Medizinische Fakultät der Universität des Saarlandes
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Publications 2017 :



Publications 2016 :


Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry.

Dörr K, Kilch T, Kappel S, Alansary D, Schwär G, Niemeyer BA, Peinelt C.

Sci Signal. 2016 Mar 8;9(418):ra25.



Publications 2015 :


A STIM2 splice variant negatively regulates store-operated calcium entry.

Miederer AM, Alansary D, Schwär G, Lee PH, Jung M, Helms V, Niemeyer BA.

Nat Commun. 2015 Apr 21;6:6899. doi: 10.1038/ncomms7899.


Facilitation of Orai3 targeting and store-operated function by Orai1.

Alansary D, Bogeski I, Niemeyer BA.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2015 Mar; 1853(7):1541-1550.



Publications 2014 :


Patch-clamp measurement of ICRAC and ORAI channel activity.

Alansary D, Kilch T, Holzmann C, Peinelt C, Hoth M, Lis A.

Cold Spring Harb Protoc. 2014 Jun 2;2014(6):602-7. doi: 10.1101/pdb.top066795.


The minimal requirements to use calcium imaging to analyze ICRAC.

Alansary D, Kilch T, Holzmann C, Peinelt C, Hoth M, Lis A.

Cold Spring Harb Protoc. 2014 Jun 2;2014(6):638-42. doi: 10.1101/pdb.prot073262.


Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique.

Alansary D, Kilch T, Holzmann C, Peinelt C, Hoth M, Lis A.

Cold Spring Harb Protoc. 2014 Jun 2;2014(6):630-7. doi: 10.1101/pdb.prot073254.



Publications 2012 :


Kilch T, Alansary D, Peglow M, Doerr K, Rychkov G, Rieger H, Peinelt C, Niemeyer BA.

Mutations of the Ca2+-sensing Stromal Interaction Molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1

Journal of Biological Chemistry. 2012 Dec 04



Publications 2011 :


Quintana A, Pasche M, Junker C, Alansary D, Rieger H, Kummerow C, Nuñez L, Villalobos C, Meraner P, Becherer U, Rettig J, Niemeyer BA, Hoth M.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

The EMBO Journal advance online publication 16 August 2011; doi:10.1038/emboj.2011.289 Published online: 16 August 2011


Qu B, Alansary D, Kummerow C, Hoth M, Schwarz EC.

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance.

Cell Calcium. 2011 Jun 10. [Epub ahead of print]



Publications 2010 :


Bogeski I, Alansary D, Qu B, Niemeyer BA, Hoth M, Peinelt C.

Pharmacology of ORAI channels as a tool to understand their physiological functions.

Expert Review of Clinical Pharmacology (2010 May);3 (3):291-303.


Bogeski I, Kummerov C, Alansary D, Schwarz EC, Koehler R, Kozai D, Takahashi N, Peinelt C, Griesemer D, Bozem M, Mori Y, Hoth M, Niemeyer BA.

Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling.

Sci Signal. (2010 Mar 30);3 (115):ra24.


Alansary D, Bogeski I, Disteldorf BM, Becherer U, Niemeyer BA.

ATP modulates Ca2+ uptake by TRPV6 and is counteracted by isoform-specific phosphorylation.

FASEB J. (2010 Feb);24(2):425-35. Epub 2009 Oct 5.