Publications
Jaumann, M., Dettling, J., Gubelt, M., Zimmermann, U., Gerling, A., Paquet-Durand, F., Feil, S., Wolpert, S., Franz, C., Varakina, K., Xiong, H., Brandt, N., Kuhn, S., Geisler, H., Rohbock, K., Ruth, P., Schlossmann, J., Hütter, J., Sandner, P., Feil, R., Engel, J., Knipper, M., Rüttiger, L.
"cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function"
Nat. Med., 18, 252-259. (2012)
Buerbank, S., Becker, K., Becker, C., Brandt, N., Engel, J., Knipper, M., Schick, B., Dlugaiczyk, J.
"Developmental regulation of glycine receptors at efferent synapses of the murine cochlea"
Histochem. Cell Biol., 136, 387-398. (2011)
El Ouardi, A., Streckert, J., Bitz, A., Münkner, S., Engel, J., Hansen, V.
"New fin-line devices for radiofrequency exposure of small biological samples in vitro allowing whole-cell patch clamp recordings"
Bioelectromagnetics, 32, 102-112. (2011)
Baig, S. M. , Koschak, A., Lieb, A., Gebhart, M., Dafinger, C., Nürnberg, G., Ali, A., Ahmad, I., Sinnegger-Brauns, M. J. , Brandt, N., Engel, J., Mangoni, M. E. , Farooq, M., Khan, H. U. , Nürnberg, P., Striessnig, J., Bolz, H. J.
"Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness"
Nat. Neurosci., 14, 77-84. (2011)
Johnson, S. L. , Franz, C., Kuhn, S., Furness, D. N. , Rüttiger, L., Münkner, S., Rivolta, M. N. , Seward, E. P. , Herschman, H. R. , Engel, J., Knipper, M., Marcotti, W.
"Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses"
Nat. Neurosci., 13, 45-52. (2010)
Zampini, V., Johnson, S. L. , Franz, C., Lawrence, N. D. , Münkner, S., Engel, J., Knipper, M., Magistretti, J., Masetto, S., Marcotti, W.
"Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells"
J. Physiol. (Lond.), 588, 187-199. (2010)
Gebhart, M., Juhasz-Vedres, G., Zuccotti, A., Brandt, N., Engel, J., Trockenbacher, A., Kaur, G., Obermair, G. J. , Knipper, M., Koschak, A., Striessnig, J.
"Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule"
Mol. Cell. Neurosci., 44, 246-259. (2010)
Kuhn, S., Knirsch, M., Rüttiger, L., Kasperek, S., Winter, H., Freichel, M., Flockerzi, V., Knipper, M., Engel, J.
"Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4"
Channels (Austin), 3, 366-376. (2009)
Heidrych, P., Zimmermann, U., Kuhn, S., Franz, C., Engel, J., Duncker, S. V. , Hirt, B., Pusch, C. M. , Ruth, P., Pfister, M., Marcotti, W., Blin, N., Knipper, M.
"Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell"
Hum. Mol. Genet., 18, 2779-2790. (2009)
Winter, H., Rüttiger, L., Müller, M., Kuhn, S., Brandt, N., Zimmermann, U., Hirt, B., Bress, A., Sausbier, M., Conscience, A., Flamant, F., Tian, Y., Zuo, J., Pfister, M., Ruth, P., Löwenheim, H., Samarut, J., Engel, J., Knipper, M.
"Deafness in TRbeta mutants is caused by malformation of the tectorial membrane"
J. Neurosci., 29, 2581-2587. (2009)
Johnson, S. L. , Forge, A., Knipper, M., Münkner, S., Marcotti, W.
"Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses"
J. Neurosci., 28, 7670-7678. (2008)
Engel, J.
"Gerbils can tune in"
J. Physiol. (Lond.), 586, 919. (2008)
Singh, A., Gebhart, M., Fritsch, R., Sinnegger-Brauns, M. J. , Poggiani, C., Hoda, J., Engel, J., Romanin, C., Striessnig, J., Koschak, A.
"Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain"
J. Biol. Chem., 283, 20733-20744. (2008)
Tarabova, B., Lacinova, L., Engel, J.
"Effects of phenylalkylamines and benzothiazepines on Ca(v)1.3-mediated Ca2+ currents in neonatal mouse inner hair cells"
Eur. J. Pharmacol., 573, 39-48. (2007)
Knirsch, M., Brandt, N., Braig, C., Kuhn, S., Hirt, B., Münkner, S., Knipper, M., Engel, J.
"Persistence of Ca(v)1.3 Ca2+ channels in mature outer hair cells supports outer hair cell afferent signaling"
J. Neurosci., 27, 6442-6451. (2007)
Winter, H., Braig, C., Zimmermann, U., Engel, J., Rohbock, K., Knipper, M.
"Thyroid hormone receptor alpha1 is a critical regulator for the expression of ion channels during final differentiation of outer hair cells"
Histochem. Cell Biol., 128, 65-75. (2007)
Brandt, N., Kuhn, S., Münkner, S., Braig, C., Winter, H., Blin, N., Vonthein, R., Knipper, M., Engel, J.
