| Zimmermann: Schlenstedt: Jung: Zimmermann
Veröffentlichungen zum Proteintransport: 1. Zimmermann, R. und Mollay, C. Import of honeybee prepromelittin into the endoplasmic reticulum: requirements for membrane insertion, processing and sequestration. (1986). J. Biol. Chem. 261, 12889-12895.
Impaktfaktor 2002: 6,696 2. Müller, G. und Zimmermann, R. Import of honeybee prepromelittin into the endoplasmic reticulum: structural basis for independence of SRP and docking protein. (1987). EMBO J. 6, 2099-2107.
Impaktfaktor 2002: 10,698 3. Wiech, H., Sagstetter, M., Müller, G. und Zimmermann, R. The ATP requiring step in assembly of M 13 procoat protein into microsomes is related to preservation of transport competence of the precursor protein. (1987). EMBO J. 6, 1011-1016.
Impaktfaktor 2002: 10,698 4. Schlenstedt, G. und Zimmermann, R. Import of frog prepropeptide GLa into microsomes requires ATP but does not involve docking protein or ribosomes. (1987). EMBO J. 6, 699-703.
Impaktfaktor 2002: 10,698 5. Sagstetter, M. und Zimmermann, R. Assembly of M 13 and M 13 am8H1R1 procoat protein into microsomes is stimulated by rabbit reticulocyte lysate and ATP. (1988). Biochem. Biophys. Res. Comm. 153, 498-501.
Impaktfaktor 2002: 2,935 6. Müller, G. und Zimmermann, R. Import of honeybee prepromelittin into the endoplasmic reticulum: energy requirements for membrane insertion. (1988). EMBO J. 7, 639-648.
Impaktfaktor 2002: 10,698 7. Zimmermann, R., Sagstetter, M., Lewis, M.J. und Pelham, H.R.B. Seventy-kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M 13 procoat protein into microsomes. (1988). EMBO J. 7, 2875-2880.
Impaktfaktor 2002: 10,698 8. Cobet, W., Mollay, C., Müller, G. und Zimmermann, R. Export of honeybee prepromelittin in E.coli depends on the membrane potential but does not depend on proteins secA and secY. (1989). J. Biol. Chem. 264, 10169-10176.
Impaktfaktor 2002: 6,696 9. Boman, H.G., Boman, A., Andrue, D. Li, Z., Merrifield, R.B. Schlenstedt, G. und Zimmermann, R. Chemical synthesis and enzyme processing of precursor forms of cecropin A and B. (1989). J. Biol. Chem. 264, 5852-5860.
Impaktfaktor 2002: 6,696 10. Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. und Zimmermann, R. A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosomes, and posttranslationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes. (1990). J. Biol. Chem. 265, 13960-13968.
Impaktfaktor 2002: 6,696 11. Zimmermann, R., Sagstetter, M. und Schlenstedt, G. Ribonuleoparticle-independent import of proteins into mammalian microsomes involves a membrane protein which is sensitive to chemical alkylation. (1990). Biochimie 72, 95-101.
Impaktfaktor 2002: 3,303 12. Klappa, P., Mayinger, P., Pipkorn, R., Zimmermann, M. und Zimmermann, R. A microsomal protein is involved in ATP-dependent transport of presecretory proteins into mammalian microsomes. (1991). EMBO J. 10, 2795-2803.
Impaktfaktor 2002: 10,696 13. Zimmermann, R., Zimmermann, M., Mayinger, P. und Klappa, P. Photoaffinity labeling of mammalian microsomes with azido-ATP affects association of nascent presecretory proteins with the signal sequence receptor complex. (1991). FEBS Lett. 285, 95-99.
Impaktfaktor 2002: 3,912 14. Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. und Zimmermann, R. Structural requirements for transport of preprocecropinA and related presecretory proteins into mammalian microsomes. (1992). J. Biol. Chem. 267, 24328-24332.
Impaktfaktor 2002: 6,696 15. Wiech, H., Buchner, J., Zimmermann, M., Zimmermann, R. und Jakob, U. Hsc70, BiP and Hsp90 differ in their ability to stimulate transport of precursor proteins into mammalian microsomes. (1993). J. Biol. Chem. 268, 7414-7421.
Impaktfaktor 2002: 6,696 16. Schlenstedt, G., Zimmermann, M. und Zimmermann, R. A stably folded presecretory protein associates with and upon unfolding translocates across the membrane of mammalian microsomes. (1994). FEBS Lett. 340, 139-144.
Impaktfaktor 2002: 3,912 17. Klappa, P., Zimmermann, M. und Zimmermann, R. The membrane proteins TRAMp and sec61ap may be involved in postranslational transport of presecretory proteins into mammalian microsmes. (1994). FEBS Lett. 341, 281-287.
Impaktfaktor 2002: 3,912 18. Jung, C. und Zimmermann, R. The relationship between size of a presecretory protein and extent of signal recognition particle mediated arrest of its translation. (1994). Biochem. Biophys. Res. Commun. 205, 603-611.
