eine Zwischenanalyse der Therapiegruppe Non-B-NHL. BFM Studiengruppe
Klin Pädiatr 206: 234-241, 1994

Torfah E, Sitzmann FC, Graf N, Moringlane JR, Müller J, Riesinger P
Ungewöhnlicher Verlauf eines pilozytischen Astrozytoms
Pädiatrische Praxis 47: 439-446, 1994

Velten M, Graf N, Haas HJ
Inversvoltometrische Platinbestimmung im Blut aus Filterpapierstanzen nach Infusion von cis- bzw. Carboplatin
Pädiatrie Grenzgebiete 33: 157-163, 1994

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1993

Dorn A, Graf N, Pees HW
Intrazelluläre Messung von Anthracyclinen mittels Durchflußzytometrie
Pädiatr Pädol 28: 157-163, 1993

Kühl J, Berthold F, Bode U, Bucsky P, Graf N, Gnekow A, Maass E, Bamberg M, Kaatsch P, Kleihues P, Rating D, Riehm H, Sörensen N
Preradiation chemotherapy of children with poor-prognosis medulloblastoma: response rate and toxicity of the ifosfamide containing multidrug regimen HIT 88/89
Am J Hematol Oncol 15 Suppl A: 567-571, 1993

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1992

Bambauer R, El-Saadi, Graf N, Jesberger HJ, Limbach HG, Cordes H
Plasmapheresis in newborns with hyperbilirubinemia
Artifical Organs 16: 472-476, 1992 -> Abstract PubMed

Jost W, Graf N, Quinten A, Dockter G, Kretschmer A
Neurozystizerkose bei einem 8jährigen Mädchen
Monatsschr Kinderheilkd 140: 105-107, 1992

Kretschmer A, Dewes W, Graf N, Hau U, Kubale R, Kramann B, Sitzmann FC
MR-Tomographie der Unterschenkel bei Kindern mit Erkrankungen des hämatopoetischen Systems
Nuklearmedizin 31: 186-191, 1992

Kretschmer A, Ballof U, Graf N, Junk B, Benz P, Hau U, Dewes W, Kramann B
Zur Diagnostik von Knochenmarkläsionen im MR-Tomogramm bei Kindern mit Erkrankungendes hämatopoetischen Systems unter besonderer Berücksichtigung der posttherapeutischen Veränderungen
Röfo Fortschr Geb Röntgenstr Neuen Bildgeb Verfahr 156: 570-575, 1992

Kühl J, Rating D, Berthold F, Graf N, Maass E, Gnekow A, Weinel P, Göbel U, Havers W, Lakomek M, Gutjahr P, Urban Ch, Bamberg M, Bode U, Kaatsch P, Kleihues P, Niethammer D, Sörensen N
Ergebnisse der multizentrischen Chemotherapiepilotstudie HIT ´88/89.
In: Köhler B, Keimer R: Aktuelle Neuropädiatrie. Berlin, Heidelberg: Springer Verlag, 1992, S. 176-184

Pees HW, Radtke H, Schwamborn J, Graf N
The BFM-protocol for HIV-negative Burkitt's lymphomas and L3 ALL in adult patients: a high chance for cure
Ann Hematol 65: 201-205, 1992 -> Abstract PubMed

Seider A, Graf N, Sitzmann FC
Wertigkeit der Sialinsäurebestimmung im Serum bei Kindern
Pädiatr Pädol 27: 43-46, 1992

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1991

Bieling P, Bielack S, Delling G, Jürgens H, Kotz R, Dose C, Astheimer H, Exner G, Gadner H, Graf N, Ritter J, Salzer-Kuntschik M, Weinel P, Winkler K
Neoadjuvante Chemotherapie des Osteosarkoms. Vorläufige Ergebnisse der kooperativen Osteosarkom-Studie COSS-86
Klin Pädiatr 203: 220-230, 1991

Haag R, Graf N, Jost W
Subjektiv erlebte Ängstlichkeit als Aspekt der Krankheitsverarbeitung bei Kindern mit bösartigen Erkrankungen
Prax Kinderpsychol Kinderpsychiatr 40: 78-84, 1991

Graf N, Hille A, Jost W, Müller J
Polyvalente Immunglobuline in der Prophylaxe von viralen Infektionen bei Kindern mit neoplastischen Erkrankungen unter immunsuppressiver Therapie
Pädiatr Pädol 26: 187-191, 1991

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1990

Bambauer R, Jutzler GA, Graf N, Jesberger HJ, Limbach HG, Sitzmann FC, Keuth U
The role of therapeutic plasma exchange in the management of pediatric disease
Prog Clin Biol Res 337: 383-385, 1990 -> Abstract PubMed

