Internal Medicine IV

The Department of Internal Medicine IV provides medical care for patients suffering from renal disease and hypertension. The department, which has been in existence for many years, is also home to the only university chair in nephrology in Saarland and Rhineland Palatinate. Equipped with advanced medical technology, our department is able to provide the highest quality diagnostic and therapeutic interventions for patients with renal and hypertensive disorders. We also run risk-factor consultation sessions to teach preventive strategies concerning in particular: hypertension, fat metabolism, excess weight, sedentary lifestyles, stress and medication. Patients found to be already suffering from advanced renal insufficiency will receive expert advice and, where necessary, will undergo kidney replacement therapy such as haemodialysis, peritoneal dialysis or kidney transplantation. Transplantations are carried out in cooperation with the Department of Urology. Besides receiving professional inpatient treatment, patients are also supervised in our numerous specialist consulting sessions. The research carried out at the department is mainly focused on cardiovascular complications in cases of chronic renal insufficiency, and infection monitoring in immunosuppressed patients. Our research programmes are supported by the German Research Council (DFG), the Else Kröner-Fresenius Foundation, the German José Carreras Leukaemia Foundation and other project-specific funds.

Fliser D, Seiler S, Heine GH, Ketteler M.

Measurement of serum soluble Klotho levels in CKD 5D patients: useful tool or dispensable biomarker?

Nephrol Dial Transplant 2012 May;27(5):1702-3. Impact factor: 3.6 Abstract

Rogacev KS, Pinsdorf T, Weingartner O, Gerhart MK, Welzel E, van Bentum K, Popp J, Menzner A, Fliser D, Lutjohann D, Heine GH.

Cholesterol Synthesis, Cholesterol Absorption, and Mortality in Hemodialysis Patients.

Clin J Am Soc Nephrol 2012 Mar 29. Impact factor: 4.8 Abstract

Heine GH, Ortiz A, Massy ZA, Lindholm B, Wiecek A, Martinez-Castelao A, Covic A, Goldsmith D, Suleymanlar G, London GM, Parati G, Sicari R, Zoccali C, Fliser D.

Monocyte subpopulations and cardiovascular risk in chronic kidney disease.

Nat Rev Nephrol 2012 Mar 13. Impact factor: 4.8 Abstract

Rogacev KS, Zawada AM, Heine GH.

CKD-associated atherosclerosis and monocyte heterogeneity.

Kidney Int 2012 Mar;81(6):599. Impact factor: 6.1 Abstract

Claudia Adam
BK virus-specific immune responses are age-dependent and strongly correlate with phases of virus replication
State-of-the-Art Symposium "CMV: Updates and Advances"

The Transplantation Society TTS, Berlin, 15.-20.7.2012