Impaktfaktor 2002: 2,935 19. Klappa, P., Freedman, R.B. und Zimmermann, R. Protein disulphide isomerase and a lumenal cyclphilin-type peptidyl prolyl cis-trans isomerase are in transient contact with secretory proteins during late stages of translocation. (1995). Eur. J. Biochem. 232, 755-764.
Impaktfaktor 2002: 2,999 20. Brunke, M., Tyedmers, J. und Zimmermann, R. Protein folding within and protein transport into dog pancreas microsomes are differentially affected by photoaffinity labeling of microsomes with 8-azido-ATP. (1996). Biochem. Biophys. Res. Commun. 218, 454-460.
Impaktfaktor 2002: 2,935 21. Dierks, T., Volkmer, J., Schlenstedt, G., Jung, C., Sandholzer, U., Zachmann, K., Schlotterhose, P., Neifer, K., Schmidt, B. und Zimmermann, R. A microsomal ATP-binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum. (1996). EMBO J. 15, 6931-6942.
Impaktfaktor 2002: 10,696 22. Volkmer, J., Guth, S., Nastainczyk, W., Knippel, P., Klappa, P., Gnau, V. und Zimmermann, R. Pancreas-specific protein disulfide isomerase, PDIp, is in transient contact with secretory proteins during late stages of translocation. (1997). FEBS Lett. 406, 291-295.
Impaktfaktor 2002: 3,912 23. Elliott, J.G., Oliver, J.D., Volkmer, J., Zimmermann, R. und High, S. In vitro characterization of the interaction between newly synthesized proteins and a pancreatic isoform of protein disulfide isomerase. (1998). Eur. J. Biochem. 252, 372-377.
Impaktfaktor 2002: 2,999 24. Moeller, I., Jung, M., Beatrix, B., Levy, R., Kreibich, G., Zimmermann, R., Wiedmann, M. und Lauring, B. A general mechanism for regulation of access to the translocon: Competition for a membrane attachment site on ribosomes. (1998). Proc. Natl. Acad. Sci. USA 95, 13425-13430.
Impaktfaktor 2002: 10,70 25. Bies, C., Guth, S., Janoschek, K., Nastainczyk, W., Volkmer, J. und Zimmermann, R. A Scj1p homolog and folding catalysts present in dog pancreas microsomes. (1999). Biol. Chem. 380, 1175-1182.
Impaktfaktor 2002: 2,548 26. Tyedmers, J., Lerner, M., Bies, C., Dudek, J., Skowronek, M., Haas, I., Heim, N., Nastainczyk, W., Volkmer, J. und Zimmermann, R. Homologs of yeast transport proteins Sec62p and Sec63p are abundant proteins in the dog pancreas microsomes. (2000). Proc. Natl. Acad. Sci. USA 97, 7214-7219.
Impaktfaktor 2002: 10,70 27. Faust, M., Jung, M., Günther, J., Zimmermann, R. und Montenarh, M. Localization of individual subunits of protein kinase CK2 to the endoplasmic reticulum and to the Golgi apparatus. (2001). Mol. Cell. Biochem. 227, 73-80.
Impaktfaktor 2002: 1,548 28. Dudek, J., Volkmer, J., Bies, C., Guth, S., Müller, A., Lerner, M., Feick, P., Schäfer, K.-H., Morgenstern, E., Hennessy, F., Blatch, G. L., Janoscheck, K., Heim, N., Frien, M., Nastainczyk, W. und Zimmermann, R. A novel type of cochaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomes. (2002). EMBO J. 21, 2958-2967.
Impaktfaktor 2002: 10,696 29. Abell, B.M., Jung, M., Oliver, J.D., Knight, B.C., Tyedmers, J., Zimmermann, R. und High, S. Tail-anchored and signal-anchored proteins utilise overlapping pathways during membrane insertion. (2003). J. Biol. Chem. 278, 5669-5678.
Impaktfaktor 2002: 6,696 30. Fehrmann, F., Jung, M., Zimmerann, R. und Kräusslich, H.-G. Transport of MIA polyprotein to the endoplasmic reticulum is mediated by SRP. (2003). J. Virol. 77, 6239-6304.
Impaktfaktor 2002: 5,24 31. Tyedmers, J., Lerner, M., Wiedmann, M., Volkmer, J. und Zimmermann, R. Polypeptide chain binding proteins mediate completion of cotranslational protein translocation into the mammalian endoplasmic reticulum. (2003). EMBO reports 4, 505-510.
Impaktfaktor 2002: 7,698 32. Wirth, A., Jung, M., Bies, C., Frien, M., Tyedmers, J. und Zimmermann, R. The Sec61p complex is a dynamic precursor activated channel. (2003). Mol. Cell 12, 261-268.
