AG 3 - Vascular Biology and Lipoprotein Metabolism
Team members
| Prof. Dr. med. Danilo Fliser | Principal Investigator | 06841/16-23526 | Danilo.Fliser @uks.eu |
| Dr. med. Dr. sc. nat. Timo Speer | Group Leader | 06841/16-21501 oder 15001 Fax: 06841/16-1721503 | Timo.Speer @uks.eu |
Scientific Staff | |||
| Mira Klug | M. Sc. | 06841/16-23542 | Mira.Klug @uks.eu |
| Dr. Ioannis Petrakis | Postdoc | 06841/16-23542 | Ioannis.Petrakis @uks.eu |
| Dr. David Schmit | Postdoc | 06841/16-23542 | David.Schmit @uks.eu |
| Dr. Stefan Schunk | Postdoc | 06841/16-23542 | Stefan.Schunk @uks.eu |
| Dr. med. Stephen Zewinger | Postdoc | 06841/16-21503 | Stephen.Zewinger @uks.eu |
| Sarah Triem | M. Sc. | 06841/16-23542 | Sarah.Triem @uks.eu |
Technical Staff | |||
| Sophia Klahm | Technician | 06841/16-23542 | Sophia.Klahm @uks.eu |
| Claudia Noll | Technician | 06841/16-23512 | Claudia.Noll @uks.eu |
Doctoral Students | |||
| Felix Frenzel | cand. med. | ||
| Tobias Herter | cand. med. | ||
| Andreas Jung | cand. med. | ||
| Marlene Lehmann | cand. med., B.Sc. | ||
| Anna Paschen | cand. med. | ||
| Julia Riffel | cand. med. | ||
| Gabriel Wernicke | cand. med. |
Research Topics
- Regulation of vascular function and regeneration by lipoproteins (high-density lipoproteins, HDL and low-density lipoproteins, LDL)
- Effects of Chronic Kidney Disease (CKD) on metabolism and vascular function of HDL and LDL
- Modulation of innate immunity by lipoproteins
- Remodeling of lipoproteins (lipid and protein modifications) in patients with CKD
- Regulation of vascular calcification in patients with CKD
External Collaboration
- University Hospital Zurich, Cardiovascular Center, Cardiology, Zurich, Switzerland
Prof. Dr. T. F. Lüscher, Prof. Dr. Landmesser
- University Hospital Zurich, Institute of Clinical Chemistry, Zurich, Switzerland
Prof. Dr. A. von Eckardstein, Dr. L. Rohrer
- University Zurich, Institute of Physiology, Zurich, Switzerland
Prof. Dr. O. Devuyst
- Great Ormond Street Hospital for Children, London, Great Britain
Dr. R. Shroff
- Great Ormond Street Hospital for Children, London, Great Britain
Prof. Dr. J. Deanfield
- University Hospital Mannheim, Mannheim Institute of Public Health, Mannheim, Germany
Prof. Dr. W. März
Internal Collaboration (Saarland University Hospital)
- Department of Internal Medicine, Cardiology
Prof. Dr. M. Böhm, Prof. Dr. U. Laufs, Dr. F. Mahfoud
- Institute of Clinical Chemistry
Prof. Dr. J. Geisel
- Institute of Transplantation Immunology
Prof. Dr. M. Sester
- Department of Internal Medicine, Pneumology
Prof. Dr. R. Bahls, Dr. P. Lepper
- Institute of Biophysics
Dr. R. Kappl
- Department of Anaesthesiology
Prof. Dr. T. Volk, Dr. T. Fink
Experimental techniques
- Transgenic mouse models, conditional knock-out
- Small animal models of acute kidney injury and chronic kidney disease
- In vitro and in vivo modulation of gene expression
- RT-PCR methods, molecular cloning
- Metabolic studies of small animals: metabolic cages, special diets
- Electron-spin resonance spectroscopy (ESR)
- Immortalized cell lines and primary cell culture models
- Immunoblotting, immunoprecipitation
- Immunohistochemistry, cytochemistry
- Biochemical analyses in rodent samples
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