Original Articles
Gadjanski I, Boretius S, Williams SK, Lingor P, Knöferle J, Sättler MB, Fairless R, Hochmeister S, Sühs KW, Michaelis T, Frahm J, Storch MK, Bähr M, Diem R. (2009) Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis. Ann Neurol. 66:81-93
Sättler MB, Williams SK, Neusch C, Otto M, Pehlke JR, Bähr M, Diem R. (2008) Flupirtine as neuroprotective add-on therapy in autoimmune optic neuritis. Am J Pathol. 173:1496-507.
Diem R, Demmer I, Boretius S, Merkler D, Schmeting B, Williams SK, Sättler MB, Bähr M, Michaelis T, Frahm J, Brück F, Fuchs E (2008) Autoimmune optic neuritis in the common marmoset monkey: Comparison of visual evoked potentials with MRI and histopathology. Invest Opthalmol Vis Sci, 49:3707-3714.
Hein K, Köhler A, Diem R, Sättler MB, Demmer I, Lange P, Bähr M, Otto M (2008) Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative of multiple sclerosis. Neurosci Lett 436: 72-76.
Boretius S, Gadjanski I, Demmer I, Bähr M, Diem R, Michaelis T, Frahm J (2008) MRI of optic neuritis in a rat model. Neuroimage, 41: 323-334.
Sättler, MB, Togni M, Gadjanski I, Sühs KW, Meyer N, Bähr M, Diem R (2008) Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis. J Neuroimmunol. 193:77-86.
Maier K, Merkler D, Gerber J, Taheri N, Kuhnert AV, Williams SK, Neusch C, Bähr M, Diem R (2007) Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation. Neurobiol Dis 25:514-25.
Maier K, Kuhnert AV, Taheri N, Sättler MB, Storch MK, Williams SK, Bähr M, Diem R (2006) Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study. Am J Pathol 169:1353-1364.
Walter S, Doering A, Letiembre M, Liu Y, Hao W, Diem R, Bernreuther C, Glatzel M, Engelhardt B, Fassbender K (2006) The LPS receptor, CD 14 in experimental autoimmune encephalomyelitis and multiple sclerosis. Cell Physiol Biochem 17: 167-72.
Sättler MB, Demmer I, Williams SK, Maier K, Merkler D, Gadjanski I, Stadelmann C, Bähr M, Diem R (2006) Effects of Interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Exp Neurol 201:172-81.
Diem R, Sättler MB, Merkler D, Demmer I, Maier K, Stadelmann C, Ehrenreich H, Bähr M (2005) Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis. Brain 128:375-385.
Diem R, Taheri N, Dietz GPH, Kuhnert A, Maier K, Sättler MB, Gadjanski I, Merkler D, Bähr M (2005) HIV-Tat-mediated Bcl-XL delivery protects retinal ganglion cells during experimental autoimmune optic neuritis. Neurobiol Dis 20:218-226.
Rostasy K, Withut E, Pohl D, Lange P, Ciesielcyk B, Diem R, Gärtner J, Otto M (2005) Tau, Phospho-Tau and S-100B in cerebrospinal fluid of children with multiple sclerosis. J Child Neurol 20:822-825.
Sättler MB, Diem R, Merkler D, Demmer I, Boger I, Stadelmann C, Bähr M (2005) Simvastatin treatment does not protect retinal ganglion cells from degeneration in a rat model of autoimmune optic neuritis. Exp Neurol 193:163-171.
Wellmer A, von Mering M, Spreer A, Diem R, Eiffert H, Noeske C, Bunkowski S, Gold R, Nau R (2004) Experimental pneumococcal meningitis: impaired clearance of bacteria from the blood in Bcl-2-deficient mice due to increased apoptosis in the spleen. Infect Immun 72:3113-9.
Sättler MB (née Hobom), Merkler D, Maier K, Stadelmann C, Ehrenreich H, Bähr M, Diem R (2004) Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell Death Differ 11:S181-192.
Maier K, Rau CR, Storch MK, Sättler MB, Demmer I, Weissert R, Taheri N, Kuhnert AV, Bähr M, Diem R (2004) Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats. Brain Pathol 14:378-387.
Hobom M, Storch MK, Weissert R, Maier K, Radhakrishnan A, Kramer B, Bähr M, Diem R (2004) Mechanisms and time course of neuronal degeneration in experimental autoimmune encephalomyelitis. Brain Pathol 14:148-157.
Weishaupt JH, Diem R, Kermer P, Kikly KK, Krajewsky S, Reed JC, Bähr M (2003) Cell-surface-death-receptor-independent contribution of caspase-8 to apoptosis of CNS neurons in vivo. Neurobiol Dis 13:124-135.
Diem R, Tschirne A, Bähr M (2003) Decreased amplitudes in multiple sclerosis patients with normal visual acuity: a VEP study. J Clin Neurosci 10:67-71.
Diem R, Hobom M, Maier K, Weissert R, Storch MK, Meyer R, Bähr M (2003) Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci 23:6993-7000.
Diem R, Hobom M, Grötsch P, Kramer B, Bähr M (2003) Interleukin-1 β protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo. Mol Cell Neurosci 22:487-500.
Meyer R, Weissert R, Diem R, Storch MK, de Graaf KL, Kramer B, Bähr M (2001) Acute neuronal apoptosis in a rat model of multiple sclerosis. J Neurosci 21:6214-6220.
Diem R, Meyer R, Weishaupt JH, Bähr M (2001) Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent Akt phosphorylation by tumor necrosis factor-α rescues axotomized retinal ganglion cells from retrograde cell death in vivo. J Neurosci 21:2058-2066.