Impaktfaktor 2002: 16,471 33. Bies, C., Blum, R., Dudek, J., Nastainczyk, W., Oberhauser, S., Jung, M. und Zimmermann, R. Characterization of pancreatic ERj3p, a homolog of yeast DnaJ-like protein Scj1p. (2004). Biol. Chem. 385, 389-395.
Impaktfaktor 2002: 2,548 34. Guth, S., Völzing, C., Müller, A., Lerner, M., Jung, M. und Zimmermann, R. Protein transport into canine pancreatic microsomes: a quantitative approach. (2004). Eur. J. Biochem. 271, 3200-3207.
Impaktfaktor 2002: 2,999 35. Tyedmers, J., Lerner, M., Nastainczyk, W. und Zimmermann, R. Calumenin and reticulocalbin are associated with the protein translocase of the mammalian endoplasmic reticulum. (2005). J. Biol. Sci. 5, 70-75. 36. Dudek, J., Greiner, M., Müller, A., Hendershot, L.M., Kopsch, K., Nastainczyk, W. und Zimmermann, R. (2005) ERj1p has a basic role in protein biogenesis at the endoplasmic reticulum, Nat. Struct. Mol. Biol. 12, 1008-1014.
Impaktfaktor 2003:11,579 37. Blau, M., Mullapudi, S., Becker, T., Dudek, J., Zimmermann, R., Penczek, P. A. und Beckmann, R. (2005) ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the mebrane, Nat. Struct. Mol. Biol. 12, 1015-1016.
Impaktfaktor 2003: 11,579
38. Dudek, J., Diaz de Escauriaza, M., Müller, A., Nastainczyk, W., Scholtes, P. und Zimmermann, R. (2006) Signal recognition particle mediated arrest of translation involves competition with eEF2 on the ribosome, J. Biol. Sci. 6, 316-319. 39. Weitzmann A., Baldes, C., Dudek, J. und Zimmermann, R.(2007) The Hsp70-molecular chaperone network in the pancreatic endoplasmic reticulum: a quantitative approach, FEBS J. 274, 5175-5187.
Impaktfaktor 2002: 2,999 40. Zahedi, R. P., Völzing, C., Schmitt, A., Frien, M., Jung, M., Dudek, J., Wortelkamp, S., Sickmann, A. und Zimmermann, R. (2009) Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7, Proteomics 9, 3463-3473.
Impaktfaktor 2007: 5,479
41. Erdmann, F., Jung, M., Eyrisch, S., Lang, S., Helms, V., Wagner, R. und Zimmermann, R. (2009) Lanthanum inhibits the mammalian Sec61 complex in its channel dynamics and protein transport activity, FEBS Lett., 583,2359-2364
Impaktfaktor 2004: 3,912 42. Götz, C., Müller, A., Montenarh, M., Zimmermann, R. und Dudek, J. (2009) ERj1 is a substrate of phosphorylation by CK2, Biochem. Biophys. Res. Commun. 388,637-642. Impaktfaktor 2008: 2,648 43. Müller, L., Diaz de Escauriaza, M., Lajoie, P., Theis, M., Jung, M., Müller, A., Burgard, C., Greiner, M., Snapp E. L., Dudek, J. und Zimmermann, R. (2010) Evolutionary gain of function of the ER membrane protein Sec62 from yeast to humans, Mol. Biol. Cell 21, 691-703. Impaktfaktor 2008: 5,558 44. Erdmann, F., Jung, M., Maurer, P., Harsman, A., Zimmermann, R und Wagner, R. (2010) The mammalian and yeast translocon complexes comprise a characteristic Sec61 channel, Biochem. Biophys. Res. Commun. 396, 714-720. Impaktfaktor 2009: 2,548 45. Benedix, J., Lajoie, P., Jaiswal, H., Burgard, C., Greiner, M., Zimmermann, R., Rospert, S., Snapp, E.L. und Dudek, J. (2010) BiP modulates the affinity of its co-chaperone ERj1 to ribosomes , J. Biol. Chem. 285, 36427-36433. Impaktfaktor 2009: 5,328 46. Meissner, M., Obmann, V.C., Hoschke, M., Link, S., Jung, M., Held, G., Philipp, S.E., Zimmermann, R. und Flockerzi, V. (2010) Lessons of studying TRP channels wih antibodies, in TRP channels, CRC methods in signal transduction series (M.X. Zhu, ed.) CRC Press, New York, 135-148 (2011). 47. Ott, M., Tascher, G., Haßdenteufel, S., Zimmermann, R., Haas, J. und Bailer, S.M.