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Medizinische Biochemie und Molekularbiologie
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Sie befinden sich hier: >> Startseite >> Einrichtungen >> Fachrichtungen Theoretische und Klinische Medizin >> Biochemie >> AG Prof. Dr. Gabriel Schlenstedt >> Veröffentlichungen / Publications

Publications

Hahn, S. and Schlenstedt, G. (2011) Importin β-type nuclear transport receptors have distinct binding affinities for Ran–GTP. Biochem. Biophys. Res. Commun. 406, 383-388. Abstract | Full Text | PDF

 

Chang, Y., Schlenstedt, G., Flockerzi, V. and Beck, A. (2010) Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1. FEBS Lett. 584, 2028-2032. Abstract | Full Text | PDF


Kim, K.-Y., Truman, A.W., Caesar, S., Schlenstedt, G. and Levin, D.E. (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator. Mol. Biol. Cell 21, 1609-1619. Abstract | Full Text | PDF


Neuber, A., Franke, J., Wittstruck, A., Schlenstedt, G., Sommer, T. and Stade, K. (2008) The nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast. Mol. Cell. Biol. 28, 5348-5358. Abstract | Full Text | PDF


Hahn, S., Maurer, P., Caesar, S. and Schlenstedt, G. (2008) Classical NLS proteins from Saccharomyces cerevisiae. J. Mol. Biol. 379, 678-694. Abstract | Full Text | PDF | Suppl. data PDF


Fries, T., Betz, C., Sohn, K., Caesar, S., Schlenstedt, G. and Bailer, S.M. (2007) A novel conserved nuclear localization signal is recognized by a group of yeast importins. J. Biol. Chem. 282, 19292-19301. Abstract | Full Text | PDF


Bakhrat, A., Baranes, K., Krichevsky, O., Rom, I., Schlenstedt, G., Pietrokovski, S. and Raveh, D. (2006) Nuclear import of Ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system. J. Biol. Chem. 281, 12218-12226. Abstract | Full Text | PDF


Caesar, S., Greiner, M. and Schlenstedt, G. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. Mol. Cell. Biol. 26, 3170-3180. Abstract | Full Text | PDF | Suppl. data PDF


Cook, A., Fernandez, E., Lindner, D., Ebert, J., Schlenstedt, G. and Conti, E. (2005) The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Mol. Cell 18, 355-367. Abstract | Full Text | PDF | Suppl. data PDF


Greiner, M., Caesar, S. and Schlenstedt, G. (2004) The histones H2A/H2B and H3/H4 are imported into the yeast nucleus by different mechanisms. Eur. J. Cell Biol. 83, 511-520. Abstract | PDF


Betz, C., Schlenstedt, G. and Bailer, S.M. (2004) Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus. J. Biol. Chem. 279, 28174-28181. Abstract | Full Text | PDF


Maurer, P., Redd, M., Solsbacher, J., Bischoff, F.R., Greiner, M., Podtelejnikov, A.V., Mann, M., Stade, K., Weis, K. and Schlenstedt, G. (2001) The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p). Mol. Biol. Cell 12, 539-549. Abstract | Full Text | PDF


Solsbacher, J., Maurer, P., Vogel, F. and Schlenstedt, G. (2000) Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin α. Mol. Cell. Biol. 20, 8468-8479. Abstract | Full Text | PDF


Schlenstedt, G. and Solsbacher, J. (1999) Transport between the cytoplasm and the nucleus. Protoplasma 209, 166-172. Review. Abstract | PDF


Elliott, S., Knop, M., Schlenstedt, G. and Schiebel, E. (1999) Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication. Proc. Natl. Acad. Sci. USA 96, 6205-6210. Abstract


Silberstein, S., Schlenstedt, G., Silver, P.A. and Gilmore, R. (1998) A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum. J. Cell Biol. 143, 921-933. Abstract


