Saarland University Faculty of Medicine
Publikationen

Publikationen

  

 

Hildebrandt K, Klöppel C, Gogel J, Hartenstein V, Walldorf, U. 2022. Orthopedia expression during Drosophila melanogaster nervous system development and its regulation by microRNA-252. Developmental Biology 492, 87-100.

 

Konstantinides N, Holguera I, Rossy AM, Escobar A, Liébaut D, Dudragne L, Chen Y-C, Tran TN, Martinez James AM, Ösel MN, Simon F, Shao Z, Tsankova NM, Fullard JF, Walldorf U, Roussos P, Desplan C. 2022. A comprehensive series of temporal transcription factors in the fly visual system. Nature 604, 316-322.

 

Hildebrandt K, Kolb D, Klöppel C, Kaspar P, Wittling F, Hartwig O, Federspiel J, Findji I, Walldorf U. 2022. Regulatory modules mediating the complex neural expression patterns of homeobrain gene during Drosophila brain development. Hereditas 159:2.

 

Klöppel C, Hildebrandt K, Kolb D, Fürst N, Bley I, Karlowatz R-J, Walldorf U. 2021. Functional analysis of enhancer elements regulating the expression of the Drosophila homeodomain transcription DRx by gene targeting. Hereditas 158:42.

 

Hildebrandt K, Kübel S, Minet M, Fürst, N, Klöppel C, Steinmetz E, Walldorf U. 2021. Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting. Hereditas 158:41.

 

Steinmetz EL, Dewald, DN, Walldorf U. 2021. Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Hippo/Warts Signalling Effector Yorkie. Int. J. Mol. Sci 22:1862

 

Kolb D, Kaspar P, Klöppel T, Walldorf, U. 2021. The Drosophila homeodomain transcription factor Homeobrain is involved in the formation of the embryonic protocerebrum and the supraesophageal brain commissure. Cells & Development 165:203567

 

Hildebrandt K, Bach N, Kolb D, Walldorf U. 2020. The homeodomain transcription factor Orthopedia is involved in development of the Drosophila hindgut. Hereditas 157:46

 

Steinmetz EL, Dewald DN, Luxem N, Walldorf U. 2019. Drosophila Homeodomain-interacting protein kinase (Hipk)
phosphorylates the homeodomain proteins Homeobrain, Empty spiracles and Muscle segment homeobox. Int. J. Mol. Sci 20:1931

 

Steinmetz EL, Dewald DN, Walldorf U. 2018. Homeodomain Interacting Protein Kinase (Hipk) phosphorylates the Drosophila Pax6 homologues Twin of eyeless and Eyeless. Insect Mol. Biol. 27:198-211

 

Kraft KF, Massey EM, Kolb JD, Walldorf U, Urbach R. 2016. Retinal homeobox promotes cell growth, proliferation and survival of mushroom body neuroblasts in the Drosophila brain. Mech. Dev. 142:50-61

 

Blunk AD, Akbergenova Y, Cho RW, Lee J, Walldorf U, Xu K, Zhong G, Zhuang, X, Littleton JT. 2014. Postsynaptic actin regulates active zone spacing and glutamate receptor apposition at the Drosophila neuromuscular junction. Mol. Cell. Neurosci. 61:241-254

 

Dewald DN, Steinmetz EL, Walldorf U. 2014. Homeodomain Interacting Protein Kinase (Hipk) phosphorylates the Small SPOC Family Protein Spenito. Insect Mol. Biol. 23:706-719

 

Ando M, Totani Y, Walldorf U, Furukubo-Tokunaga, K. 2011. TALE-class homeodomain transcription factors, homothorax and extradenticle, control dendritic and axonal targeting of olfactory projection neurons in the Drosophila brain. Dev. Biol. 358(1):122-136

 

Furukubo-Tokunaga K, Adachi Y, Kurusu M, Walldorf U. 2009. Brain patterning defects caused by mutations of the twin of eyeless gene in Drosophila melanogaster. Fly 3(4):263-269

 

Lee W, Andrews BC, Faust M, Walldorf U and Verheyen EM. 2009. Hipk is an essential protein that promotes Notch signal transduction in the Drosophila eye by inhibition of the global co-repressor Groucho. Dev. Biol. 325(1):263-272

 

Hirth F, Kammermeier L, Frei E, Walldorf U, Noll M, Reichert H. 2003. An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila. Development  130(11):2365-2373

 

Davis RJ, Tavsanli BC, Dittrich C, Walldorf U, Mardon G. 2003. Drosophila retinal homeobox (drx) is not required for establishment of the visual system, but is required for brain and clypeus development. Dev. Biol. 259(2):272-287

 

Kusch T, Storck T, Walldorf U, Reuter R. 2002. Brachyury proteins regulate target genes through modular binding sites in a cooperative fashion. Genes & Dev. 16:518-529

 

Hartmann B, Reichert H, Walldorf U. 2001. Interaction of gap genes in Drosophila head: tailless regulates expression of empty spiracles in early embryonic patterning and brain development. Mech. Dev. 109(2):161-172

 

Callaerts P, Leng S, Clements J, Benassayag C, Cribbs D, Kang YY, Walldorf U, Fischbach KF, Strauss R. 2001. Drosophila Pax-6/eyeless is essential for normal adult brain structure and function. J. Neurobiol. 46(2):73-88

 

Kammermeier L, Leemans R, Hirth F, Flister S, Wenger U, Walldorf U, Gehring WJ, Reichert H. 2001. Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development. Mech. Dev. 103(1-2):71-78