(2011) "Functional charakterization of the essential tail-anchor of the HSV-1 nuclear egress protein UL34". J. Gen. Virol 92, 2734-2745. Impaktfaktor 2010: 3,568 48. Haßdenteufel, S., Schäuble, N., Cassella, P., Leznicke, P., Müller, A., High, S., Jung, M. und Zimmermann, R. (2011) "Calcium-calmodulin inhibits tail-anchored protein insertion into the mamalian endoplasmic reticulum membrane", FEBS Lett. 585, 3485-3490. Impaktfaktor 2009: 3,263 49. Lang, S., Benedix, J., Fedeles, S.V., Schorr, S., Schirra, C., Schäuble, N., Jalal, C., Greiner, M., Haßdenteufel, Sl, Tatzelt, J., Kreutzer, B., Edelmann, L., Krause, E., Rettig J., Somlo, S., Zimmermann, R., und Dudek, J. (2012) "Differential effects of Sec61a-, Sec62 and Sec63-depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells", J.Cell Sci., in press Impaktfaktor 2009: 6,29 Zimmermann Veröffentlichungen zur Calcium-Homöostase 1.*Erdmann, F., *Schäuble, N., Lang, S., Jung, M., Honigmann, A., Ahmad, M., Benedix, J., Dudek, J., Kopp, A., Helms, V., #Cavalie, A., #Wagner, R. und #Zimmermann, R. (2010) Interaction of calmodulin with Sec61a limits Ca²+ leakage from the endoplasmic reticulum, EMBO J. 30,17-31. *equal contribution, #corresponding authors Impaktfaktor 2009: 8,993 2. Lang, S., Erdmann, F., Jung, M., Wagner, R., Cavalié, A. und Zimmermann, R. (2011) Sec 61 complexes form ubiquitous ER Ca2+ leak channels, Channels 5, 228-235. Impaktfaktor 2010: 2,103 3. Lang, S., Schäuble, N., Cavalié, A. und Zimmermann, R. (2011) Live cell calcium imaging in combination with siRNA mediated gene silencing identifies Ca2+ leak channels in the ER membrane and theis regulatory mechanisms, J. Visualized Experiments DOI: 10.3791/2730. 4. Harsman, A., Kopp, A., Wagner, R., Zimmermann, R. und Jung, M. (2011), Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates, Channels 5, 293-298. Impaktfaktor 2010: 2,103 Zimmermann Veröffentlichungen zu medizinischen Aspekten 1. Jung, V., Kamradt, J., Kindich, R., Jung, M., Müller, M., Schulz, W.A., Engers, R., Stöckle, M., Zimmermann, R. und Wullich B. (2006) "Genomic and expression analysis of the 3q25-q26 amplication unit reveals TLOC1/SEC62 as a problable target gene in prostate cancer", Mol. Cancer Res. 4:,169-176. Impaktfaktor 2004: 4,81
2. Weitzmann, A., Volkmer, J. und Zimmermann, R. (2006) The nucleotide exchange factor activity of Grp170 may explain the non-lethal phenotype of loss of Sil1 function in man and mouse, FEBS Lett. 580: 5237-5240.
Impaktfaktor 2002: 3,912 3. Greiner, M., Kreutzer, B., Jung, V., Grobholz, R., Hasenfus, A., Stöhr, R., Franz, R., Tornillo, L., Dudek, J., Stöckle, M., Unteregger, G., Kamradt, J., Wullich, B. und Zimmermann, R. (2010) Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells, Int. J. Cancer 128, 2284-2295. Impaktfaktor 2009: 4,722 4. Greiner, M., Kreutzer, B., Jung, V., Cavalié, A., Unteregger, G. , Zimmermann, R. and Wullich, B. (2010) Sec62 protein level is crucial for ER-stress tolerance of prostate cancer. The Prostate71, 1074-1083. Impaktfaktor 2009: 3,081 5. Müller, L., Funato Y., Miki, H. and Zimmermann, R. (2010) An interaction between human Sec63 with nucleoredoxin may provide the missing link between the SEC63 gene and polycystic liver disease, FEBS Lett. 585, 596-600. 6. *Linxweiler, M., *Linxweiler, J., Barth, M., Benedix, J., Jung, V., Kim, Y.-J., Bohle, R., Zimmermann, R. und Greiner, M. (2012) "Sec62 bridges the gap from 3q amplification to molecular cell biology in NSCLC", Am.J. Pathol. 180, 473-483. *equal contribution Impaktfaktor 2010:5,224 Zimmermann
Veröffentlichungen zur Proteinfaltung: 1. Wiech, H., Buchner, J., Zimmermann, R. und Jakob, U. Hsp90 chaperones protein folding in vitro. (1992). Nature 358, 169-170.
Impaktfaktor 2002: 30,43 2. Kruse, M., Brunke, M., Escher, A., Szalay, A.A., Tropschug, M. und Zimmermann, R. Enzyme assembly after de novo synthesis in rabbit reticulocyte lysates involves molecular chaperones and immunophilins. (1995). J. Biol. Chem. 270, 2588-2594.
Impaktfaktor 2002: 6,696 3. Brunke, M., Dierks, T., Schlotterhose, P., Escher, A., Schmidt, B., Szalay, A. A., Lechte, M., Sandholzer, U. und Zimmermann, R. Luciferase assembly after transport into mammalian microsomes involves molecular chaperones and peptidylprolyl cis/trans isomerases (1996). J. Biol. Chem. 271, 23487-23494.