Kahana, J.A., Schlenstedt, G., Evanchuk, D.M., Geiser, J.R., Hoyt, M.A and Silver, P.A. (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol. Biol. Cell 9, 1741-1756. Abstract


Solsbacher, J., Maurer, P., Bischoff, F.R. and Schlenstedt, G. (1998) Cse1p is involved in export of yeast importin α from the nucleus. Mol. Cell. Biol. 18, 6805-6815. Abstract | Full Text | PDF


Taura, T., Schlenstedt, G. and Silver, P.A. (1997) Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. J. Biol. Chem. 272, 31877-31884. Abstract


Schlenstedt, G., Smirnova, E., Deane, R., Solsbacher, J., Kutay, U., Görlich, D., Ponstingl, H. and Bischoff, F.R. (1997) Yrb4p, a yeast Ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. EMBO J. 16, 6237-6249. Abstract | Full Text | PDF


Dierks, T., Volkmer, J., Schlenstedt, G., Jung, C., Sandholzer, U., Zachmann, K., Schlotterhose, P., Neifer, K., Schmidt, B. and Zimmermann, R. (1996) A microsomal ATP-binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum. EMBO J. 15, 6931-6942. Abstract


Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E., Taura, T., Wong, D., Silver, P. (1996) Genetic analysis of macromolecular transport across the nuclear envelope. Exp. Cell Res. 229, 212-216. Review. Abstract


Schlenstedt, G. (1996) Protein import into the nucleus. FEBS Lett. 389, 75-79. Review. Abstract | PDF


Schlenstedt, G., Wong, D.H., Koepp, D.M. and Silver, P.A. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J. 14, 5367-5378. Abstract | PDF


Corbett, A.H., Koepp, D.M., Schlenstedt, G., Lee, M.S., Hopper, A.K. and Silver, P.A. (1995) Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J. Cell Biol. 130, 1017-1026. Abstract | PDF


Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P.A. and Fink, G.R. (1995) The yeast nuclear import receptor is required for mitosis. Proc. Natl. Acad. Sci. USA 92, 7647-7651. Abstract | PDF


Schlenstedt, G., Saavedra, C., Loeb, J.D.J., Cole, C.N. and Silver, P.A. (1995) The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly (A)+ RNA in the cytoplasm. Proc. Natl. Acad. Sci. USA 92, 225-229. Abstract | PDF


Schlenstedt, G., Harris, S., Risse, B., Lill, R. and Silver, P.A. (1995) A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. J. Cell Biol. 129, 979-988. Abstract


Osborne, M.A., Schlenstedt, G., Jinks, T. and Silver, P.A. (1994) Nuf2, a spindle pole body-associated protein required for nuclear division in yeast. J. Cell Biol. 125, 853-866. Abstract


Schlenstedt, G., Zimmermann, M. and Zimmermann, R. (1994) A stably folded presecretory protein associates with and upon unfolding translocates across the membrane of mammalian microsomes. FEBS Lett. 340 139-144. Abstract


Schlenstedt, G., Hurt, E., Doye, V. and Silver, P. A. (1993) Reconstitution of nuclear transport with semi-intact yeast. J. Cell Biol. 123, 785-798. Abstract | PDF


Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. and Zimmermann, R. (1992) Structural requirements for transport of preprocecropin A and related presecretory proteins into mammalian microsomes. J. Biol. Chem. 267, 24328-24332. Abstract


Klappa, P., Müller, G., Schlenstedt, G., Wiech, H. and Zimmermann, R. (1992) Consecutive steps of nucleoside triphosphate-hydrolysis are driving transport of precursor proteins into the endoplasmic reticulum, New Comprehensive Biochemistry 22, 137-146. Review.


