Medizinische Fakultät der Universität des Saarlandes
Biophysik
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1992 1993 1994 1995 1996 1997 1998 1999
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009
2010 2011 2012 2013 2014 2015 2016 2017

 

Publications 2017 :

 


 

Publications 2016 :

 

Thiol dependent intramolecular locking of Orai1 channels.

Alansary D, Schmidt B, Dörr K, Bogeski I, Rieger H, Kless A, Niemeyer BA.

Sci Rep. 2016 Sep 14;6:33347. doi: 10.1038/srep33347.

 

Visualizing Quantum Dot Labeled ORAI1 Proteins in Intact Cells Via Correlative Light and Electron Microscopy.

Peckys DB, Alansary D, Niemeyer BA, de Jonge N.

Microsc Microanal. 2016 Aug;22(4):902-12. doi: 10.1017/S1431927616011491.

 

A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.

Saul S, Gibhardt CS, Schmidt B, Lis A, Pasieka B, Conrad D, Jung P, Gaupp R, Wonnenberg B, Diler E, Stanisz H, Vogt T, Schwarz EC, Bischoff M, Herrmann M, Tschernig T, Kappl R, Rieger H, Niemeyer BA, Bogeski I.

Sci Signal. 2016 Mar 8;9(418):ra26.

 

Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry.

Dörr K, Kilch T, Kappel S, Alansary D, Schwär G, Niemeyer BA, Peinelt C.

Sci Signal. 2016 Mar 8;9(418):ra25.

 

Changing calcium: CRAC channel (Orai and STIM) expression, splicing and posttranslational modifiers.

Niemeyer BA.

Am J Physiol Cell Physiol. 2016 Feb 24:ajpcell.00034.2016. [Epub ahead of print]

 


 

Publications 2015 :

 

Facilitation of Orai3 targeting and store-operated function by Orai1.
Alansary D, Bogeski I, Niemeyer BA.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2015 Mar; 1853(7):1541-1550.

 

A STIM2 splice variant negatively regulates store-operated calcium entry.

Miederer AM, Alansary D, Schwär G, Lee PH, Jung M, Helms V, Niemeyer BA.

Nat Commun. 2015 Apr 21;6:6899. doi: 10.1038/ncomms7899.

 


 

Publications 2014 :

 

Redox regulation of ion channels.

Bogeski I, Niemeyer BA.

Antioxid Redox Signal. 2014 Aug 20;21(6):859-62. doi: 10.1089/ars.2014.6019. Epub 2014 Jul 8.

 

Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry.

Stanisz H, Saul S, Müller CS, Kappl R, Niemeyer BA, Vogt T, Hoth M, Roesch A, Bogeski I.

Pigment Cell Melanoma Res. 2014 May;27(3):442-53. doi: 10.1111/pcmr.12222. Epub 2014 Mar 7.

 


 

Publications 2013 :

 

Carreras-Sureda A, Cantero-Recasens G, Rubio-Moscardo F, Kiefer K, Peinelt C, Niemeyer BA

ORMDL3 modulates store-operated calcium entry and lymphocytes activation.

Hum Mol Genet 2013 Feb;22(3):519-30.

 

Hoth M, Niemeyer BA.

The Neglected CRAC Proteins: Orai2, Orai3, and STIM2.

Curr Top Membr. 2013;71:237-71.

 


 

Publications 2012 :

 

Kilch T, Alansary D, Peglow M, Doerr K, Rychkov G, Rieger H, Peinelt C, Niemeyer BA.

Mutations of the Ca2+-sensing Stromal Interaction Molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1

Journal of Biological Chemistry. 2012 Dec 04;

 

Bogeski I, Kilch T, Niemeyer BA.

ROS and SOCE: recent advances and controversies in the regulation of STIM and Orai.

J Physiol. 2012 Sep 1;590(Pt 17):4193-200. doi: 10.1113/jphysiol.2012.230565. Epub 2012 May 21.

 

Mishina NM, Bogeski I, Bolotin DA, Hoth M, Niemeyer BA, Schultz C, Zagaynova EV, Lukyanov S, Belousov VV.

Can we see PIP(3) and hydrogen peroxide with a single probe?

Antioxid Redox Signal. 2012 Aug 1;17(3):505-12. doi: 10.1089/ars.2012.4574. Epub 2012 Apr 10.

 

Stanisz H, Stark A, Kilch T, Schwarz EC, Müller CS, Peinelt C, Hoth M, Niemeyer BA, Vogt T, Bogeski I.

ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes.

Journal of Investigative Dermatology. 2012 May; 132(5): 1443–1451.

 


 

Publications 2011 :

 

Niemeyer BA, Hoth M.

Excitable T cells: ca(v)1.4 channel contributions and controversies.

Immunity. 2011 Sep 23;35(3):315-7.

 

Bogeski I, Kappl R, Kummerow C, Gulaboski R, Hoth M, Niemeyer BA.

Redox regulation of calcium ion channels: Chemical and physiological aspects.

Cell Calcium. 2011 Sep 17. [Epub ahead of print]

 

Quintana A, Pasche M, Junker C, Al-Ansary D, Rieger H, Kummerow C, Nuñez L, Villalobos C, Meraner P, Becherer U, Rettig J, Niemeyer BA, Hoth M.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

The EMBO Journal advance online publication 16 August 2011; doi:10.1038/emboj.2011.289 Published online: 16 August 2011

 


 

Publications 2010 :

 

Quintana A, Pasche M, Al-Ansary D, Junker C, Nuñez L, Villalobos C, Becherer U, Rettig J, Niemeyer BA, Hoth M.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

(Immunity, resubmitted)


Bogeski I, Al-Ansary D, Qu B, Niemeyer BA, Hoth M, Peinelt C.