Impaktfaktor 2002: 6,696 4. Tyedmers, J., Brunke, M., Lechte, M., Sandholzer, U., Dierks, T., Schlotterhose, P., Schmidt, B. und Zimmermann, R. Efficient folding of firefly luciferase after transport into mammalian microsomes in the absence of lumenal chaperones and folding catalysts. (1996) . J. Biol. Chem. 271, 19509-19513.
Impaktfaktor 2002: 6,696 5. Klappa, p., Stromer, T., Zimmermann, R., Ruddock, L.W. und Freedman, R.B. A pancreas-specific glycosylated protein disulfide-isomerase binds to misfolded proteins and peptides with an interaction inhibited by oestrogens. (1998). Eur. J. Biochem. 254, 63-69.
Impaktfaktor 2002: 2,999 6. Lüders, J., Demand, J., Schönfelder, S., Frien, M., Zimmermann, R. und Höhfeld, J. Cofactor-induced modulation of the functional specificity of the molecular chaperon Hsc70. (1998). Biol. Chem. 379, 1217-1226.
Impaktfaktor 2002: 2,548 7. Tyedmers, J., Kruse, M., Lerner, M., Demand, J., Höhfeld, J., Solsbacher, J., Volkmer, J. und Zimmermann, R. Assembly of heterodimeric luciferase after de novo synthesis in rabbit reticulocyte lysate involves Hsc70 and Hsp40 at a posttranslational stage. (2000). Eur. J. Biochem. 267, 3575-3582.
Impaktfaktor 2002: 2,999 8. Odunuga, O. O., Hornby, J. A., Bies, C., Zimmermann, R., Pugh, D. J. und Blatch, G. L. Tetratricopeptide repeat motif-mediated Hsc70-mSTI1 interaction: molecular characterization of the critical contacts for successful binding and specificity. (2003). J. Biol. Chem. 278, 6896-6904.
Impaktfaktor 2002: 6,696 9. Nicoll, W. S., Botha, M., McNamara, C., Schlange, M., Pesce, E.-R., Boshoff, A., Ludewig, M. H., Zimmermann, R., Cheetham, M. E., Chapple, J. P. und Blatch, G. L. (2007) Cytoslic and ER J-domains of mammalian and parasitic origin can functionally interact with DnaK, Int. J. Biochem. Cell Biol. 39, 736-751.
Impaktfaktor 2004: 3,578
Zimmermann Veröffentlichungen zu Export und Degradation von Proteinen: Klappa, P., Dierks, T. und Zimmermann, R. Cyclosporin A inhibits thedegradation of sig nal sequences after processing of presecretory proteins by signal peptidase. (1996). Eur. J. Biochem. 239, 509-518.
Impaktfaktor 2002: 2,999
Zimmermann
Übersichtsartikel und Buchbeiträge: 1. Zimmermann, R. und Meyer, D.I. (1986) 1986: A year of new insights into how proteins cross membranes, Trends in Biochem. Sci. 11, 512-515.
Impaktfaktor 2002: 14,398 2. Zimmermann, R., Sagstetter, M., Schlenstedt, G., Wiech, H., Kaßeckert, B. und Müller, G. (1988) Import of small secretory and plasma membrane proteins into the endoplasmic reticulum, in "Membrane Biogenesis" (Op den Kamp, J.A.F., ed.) Springer Verlag, Berlin-Heidelberg, 337-350. 3. Müller, G., Schlenstedt, G., Wiech, H. und Zimmermann, R. (1988) Import of proteins into the endoplasmic reticulum, Biochemical Society Transactions 16, 708-709.
Impaktfaktor 2002: 2,205 4. Müller, G. und Zimmermann, R. (1988) Import of honeybee prepromelittin into the endoplasmic reticulum, in "Gene Expression and Regulation" (Bissell, M. et al., eds) Elsevier Science Publishers B.V., Amsterdam, 199-208. 5. Schlenstedt, G., Cobet, W.W.E., Wiech, H. und Zimmermann, R. (1989) Mechanisms of protein import into the endoplasmic reticulum and protein export in E. coli, Biochemical Society Transactions 17, 822-823.
Impaktfaktor 2002: 2,205 6. Schlenstedt, G., Wachter, E., Sagstetter, M., Morel, F., Zimmermann, R., Gudmundsson, G.H. und Boman, H.G. (1990) Import of preprocecropin A and related precursor proteins into the endoplasmic reticulum, in "Dynamics and Biogenesis of Membranes" (Op den Kamp, J.A.F., ed.) Springer Verlag, Berlin-Heidelberg, 311-326. 7. Wiech, H. Stuart, R. und Zimmermann, R. (1990) Role of cytosolic factors in the transport of proteins across membranes, Seminars in Cell Biology 1, 55-64. 8. Zimmermann, R., Zimmermann, M., Wiech, H., Schlenstedt, G., Müller, G., Morel, F., Klappa, P., Jung, C. und Cobet, W.W.E (1990) Ribonuleoparticle-independent transport of proteins into mammalian microsomes, J. Bioenergetics and Biomembranes 22, 711-723. 9. Wiech, H., Klappa, P. und Zimmermann, R. (1991) Protein export in prokaryotes and eukaryotes: Theme with variations, FEBS Lett. 285, 182-188.