Zimmermann, R., Zimmermann, M., Wiech, H., Schlenstedt, G., Müller, G., Morel, F., Klappa, P., Jung, C. and Cobet, W.W. (1990) Ribonucleoparticle-independent transport of proteins into mammalian microsomes. J. Bioenerg. Biomembr. 22, 711-723. Review. Abstract


Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. and Zimmermann, R. (1990) A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes. J. Biol. Chem. 265, 13960-13968. Abstract


Schlenstedt, G., Wachter, E., Sagstetter, M., Morel, F., Zimmermann, R., Gudmundsson, G.H. and Boman, H.G. (1990) Import of preprocecropin A and related precursor proteins into the endoplasmic reticulum, in "Dynamics and Biogenesis of Membranes" (Op den Kamp, J.A.F., ed.) Springer Verlag, Berlin-Heidelberg, 311-326.


Zimmermann, R., Sagstetter, M. and Schlenstedt, G. (1990) Ribonucleoparticle-independent import of proteins into mammalian microsomes involves a membrane protein which is sensitive to chemical alkylation. Biochimie 72, 95-101. Abstract


Schlenstedt, G., Cobet, W.W., Wiech, H. and Zimmermann, R. (1989) Mechanisms of protein import into the endoplasmic reticulum and protein export in Escherichia coli. Biochem. Soc. Trans. 17, 822-823. Review.


Boman, H.C., Boman, I.A., Andreu, D., Li, Z.Q., Merrifield, R.B., Schlenstedt, G. and Zimmermann, R. (1989) Chemical synthesis and enzymic processing of precursor forms of cecropins A and B. J. Biol. Chem. 264, 5852-5860. Abstract


Zimmermann, R., Sagstetter, M., Schlenstedt, G., Wiech, H.,  Kaßeckert, B. and Müller, G. (1988) Import of small secretory and  plasma membrane proteins into the endoplasmic reticulum, in  "Membrane Biogenesis" (Op den Kamp, J.A.F., ed.) Springer Verlag,  Berlin-Heidelberg, 337-350.


Müller, G., Schlenstedt. G., Wiech, H. and Zimmermann, R. (1988) Import of proteins into the endoplasmic reticulum. Biochem. Soc. Trans. 16, 708-709. Review.


Schlenstedt, G. and Zimmermann, R. (1987) Import of frog prepropeptide GLa into microsomes. EMBO J. 6, 699-703. Abstract

Chang, Y., Schlenstedt, G., Flockerzi, V. and Beck, A. (2010) Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1. FEBS Lett. In press. Abstract | Full Text | PDF

Kim, K.-Y., Truman, A.W., Caesar, S., Schlenstedt, G. and Levin, D.E. (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator. Mol. Biol. Cell 21, 1609-1619. Abstract | Full Text | PDF

Neuber, A., Franke, J., Wittstruck, A., Schlenstedt, G., Sommer, T. and Stade, K. (2008) The nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast. Mol. Cell. Biol. 28, 5348-5358. Abstract | Full Text | PDF

Hahn, S., Maurer, P., Caesar, S. and Schlenstedt, G. (2008) Classical NLS proteins from Saccharomyces cerevisiae. J. Mol. Biol. 379, 678-694. Abstract | Full Text | PDF | Suppl. data PDF

Fries, T., Betz, C., Sohn, K., Caesar, S., Schlenstedt, G. and Bailer, S.M. (2007) A novel conserved nuclear localization signal is recognized by a group of yeast importins. J. Biol. Chem. 282, 19292-19301. Abstract | Full Text | PDF

Bakhrat, A., Baranes, K., Krichevsky, O., Rom, I., Schlenstedt, G., Pietrokovski, S. and Raveh, D. (2006) Nuclear import of Ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system. J. Biol. Chem. 281, 12218-12226. Abstract | Full Text | PDF

Caesar, S., Greiner, M. and Schlenstedt, G. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. Mol. Cell. Biol. 26, 3170-3180. Abstract | Full Text | PDF | Suppl. data PDF

Cook, A., Fernandez, E., Lindner, D., Ebert, J., Schlenstedt, G. and Conti, E. (2005) The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Mol. Cell 18, 355-367. Abstract | Full Text | PDF | Suppl. data PDF