Pharmacology of ORAI channels as a tool to understand their physiological functions.

Expert Review of Clinical Pharmacology. 2010 May;3(3):291-303.


Bogeski I, Kummerow C, Al-Ansary D, Schwarz EC, Koehler R, Kozai D, Takahashi N, Peinelt C, Griesemer D, Bozem M, Mori Y, Hoth M, Niemeyer BA.

Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling.

Science Signaling. 2010 March 13;3(115):ra24.

 

Al-Ansary D, Bogeski I, Disteldorf BM, Becherer U, Niemeyer BA.

ATP modulates Ca2+ uptake by TRPV6 and is counteracted by isoform-specific phosphorylation.

FASEB J. (2010 Feb);24(2):425-35. Epub 2009 Oct 5.

 


 

Publications 2007 :

 

Wissenbach U, Niemeyer BA

TRPV6

Handbook of Experimental Pharmacology HEP. 2006;179:221-236.



 

Publications 2006 :

 

Erler I, Al-Ansary D, Wissenbach U, Wagner TFJ, Flockerzi V, Niemeyer BA.
Trafficking and Assembly of the cold-sensitive TRPM8 channel.

J Biol Chem. 2006 Dec 15;281(5):38396-38404.


Schwarz EC, Wissenbach U, Niemeyer BA, Strauß B, Philipp S, Flockerzi V and Hoth M.

TRPV6 potentiates calcium-dependent cell proliferation.

Cell Calcium. 2006 Feb;39(2):163-173.



 

Publications 2005 :

 

Niemeyer BA.

Structure-function analysis of TRPV channels.

Naunyn-Schmiedebergs Arch. Pharmacol. 2005 Apr;371(4):285-294.



 

Publications 2004 :

 

Wissenbach U, Niemeyer B, Himmerkus N, Fixemer T, Bonkhoff H, Flockerzi V.

TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression.

Biochem Biophys Res Commun. 2004 Oct;322(4):1359-1363.

 

Erler I, Hirnet D, Wissenbach U, Flockerzi V, and Niemeyer BA.

Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat.

J Biol Chem. 2004 Aug 13;279:34456-34463.


Wissenbach U, Niemeyer BA, Flockerzi V.

TRP channels as potential drug targets.

Biol Cell. 2004 Feb;96(1):47-54.

 


 

Publications 2002 :

 

Bhattacharya S, Stewart BA, Niemeyer BA, Burgess RW, McCabe BD, Lin P, Boulianne G, O'Kane CJ, Schwarz TL.

Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally
interchangeable in vivo for neurotransmitter release and cell viability
.

Proc Natl Acad Sci USA, 99. 2002 Oct 15;99(21):13867-13872.

 


 

Publications 2001 :

 

Wissenbach U, Niemeyer BA, Fixemer T, Schneidewind A, Trost C, Cavalie A, Reuss K, Meese E, Bonkhoff H, Flockerzi V.

Expression of CaT-Like, a novel calcium selective channel, correlated with the malignancy of prostate cancer.

J. Biol. Chem. 2001 Jun 1;276:19461-19468.

 

Niemeyer BA, Mery L, Zawar C, Suckow A, Monje F, Pardo LA, Stuhmer W, Flockerzi V, Hoth M.

Ion channels in health and disease: 83rd Boehringer Ingelheim Fonds International Titisee Conference.

EMBO Rep. 2001 May 7;2:568-573.

 

Niemeyer BA, Bergs C, Wissenbach U, Flockerzi V, Trost C.

Competitive regulation of CaT-L mediated Ca2+ entry by protein kinase C and calmodulin.

Proc Natl Acad Sci USA. 2001 Jan 5;98(6):3600-3605.

 


 

Publications 2000 :

 

Niemeyer BA, Schwarz TL.

SNAP-24, a Drosophila SNAP-25 homologue on granule membranes, is a putative mediator of secretion and granule-granule fusion in salivary glands protein secretion.

J Cell Sci. 2000 Sep;113:4055-4064.



 

Publications 1996 :

 

Niemeyer BA, Suzuki E, Scott K, Jalink K and Zuker CS.

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

Cell. 1996;85(5):651-659.



 

Publications 1995 :

 

Wu L, Niemeyer B, Colley N, Socolich M and Zuker CS.

Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase.

Nature. 1995 Jan 19;373:216-222.

 

Shieh B-H and Niemeyer BA.

A novel protein encoded by the InaD gene regulates recovery of visual transduction in Drosophila.

Neuron. 1995 Jan;14(1):201-210.

 


 

Publications 1993 :

 

Stieve H, Benner S, Niemeyer B, Reuss H.

Trifurcated signal transduction sequence of the photoreceptor cell of Limulus. Sensory Systems of Arthropods.

Ed. K. Wiese et al. Birkhäuser Verlag Basel/Switzerland. 1993;:91-99.




Publications 1992 :

 

Stieve H, Niemeyer B, Aktories K, Hamm HE.

Disturbing GTP-binding protein function through microinjection into the visual cell of Limulus.

Journal of Biosciences. 1992 Nov-Dec;47(11-12):915-921.