Impaktfaktor 2002: 3,912 10. Klappa, P., Müller, G., Schlenstedt, G., Wiech, H. und Zimmermann, R. (1992) Consecutive steps of nucleoside triphosphate-hydrolysis are driving transport of precursor proteins into the endoplasmic reticulum, New Comprehensive Biochemistry 22, 137-146. 11. Wiech, H. und Zimmermann, R. (1993) Role of molecular chaperones in transport of proteins into the mammalian endoplasmic reticulum, in "Protein Folding: in vivo and in vitro" (Cleland, J.L., ed.) American Chemical Society Symposium Series 526, Washington, 84-101. 12. Klappa, P., Zimmermann, M., Dierks, T. und Zimmermann, R. (1993) Components and mechanisms involved in transport of proteins into the endoplasmic reticulum, Subcellular Biochemistry 21, 17-40. 13. Dierks, T., Klappa, P., Wiech, H. und Zimmermann, R. (1993) Role of molecular chaperones in protein transport into the endoplasmic reticulum, Philosophical Transactions of the Royal Society 339, 335-341. 14. Dierks, T., Klappa, P., Wiech, H. und Zimmermann, R. (1993) Role of molecular chaperones in protein transport into the endoplasmic reticulum, in "Molecular Chaperones" (Ellis, R.J., Laskey, R.A. und Lorimer, G.H., eds) Chapman and Hall, London-New York, 79-85. 15. Zimmermann, M. und Zimmermann, R. (1994) Incorporation of biotinylated lysine into nascent polypeptides does not interfere with protein folding and protein transport, Boehringer Mannheim Biochemica 11, 25-27. 16. Hoeltke, H.-J., Ettl, I., Strobel, E., Leying, H., Zimmermann, M. und Zimmermann, R. (1995) Biotin in vitro translation, nonradioactive detection of cell-free synthesized proteins, Biotechniques 18, 900- 903.
Impaktfaktor 2002: 2,173 17. Hoeltke, H.-J., Ettl, I., Strobel, E., Leying, H., Zimmermann, M. und Zimmermann, R. (1996) Biotin in vitro translation, a nonradioactive method for the synthesis of biotin-labeled proteins in vitro: protocol and applications, in "BioMethods: A Laboratory Guide to Biotin- Labeling in Biomolecule Analysis" (T. Meier and F. Fahrenholz, eds), Birkhäuser, Basel, 183-199. 18. Zimmermann, R. (1998) The role of molecular chaperones in protein transport into the mammalian endoplasmic reticulum, Biol. Chem. 379, 275-282.
Impaktfaktor 2002: 2,548 19. Haas, I. und Zimmermann, R. (1999) Protein transport into and folding within the endoplasmic reticulum, in Molecular Biology of Chaperones and Folding Catalysts (B. Bukau, ed.) Harwood Academic Publishers, 205-233. 20. Jung, M., Bies, C., Dudek, J., Frien, M., Guth, S., Tyedmers, J. und Zimmermann, R. (2003) Multiple roles of molecular chaperones in protein transport into the mammalian endoplasmic reticulum, Signpost reviews, recent research developments in Molecular & Cellular Biology 3, 549-562. 21. Frien, M., Jung, M., Völzing, C. und Zimmermann, R. (2003) The rough endoplasmic reticulum: a proteomic analysis, Research Signpost, recent research developments in Biochemistry, 4, 113-124. 22. Maurer, P., Moratzky, A., Fecher-Trost, C., Flockerzi, V., Lenk, U., Sommer, T., Völzing, C. und Zimmermann, R. (2003) Cell-free synthesis of membrane proteins on a preparative scale, in Cell-free protein expression (J. R. Swartz ed.) Springer Verlag, Heidelberg, 133-139. 23. Hennessy, F., Zimmermann, R., Cheetham, M.E. und Blatch, G.L. (2005) Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactions, Prot. Sci. 14, 1697-1709.
Impaktfaktor 2002: 3,546 24. Flockerzi, V., Aberle, T., Meissner, M., Freichel, M., Philipp, S., Nastainczyl, W., Maurer, P. und Zimmermann, R. (2005) Specific detection and semi quantitative analysis of TRPC4 protein expression by antibodies, Pflügers Archiv. Europ. J. Physiol. 451, 81-86.