Greiner, M., Caesar, S. and Schlenstedt, G. (2004) The histones H2A/H2B and H3/H4 are imported into the yeast nucleus by different mechanisms. Eur. J. Cell Biol. 83, 511-520. Abstract | PDF

Betz, C., Schlenstedt, G. and Bailer, S.M. (2004) Asr1p, a novel yeast ring/PHD finger protein, signals alcohol stress to the nucleus. J. Biol. Chem. 279, 28174-28181. Abstract | Full Text | PDF

Maurer, P., Redd, M., Solsbacher, J., Bischoff, F.R., Greiner, M., Podtelejnikov, A.V., Mann, M., Stade, K., Weis, K. and Schlenstedt, G. (2001) The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p). Mol. Biol. Cell 12, 539-549. Abstract | Full Text | PDF

Solsbacher, J., Maurer, P., Vogel, F. and Schlenstedt, G. (2000) Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin α. Mol. Cell. Biol. 20, 8468-8479. Abstract | Full Text | PDF

Schlenstedt, G. and Solsbacher, J. (1999) Transport between the cytoplasm and the nucleus. Protoplasma 209, 166-172. Review. Abstract | PDF

Elliott, S., Knop, M., Schlenstedt, G. and Schiebel, E. (1999) Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication. Proc. Natl. Acad. Sci. USA 96, 6205-6210. Abstract

Silberstein, S., Schlenstedt, G., Silver, P.A. and Gilmore, R. (1998) A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum. J. Cell Biol. 143, 921-933. Abstract

Kahana, J.A., Schlenstedt, G., Evanchuk, D.M., Geiser, J.R., Hoyt, M.A and Silver, P.A. (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol. Biol. Cell 9, 1741-1756. Abstract

Solsbacher, J., Maurer, P., Bischoff, F.R. and Schlenstedt, G. (1998) Cse1p is involved in export of yeast importin α from the nucleus. Mol. Cell. Biol. 18, 6805-6815. Abstract | Full Text | PDF

Taura, T., Schlenstedt, G. and Silver, P.A. (1997) Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. J. Biol. Chem. 272, 31877-31884. Abstract

Schlenstedt, G., Smirnova, E., Deane, R., Solsbacher, J., Kutay, U., Görlich, D., Ponstingl, H. and Bischoff, F.R. (1997) Yrb4p, a yeast Ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. EMBO J. 16, 6237-6249. Abstract | Full Text | PDF

Dierks, T., Volkmer, J., Schlenstedt, G., Jung, C., Sandholzer, U., Zachmann, K., Schlotterhose, P., Neifer, K., Schmidt, B. and Zimmermann, R. (1996) A microsomal ATP-binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum. EMBO J. 15, 6931-6942. Abstract

Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E., Taura, T., Wong, D., Silver, P. (1996) Genetic analysis of macromolecular transport across the nuclear envelope. Exp. Cell Res. 229, 212-216. Review. Abstract

Schlenstedt, G. (1996) Protein import into the nucleus. FEBS Lett. 389, 75-79. Review. Abstract | PDF

Schlenstedt, G., Wong, D.H., Koepp, D.M. and Silver, P.A. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J. 14, 5367-5378. Abstract | PDF

Corbett, A.H., Koepp, D.M., Schlenstedt, G., Lee, M.S., Hopper, A.K. and Silver, P.A. (1995) Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J. Cell Biol. 130, 1017-1026. Abstract | PDF

Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P.A. and Fink, G.R. (1995) The yeast nuclear import receptor is required for mitosis. Proc. Natl. Acad. Sci. USA 92, 7647-7651. Abstract | PDF

Schlenstedt, G., Saavedra, C., Loeb, J.D.J., Cole, C.N. and Silver, P.A. (1995) The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly (A)+ RNA in the cytoplasm. Proc. Natl. Acad. Sci. USA 92, 225-229. Abstract | PDF