Dietz R, Graf N
Zur Therapie des Medulloblastoms - Ergebnisse aus den Jahren 1968 bis 1985
Strahlenther Onkol 166: 683-687, 1990

Jost W, Graf N, Pindur G, Sitzmann FC
Intraspinale, extradurale Blutung bei einem 7jährigen Jungen mit Hämophilie B
Monatsschr Kinderheilkd 138: 36-37, 1990

Will N, Seger RA, Betzler C, Dockter G, Graf N, Büttner M, Irle C, Tiercy JM, Sitzmann FC
Bare lymphocyte syndrome--combined immunodeficiency and neutrophil dysfunction
Eur J Pediatr 149: 700-704, 1990 -> Abstract PubMed

Winkler K, Bielack S, Delling G, Salzer-Kuntschik M, Kotz R, Greenshaw C, Jürgens H, Ritter J, Kusnierz-Glaz C, Erttmann R, Gädicke G, Graf N, Ladenstein R, Leyvraz S, Mertens R, Weinel P
Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (Study COSS-86)
Cancer 66: 1703-1710, 1990 -> Abstract PubMed

Graf N, Bambauer R, Jost W, Schäfer M
Der Stellenwert der Plasmapherese und des Cyclosporin A in der Behandlung des systemischen Lupus erythematodes
Monatsschr Kinderheilkd 138: 395-398, 1990

Graf N, Breitenmoser M, Jobke A, Kaatsch P
Malignome in Familien mit krebskranken Kindern
Klin Pädiatr 202: 282-287, 1990

Graf N, Jost W, Müller J, Keller HE, Sitzmann FC
Einfluß der Methotrexatpharmakokinetik und des Leukovorinrescues auf die Prognose des Osteosarkoms
Klin Pädiatr 202: 340-346, 1990 -> Abstract PubMed

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1989

Bambauer R, Jutzler GA, Jesberger HJ, Löffler G, Limbach HG, Graf N, Richter J, Volkmer I
Hemofiltration and plasmapheresis in newborns using a small blood pump system
ASAIO Trans 35: 578-579, 1989 -> Abstract PubMed

Henze G, Fengler R, Hartmann R, Dopfer R, Göbel U, Graf N, Jürgens H, Niethammer D, Ritter J, Schellong G, Siebert W
Chemotherapy for bone marrow relapse of childhood acute lymphoblastic leukemia
Cancer Chemother Pharmacol 24 Suppl 1: 16-19, 1989

Reif J, Graf N
Spinal space occupying lesions in thalassemia major
Neurosurg Rev 12: 323-331, 1989 -> Abstract PubMed

Sitzmann FC, Graf N, Haas J, Seider A
The clinical significance of two tumour markers
J Clin Lab 1: 64-84, 1989

Graf N, Bach K, Frisch B, Haas HJ, Sitzmann FC
Die klinische Bedeutung der Pseudouridinbestimmung im Urin von Kindern und Jugendlichen
Klin Pädiatr 201: 154-162, 1989

Zabransky S, Müller J, Graf N
Familiäres medulläres C-Zellkarzinom der Schilddrüse mit Lungenmetastasen bei einer 14jährigen
Extracta Paediatrica 13: 132-140, 1989

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1988

Bambauer R, Jutzler GA, Jesberger HJ, Graf N, Limbach HG, Sitzmann FC, Keuth U
Therapeutischer Plasma-Austausch beim hämolytisch-urämischen Syndrom
Dtsch Med Wochenschr 113: 1245-1249, 1988

Lindinger A, Graf N, Hoffmann W
Kardiale Dysfunktion bei Kindern mit Thalassämia major
Klin Pädiatr 200: 102-107, 1988

Winkler K, Beron G, Delling G, Heise U, Kabisch H, Purfürst C, Berger J, Ritter J, Jürgens H, Gerein V, Graf N, Russe W, Gruemayer ER, Ertelt W, Kotz R, Preusser P, Prindull G, Brandeis W, Landbeck G
Neoadjuvant chemotherapy of osteosarcoma: Results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response
J Clin Oncol 6: 329-337, 1988 -> Abstract PubMed

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1987

Creuzig U, Ritter J, Budde M, Sutor A, Schellong G, Neidhardt M, Henze G, Spaar HJ, Jacobi M, Andler W, Jürgens H, Beck JD, Stollman B, Kornhuber B, Jobke A, Prindull G, Lampert F, Brandeis W, Graf N, Kabisch H
Early deaths due to hemorrhage and leukostasis in childhood acute myelogenous leukemia. Associations with hyperleukocytosis and acute myelogenous leukemia
Cancer 60: 3071-3079, 1987 -> Abstract PubMed