Impaktfaktor 2002: 2,036 25. Dudek, J., Jung, M., Weitzmann, A., Greiner, M. und Zimmermann, R. (2006) Co-chaperones of the endoplasmic reticulum, in The networking of chaperones by co-chaperones (G. Blatch, ed.) Landes Bioscience, 88-98. 26. Zimmermann, R., Müller, L. und Wullich, B. (2006) Protein transport into the endoplasmic reticulum: mechanisms and pathologies, Trends in Molecular Medicine 12, 567-573.
Impaktfaktor 2004: 7,497
27. Dudek, J., Benedix, J., Cappel, S., Greiner, M., Jalal, C., Müller, L. und Zimmermann, R. (2009) Functions and pathologies of BiP and its interaction partners. Cell. Mol. Life Sci. 65, 1556-1569.
Impaktfaktor 2007: 5,239
28. Zimmermann, R. und Blatch, G.L. (2009) A novel twist to protein secretion in eukaryotes, Trends in Parasitology 25, 147-150.
Impaktfaktor 2006: 4,9 29. Müller, L., Wullich, B. und Zimmermann, R. (2009). "Pathologies of protein transport into the endoplasmic reticulum". In: "Protein transport into the endoplasmic reticulum." (Zimmermann, R., ed.), Landes Bioscience, 102-109. 30. Zimmermann, R. (2009) Protein transport into the endoplasmic reticulum, Landes Bioscience. 31. Zimmermann, R., Eyrisch, S., Ahmad, M. und Helms, V. (2010) Protein translocation across the ER membrane, Biochim, Biophys. Acta, 1808,912-924. Impaktfaktor 2009: 3,998 Schlenstedt
Veröffentlichungen zum Kerntransport 1. Schlenstedt, G., Saavedra, C., Loeb, J.D.J., Cole, C.N. and Silver, P.A. (1995) The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly (A)+ RNA in the cytoplasm, Proc. Natl. Acad. Sci. USA 92, 225-229.
Impaktfaktor 2002: 10,70 2. Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P.A. and Fink, G.R. (1995) The yeast nuclear import receptor is required for mitosis, Proc. Natl. Acad. Sci. USA 92, 7647-7651.
Impaktfaktor 2002: 10,70 3. Corbett, A.H., Koepp, D.M., Schlenstedt, G., Lee, M.S., Hopper, A.K. and Silver, P.A. (1995) Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import, J. Cell Biol. 130, 1017-1026.
Impaktfaktor 2002: 12,522 4. Schlenstedt, G., Wong, D.H., Koepp, D.M. and Silver, P.A. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport, EMBO J. 14, 5367-5378.
Impaktfaktor 2002: 10,698 5. Schlenstedt, G., Smirnova, E., Deane, R., Solsbacher, J., Kutay, U., Görlich, D., Ponstingl, H. and Bischoff, F.R. (1997) Yrb4p, a yeast Ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus, EMBO J. 16, 6237-6249.
Impaktfaktor 2002: 10,698 6. Solsbacher, J., Maurer, P., Bischoff, F.R. and Schlenstedt, G. (1998) Cse1p is involved in export of yeast importin a from the nucleus, Mol. Cell. Biol. 18, 6805-6815.
Impaktfaktor 2002: 8,84 7. Solsbacher, J., Maurer, P., Vogel, F. and Schlenstedt, G. (2000) Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin a. Mol. Cell. Biol. 20, 8468-8479.
Impaktfaktor 2002: 8,84 8. Maurer, P., Redd, M., Solsbacher, J., Bischoff, F.R., Greiner, M., Podtelejnikov, A.V., Mann, M., Stade, K., Weis, K. and Schlenstedt, G. (2001) The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p). Mol. Biol. Cell 12, 539-549.
Impaktfaktor 2003: 7,599 9. Betz, C., Schlenstedt, G. und Bailer, S.M. (2004) Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus. J. Biol. Chem. 279, 28174-28181.
Impaktfaktor 2002: 6,696 10. Greiner, M., Caesar, S. und Schlenstedt, G. (2004) The histones H2A/H2B and H3/H4 are imported into the yeast nucleus by different mechanisms. Eur J. Cell Biol. 83, 511-520.
Impaktfaktor 2002: 2,441 11. Cook, A., Fernandez, E., Lindner, D., Ebert, J., Schlenstedt, G. und Conti, E. (2005) The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Mol. Cell 18, 355-367.
Impaktfaktor 2002: 16,471 12. Caesar, S., Greiner, M. and Schlenstedt, G. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast, Mol. Cell. Biol. 26, 3170-3180.
Impaktfaktor 2002: 8,84 13. Bakhrat, A., Baranes, K., Krichevsky, O., Rom, I., Schlenstedt, G., Pietrokovski, S. and Raveh, D. (2006) Nuclear import of Ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system. J. Biol. Chem. 281,12218-12226.