Schlenstedt, G., Harris, S., Risse, B., Lill, R. and Silver, P.A. (1995) A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. J. Cell Biol. 129, 979-988. Abstract

Osborne, M.A., Schlenstedt, G., Jinks, T. and Silver, P.A. (1994) Nuf2, a spindle pole body-associated protein required for nuclear division in yeast. J. Cell Biol. 125, 853-866. Abstract

Schlenstedt, G., Zimmermann, M. and Zimmermann, R. (1994) A stably folded presecretory protein associates with and upon unfolding translocates across the membrane of mammalian microsomes. FEBS Lett. 340 139-144. Abstract

Schlenstedt, G., Hurt, E., Doye, V. and Silver, P. A. (1993) Reconstitution of nuclear transport with semi-intact yeast. J. Cell Biol. 123, 785-798. Abstract | PDF

Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. and Zimmermann, R. (1992) Structural requirements for transport of preprocecropin A and related presecretory proteins into mammalian microsomes. J. Biol. Chem. 267, 24328-24332. Abstract

Klappa, P., Müller, G., Schlenstedt, G., Wiech, H. and Zimmermann, R. (1992) Consecutive steps of nucleoside triphosphate-hydrolysis are driving transport of precursor proteins into the endoplasmic reticulum, New Comprehensive Biochemistry 22, 137-146. Review.

Zimmermann, R., Zimmermann, M., Wiech, H., Schlenstedt, G., Müller, G., Morel, F., Klappa, P., Jung, C. and Cobet, W.W. (1990) Ribonucleoparticle-independent transport of proteins into mammalian microsomes. J. Bioenerg. Biomembr. 22, 711-723. Review. Abstract

Schlenstedt, G., Gudmundsson, G.H., Boman, H.G. and Zimmermann, R. (1990) A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes. J. Biol. Chem. 265, 13960-13968. Abstract

Schlenstedt, G., Wachter, E., Sagstetter, M., Morel, F., Zimmermann, R., Gudmundsson, G.H. and Boman, H.G. (1990) Import of preprocecropin A and related precursor proteins into the endoplasmic reticulum, in "Dynamics and Biogenesis of Membranes" (Op den Kamp, J.A.F., ed.) Springer Verlag, Berlin-Heidelberg, 311-326.

Zimmermann, R., Sagstetter, M. and Schlenstedt, G. (1990) Ribonucleoparticle-independent import of proteins into mammalian microsomes involves a membrane protein which is sensitive to chemical alkylation. Biochimie 72, 95-101. Abstract

Schlenstedt, G., Cobet, W.W., Wiech, H. and Zimmermann, R. (1989) Mechanisms of protein import into the endoplasmic reticulum and protein export in Escherichia coli. Biochem. Soc. Trans. 17, 822-823. Review.

Boman, H.C., Boman, I.A., Andreu, D., Li, Z.Q., Merrifield, R.B., Schlenstedt, G. and Zimmermann, R. (1989) Chemical synthesis and enzymic processing of precursor forms of cecropins A and B. J. Biol. Chem. 264, 5852-5860. Abstract

Zimmermann, R., Sagstetter, M., Schlenstedt, G., Wiech, H.,  Kaßeckert, B. and Müller, G. (1988) Import of small secretory and  plasma membrane proteins into the endoplasmic reticulum, in  "Membrane Biogenesis" (Op den Kamp, J.A.F., ed.) Springer Verlag,  Berlin-Heidelberg, 337-350.

Müller, G., Schlenstedt. G., Wiech, H. and Zimmermann, R. (1988) Import of proteins into the endoplasmic reticulum. Biochem. Soc. Trans. 16, 708-709. Review.

Schlenstedt, G. and Zimmermann, R. (1987) Import of frog prepropeptide GLa into microsomes. EMBO J. 6, 699-703. Abstract