Fengler R, Buchmann S, Riehm H, Berthold F, Dopfer R, Graf N, Holldack J, Jobke A, Jürgens H, Klingebiel T, Kühl J, Spaar HJ, Wüstemann M, Henze G
Aggressive combination chemotherapy of bone marrow relapse in childhood acute lymphoblastic leukemia containing aclacinomycin-A: a multicentric trial
Hämatol Bluttransfus 30: 493-496, 1987

Lampert F, Harbott J, Ludwig WD, Bartram CR, Ritter J, Gerein V, Neidhardt M, Mertens R, Graf N, Riehm H
Acute leukemia with chromosome translocation (4;11): 7 new patients and analysis of 71 cases
Blut 54: 325-335, 1987 -> Abstract PubMed

Moringlane JR, Graf N, Ostertag CB
Stereotaktische Diagnostik von Hirntumoren im Kindesalter als Grundlage für die Therapieplanung
Klin Pädiatr 199: 260-268, 1987

Moringlane JR, Graf N, Ostertag CB
Papel de la exploración estereoáxica en el diagnóstico y tratamiento de los tumores cerebrales del nino
Neurologia (Esp) 2: 202-210, 1987

Reif J, Graf N
Intraspinal mesenchymal chondrosarcoma in a three-year-old boy
Neurosurg Rev 10: 311-314, 1987 -> Abstract PubMed

Schrappe M, Beck J, Brandeis WE, Feickert HJ, Gadner H, Graf N, Havers W, Henze G, Jobke A, Kornhuber B, Kühl J, Lampert F, Müller-Weirich St, Niethammer D, Reiter A, Rister M, Ritter J, Schellong G, Tausch W, Weinel P, Riehm H
Die Behandlung der akuten lymphoblastischen Leukämie im Kindes- und Jugendalter: Ergebnisse der multizentrischen Therapiestudie ALL-BFM 81
Klin Pädiatr 199: 133-150, 1987

Wöckel W, Wernert N, Graf N
Bronchozentrische Granulomatose als Manifestation der alllergischen bronchopulmonalen Aspergillose ohne Asthma bronchiale
Dtsch Med Wochenschr 112: 1043-1047, 1987

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1986

Bambauer R, Jutzler GA, Sitzmann FC, Graf N, Keller HE, Keuth U
Therapeutischer Plasmaaustausch beim hämolytisch-urämischen Syndrom
Nieren- und Hochdruckkrankheiten 15: 109-117, 1986

Beck JB, Gromball J, Ludwig WD, Bode U, Ertelt W, Graf N, Neidhardt M, Nessler G, Spaar HJ, Brandeis W
Neuere Methoden zur Klassifizierung von lymphatischen Leukämiezellen und ihr prognostischer Wert für die Therapieergebnisse
Der Kinderarzt 17: 14-19, 1986

Hohenberger P, Graf N, Sitzmann FC, Rupp S
Verhalten der Glucose-Phosphat-Isomerase bei Kindern mit malignen Erkrankungen
Monatsschr Kinderheilkd 134: 789-793, 1986

Jürgens H, Etspüler G, Göbel V, Göbel U, Graf N, Harms D, Ritter J, Salzer-Kuntschik M, Spaar HJ
Protochemotherapy in Ewing's sarcoma: Results of the GPO CESS 81 trial
Colloq-Inserm 137: 593-597, 1986

Omlor W, Graf N, Wahlen W
Histiozytose X - unterschiedliche klinische Verlaufsformen
Med Welt 37: 689-694, 1986

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1985

Graf N, Müller J: Kasuistik
Otitis externa maligna und generalisierte Aspergillose als Komplikation immunsuppressiver Therapie bei einem 14 Jährigen mit ALL
Extracta paediatrica 9: 197-206, 1985

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1984

Bambauer R, Jutzler GA, Stelzer K, Sitzmann FC, Graf N
Is therapeutic plasma exchange indicated for cases of hemolytic uremic syndrome ?
Life Support Systems 2: 211-213, 1984

Jost W, Graf N, Zabransky S
Trachealzyste bei einem 6 Jahre alten Mädchen
Extracta Paediatrica 4: 275-278, 1984

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1983

Wahlen W, Graf N, Nienhaus KH, Müller J
Untersuchungen zur Thrombozytenmorphologie und -funktion unter hochdosierter Immunglobulintherapie bei akuter und chronischer idiopathisch thrombozytopenischer Purpura (ITP)
Klin Pädiatr 195: 17-23, 1983

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