"Thyroid hormone deficiency affects postnatal spiking activity and expression of Ca2+ and K+ channels in rodent inner hair cells"
J. Neurosci., 27, 3174-3186. (2007)
Schug, N., Braig, C., Zimmermann, U., Engel, J., Winter, H., Ruth, P., Blin, N., Pfister, M., Kalbacher, H., Knipper, M.
"Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat"
Eur. J. Neurosci., 24, 3372-3380. (2006)
Engel, J., Braig, C., Rüttiger, L., Kuhn, S., Zimmermann, U., Blin, N., Sausbier, M., Kalbacher, H., Münkner, S., Rohbock, K., Ruth, P., Winter, H., Knipper, M.
"Two classes of outer hair cells along the tonotopic axis of the cochlea"
Neuroscience, 143, 837-849. (2006)
Strutz-Seebohm, N., Seebohm, G., Fedorenko, O., Baltaev, R., Engel, J., Knirsch, M., Lang, F.
"Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes"
Cell. Physiol. Biochem., 18, 57-66. (2006)
Winter, H., Braig, C., Zimmermann, U., Geisler, H., Fränzer, J., Weber, T., Ley, M., Engel, J., Knirsch, M., Bauer, K., Christ, S., Walsh, E. J. , McGee, J., Köpschall, I., Rohbock, K., Knipper, M.
"Thyroid hormone receptors TRalpha1 and TRbeta differentially regulate gene expression of Kcnq4 and prestin during final differentiation of outer hair cells"
J. Cell. Sci., 119, 2975-2984. (2006)
Rüttiger, L., Sausbier, M., Zimmermann, U., Winter, H., Braig, C., Engel, J., Knirsch, M., Arntz, C., Langer, P., Hirt, B., Müller, M., Köpschall, I., Pfister, M., Münkner, S., Rohbock, K., Pfaff, I., Rüsch, A., Ruth, P., Knipper, M.
"Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss"
Proc. Natl. Acad. Sci. U.S.A., 101, 12922-12927. (2004)
Michna, M., Knirsch, M., Hoda, J., Muenkner, S., Langer, P., Platzer, J., Striessnig, J., Engel, J.
"Cav1.3 (alpha1D) Ca2+ currents in neonatal outer hair cells of mice"
J. Physiol. (Lond.), 553, 747-758. (2003)
Waka, N., Knipper, M., Engel, J.
"Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti"
Histol. Histopathol., 18, 1115-1123. (2003)
Engel, J., Michna, M., Platzer, J., Striessnig, J.
"Calcium channels in mouse hair cells: function, properties and pharmacology"
Adv. Otorhinolaryngol., 59, 35-41. (2002)
Koschak, A., Reimer, D., Huber, I., Grabner, M., Glossmann, H., Engel, J., Striessnig, J.
"alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages"
J. Biol. Chem., 276, 22100-22106. (2001)
Platzer, J., Engel, J., Schrott-Fischer, A., Stephan, K., Bova, S., Chen, H., Zheng, H., Striessnig, J.
"Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels"
Cell, 102, 89-97. (2000)
Engel, J., Schultens, H. A. , Schild, D.
"Small conductance potassium channels cause an activity-dependent spike frequency adaptation and make the transfer function of neurons logarithmic"
Biophys. J., 76, 1310-1319. (1999)
Althaus, H. H. , Hempel, R., Klöppner, S., Engel, J., Schmidt-Schultz, T., Kruska, L., Heumann, R.
"Nerve growth factor signal transduction in mature pig oligodendrocytes"
J. Neurosci. Res., 50, 729-742. (1997)
Engel, J., Rabba, J., Schild, D.
"A transient, RCK4-like K+ current in cultured Xenopus olfactory bulb neurons"
Pflugers Arch., 432, 845-852. (1996)
Jung, A., Lischka, F. W. , Engel, J., Schild, D.
"Sodium/calcium exchanger in olfactory receptor neurones of Xenopus laevis"
Neuroreport, 5, 1741-1744. (1994)
Engel, J., Althaus, H. H. , Kristjansson, G. I.
"NGF increases [Ca2+]i in regenerating mature oligodendroglial cells"
Neuroreport, 5, 397-400. (1994)
Engel, J., Donath, E.
"Osmotic lysis of chromaffin granules treated with the ionophores nigericin and A23187 in isotonic sucrose solution at low pH"
Biochim. Biophys. Acta, 1064, 155-161. (1991)
Engel, J., Pastushenko, V. F. , Richter, W., Donath, E.
"On the interaction between chromaffin granule membranes and intragranular vesicles--theory and analysis of freeze-fracture micrographs"
Biorheology, 28, 75-87. (1991)
Engel, J., Ermakov, Y. A. , Richter, W., Donath, E.
"Two different types of lysis of chromaffin granules characterised by freeze-fracture electron microscopy and photon correlation spectroscopy"
Biochim. Biophys. Acta, 1028, 236-244. (1990)
Engel, J., Donath, E., Ermakov, Y. A. , Meyer, H. W. , Richter, W.
"Hyperosmotic relaxation lysis of chromaffin granules is caused by interactions between the granular membrane and intragranular vesicles"
Biochim. Biophys. Acta, 985, 111-119. (1989)