Impaktfaktor 2002: 6,696 14. Fries, T., Betz, C. Sohn, K., Caesar, S., Schlenstedt, G. and Bailer, S.M. (2007) Anovel conserved nuclear localization signal is recognized by a group of yeast importins. J. Biol. Chem. 282, 19292- 19301. Impaktfaktor 2202: 6,696 15. Hahn, S., Maurer, P., Caesar, S. and Schlenstedt, G. (2008) Classical NLS proteins from Saccharomyces cerevisae. J. Mol. Biol. 379, 678-694. Impaktfaktor 2009: 4,008 16. Neuber, A., Franke, J., Wittstruck, A., Schlenstedt, G., Sommer, T. and Stadt, K. (2008). The nuclear export reseptor Xpo1/Cm1 is physically and functionally linked to the spindle pole body in budding yeast. Mol. Cell Biol. 28, 5348-5358. Impaktfaktor 2002: 8,84 17. Kim, K.-Y., Truman, A.W., Caesar, S., Schlenstedt, G. and Levin, D.E. (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleoplasmic shuttling of the Qwi6 transcriptional regulator. Mol. Biol. Bell 21, 1609-1619. Impaktfaktor 2003:7,599 18. Chang, Y., Schlenstedt, G., Flockerzi, V. and Beck, A. (2010) Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1. FEBS Lett. 584, 2028-2032. Impaktfaktor 2002: 3,912 19. Hahn, S., and Schlenstedt, G. (2011). Importin ß-type nuclear transport receptors have distincts binding affinities for Ran-GTP. Biochem. Biophys.REs. Commun. 406, 383-388. Impaktfaktor 2009: 2,548 Jung 1. Jung, M., Just, I., van Damme, J., Vanderkerckhove, J. and Aktories, K. (1993) NAD-binding site of the C3-like ADP-ribosyltansferase from Clostridium limiosum. J.Biol. Chem. 268, 23215-23218. Impaktfaktor 2010: 5,328 2. Just, I., Sehr, P., Jung, M., vand Damme, J., Puype, M., Vandekerckhove, J., Moss, J. and Aktories, K. (1995) ADP-ribosyltransferase type A from turkey erythrocytes modifies actin at Arg-95 and Arg-372. Biochem. 34, 326-333. Impaktfaktor 2010: 3,226 3. Just, I., Selzer, J., Jung, M., van Damme, J., Vanderkerckhove J. and Aktories, K..(1995). Rho-ADP-ribosylating exoenzyme from Bacillus cereus. Purification, characterization and identification ot the NAD-binding site. Biochem. 34, 334-340. Impaktfaktor 2010: 3,226 4. Aktories, K., Jung, M., Böhmer, J., Fritz, G., Vanderkerckhove, J. and Just, I. (1995) Studies on the active-site structure of C3-like exoenzymes: involvement of glutamic acid in catalysis of ADP-ribosylation. Biochimie 77, 326-332. Impaktfaktor 2010: 3,787 5. Böhmer, J., Jung, M. Sehr, P., Fritz, G., Popoff, M., Just, I. and Aktories, K. (1996) Active site mutation of the C3-like ADP-ribosyltransferase from C. limosum - Analysis of glutamic acid 174, Biochem. 35, 282-289. Impaktfaktor 2010: 3,226 6. van Damme, J., Jung, M., Hofmann, F., Just, I., Vanderkerckhove, J. and Aktories, K. (1996) Analysis of the catalytic site of the actin ADP-ribosylating Clostridium perfringens iota toxin. FEBS.Lett. 380, 291-295. Impaktfaktor 2010: 3,601 7. Schäfer, K.H., Jung, M. and Mestres, P. (1998) Protein extracts from the gut wall influence the postnatal development of rat myenteric neurons in vitro. Neuroscience Lett. 244, 177-179. Impaktfaktor 2010: 2,055 8. Liewen, H., Meinhold-Heerlein, I., Oliveira, V., Schwarzenbacher, R., Luo, G., Wadle, A., Jung, M., Pfreundschuh, M. and Stenner-Liewen, F. (2005) Characterization of the human GARP (Golgi associated retrograde protein) complex. Exp. Cell Res. 306, 24-34. Impaktfaktor 2010: 3,609 9. Brunner, E., Romeike, B., Jung, M., Comtesse, N. and Meese, E. (2006) Altered expression of beta-catenin/E-cadherin in meningiomas. Histopathology 49, 178-187. Impaktfaktor 2010: 3,596 10. Cizmowski, C., Jung, M., Erdmann, R. and Schliebs, W. (2011) A monoclonal antibody for in vitro detection of peroxisome-associated PTS1 receptor Hybridoma 30, 387-391. Impaktfaktor 2010: 0,462 11. Nicoll, W.S., Boshoff, A., Ludewig, M.H., Hennessy, F. , Jung, M. and Blatch, G.L. (2006) Approaches to the isolation and characterization of molecular chaperones. Prot. Exp. & Pur 46, 1-15. Impaktfaktor 2010: 1,644
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