 

Nagao T, Endo K, Kawauchi H, Walldorf U, Furukubo-Tokunaga K. 2000. Patterning defects in the primary axonal scaffolds caused by the mutations of the extradenticle and homothorax genes in the embryonic Drosophila brain. Dev. Genes Evol. 210(6):289-299

 

Walldorf U, Binner P, Fleig R. 2000. Hox genes in the honey bee Apis mellifera. Dev. Genes Evol. 210(10):483-492

 

Walldorf U, Kiewe A, Wickert M, Ronshaugen M, McGinnis W. 2000. Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain. Mech. Dev. 96(1):141-144

 

Kurusu M, Nagao T, Walldorf U, Flister S, Gehring WJ, Furukubo-Tokunaga K. 2000. Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genes. Proc. Natl. Acad. Sci. U. S. A 97(5):2140-2144

 

Hartmann B, Hirth F, Walldorf U, Reichert H. 2000. Expression, regulation and function of the homeobox gene empty spiracles in brain and ventral nerve cord development of Drosophila. Mech. Dev. 90(2):143-153

 

Hauck B, Gehring WJ, Walldorf U. 1999. Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc. Natl. Acad. Sci. U. S. A 96(2):564-569

 

Hovemann BT, Ryseck RP, Walldorf U, Stortkuhl KF, Dietzel ID, Dessen E. 1998. The Drosophila ebony gene is closely related to microbial peptide synthetases and shows specific cuticle and nervous system expression. Gene 221(1):1-9

 

Carrera P, Abrell S, Kerber B, Walldorf U, Preiss A, Hoch M, Jackle H. 1998. A modifier screen in the eye reveals control genes for Kruppel activity in the Drosophila embryo. Proc. Natl. Acad. Sci. U. S. A 95(18):10779-10784

 

Hazelett DJ, Bourouis M, Walldorf U, Treisman JE. 1998. decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc. Development 125(18):3741-3751

 

Halder G, Callaerts P, Flister S, Walldorf U, Kloter U, Gehring WJ. 1998. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development 125(12):2181-2191

 

Eggert T, Hauck B, Hildebrandt N, Gehring WJ, Walldorf U. 1998. Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development. Proc. Natl. Acad. Sci. U. S. A 95(5):2343-2348

 

Quiring R, Walldorf U, Kloter U, Gehring WJ. 1994. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265(5173):785-789

 

Affolter M, Montagne J, Walldorf U, Groppe J, Kloter U, LaRosa M, Gehring WJ. 1994. The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development. Development 120(4):743-753

 

Affolter M, Walldorf U, Kloter U, Schier AF, Gehring WJ. 1993. Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers. Development 117(4):1199-1210

 

Walldorf U, Gehring WJ. 1992. Empty spiracles, a gap gene containing a homeobox involved in Drosophila head development. EMBO J. 11(6):2247-2259

 

Paterson BM, Shirakata M, Nakamura S, Dechesne C, Walldorf U, Eldridge J, Dubendorfer A, Frasch M, Gehring WJ. 1992. Isolation and functional comparison of Dmyd, the Drosophila homologue of the vertebrate myogenic determination genes, with CMD1. Symp. Soc. Exp. Biol. 46:89-109

 

Paterson BM, Walldorf U, Eldridge J, Dubendorfer A, Frasch M, Gehring WJ. 1991. The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells. Proc. Natl. Acad. Sci. U. S. A 88(9):3782-3786

 

Walldorf U, Hovemann BT. 1990. Apis mellifera cytoplasmic elongation factor 1 alpha (EF-1 alpha) is closely related to Drosophila melanogaster EF-1 alpha. FEBS Lett. 267(2):245-249

 

Walldorf U, Fleig R, Gehring WJ. 1989. Comparison of homeobox-containing genes of the honeybee and Drosophila. Proc. Natl. Acad. Sci. U. S. A 86(24):9971-9975

 

Shepherd JC, Walldorf U, Hug P, Gehring WJ. 1989. Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. Proc. Natl. Acad. Sci. U. S. A 86(19):7520-7521

 

Hovemann B, Richter S, Walldorf U, Cziepluch C. 1988. Two genes encode related cytoplasmic elongation factors 1 alpha (EF-1 alpha) in Drosophila melanogaster with continuous and stage specific expression. Nucleic Acids Res. 16(8):3175-3194

 

Ryseck RP, Walldorf U, Hoffmann T, Hovemann B. 1987. Heat shock loci 93D of Drosophila melanogaster and 48B of Drosophila hydei exhibit a common structural and transcriptional pattern. Nucleic Acids Res. 15(8):3317-3333

 

Ryseck RP, Walldorf U, Hovemann B. 1985. Two major RNA products are transcribed from heat-shock locus 93D of Drosophila melanogaster. Chromosoma 93(1):17-20

 

Walldorf U, Richter S, Ryseck RP, Steller H, Edstrom JE, Bautz EK, Hovemann B. 1984. Cloning of heat-shock locus 93D from Drosophila melanogaster. EMBO J. 3(11):2499-2504

 

Peters FP, Lubsen NH, Walldorf U, Moormann RJ, Hovemann B. 1984. The unusual structure of heat shock locus 2-48B in Drosophila hydei. Mol. Gen. Genet. 197(3):392-398

 

Hovemann B, Galler R, Walldorf U, Kupper H, Bautz EK. 1981. Vitellogenin in Drosophila melanogaster: sequence of the yolk protein I gene and its flanking regions. Nucleic Acids Res. 9(18):4721-4734